GRACE plasmids for mapping #CRISPR activity patterns can be found at www.addgene.org/browse/artic... Thanks for sharing!

Wish you knew how to pick a high-fidelity Cas9 to minimize off-target cleavage without having to test multiple variants in a genome-wide assay? This straightforward approach might be for you:

Every plasmid in Addgene's collection represents someone's hard work. When a researcher publishes, the community should be able to access that new tool, as a fully verified construct, without delay. Our partnership with Plasmidsaurus is how we scale that commitment as our collection grows.

Cystector plasmids now available!

We are excited for our new partnership with @plasmidsaurus.bsky.social and it shows! We had way too much fun drawing these plasmid-loving dinos 🦖 🧬

Whatever your CNS gene transfer experiment calls for — Addgene has an AAV for that. With 1,000+ in-stock preparations and 30,000+ on-demand options, the collection keeps growing with new deposits every day. Browse AAV preparations: https://twp.ai/4ixUFp

New antibody release! We've expanded our catalog of synaptic cleft antibodies with @ipiproteins.bsky.social's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:

Researchers around the world are constantly developing and sharing new tools, and getting those materials verified and into scientists' hands quickly is what drives us. That's why we've partnered with Plasmidsaurus to scale our sequencing as the collection grows. https://twp.ai/4ixUFf

Probing cancer-specific vulnerabilities? The Yeo Lab's RBP CRISPR KO In Vivo Library targets 206 RNA-binding proteins prioritized from screens in KRAS-, BRCA1-, and MYC-driven cancers. Compact size + dox-inducible Cas9 make it perfect for in vivo screens in tumor xenografts.

Find the plasmids that make these desmosomes glow here ✨👉 www.addgene.org/depositor-co...

Your favorite plasmid, saved! Use the new save feature on Addgene's site to bookmark items, organize them into custom lists, and share with others on your project 🔖

Wondering what's the difference between Halorhodopsin and Channelrhodopsin? Curious how a plant photosensor domain could power your next gene editing experiment? Check out our Optogenetics Guide to learn about these tools and more to light up your lab! 🧠💡🔬

Do you study non-model bacteria? Cultivarium has you covered with their JEROBA (Jumping Element libRaries with Broad hOst rAnge) Toolkit. Use this kit to screen different transposon configurations and find the optimal constructs for your unique bacteria 🦠 https://twp.ai/4ixKCP

Never lose track of a plasmid again! New on Addgene: Saved Lists! Save items as you browse, organize into custom lists, and share with collaborators when you're ready. https://twp.ai/4ixKBR

Whatever your CNS gene transfer experiment calls for — Addgene has an AAV for that. With 1,000+ in-stock preparations and 30,000+ on-demand options, the collection keeps growing with new deposits every day. Browse AAV preparations: https://twp.ai/4ixP6M

We love it when depositors reach such a significant milestone! 💙🔥 Thank you for your commitment to open science!

Base and prime editors represent two of the fastest growing segments of Addgene's collection, and these fields are developing fast. Many new and improving tools were presented at the Deaminet 2026 conference. Our new blog post summarizes six take-aways from the meeting:

New antibodies just dropped! @ipiproteins.bsky.social has released a new ROBO/Slit antibody family available through @addgene.org. These reagents target key axon guidance and cell migration pathways. Check them out: https://twp.ai/4ixP3p

Serotype selection can make or break tissue targeting. Our AAV Packaged on Request service is designed to help you access the AAV tools you need, with verified cargos and robust QC. Check out our tropism guide before your next experiment: https://twp.ai/4ivYS5

Talk about multitasking. Sentinel plants developed at @danforthcenter.bsky.social may one day not only grow our food, but also act as living biosensors to report on the conditions of their own fields. 🌱🌱🌱 https://twp.ai/4ivYSU

New antibody release! We've expanded our catalog of synaptic cleft antibodies with @ipiproteins.bsky.social's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:

Join us in looking back on Deaminet 2026! Addgenie @elenamimo.bsky.social attended this conference on base and prime editing and brought us back her insights, highlighting tons of new and improved tools. https://twp.ai/4ivyql #crispr

Thanks to Steve Owens, Katherine Tolley, Griffin Tighe, and Anne Mazzola for visiting Addgene on Friday! We appreciated the chance to share our work and talk about the role organizations like Addgene play in supporting science and innovation in Massachusetts.

The go-to serotype for CNS + cardiac delivery is now available through Addgene's AAV Packaged on Request service, backed by the same stringent QC standards as our in-stock viral preparations. What cargo do you need in AAV9? https://twp.ai/4ivYPv

Open Science isn’t just a values choice. It’s an economic one. We are sharing a new independent report by @technopolis-group.com on the economic benefits of #OpenScience and what drives value when research outputs are designed for reuse at scale: plos.io/4rdAxCY

🧬💡 OptoLoop: An optogenetic tool to probe the functional role of genome organization - thanks for sharing, @mdstor.bsky.social! www.addgene.org/browse/artic...

