We're pleased to announce registration and abstract submission for the 3rd annual WntUK meeting at the @cruk-si.bsky.social in Nov 2026 is now open! Now featuring a bonus ECR day preceding the main meeting, ECR speaker slot, travel grants, networking opportunities and social evening. Book via QR 👇

Presenting the March 2026 WntUK newsletter! Containing exciting information about our plans for the WntUK annual meeting being held across 16-17th November at the CRUK Scotland Institute. Please send us your new WntUK papers, vacancies, and funding for inclusion in future editions!

Beautiful new UK Wnt paper out now in @natgenet.nature.com by Peter Hohenstein, Andrew Wood and Derya Ozdemir @unileiden.bsky.social @edinburgh-uni.bsky.social and Koc University characterising the impact of numerous CTNNB1 mutational variants in human cancer. www.nature.com/articles/s41...

New UK Wnt paper out in @natgenet.nature.com from the Owen Sansom group at @cruk-si.bsky.social showing the RNA-binding protein NPM1 supports WNT-driven intestinal and liver tumorigenesis. www.nature.com/articles/s41...

Very grateful to receive a new BBSRC grant and many thanks to #BBSRC panel, and reviewers for this generous support. This funding will enable us to address important unresolved questions in chromatin regulation downstream of WNT/GSK3 signalling in stem cells. @wntuk.bsky.social

New posdoc position available in the Guettler lab @icr.ac.uk studying ADP-ribosylation in Wnt/B-catenin signalling and telomere maintenance 👇👇👇 jobs.icr.ac.uk/vacancies/12...

My next stop is CRUK Scotland in Glasgow. Thanks to Owen Sansom @cruk-si.bsky.social for hosting me. The @wntuk.bsky.social community is just awesome—great people, excellent research!

If you are interested in helping to organise and shape this event, I would love for you to join me!

Calling all WntUK ECRs! As the vision for a 2026 Wnt meeting takes shape we're planning a one-day ECR event. Interested in helping shape and organise it alongside our ECR rep @nadianasreddin.bsky.social? A great opportunity to connect, contribute, and develop your career. Get in touch!

Our latest work out now in Oncogene by Dr Megan Wagstaff at @biochembiomeduos.bsky.social @sussex.ac.uk @sussexcancer.org @sussexbcr.bsky.social @wntuk.bsky.social. We show the oncogene β-catenin interacts with a Wnt mRNA network in myeloid leukaemia cells Quick🧵👇 1/ www.nature.com/articles/s41...

Major congrats to Dr#3 from our group Okan Sevim who passed his PhD viva yesterday. A super talented researcher, it’s been a privilege to serve as Okan’s supervisor from MSc to PhD in @biochembiomeduos.bsky.social @sussex.ac.uk Many thanks to examiners @mitchell.science & @mardakheh.bsky.social

Such an honour! Thank you to the organising committee for the opportunity and the great conference!!

As the sun sets on a wonderful day of celebrating @wntuk.bsky.social research, we want to thank all attendees, presenters and sponsors for making this possible. @oxfordcancer.bsky.social, The Company of Biologists, Cambridge Biosciences, @thermofishersci.bsky.social

Honoured and humbled to win Best Talk at #WNTUK2025! This work reflects years of dedication and a fantastic team effort, led by the amazing Hayley Belnoue-Davis and myself, under the brilliant Simon Leedham. Grateful to all—soon to be in press! 🚀

Thank you for the opportunity to contribute; what a fantastic meeting hosted at the inspiring Oxford, on the coolest signalling pathway.

Really enjoyed #WNTUK2025 at @ox.ac.uk in beautiful Worcester College today. Excellent program of research talks and posters put together by @michaelranes.bsky.social and @oxfordcancer.bsky.social representing all themes, career stages and gender/diversity of @wntuk.bsky.social research. 👊

And that’s a wrap! @michaelranes.bsky.social draws a highly enjoyable, well organised and stimulating 2nd WNTUK meeting to a close, followed by drinks in the sun in front of a beautiful Worcester College lawn. See you next year! #WNTUK2025

Congratulations to @eoghanjm.bsky.social from @ox.ac.uk on winning best talk, and Kieran Hodson from the Toby Phesse group at @cardiffuni.bsky.social @ecscri.bsky.social on winning best poster! #WNTUK2025

The final talk of the day is our international keynote speaker @michaelboutros.bsky.social from @dkfz.bsky.social @uniheidelberg.bsky.social presenting a past and present overview on mechanisms of Wnt signal transduction. #WNTUK2025

The penultimate talk of the day is our best selected PhD talk by Dr Ben Broadway from the Guettler lab at @icr.ac.uk presenting on CRISPR approaches to uncovering new tankyrase regulatory mechanisms in Wnt/B-catenin signalling. #WNTUK2025

Many thanks WntUK ECR rep @nadianasreddin.bsky.social from @cruk-si.bsky.social for chairing the Future Generation session! #WNTUK2025

The final session of the day is a Future Generation focus starting with invited ECR speaker Dr Yeonjoo Kim from the @ianmcgough.bsky.social group at @babrahaminst.bsky.social presenting on a novel RASopathy caused by hyperactive non-canonical Wnt signalling. #WNTUK2025

Final talk of the disease session is a selected abstract from Nico Mueller of the de la Roche group at @cambridgeuni.bsky.social @cruk-ci.bsky.social speaking about novel LGR5 immunotherapeutics against multiple cancer types. #WNTUK2025

Next up another selected abstract this time from Dr Nuray Gunduz at the Sansom group at @cruk-si.bsky.social presenting her research on LGR4 maintenance of intestinal homeostasis and protection from mutant-cell clonal expansion. #WNTUK2025

Many thanks to @yatlasi.bsky.social from @qubelfastofficial.bsky.social for chairing the Disease and Translational Research session. #WNTUK2025

The Disease & Translational Research session begins with invited speaker Dr @vivianlilab.bsky.social from @crick.ac.uk presenting on SOX2 driven fetal reprogramming and reversible dormancy in colorectal cancer. #WNTUK2025

Lunch break means it’s WntUK poster time! We have 17 fabulous posters here today covering Wnt signalling across mechanisms, development and disease from all career stages. #WNTUK2025

We’ve paused for a glorious lunch break!

