Check out the latest work from our lab, led by Daniel Lin and Lara Elcavage: www.biorxiv.org/content/10.1... (1/3)

🚨 #RNAsky 🚨

🧬 New preprint! SNU-Seq maps nascent transcription at single-nucleotide resolution using 4sU labeling. Together with sf4sU-Seq, it shows how epigenetically primed chromatin rapidly activates transcription after IFN-γ. 📄 doi.org/10.1101/2021... #SNUSeq #RNAseq

Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...

new out in Nature www.nature.com/articles/d41...

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

The enzyme cGAS senses DNA damage, but in humans and mice it inhibits a DNA repair pathway (homologous recombination), which reduces genome stability. In naked mole-rats, altering 4 amino acids in cGAS changes its role: instead of hampering repair, it boosts it. www.science.org/doi/10.1126/...

New BBSRC funded PhD opportunity in my group with Inspiralis Ltd and @conradn.bsky.social. If you are interested in RNA - protein interactions and RNA modifications check the details below for how to apply. @nrpdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social tinyurl.com/bdzvn4dr

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756

We’re offering a 4y MRC PhD studentship with Fadri Martinez-Perez @mrc-lms.bsky.social Check it out! lms.mrc.ac.uk/work-and-stu...

Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story from my lab led by Frederick Rehfeld(@fred-rehfeld.bsky.social) which revealed that the answer is YES! Read on to find out how👇

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

Last week we were in the Washington Post for our characterization of Robertsonian chromosomes. This week we are entering our 10th day of being shut down and all of our research is on hold. To help me feel not-so-bad, here is a thread of some studies we released right before the shutdown 🧵 [1/n]...

Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team! Please repost! jobs.jic.ac.uk/Details.asp?...

Prestigious CRUK funded PhD studentship available in my lab for students with Black heritage backgrounds. See 👇Please apply and repost. UK home tuition fee status students only.

We are looking for our next PhD student to join us 🤩 www.mcclellandlab.com to understand cancer radiation therapy's impact on DNA damage repair and chromosomal instability. Prestigious funding from CRUK RadNet. Please contact me informally - deadline 5th Nov! crukradnet.colcc.ac.uk/phd-students...

#RNAsky 😎

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM. Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩 #RNA #cryoEM

AWESOME CONFERENCE ALERT!! I had an absolute blast at the Fusion “Genome Regulation Through RNA” meeting back in 2024, and psyched to see its upcoming return! Let’s geek out about all things Chromatin and RNA together, in Cancun! Talk abstract deadline: 10/17 Details👇

Check it out! The team at Acepodia reports efficacy of cetuximab-conjugated allogenic gamma/delta-T cells against EGFR+ tumors in mice, off-the-shelf, safer alternative to CAR-T. Currently in phase 1 clinical study (NCT06415487). Cell-surface chemistry for the win 👏 jitc.bmj.com/content/13/7...

David Baltimore passed away this weekend. A pioneer of molecular virology who won the Nobel prize in medicine & physiology for his discovery of viral reverse transcriptase. This essay he wrote in 2018 reflecting of his 60yr career in science is a great read. www.annualreviews.org/content/jour...

Looking forward to a few days of exciting discussions at the #EMBLProtein synthesis and translational control meeting www.embl.org/about/info/c...

Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky url: academic.oup.com/icb/article-...

I'm thrilled to share our work from @weissmanlab.bsky.social (www.sciencedirect.com/science/arti...). We developed LOCL-TL, an optogenetic approach for monitoring localized translation in mammalian cells. LOCL-TL revealed two distinct strategies for mitochondrially localized translation.

Super happy to announce that our science magazine initiative is now on #BlueSky. Follow @stemdoradoscimag.bsky.social for magazine life updates, release dates, kids contests, events we will attend to and more. All about making learning science and technology fun, inspiring and memorable for kids!

📣 New preprint 📣 We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation. Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)

Check out the latest study from our lab, led by Coffee Xiang (@coffeebond007.bsky.social) www.nature.com/articles/s41... (1/2)

This is a genuinely huge opportunity for the right person. We @dunnschool.bsky.social are proud not only of our discovery science to transform human health, but also of the support we offer early career fellows. Join us, and launch your independent career! Please share.

Exciting times!!🎉🍾

Woohoo! So psyched to see this awesome work from the Jovanovic lab out in the world! Congrats to all the authors on this tour-de-force! www.cell.com/cell/fulltex...

An outstanding opportunity - a great Institute in a beautiful city

Optogenetic storage and release of protein and mRNA in live cells and animals | Nature Communications share.google/gz8nYXZ3hUVh... #spatialbiology #imagingtools #fluorescencemicroscopy

Thinking about who's hanging out with you RNA in cells? Here's a super overview of the (many!) things you can do to find out. Many thanks @mardakheh.bsky.social @shechnerlab.bsky.social #RNA #RNAinteractome

It was a lot of fun writing this review with the amazing @shechnerlab.bsky.social! If you are looking for a review of the new RNA-centric methods to study RNA interactions, then look no more!

2 weeks left to apply for our new fully funded postdoc position studying plasticity regulators in metastatic CRC!

👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab! 👉 deadline 20/06 👇 check it out www.godinholab.com

Check out this amazing work from @genophoria.bsky.social’s lab, revealing a novel post-transcriptional tumour suppressive programme in breast cancer 👇👇

Are you interested in doing a masters in RNA biology? We are accepting students for 2-years masters by research degree (1 year research, 1 year write up). Only 1 year tuition fees (£25k international, £5k home) fees include bench fees normally worth £4k. @biouea.bsky.social www.theakaylab.com

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out

🚨🚨 News from the @castello-lab.bsky.social and @shabazlab.bsky.social. Our work, led by Louisa Iselin, reveals pervasive changes in the RNA-bound proteome induced by interferon. #RNA, #immunity, #interferon, #host-virus www.biorxiv.org/content/10.1...

Check out our paper about naked extracellular RNAs uptake, TLR signaling, endosomal escape, and the role of RNases in regulating this process. www.cell.com/cell-genomic...

New method drop: HCR-Proxy, a modular proximity labelling approach to profile local proteome composition around RNA at nanoscale, subcompartmental resolution. Thereby we resolved nested nucleolar layers and uncovered the grammar of spatial protein partitioning. www.biorxiv.org/content/10.1...

The deadline for this PhD is fast approaching. We are looking for a promising synthetic chemist to make new chemical biology tools to learn more about nucleic acid interactions. This is a collaborative project with the Trowbridge Lab in @uomscieng.bsky.social. If interested, get in touch soon!

👇👇👇Don’t miss this 👇👇👇

One of my favourite meetings! Registration deadline is 1st of June! Don't miss it!

Don’t miss this 👇

This is a fantastic paper, with huge implications for the study of DNA and binding proteins.Also, by combining this side by side to XRNAX, XDNAX might become the best way of addressing the challenging question of dual RNA/DNA binding proteins Huge congratulations to all involved!🎉🎉🎉 #ChromatinSky