When I explain to people what is involved with writing a successful grant, they simply don’t believe me. I explained it once to a famous person from Pixar, and he looked me square in the eye and said: You mean all the cancer and Alzheimer’s grants work that way? You’ve gotta be &$%#ing kidding me!

www.fiercebiotech.com/biotech/nih-... we need more voices of concern from the biotech sector on NIH and FDA instability

Ok Lab people! I've finally joined the universe of 3D printing! Tell me your favorite/useful/best lab-based bioscience things I need to print (on a simple, single filament machine) and where to find the files!

For anyone trying to keep up with the grant termination/delay litigation against NIH, the ACLU has a good page with summaries and links. www.aclu.org/cases/apha-v...

Happy New Year folks!! Start the year off with a submission into Black In Neuro’s first ever special issue. 18 days until the deadline, keep an eye out for the release 📝 ✨ @binmanhattan.bsky.social @academic.oup.com

Science 🤝 Democracy. The Trump admin's fight against science harms our 1st Amendment rights. Flipping a complicit Congress is critical in the fight against unpatriotic anti-science, and where the Science Fight Club comes in. Find out how to join the fight here: zurl.co/fa315 #standupforscience

I don't think you non-science people realize what it takes to get a grant funded by NIH. Started experiments in Sept 2021 to generate 3 new mouse mutants to model human disease. Prelim dara shows they have relevant disease phenotypes worthy of study. Need a small grant first to characterize /1

2025 sucked. In 2026, we are taking back our science! We are excited to launch our Substack: The Science Fight Club. Read our first post, written by @cdelawalla.bsky.social, a review of 2025, a preview of 2026, and a big call to action. open.substack.com/pub/sciencef...

The final Calvin and Hobbes, which appeared in papers 30 years ago today.

High Altitude Cooking Instructions xkcd.com/3187/

1-this is really good news. 2-what’s the equivalent discovery we won’t have due to Trump, Kennedy, Vought, and Musk?

Stop. Read the post below. Do what it says. Look at Earth - our home world - from the surface of Mars. You are a terranaut on that fragile planet. This moment brought to you courtesy of NASA Science.

Copy number variants (CNV) interfere with human Accelerated Regions (HARs) to cause neurodevelopmental disorders: a large-scale cohort study https://www.biorxiv.org/content/10.64898/2025.12.29.696895v1

@sfu.ca is hiring Canada Impact+ Research Chairs. Research areas include health, including biotechnology; clean technology and resource value chains; environment, climate resilience and the Arctic; democratic and community resilience. Candidates must full Profs or Associate 2 years from promotion.

🚨 Alarm!!! 🚨 AI/ML course for microscopy image analysis!!! 🧐 In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!? 20 students, ~14 TAs and lecturers 🗓️ June 4-18 2026 ✍️ Jan 15 2026 ✍️ 🔁 pls!! www.janelia.org/you-janelia/...

A nice thread in which an actual expert patiently explains why the Secretary of Health and Human Service is not simply a liar, but an especially stupid one.

More news (not good) from NIH The renewal request from National Institute of Neurological Diseases and Stroke Director Walter Koroshetz has been denied. I guess the NIH_leadership™ needed another position to fill with their time-tested recruitment process.

As you celebrate the holidays, here are 10 things to know about the dramatic changes to how NSF does business. This story looks at merit review. The second part will explain the significance of NSF's new structure. www.science.org/content/arti...

👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇

While Bari Weiss scrambled to remove the video from YouTube, the Canadian bootleg I posted on Substack last night is still there.

here's the 60 minutes cecot video part 1 of 5 - recorded/uploaded by and all credit to @jasonparis.bsky.social I just reduced background noise, chopped the 14 minutes into 3 minute segments each compressed under 100 mb for bsky's limits, cropped and rotated a few degrees for easier viewing on here

🤔 DID YOU KNOW? The Stand Up for Science Foundation is now registered on Fidelity Charitable! This means you can make tax-deductible donations (even anon!) to SUFS...it's quick, easy, and secure. Cap off your year end giving by supporting the fight for science! @standupforscience.bsky.social

High Quality version of the 60 Minutes segment on the CECOT that was cut but has now been leaked: www.thereset.news/p/breaking-h...