Plasmids are available now! "A universal protein ladder for standardisation of diverse FRET assays" www.addgene.org/browse/artic...

Are your houseplants crying out for help? Mine are fine, thanks. 😝 But a team at @danforthcenter.bsky.social wants crops to be able to warn their growers when something isn't right. Check out their approach (and their plasmids!) in this post:

Just released! Fluorescent Protein Libraries from the Plesa Lab. Benchmarking protein expression, developing imaging tools, fluorescent protein engineering, and more. www.addgene.org/pooled-libra...

Last week to register for the R4E webinar on designing effective posters! www.repro4everyone.org/blog/r4e-web... Thank-you to @addgene.bsky.social for sponsorship! #AcademicSky #EduSky #neuroskyence

Need an AAV that isn’t available in-stock? Choose your preferred cargo, serotype, and volume with Addgene's Packaged on Request service. Now expanded to include AAV9, with PHP.eB coming soon. https://twp.ai/4ivYPp

Talk about multitasking. Sentinel plants developed at @danforthcenter.bsky.social may one day not only grow our food, but also act as living biosensors to report on the conditions of their own fields. 🌱🌱🌱

AAV9 is now available through Addgene's Packaged on Request service. With 4,000+ eligible cargo plasmids available, what would you like packaged in AAV9 for your next experiment? Learn more: https://twp.ai/4ivYPg

Interested in making lamin B1 glow? Explore the Allen Institute's plasmids for fluorescently tagging key structural proteins in human cell lines: www.addgene.org/depositor-co...

Find #IPI's new Neurexin and Neuroligin antibodies along with extensive application data here: www.addgene.org/antibodies/p...

We’re thrilled to help the Patriarchi Lab share their new norepinephrine sensors! Find the plasmids expressing nLightG2 and nLightR2 here: www.addgene.org/browse/artic...

We’re excited to expand access to genetic engineering tools for plants, this time with a focus on the early land plant model Marchantia 🌱 Thank you to the Haseloff lab for depositing this kit with us!

Learn how to design effective posters for scientific presentations at the next R4E webinar, details here: www.repro4everyone.org/blog/r4e-web... Thank-you to @addgene.bsky.social for sponsorship! #AcademicSky #EduSky #neuroskyence

Only smiles in the tissue culture room from now on 🙂 Find the TK4 plasmids from the Wernig lab here: www.addgene.org/browse/artic...

Sharing speeds science. Thanks for depositing and trusting us with your tools!

Check out the plasmids for pIGLET, a reproducible and efficient approach to generate zebrafish transgenic lines using site-specific recombination!

Exciting new tool for the study of mitochondrial metabolism! Thank you @jdejuan-sanz.bsky.social for sharing your plasmids.

Design–build–test–learn! These plasmids from the Santos-Moreno Lab help students learn Synthetic Biology through hands-on laboratory experiments 🙌 Check them out here 👉 www.addgene.org/browse/artic...

Apparently today is "Fresh Plasmid Friday", and we love it! 🧬 Get one step closer to a homemade nuclease/Benzonase here: www.addgene.org/browse/artic... (Featuring a bonus plasmid from @carrowsm.bsky.social)

New antibodies available from our friends at IPI! Perfect for studying the mysteries of the synaptic cleft 🧠 Find them here: www.addgene.org/antibodies/p...

Find the hot-off-the-press plasmids here! www.addgene.org/browse/artic...

Hot Plasmids are here! We've got photostable mScarlet3 variants from @zhifei-fu0326.bsky.social and Pingyong Xu labs, improved genome-wide CRISPR knockout libraries from John Doench and David Root, the latest antibodies from @ipiproteins.bsky.social, and more:

AAV9 is coming soon to our Packaged on Request options! Known for its broad tropism and widely used in neuroscience + gene therapy, AAV9 gives you more flexibility to design and scale experiments. Be the first to know when it’s live — sign up for Product & Service Updates: https://twp.ai/4iwER5

Another round of Hot Plasmids, coming right up! Read the blog to learn about our new-and-improved AAV packaging plasmids, a cellular time capsule, E. coli recoded to use a single stop codon, and more!

Our #CellLineOfTheWeek is Tom20 - illuminating the powerhouse of the cell! 🧫 Our stem cell lines & plasmids are available for just the cost of shipping to reduce the barriers to scientific discovery. 📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social#CellLineOfTheWeek #OpenScience