Breast cancer mortality dropped 58% from 1975 to 2019. Localized, early detected breast cancer has a 99% 5 year survival rate. Modern mammogram tech was developed by NASA for telescopes. Last year, RFK Jr. cancelled 87 research grants on breast cancer. www.nytimes.com/2026/03/16/u...

I mean, these are always good. But this is So Good. Nitrogen, Ammonia, and the Strait of Hormuz | Science | AAAS www.science.org/content/blog...

They made them take down the videos because they would cause "reputational damage" to people like this young man, Nathan Cavanuagh, so definitely don't post this all over the internet with the name Nathan Cavanaugh attached, or this guy might suffer reputational damage. This guy, Nathan Cavanaugh.

Holy shit. These people shouldn’t be near sharp cutlery, let alone seats of power. Mullin: “This is war.” Raju: “You concede this is war?” Mullin: “We haven’t declared war.” Reporter: “You just said it’s a war.” Mullin: *stammer

I’ve been to Busytown. I’ve seen these things in action.

Incredible. We got to "Is a pedophile island really all that bad?" five times faster than I thought.

On the unintentional comedy scale, this was 10 of 10 for me.

This style of post is literally every second thing I see on here and it’s utterly absurd. Van Hollen in particular could not be a worse target.

He really is doing all of it.

Nothing prepares you for how rapidly you accelerate between these three states #chemchat

Mary and Joseph praying over Jesus in the manger, or TWO T. REXES FIGHTING OVER A TABLE SAW? Once seen, cannot be unseen.

Drs. Matthew Meyerson and Heidi Greulich from the @broadinstitute.org sit down and discuss how they and Bayer scientists developed the first FDA-approved #CancerDrug to come from a Broad scientific discovery. 🤝 Learn more about their academic-industry alliance: https://bit.ly/4ruQNRl

Magnolia's Cafe on Rochester's deep blue Park Ave might seem like a strange place to meet Trump supporters. But over the clank of metal spoons against bowls of tomato soup, you can hear whispers that the president's friendly meeting with Mamdani may be the beginning of a pivot to the center.

Thank the @johndoench.bsky.social and Root labs for depositing these deliciously named libraries, and check out our blog post for more:

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/

First 🟦 post - my main postdoc work is out in the world! We designed a Cas12a-based genetic screen to identify host factors that contribute to infection by the tickborne pathogen Rickettsia parkeri, and stumbled across a really exciting direct interaction between host and bacterium🦠. Check it out!

Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:

ICE Agent, 7-Year-Old Both Wearing Same ‘Military Commando’ Halloween Costume

When I explain that boycotting an election over an issue has never once forced a politician to embrace that issue, I'm not "scolding people to vote." I'm explaining reality. Feel free to sit on your ass! Just don't pretend that your lazy apathy is somehow going to advance your agenda.

Enjoy car-free small business shopping, music, games, bicycling, community tabling, and more in Jamaica Plain this weekend! 📍 : Centre Street from Lamartine St. to South St. in JP ⏰: This Sunday, November 2 from 10:30 a.m. to 3 p.m. More info: boston.gov/open-streets

This is quite a hed/subhed. 1) Start with Vance. Use strong action verb. Accept the autocratic premise that the “Marines’ Might” are Vance’s to flex. 2) Mention the protest second and absurdly describe them as in the thousands 3) Treat Trump’s strong man use of the military as a partisan scuffle.

Remember, brown 13-year-olds are hardened menaces to society, but 30-something Republican Hitler afficionados in positions of power are just li’l guys.

New CRISPR libraries from the @johndoench.bsky.social and Root labs — Jacquere (human) and Julianna (mouse). A perfect pairing for your next screen. 🍷🧀 https://twp.ai/9PX2kT https://twp.ai/4irnYP

I have lived and worked in and around Chicago for 27 years and I have been assaulted less often than Sen Paul has been in his own back yard.

79. American citizen.

I'm sorry, what?

Now with comments... Lots of comments (A long thread) 1/n

The New York Times piece today about US science is terrible and wrong—in many ways. I could write a whole article about this, but as one example: “To close observers, the original crisis began well before any of this…” No. I’m a close observer of science, and this is incorrect.

After years of complaining about cancel culture, the current administration has taken it to a new and dangerous level by routinely threatening regulatory action against media companies unless they muzzle or fire reporters and commentators it doesn’t like.

After a co-host suggested that mentally ill homeless people who don't accept services offered to them should be jailed, Brian Kilmeade replied, "Or involuntary lethal injection, or something. Just kill 'em." on.nbcboston.com/JlG99ke

A deep dive into the destruction of US cancer research by @jonathanmahler.bsky.social “It’s an absolutely unmitigated disaster,” a former top official at NIH told him. “It will take decades to recover from this, if we ever do.” Gift link: nyti.ms/48iH3Cr

Optimization of a bespoke base editor to treat a severe pediatric vascular disease! 🫀🧬 Our manuscript describes: 1️⃣ Engineering a target-specific BE🧬 2⃣ A *must avoid* bystander edit that occurs with WT SpCas9 BEs! 🙅‍♂️ 3⃣ Extension of lifespan after in vivo editing! 🐁✅ www.nature.com/articles/s41...

Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...

More news breaking at Bounces about Donald Trump's visit to the US Open men's final. The US Open has sent an email to broadcasters, obtained by Bounces, ordering them to censor any reactions or protests from the crowd to Trump's appearance. Read more here: www.benrothenberg.com/p/us-open-do...

The President of the United States is threatening to go to war with an American city. This is not a joke. This is not normal. Donald Trump isn't a strongman, he's a scared man. Illinois won’t be intimidated by a wannabe dictator.

Lot of senators today expressing deep concern about the state of vaccine policy at HHS If only someone could do something about it It’s a real quandary

SEN. CASSIDY (R) : “Do you agree Trump deserves the Nobel Prize for Operation Warp speed?” RFK JR.: “Absolutely.” SEN. CASSIDY: “But you just told Senator Bennet the COVID vaccine killed more people than COVID.” RFK JR.: “….”😬 🤷🏻‍♂️

#Massachusetts authorizes pharmacies to give #Covid19 shots www.universalhub.com/2025/massach...

JFC, Atlantic Monthly. Michelle Obama wanted kids to eat healthy and exercise. She wasn't bent on destroying our federal health agencies.

This is very good news. BUT, as we saw this year when NIH was operating under a flat budget, Trump and Russell Vought can effectively destroy NIH even if Congress holds the budget flat. To stop Vought and make sure NIH can function, Congress must go much further than “no cuts to budget.” 1/

These are my patients. Kids dying of brain cancer. Kids and families desperate for treatment and hoping to find a cure through experimental therapies. Trump is dismantling science and children with brain tumor are the victims. www.nytimes.com/2025/08/28/w...

The US Administration has decided to destroy a top network for clinical trials to test new treatments for children with brain cancer. This is another atrocity that will harm Conservative and Liberal Americans, long after the politicians responsible are gone.

I miss the old brand #CDC

RKF Jr. is a dangerous man who is determined to abuse his authority to act on truly terrifying conspiracy theories and disinformation—leaving us unprepared for the next deadly pandemic and snuffing out potential cures while he’s at it. My full statement.

She was brought to the US as an 8yo, worked hard, studied, earned a scholarship, planned to become a nurse. ICE kidnapped her. Held her for 6 MONTHS in a detention facility with conditions so miserable that she finally agreed to voluntarily move to Honduras, which her family left at gunpoint.

A new report says colleges in the Pittsburgh area contribute billions to economy

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...