My new year's resolution - relearn basic cellular biochemistry and metabolism. More and more relevant to my field. I've got to overcome PTSD of learning the Kreb's cycle in undergrad! 🧠🧪⚛️🤪

The full spiked 60 Minutes CECOT package, clean & subtitled. 1/5

WATCH: Here's the segment CBS News pulled from "60 Minutes" last night

There are AMAZING and often AMUSING stories about our information universe. Enjoy! Well worth your time

BREAKING: WATCH the full 60 Minutes CECOT segment here. This was sent to me anonymously. It appears to be the segment CBS' Bari Weiss killed. www.muellershewrote.com/p/watch-the-...

Can confirm: Pulled 60 Minutes “Inside CECOT” segment on the El Salvador mega prison housing hundreds of Venezuelan deportees sent by the U.S. is on Global TV’s free app

AI-generated/heavily influenced grad school applications were abundant this round. They felt "off" - not genuine. In my opinion, if you are applying for a position that requires extensive critical thinking and writing, using AI for your application does NOT help your case with reviewers.

Now seems like a swell time to point out that Frontline just released this excellent 11-minute mini-documentary about what happened inside CECOT.

Alright scientists! It's that time again! Time to sign up for Skype a Scientist's spring semester. Want to get matched with a classroom in 2026? Sign up now 🥰 docs.google.com/forms/d/e/1F...

I'm here to tell you that this is generational levels of damage. Generational in that it will take a generation or two to fix the damage. Some damage will be unrecoverable, and that makes us all lesser. This is not making America "great"... This is a self-inflicted wound that is mortal to many.

Oh my God it just keeps getting worse. This #RFK sponsored #hepatitis vaccine trial in #Guinea-Bissau is being run by people whose research methods have been totally discredited. This isn’t research, it’s gun-for-hire antivax nonsense. www.sciencedirect.com/science/arti...

In addition to creating chaos around issues that are not on his priority list, Director Bhattacharya appears to be incapable of delivering on issues that he claims are high priorities for him. Incompetent or dishonest (or both)? 4/4

This is a wildly unethical study that would be illegal to conduct in the United States. Have you heard of the Tuskegee experiments (crimes against humanity)? This sounds like that.

A story that should shock our collective conscience: After Trump Cuts to Kenya Food Aid, Children Died of Starvation

The world's leader in science is dismantling itself. For nothing.

Mind blowing new preprint and Bluetorial by @krishnanyamuna.bsky.social! Shows how much we have yet to learn about cellular chemistry, the curtains get pulled back more and more with each new technology her lab invents! 👏 👏

Tap tap tap. Does this work? @jenna-m-norton.bsky.social is serves the people. Not the political will. We are #scientists. #NIHStrong #imwithjenna #BethesdaDeclaration

INBOX: Former NIAID director Jeanne Marrazzo is suing the Trump administration. She alleges the NIH violated her constitutional rights and illegally fired her after she blew the whistle on actions that jeopardized public health and violated federal law.

We gave Jay Bhattacharya an opportunity to clarify his vaccine stance: does he REALLY believe that the vaccine is worse than the disease? Instead, he launched into a defense of MAHA as the future of scientific inquiry, and never really gave us a straight answer... @repauchincloss.bsky.social

Thank you @cdelawalla.bsky.social for @standupforscience.bsky.social and asking the hard questions. Thanks for all that you are doing!

We are failing our kids

Another way to restart the world’s idea machine is to restore funding and grants to universities, researchers, and artists.

A cast of Trump’s lesser-known political appointees and DOGE operatives cut programs in ways that guaranteed widespread harm and death in some of the world’s most desperate situations. From our friends at @propublica.org:

Getting a COVID Vaccine while Pregnant Slashes Risk of Premature Birth, Major New Study Finds www.scientificamerican.com/article/gett...

My official response to the doomers and naysayers: