Carolyn Bertozzi
@carolynbertozzi.bskyverified.social
📤 23344
📥 3224
📝 617
All views and opinions expressed are my own.
We found a new brain shuttle! Mucins on brain endothelium mediate transcytosis of cargo linked to mucin-binding “C domain”. Congratulations Sophia Shi, now a Roland Fellow
@harvard.edu
, and longtime collaborator Tony Wyss-Coray
@stanfordmedicine.bsky.social
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.03.22.713512v1
about 15 hours ago
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Fantastic new resource for glycoproteomics from
@nmriley.bsky.social
and coworkers
#glycotime
add a skeleton here at some point
about 17 hours ago
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Mariko Bennett
3 days ago
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
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Stanford Medicine
3 days ago
Walk with Me: Meet Paul Mischel, who studies how cancer cells grow, evolve, and resist treatment. His lab has uncovered key drivers of aggressive cancers. Discover what led him to this work — and his favorite comfort meal.
youtu.be/SlPd-Pdvs-k?...
@stanford-cancer.bsky.social
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Walk With Me: Paul Mischel, physician-scientist studying cancer evolution
YouTube video by Stanford Medicine
https://youtu.be/SlPd-Pdvs-k?si=UgDXj8UOkFzWEby7
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With immortal bass lines like California Girls and Good Vibrations 🙏
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2 days ago
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The 70s Guy
2 days ago
Born 24 March 1935 - Carol Kaye, one of the most prolific bass guitarists, who has played on an estimated 10,000 recordings in a career spanning over 50 years. Kaye was the bassist on many Phil Spector and Brian Wilson productions in the 1960s and 1970s. She is 91 years old today.
#CarolKaye
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Great piece on
@corsello.bsky.social
and coworkers’ exciting new discovery
@stanfordmedicine.bsky.social
add a skeleton here at some point
5 days ago
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Carolyn Bertozzi
Damon Runyon Cancer Research Foundation
5 days ago
Damon Runyon Clinical Investigator Steven M. Corsello, MD, and his colleagues at Stanford have discovered a drug that can degrade nuclear pores—the passageways by which mRNA leaves the nucleus—in cancer cells, effectively inducing cell death. Read more:
https://bit.ly/3NCJeZJ
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A hidden weakness in pancreatic cancer cells | New Discoveries
Cancer drugs often target a molecule that cancer cells rely on for survival but, crucially, healthy cells do not. When they are first identified, this type of molecule is known as a therapeutic vulner...
https://bit.ly/3NCJeZJ
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Jeremy Berg
6 days ago
Highly recommend watching
open.substack.com/live-stream/...
if you are interested in a scientific discussion of the origin of COVID-19 and some of the politics about pushing particular narratives.
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NIH FFS: The Freedom From Science Lab Leak Lecture Series
The NIH Director invited a conspiracy theorist to present his evidence-free,views on how the pandemic started. So I brought my co-conspirators to set them straight.
https://open.substack.com/live-stream/140616
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Carolyn Bertozzi
Admirable Women
7 days ago
Chemist/physician Dr. Maud Menten co-authored the seminal paper 𝘋𝘪𝘦 𝘒𝘪𝘯𝘦𝘵𝘪𝘬 𝘥𝘦𝘳 𝘐𝘯𝘷𝘦𝘳𝘵𝘪𝘯𝘸𝘪𝘳𝘬𝘶𝘯𝘨, 1931. This intro'd the Michaelis–Menten equation (image). It remains a cornerstone of
#biochemistry
, used in drug design, metabolic studies & enzyme engineering. She was born
#OTD
in 1879.
#WomenInSTEM
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Ida B Wells' Winchester Rifle
7 days ago
You could say that Rock n Roll was born 111 years ago today in Arkansas, but probably not where you'd think. Before there was a Chuck Berry or Little Richard, there was those who wanted to be like her. Rosetta Nubin better known as Sister Rosetta Tharpe, the godmother of Rock was born on this day
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Jenna Norton
7 days ago
Compare this to the sunny propaganda Jay Bhattacharya shared at Tuesday's appropriations hearing.
www.statnews.com/2026/03/19/n...