The final session before lunch is a selected abstract from Lee Placito Fellow of GI Cancer @eoghanjm.bsky.social from the @leedham-simon.bsky.social group at @ox.ac.uk speaking about GREMLIN1 role in stromal remodelling of Wnt-dependent ectopic stem niches in the intestine. #WNTUK2025

Taking us into the afternoon is the third selected abstract from Dr Ines Alvarez Rodrigo from the @jpvincentlab.bsky.social at the @crick.ac.uk presenting her research on Wnt secretion mechanisms at the membrane. #WNTUK2025

Many thanks to Dr Florencia Cavodeassi from @citystgeorges.bsky.social for chairing the Wnt Signalling in Development session. #WNT2025

We are incredibly grateful to our kind sponsors for the day @thermofishersci.bsky.social @biologists.bsky.social @oxfordcancer.bsky.social and @cambridgebio.bsky.social #WNTUK2025

Our invited speaker for the Wnt Signalling in Development session is Prof Denis Headon from @cmvm-edinburghuni.bsky.social presenting on Wnt signalling patterning of the Whisker Array. #WNTUK2025

The final talk of the morning session is a selected abstract from our international guests! Dr Michaela Holzem from @michaelboutros.bsky.social lab at @dkfz.bsky.social @uniheidelberg.bsky.social presents on PI3K regulation of Wg secretion in polarised tissue. All welcome at WntUK! #WNTUK2025

Our first selected oral presentation comes from Elisabeth Chapman from the @melissa-gammons1.bsky.social group at the CIMR @thecimr.bsky.social telling us about her research into casein kinase 1 regulation of Wnt signalosome assembly. #WNTUK2025

Many thanks to @matthias-krause.bsky.social from @kingscollegelondon.bsky.social for chairing the first session on Molecular Mechanisms of Wnt Signal Transduction. #WNTUK2025

The invited speaker for the opening Molecular Mechanisms of Wnt Signalling session is fellow conference organiser Prof Yvonne Jones from Nuffield Dept of Medicine Div of Structural Biology @ox.ac.uk revealing Structural insights into the extracellular modulation of Wnt signalling #WNTUK2025

Conference organiser and WntUK committee member @michaelranes.bsky.social from @ox.ac.uk @oxfordbiochemistry.bsky.social welcomes attendees and opens the meeting. #WNTUK2025

Getting ready to welcome #WNTUK2025 delegates 🤗 @wntuk.bsky.social

#WNT2025 is here! Safe journey to all our attendees en route to Worcester College at @ox.ac.uk this morning. We’ve a fantastic programme of research talks and posters showcasing the best of UK Wnt research and the scientists behind it! Follow here for live updates through the day.

Have a fabulous time at #WntUK2025 everyone! Look out for Yeon Kim, a postdoc in the McGough lab who was selected as WntUK’s first invited early career researcher 👏

We are less than a week away from the WntUK 2025 annual meeting in @ox.ac.uk @oxfordcancer.bsky.social To all our speakers, presenters and attendees we hope your preparations are going well and we look forward to seeing you Monday at Worcester College! Please tag #WntUK2025 in your posts!

New! 15y after the classic Aigouy et al "Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium..." from lab of much missed Suzanne Eaton, we provide our take from post-doc Sara Tan "Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing". rdcu.be/d81Vn

If you are working on cellular plasticity, don't miss out on this rare FASEB conference opportunity in May with fantastic speaker lineup! Abstract submission deadline: 3rd March We still have slots for selected short talks! Early bird registration below 👇 events.faseb.org/event/Cellul...

Welcome to #2 of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network! Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025 Yeon's Quickfire Q&A below 🧵1/

BBSRC fellowships are now open! If anyone is interested in applying to join my team and working on Wnt signalling, growth factor transport mechanisms, cytonemes and zebrafish @lsiexeter.bsky.social then send me a PM! www.ukri.org/opportunity/...

1/1 Our recent research sheds light on how Alzheimer's disease interferes with communication between brain cells. We identified a specific pathway (Wnt/PCP-ROR2) contributing to synapse loss, a crucial element in cognitive decline. tinyurl.com/4vh2uk3x @jcellsci.bsky.social @lsiexeter.bsky.social

Fantastic new canonical Wnt signalling review out now in @natrevmcb.bsky.social by Madeline Maurice and Stephane Angers. www.nature.com/articles/s41...

Early bird registration discount may have passed but #WNTUK2025 is still open for standard registration and abstract submission. Still plenty of speaker/poster slots available for all career levels and areas of Wnt signalling. Abstract deadline Feb 1st and we are just over 8 weeks from the big day!

Come to Oxford for one of the most interesting meetings of the year 2025.