Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n openrxiv.org/enabling-rev...

Please read the thoughtful Blog that @richardsever.bsky.social and the @openrxiv.bsky.social team wrote on integrating pre-prints with AI review openrxiv.org/enabling-rev...

And you can of course also go through to the q.e.d website: www.qedscience.com

Here's how you can go to @qedscience.bsky.social from the @openrxiv.bsky.social @biorxivpreprint.bsky.social website, when you submit a manuscript:

IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇

If you're looking for a faculty position at the intersection of ecology and computing (both broadly defined), please apply to this joint search between the CEE Department and the College of Computing at MIT: cee.mit.edu/people/share...

Visionary talk from Jennifer Lewis yesterday at the MIT.nano Dresselhaus Lecture, highlighting opportunities for 3D printing in soft robotics & tissue engineering! You can watch the full lecture and the q&a session (moderated by me!) here: mitnano.mit.edu/events/dress... @wyssinstitute.bsky.social

When ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants.

Some iocaine perhaps to jog his memory?

Interesting work profiling surface proteins from the Kossiakoff lab U Chicago. Corroborates the concept of @oawlab.bsky.social on cancer specific csU5-snRNP200 and our work on csNPM1 but here with more than 500 (!) novel Fabs and 40 antibodies developed. Very cool www.biorxiv.org/content/10.1...

Some charts for those who don't know the extent of the US public (and private) investment in research (particularly in biomedical research) compared to other countries and institutions. The destruction of the US' scientific institutions has global implications.

#InflammasomePower! 💥New paper alert💥 How is NLPR3 primed & activated in chronic non-communicable inflammatory diseases? With @oceanedufies.bsky.social &co we show that chronic exposure to oxPAPC drives NRF2 activation that primes & activates NLRP3 sustaining #atherosclerosis in mice & humans! 👇👇👇

Lab organized a pretty good costume

What a gem from @dudinlab.bsky.social @gautamdey.bsky.social @centriolelab.bsky.social in Cell! Expansion microscopy atlas of >200 eukaryotes comparing cytoskeletal architectures revealing structures not seen before. Stunning visualisation! Exactly the kind of transformative cell biology we need.

Science brings us new miracles every day. Update from a mother whose son was the first patient dosed with Grace Science's gene therapy for NGly1 deficiency (GS-100). Video can be seen on YouTube. #glycotime www.youtube.com/watch?v=tdNn...

This is heartbreaking 💔 to read. Thank you 🙏 for sharing this with us. I want to apologize to you on behalf of real Americans. It’s a painful reminder that we must keep resisting these harmful policies so we don’t lose more people like @wwenneuro.bsky.social, whom we spent over a decade training.

Science needs to be part of our day to traditions. For many years - I have continued to give Foldscope @teamfoldscope.bsky.social with the candy on Halloween. Try it out and surprise the kids with the capacity to see and discover real #microMonsters crawling on our planet. 🎃👻 #FoldscopeHalloween

Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain. www.youtube.com/watch?v=yLvO... Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out. Watch and share! 1/7

I am extremely grateful and deeply honored to be conferred the new title of Xander University Professor by @harvard.edu 🙏 🧠🧪🧬

Our study of pseudouridines in RNA was just published - it turns out that they stabilize RNA from cleavage by having much less nucleophilic 2'-OH groups: pubs.acs.org/doi/10.1021/acscentsci.5c01345

‘Change course now’: humanity has missed 1.5C climate target, says UN head

A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...

Colleague Prof. Max Konig and Johns Hopkins colleagues show that anti-9G4 precision cellular therapies provide a strategy to selectively target pathogenic B cells in lupus, while minimizing risks of infection and cytokine-related toxicities. Read more here: www.biorxiv.org/content/10.1...

A bit dense, but the important message is dead simple: We got to cite the E = mc² paper! Kidding :) The important part is that combinations of isotopes unlock 100-1000x gains in protein measurement speed. Here's how: www.biorxiv.org/content/10.1... #TeamMassSpec #Proteomics 🧪

👏 👏 👏 www.studlife.com/news/2025/10...

Working with David Walt’s lab, here is a new tool we hope to develop into a diagnostic test for TDP-43 pathology, something we desperately need in cognitive neurology. www.medrxiv.org/content/10.1...

Thanks to Autoimmunity podcast @kevinbonham.bsky.social & @woodrufflab.bsky.social for discussing our glycoRNA paper w/ @raflynn5.bsky.social @vinnieviruses.bsky.social

Did you know that there are small RNAs embedded in the plasma membrane of your cells? I didn't! But your immune system sure does! New episode of @audiommunity.org out now! 🧪 audiommunity.org/episodes/epi...

Thanks for the discussion - fun to hear how it’s read!

We used to just make more land

This study @science.org finds what appears to be the long-lost RNA subunit of C. elegans telomerase. The TERC RNA is encoded within an intron of a germline-upregulated gene, nmy-2🪱🔬🧬Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes | Science www.science.org/doi/10.1126/...

Some people think too much money is going into CO₂ removal (CDR) and more should be spent on decarbonization instead. The reality is that annual investment in CDR (~$190 million) is dwarfed by investment in renewables (~$2.1 trillion). That's over one million percent more for decarbonization.

"Beijing’s ultimate objective is to become a supplier of nuclear power to the world" www.nytimes.com/interactive/...

📣📣📣 The University of Georgia is recruiting new Assistant Professors in the fields of Structural Biology, Cancer Research, Genetics and Microbiology. Athens is a wonderful place to live and work. Come join us! www.ugajobsearch.com/postings/456...

If you wonder why doesn't Harvard use its endowment: the answer, of course, is that we do. A major source of Harvard's annual budget is the endowment investment return. For anyone seriously interested in how university endowments work, an excellent wonky reference: www.nber.org/papers/w32506

Sugar coats shield immunogenic RNA modification:A new function for RNA glycosylation

The violent beauty of stars being born in full display thanks to the JWST! 🔭 This is the region around the HOPS-108 protostar in the Orion Nebula. There are so many beautiful jets produced by baby stars tantrum 🤩 HD: flic.kr/p/2rAgnuW

😍 Boston, you are beautiful. #NoKings

Dartmouth is OUT! Thank goodness... a friend at U of A and I have been playing "Who will be the last of the 9 standing?" and it's not gonna be us!

Sugar coats shield immunogenic RNA modification:A new function for RNA glycosylation: Molecular Cell www.cell.com/molecular-ce... @raflynn5.bsky.social @vinnieviruses.bsky.social

A university that signs the “compact” is one that acknowledges its own inability to compete and succeed based talent and merit. It would signal insecurity and mediocrity to current and future students and faculty. Say no. Recruit the best people, protect their freedom and support their hard work.

1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria. www.biorxiv.org/content/10.1...

👏 👏 👏 www.thedp.com/article/2025...

The ***constructive*** nature of the feedback is my favorite part! We’ve found it a super useful tool in the lab thus far!

We are recruiting new faculty in IMES at MIT! IMES (Institute for Medical Engineering and Science) is the MIT home of the famous HST program. As faculty are also appointed in a department at MIT, we have diverse research programs, all focused on human health. faculty-searches.mit.edu/imes-search/

The Alphabet unit’s plan to expand internationally comes as it also prepares to offer driverless rides in at least half a dozen additional U.S. cities.

Brown rejected the compact! www.brown.edu/sites/defaul...

Our latest work seeks to answer a longstanding question: why is discovering new protein binders seemingly unpredictable – and can we better quantify and understand the de novo binder discover process? 1/12 www.biorxiv.org/content/10.1...

Here's the link to the system, try it! qedscience.com @qedscience.bsky.social