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National survey of NIH-funded researchers shows precarious state of U.S. science — ‘This is like the Titanic’
A nationwide STAT survey of NIH-funded researchers reveals that, a year after Donald Trump's return to the White House, many scientists are reeling
https://www.statnews.com/2026/03/19/nih-funding-national-researcher-survey-finds-cutbacks-disruptions/
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Jeremy Berg
7 days ago
@saveamericamvmt.bsky.social
@standupforscience.bsky.social
and
@27unihted.bsky.social
are co-sponsoring an event covering this lecture with the first NIH Freedom From Science lecture with scientists who have actually worked to find evidence and unravel the origin of COVID-19
#NIHFFS
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Jonathan Wosen
8 days ago
@statnews.com
conducted a national survey of NIH-funded researchers and found that, a year after Trump's return, many scientists are reeling, with some closing labs entirely. ‘This is like the Titanic,' one respondent told me. For full details, see our special report
www.statnews.com/2026/03/19/n...
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National survey of NIH-funded researchers shows precarious state of U.S. science — ‘This is like the Titanic’
A nationwide STAT survey of NIH-funded researchers reveals that, a year after Donald Trump's return to the White House, many scientists are reeling
https://www.statnews.com/2026/03/19/nih-funding-national-researcher-survey-finds-cutbacks-disruptions/
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Alice Ting
9 days ago
We are recruiting! If you are passionate about technology development, protein engineering, computational design, directed evolution, chemical biology - please reach out! (The setting is pretty nice too…)
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Another unbearable read but do not look away
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9 days ago
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Nature
10 days ago
A simple celebratory post about completing my PhD went viral for all the wrong reasons. Here’s how I managed the backlash and used the attention to promote my research, says Juliet Turner
go.nature.com/4sQu3uX
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How I turned online misogyny about my PhD into momentum for my career
A simple celebratory post about completing my PhD went viral for all the wrong reasons. Here’s how I managed the backlash and used the attention to promote my research.
https://go.nature.com/4sQu3uX
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“This is not efficiency. This is not streamlining. This is the systematic elimination of scientific stewardship at the world’s largest biomedical research funder.”
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11 days ago
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Note the analysis on the discordance between the health and economic burden of endometriosis vs relative federal investment in research. TL:DR, very bad.
www.owlposting.com/p/endometrio...
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Endometriosis is an incredibly interesting disease
5k words, 23 minutes reading time
https://www.owlposting.com/p/endometriosis-is-an-incredibly-interesting
12 days ago
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Julia M. Rohrer
12 days ago
"How could this not be your life goal to work on? To reduce how awful maladies, and the awful solutions to those maladies, are? What else is there really? Better prediction markets? What are we talking about?"
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Ask not why would you work in biology, but rather: why wouldn't you?
1.9k words, 9 minutes reading time
https://www.owlposting.com/p/ask-not-why-would-you-work-in-biology?hide_intro_popup=true
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Carolyn Bertozzi
Yamuna Krishnan
12 days ago
Watch. Learn.
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Joshua Weitz
12 days ago
A point of contrast.
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Another informative and thought provoking piece by
@dereklowe.bsky.social
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13 days ago
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Exciting new discovery from
@jimwellsucsf.bsky.social
and coworkers, a new class of potential cancer antigens flipped onto the cell surface via autophagy-associated exocytosis, featuring first author and former PhD student Corleone Delaveris!
#proudofalumni
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14 days ago
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Carolyn Bertozzi
Stanford Medicine
15 days ago
Meet Steven Artandi, a physician-scientist who studies cancer biology. His work helps uncover the mechanisms that enable cancer to grow and persist. Learn what he wanted to be when he was a kid — and the quote he lives by.
youtu.be/UWwT5owtCdc?...
