Interesting preprint from the Boyce lab! Sec23IP (protein linking COPII inner and outer coats) is regulated by O-GlcNAcylation. Site-specific modification of its disordered domain controls O-GlcNAcylation, Sec31A recruitment, COPII assembly, and ER exit site function. www.biorxiv.org/content/10.6...

Here’s the highest-quality upload of the 60 minutes CECOT segment I’ve found so far: www.dailymotion.com/video/x9w8gyi

BREAKING: WATCH the full 60 Minutes CECOT segment here. This was sent to me anonymously. It appears to be the segment CBS' Bari Weiss killed. www.muellershewrote.com/p/watch-the-...

Chem 29N: Chemistry in the Kitchen (Winter 2026) with Prof. Richard Zare explores the chemistry behind everyday cooking. Through demos and tastings, students learn how science transforms food into great meals. Sign up today! #StanfordCourses #Winter2026 #ChemistryEd #Undergrad

My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...

Wow, exciting convergence of chem bio technologies in this paper! 🤯

The US is not Denmark. Denmark is not the US. The Danish immunization schedule is not adapted for the realities of the American Healthcare system and population. Let me explain. This is a long thread so buckle up 🧵

✨ Our first reactions article in @ACSCentralScience with #CyrilGoudet is officially out! 🎉 pubs.acs.org/doi/10.1021/... Don’t miss the chance to dive into the fantastic work of #AmadeuLlebaria #Xavier Rovira and #VenkateshKrishnan – truly a great read for the winter break! ❄️ 💛 #ProfLife #ChemBio

Multidisciplinary training, over time, produces the highest impact people www.science.org/doi/10.1126/...

14 two-year postdocs for academics of any nationality who cannot continue their research due to US politics. Do share if you know of such.

New heroes portrait of @michellemonje.bsky.social. A physician scientist at Stanford who treats children with brain cancer and studies the disease at its source. @nationalacademies.org @nam.edu @hhmi-science.bsky.social

As a woman with a PhD & living on my own, I am every day thankful for the women who came before me. Women who fought for my ability to have a credit card, go to school, vote, make my own medical decisions, have my job, and importantly, have the choice to decide what I want my life to be.

Excellent tutorial by @jakescottmd.bsky.social substack.com/inbox/post/1...

Material Scientists, inc Prof. Fang Liu, developed a room-temperature nanoscale quantum device using molybdenum diselenide to create “twisted light” and stable quantum states - a major step toward practical, miniaturized quantum tech. Learn more: chemistry.stanford.edu/news/scienti...

First year grad students and postdocs! Get a free starter pack from New England Biolabs! www.neb.com/en-us/promot...

We’re highlighting some of the many impactful contributions from the Sarafan ChEM-H community this year. Read the thread below for our #YearInReview!

Learning a lot about bioorthogonal chemistry and clinical translation, great symposium organized by @pengwu.bsky.social and @siglecdude.bsky.social !

They posted these director level positions online with a two week deadline. These are high level positions that are typically filled through an intensive search process: canvassing and outreach, community vetting, top scientists with leadership experience. This kind of talent is not fungible.

My friend @alexchesler.bsky.social has left the NIH to become VP of Pain Research at Vertex. I am glad to welcome him to San Diego. Exciting for him and for Vertex. But NIH loses one of its superstars. Can’t help but wonder whether this government’s anti-science policies made that decision easier.

Mind blowing new preprint and Bluetorial by @krishnanyamuna.bsky.social! Shows how much we have yet to learn about cellular chemistry, the curtains get pulled back more and more with each new technology her lab invents! 👏 👏

Exciting new work from @beattylab.bsky.social and team, congratulations 👏

Nice piece on @jcstark.bsky.social’s work on antibody-lectin chimeras (AbLecs), a new type of bispecific for cancer immune therapy and more #glycotime news.mit.edu/2025/new-imm...