@stanford-cancer.bsky.social
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Walk With Me: Steven Artandi, oncologist studying cancer biology and aging
YouTube video by Stanford Medicine
https://youtu.be/UWwT5owtCdc?si=kiH_npufDmr4cZh8
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Carolyn Bertozzi
Chris Ashwood
18 days ago
Pleased to share our native glycomics workflow preserving O-acetylation, detecting this labile modification in rat (53%) and mouse (9%) serum N-glycans. Integrally, O-acetyls are invisible under standard reductive conditions. Now published at Molecular Omics. Link:
academic.oup.com/molecular-om...
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Native PGC-LC–MS profiling reveals distinct O-acetylation patterns of Sialylated N-glycans across mammalian sera
Abstract. O-acetylation of sialic acids represents an additional layer of structural diversity and biological complexity, occurring at various hydroxyl pos
https://academic.oup.com/molecular-omics/advance-article/doi/10.1093/molecular-omics/aaiag010/8509913?utm_source=authortollfreelink&utm_campaign=molecular-omics&utm_medium=email&guestAccessKey=27cd0a14-d70d-4111-b935-52669dc39477
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Jeremy Berg
18 days ago
ACTION ITEM-----ACTION ITEM Because of overwhelming demand, NIH has new links for the Strategic Plan webinars March 16, 2026 12:30 - 1:30 pm |
www.scgcorp.com/strategicpla...
April 8, 2026 2:30 - 3:30 pm |
www.scgcorp.com/strategicpla...
NOTE: YOU HAVE TO RE-REGISTER IS YOU REGISTERED BEFORE
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Developing the NIH-Wide Strategic Plan for Fiscal Years 2027-2031
https://www.scgcorp.com/strategicplan2026mar/Default
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Alexandra Lahav
19 days ago
In honor of international Women's Day I am going to tell you a story about Ellen Ash Peters, the first female professor at Yale Law and the first female Justice on the Connecticut Supreme Court.
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ACS Publications
19 days ago
This International Women’s Day 2026, we celebrate the women shaping India’s scientific research landscape! Explore inspiring insights from women in science across the country, along with a curated collection of research articles published in ACS journals:
buff.ly/XBGH2NZ
#IWD2026
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Yamuna Krishnan
20 days ago
So proud of him.
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Carolyn Bertozzi
Stand Up for Science!
21 days ago
We can save science, protect health and defend this democracy, but we have to act NOW. Hit the streets! Make yourself seen and heard! Join us on the streets at rallies nationwide on March 7th! Don't sit this out.
standupforscience.net/march7
#ItsUpToUs
#standupforscience
#rally
#March7
#science
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Carolyn Bertozzi
Joe Sabatino
22 days ago
For those in the SF Bay area, please consider attending the SUFS rally this Saturday, March 7 at SF City Hall from 1-3 pm
#standupforscience
@standupforscience.bsky.social
fight2win.standupforscience.net/SF-March/
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Stand up for Science
Stand up for Science
https://fight2win.standupforscience.net/SF-March/
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Carolyn Bertozzi
Jeremy Berg
22 days ago
My weekly update on NIH funding This includes awards made through 2/27/26 Warning: This thread contains data compiled by a known deranged_activist™. Do not read while operating heavy machinery. 1/9
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BrunetLab
22 days ago
Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!! Congratulations to Paloma Navarro and the entire team! Fantastic collaboration with Chris Garcia's lab, Tony Wyss-Coray's lab, and Saul Villeda's lab!
www.cell.com/immunity/ful...
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Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
Immune cells populate the old brain, but whether they can be specifically targeted to improve brain function in older individuals remains unclear. Navarro Negredo et al. dissect how aging impacts brai...
https://www.cell.com/immunity/fulltext/S1074-7613(26)00038-5
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Carolyn Bertozzi
Jeremy Berg
23 days ago
I just tried to register. The March date is already listed as Full! I did register for the April date. You have a chance to enter questions. I don't know if there will be another opportunity to do this.