The 2026 Chemical Engineering Faculty Jobs List (run by Arvind Ganesan and Todd N. Whittaker) has 92 research/teaching positions and 19 teaching-only positions: docs.google.com/spreadsheets... #facultychemEjobs

Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions

If you are at #Pacifichem2025 I'll be opening the symposium of Advances in Glycan Structure and Dynamics [BIO004] at 9:15 am (sadly) from Southampton (UK) and not from Honolulu 😔, but I'll try to keep the #glycotime lively and cheerful even from afar 🤩👍

Linking the glycome and transcriptome at the single cell level #glycotime

Online now! Online now! Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies #chembiol

We are hiring a lab manager, for our research group, the Synthetic Neurobiology group (aka Boyden Lab) at MIT/HHMI (on the MIT campus, Cambridge, MA)! Please apply if you're qualified and interested, and spread the word! hhmi.wd1.myworkdayjobs.com/External/job...

Nice piece on recent article by Seyedsayamdost lab @princeton.edu published at ACS Cent. Sci. News: www.acs.org/pressroom/pr... Article: pubs.acs.org/doi/10.1021/...

Congratulations Jason Lewis!

I’m so speechless at this meaningless cruelty and disrespect for the best of our citizens who often had to QUIT TENURED JOBS to serve our country instead. Way to make us great again I guess 🤬

I love this thread by @glycoshape.org, this is @bsky.app at its best!

It's happening! Canada launched two programs to recruit international researchers. Canada Impact+ Research Chairs (1 million/yr for 8 yrs +) Canada Impact+ Emerging Leaders. I will do my best to facilitate the process for those interested. Hit me up. www.canada.ca/en/impact-pl...

Excellent story from @aniloza.bsky.social and colleague at STAT on the MOSAIC program. www.statnews.com/2025/12/08/t... 1/4

The US is funding fewer grants compared to the past. The money is given in one lump sum instead a yearly infusion from a multi-year funded grant. This leads to more competition, less $ and time to do research. Not a win-win situation. 🧪🎁🔗 www.nytimes.com/interactive/...

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏 www.biorxiv.org/content/10.6...

Letter from Congress to FDA re: undermining vaccines, page 1 of 6

I’m hiring 1-year postdoc position in computational chemistry at the University of Copenhagen The research is focusing on automated reaction prediction in collaboration with two major Pharma companies (see e.g. doi.org/10.1002/anie...) Please share #compchem

In a recent with Jan Carette’s lab, we introduce an #assembloid model for studying neuro-infection with enteroviruses including poliovirus. The videos below capture the loss of human muscle contraction, which is under the control of spinal cord neurons, after a week of infection.

“I did not resign to make a symbolic point. I resigned because staying silent would have made me complicit. I spoke up because the stakes for children, communities, and our preparedness are too high.” time.com/7338714/dr-d...

We just did some maintenance and updates to glycoshape.org, ✅ Fancy background with floating SNFG symbols 🤩 ✅ 'Latest Updates' feed from this account on bsky 🤩 ✅ Download PDB with SASA values in Re-Glyco Ensemble 🤩 Check it out!

The Office of Science and Technology Policy (OSTP) is seeking input on Federal policy updates to accelerate the American scientific enterprise. This is your chance to give some feedback on how the past ~10 months have gone for science. www.federalregister.gov/documents/20... I plan to highlight:

12 former commissioners of the FDA came together to write a Perspectives piece for the New England Journal of Medicine; raising our concerns about recent changes to vaccine approval policy at the FDA and its implications for patients and public health.

Under Trump, the NIH is giving fewer grants to fewer scientists. The grants awarded are smaller and scientists have less time to spend them. Projects in cancer, diabetes, aging, neurological disorder, and more are going unfunded. “Make America Healthy Again.”

What if “vaccines were to arrive in your mailbox in a ketchup packet and they didn't make you feel bad”? Hear from Institute Scholar Michael Fischbach @mfgrp.bsky.social on the Future of Everything podcast about possible needle-free vaccines of the future:

New York Times article on science funding with some depressing but familiar curves with interactive graphics. www.nytimes.com/interactive/...

“In the early days it was a lonely battle. Studio heads whom Taylor had made lots of money for hung up on her … Some of her friends and advisers told her to stay away from HIV and AIDS because it could end her career.” www.vanityfair.com/hollywood/20...

Remarkable story of a Georgia high school team who used CRISPR to make a rapid diagnostic test strip for Lyme disease, speeding dx from 2 weeks to days www.cbsnews.com/news/teens-m...

Congratulations on this beautiful work @scilifelab.se @stanfordmedicine.bsky.social !