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Carolyn Bertozzi
Stanford Medicine
23 days ago
Meet Sergiu Pasca, a neuroscientist whose work explores the biological basis of brain disorders such as autism and schizophrenia. Discover a favorite “aha” moment and the place he seeks out when he’s not in the lab.
youtu.be/6QOptRJUH8k
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Walk With Me: Sergiu Pașca, neuroscientist studying early brain development
YouTube video by Stanford Medicine
https://youtu.be/6QOptRJUH8k
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Check out this cool
#glycotime
conference
@vai.org
in May 2026, co-organnized by Sharon Pitteri
@stanfordbiosci.bsky.social
alongside Ginny Shapiro, Brian Haab, and Richard Drake.
www.vai.org/event/cancer...
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Cancer Glyco-X 2026: Intersections of Cancer and Glycoscience
Join us for Cancer Glyco-X 2026: Intersections of Cancer and Glycoscience at Van Andel Institute Stay informed about exciting upcoming events and activities.
https://www.vai.org/event/cancer-glyco-x-intersections-of-cancer-and-glycoscience/
25 days ago
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Carolyn Bertozzi
Nick Riley
28 days ago
MS/MS scan range can be an afterthought that doesn't receive attention in method design, but improper settings can affect experimental outcomes. This is especially true in glycoproteomics. A
#glycotime
thread about a new
#JASMS
paper on this idea from
@riley-research.bsky.social
1/10
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Carolyn Bertozzi
Department of Chemistry, Stanford University
28 days ago
Congratulations to Grant Rotskoff and Steven Banik on being named 2026 Sloan Research Fellows - honoring outstanding early-career scientists shaping the future of chemistry and discovery! 🎉
#SloanResearchFellows
chemistry.stanford.edu/news/chemist...
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Chemistry Faculty, Banik and Rotskoff, named 2026 Sloan Research Fellows | Chemistry
The award recognizes early-career scientists whose accomplishments mark them as the next generation of leaders.Grant Rotskoff and Steven Banik are among eight Stanford faculty to receive the 2026 Sloa...
https://chemistry.stanford.edu/news/chemistry-faculty-banik-and-rotskoff-named-2026-sloan-research-fellows
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Get to know biomedical researchers
@stanfordbiosci.bsky.social
@stanfordchemistry.bsky.social
@stanford-chemh.bsky.social
through our new “walk with me” series
stanmed.stanford.edu/we-are-stanf...
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In the Walk With Me video series — walk with us as researchers tell their stories
The new “Walk With Me” video series goes behind the scenes with some of the people who teach and make discoveries and care for patients at Stanford Medicine.
https://stanmed.stanford.edu/we-are-stanford-medicine-walk-with-me-videos/
29 days ago
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Fascinating discovery by team
@stanfordbiosci.bsky.social
www.cell.com/cell/abstrac...
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Nutrient competition predicts gut microbiome restructuring under drug perturbations
Systematic profiling of 707 drugs on their impact on stool-derived microbial communities shows that nutrient competition explains and predicts species shifts under drug treatment and that post-drug re...
https://www.cell.com/cell/abstract/S0092-8674(25)01243-7
30 days ago
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Sam Barrett, PhD
30 days ago
New essay on LLMs and brain rot: "LLMs do not inevitably corrode thinking. They amplify whatever epistemic posture you bring..."
sbgeoaiphd.github.io/rotating_the...
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Amplifiers of Epistemic Posture
Essays and writing on AI
https://sbgeoaiphd.github.io/rotating_the_space/posture
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Carolyn Bertozzi
Lisa Jarvis
30 days ago
My thoughts from last spring on Surgeon General nominee Casey Means' push for continuous glucose monitoring as a way of improving metabolic health:
www.bloomberg.com/opinion/arti...
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MAHA Is Pushing Glucose Tracking That Most People Don’t Need
Surgeon General nominee Casey Means’ metabolic health theory isn’t based on the “gold-standard” science the movement promises.
https://www.bloomberg.com/opinion/articles/2025-05-17/maha-pushes-glucose-tracking-that-most-people-don-t-need?accessToken=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJzb3VyY2UiOiJTdWJzY3JpYmVyR2lmdGVkQXJ0aWNsZSIsImlhdCI6MTc3MjAzMjM1NywiZXhwIjoxNzcyNjM3MTU3LCJhcnRpY2xlSWQiOiJTV0VNT1hUMEcxS1cwMCIsImJjb25uZWN0SWQiOiJBQkE5NzNFNjA3NkQ0NjMyODJFMDAyN0QyM0JDNTg5MyJ9.txodNVaEpM6I97Lk_Pq_G3ODS1GOl5k3YlPVN8eqO3Y
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Carolyn Bertozzi
Alexis Rohou
about 1 month ago
Our department at Genentech is hiring. We're looking for a freshly-minted PhD (0-3 years) protein biochemist / structural biologist to join as a Sr Scientist. A rare opportunity to join our group leader job family at a more junior level than we usually hire.
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Senior Scientist, Protein Sciences in South San Francisco, California, United States of America | Research & Development at Genentech
Apply for Senior Scientist, Protein Sciences job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech
https://careers.gene.com/us/en/job/202602-104356/Senior-Scientist-Protein-Sciences
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Carolyn Bertozzi
about 1 month ago
A lot of those on SI...
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Carolyn Bertozzi
Jessica Stark
about 1 month ago
Great to see our work to engineer AbLecs as a new immunotherapy modality featured in
@natrevdrugdiscov.nature.com
!
www.nature.com/articles/d41...
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Antibody–lectin chimeras: new checkpoint inhibitors in the toolbox
Discover the world’s best science and medicine | Nature.com
https://www.nature.com/articles/d41573-026-00023-7
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Carolyn Bertozzi
Department of Chemistry, Stanford University
about 1 month ago
Professor Kevan Shokat (UCSF) will present a Student Hosted Colloquia on “Overcoming the Undruggable Nature of the Most Common Human Oncogene: K-Ras.” Join us today at 3PM in STLC 114. (Student Host: Kaan Tarhan)
chemistry.stanford.edu/events/stude...
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Student Hosted Colloquia: Professor Kevan Shokat, UC San Francisco | Chemistry
About the Seminar“Overcoming the Undruggable Nature of the Most Common Human Oncogene: K-Ras”Somatic mutations in the small GTPase K-Ras are responsible for approximately 30% of
https://chemistry.stanford.edu/events/student-hosted-colloquia-professor-kevan-shokat-uc-san-francisco
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Carolyn Bertozzi
Geoff Petty
about 1 month ago
www.theguardian.com/environment/...
“On climate, the hour for collective action has already arrived. The science is here. What we need now is courage – courage scaled to the enormity of the task – so we may gift the next generation not only carbon capture, but a planet worthy of their hopes,”
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‘Reimagining matter’: Nobel laureate invents machine that harvests water from dry air
Omar Yaghi’s invention uses ambient thermal energy and can generate up to 1,000 litres of clean water every day
https://www.theguardian.com/environment/2026/feb/21/nobel-laureate-omar-yaghi-invents-machine-that-harvests-water-from-dry-air?CMP=Share_iOSApp_Other
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Carolyn Bertozzi
Jeremy Berg
about 1 month ago
Deep, well sourced, moving, and enraging story from the NYT [Gift Link]
www.nytimes.com/2026/02/23/o...
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Opinion | The Human Cost of Trump’s War on Science
https://www.nytimes.com/2026/02/23/opinion/doge-hiv-funding.html?unlocked_article_code=1.OVA.5oAa.l7IKTZ3B6b0Q&smid=url-share
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