1/2 Celebrating a double win!✨ Yesterday, at the Lund Stem Cell Center (LSCC) retreat, Ervin Ascic was awarded the Article of the Year Award with our Science paper "In vivo dendritic cell reprogramming for cancer immunotherapy" (www.science.org/doi/10.1126/...)

1/3 Call for Authors! We are currently editing a volume on Cellular Reprogramming for Immunotherapy for the Methods in Molecular Biology series (Springer Nature). This volume will steer the future of the field and is a great way to share your lab’s protocols!

We are proud to announce that Ervin Ascic successfully defended his PhD yesterday – with the special honor of Nobel Laureate James Allison as opponent! ✨ Ervin’s work makes a strong contribution, showing that in vivo dendritic cell reprogramming is paving the way toward the clinic.

📢 New in @ImmunityCP: We have mapped the transcription factor “routes” that program two dendritic cell subsets opening paths for personalized #cancer #immunotherapy. Read it here: doi.org/10.1016/j.im... Here is a summary of what we discovered 🧵: Illustration by @azuravesta.bsky.social

1/6 Congrats to Margarida Brás and Daniel Oliveira that were awarded with PhD studentships from the Foundation for Science and Technology (FCT).

1/3 Our most recent protocol paper, “Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells”, is out in JoVE! @JoVEJournal

Doubly proud! 🎉 @inesncaiado and @luisfholiveira defended their PhDs this month with a big audience of cell reprogrammers. They brilliantly discussed their great contributions to the future of the field.

1/3 Glad to share that the work of our Postdoctoral Fellow Sandhya Malla @mal71056 secured funding from the Hanseatic Life Science Research Infrastructure Consortium (HALRIC) to study the mechanisms of dendritic cell reprogramming!

1/3 Congrats to our team member Hugo Couto Moreira, who was awarded a Doctoral INPhINIT Retaining Fellowship from “la Caixa” Foundation to develop his PhD project “Reprogramming Regulatory T-cells”! @FundlaCaixa

It’s an honor to share that our lab was awarded a Clinic & Laboratory Integration Program (CLIP) grant from the Cancer Research Institute (CRI) for the project “Engineering Synthetic Tertiary Lymphoid Structures in Melanoma with Dendritic Cell Reprogramming”. @CancerResearch

1/2 The interview series "Reprogramming Stars" featured in Cellular Reprogramming, highlights the work of leaders in the field by introducing them and their science in exciting talks. @CellRepJrnl

1/2 Congrats to our PhD student @ervin_ascic for winning the best poster award in “Improving Immunity” at the 22nd #CIMT Annual Meeting, Europe's Cancer Immunotherapy Meeting, held this year in Mainz, Germany. His work was regarded as an interesting, state-of-the-art technology.

1/3 We are excited to announce that the project Repro-TIL, standing for “Breakthrough Neoantigen-specific Tumor-Infiltrating Lymphocyte Therapies Through Novel Dendritic Cell Reprogramming”, was awarded a EIC Transition grant! @EUeic

I am excited to share that I will presenting the latest advances in in vivo reprogramming for cancer immunotherapy at the Science Spotlight session during the #ISSCR2025 Annual Meeting in Hong Kong, June 11-14, 2025.

1/4 Celebrating our collaborative efforts, highlighted in the paper “RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen presenting cells”, recently published in @PNASNews.

We recently had a great get-together joining the Pereira Lab and @AsgardThx, in an Interaction Day where all members shared their paths and aspirations. What a magnificent way to share a day with our teammates! ✨

1/3 Congrats to our team member Camille Chatelain who was awarded a Marie Skłodowska-Curie Actions (MSCA) Postdoctoral Fellowship. Her project will advance a strategy for cancer therapy with tumor-reactive T cells! @MSCActions

1/2 I am proud to announce that I will join the SciLifeLab community as a Group Leader! @scilifelab is a health and environmental infrastructure that fosters a solid web of researchers collaborating within sectors such as industry and health care. Read 👇

🌟Amazing full day of great discussions, 1-year progress updates & future planning as our @Eueic pathfinder #RESYNC consortium gathered in Turin. Exciting innovations ahead as we push the boundaries of chemical reprogramming! #HorizonEurope Read more:

1/3💡If you are looking for a postdoc position in transformative translational research, join our team! We are looking for a motivated postdoc to work on RNA-mediated in vivo reprogramming of cancer cells into dendritic cells.

Excited to welcome our new postdocs to the lab! 🎉 Looking forward to exciting science, collaborations, and discoveries together. Camille Chatelain, Peng Wei, Sandhya Malla (@mal71056), Inês Lopes (@inesrlopes13) and Sandra Schwarz. Welcome aboard! 🚀

1/4 Kicking off 2025 with our most recent review paper “Transcription factor-mediated reprogramming to antigen-presenting cells”, first-authored by our brilliant @lunduniversity PhD student, @ervin_ascic.

1/2 Thrilled to share that I’ve received the Emerging Alumni Award 2025 from Imperial College London, where I earned my PhD in 2009! This award celebrates leadership, societal impact, and a pioneering spirit. /FP

To close out 2024, we completed the Portuguese Coastal Camino to Santiago de Compostela—180 km of cycling. What a ride! Wishing everyone a 2025 filled with beautiful finish lines! /FP

Our PhD student @luisfholiveira won the Forskar Grand Prix! Luís’s creativity persuaded both jury and audience. He skillfully communicated the potential of hacking the code of dendritic cells to produce versatile soldiers in a war against cancer. Congrats!

💫Great news! Congrats to @ilya_ibc & @CamilaVazquezE who were awarded grants from The Royal Physiographic Society of Lund (@Fysiografen1772). These grants speak for the success of senior members of Pereira lab in attracting competitive funding to perform our exciting research!

💫Remember our tweet about Carl, the first? We are thrilled to announce that our research published last year in Science Immunology () where we reported these findings, was recognized with the @pfizer Award for Basic Research ()!

🎉 Congratulations to @ervin_ascic, a PhD student @CellReproLab who last week received the Cilla Weigelt Award for outstanding research on molecular mechanisms in rare and undertreated diseases. His work explores gene therapy in rare diseases & cancer. Photo: Annelie Barkelund

✨Excited for #SITC24! Catch the poster presentations by @ervin_ascic titled "In vivo dendritic cell reprogramming for cancer immunotherapy" Information about the sessions below 👇 📌Join us at the @sitcancer conference at the George R. Brown Convention Center, Houston, Nov 6-10.

📢 The Pereira Lab is hiring 2 researchers with an MSc to join the Cintech project! ➡️ Join us to advance our projects at the interface of #CellReprogramming and #Cancer #Immunotherapy 📥 Apply here until 20th of November:

A heartfelt congratulations to Filipe on his formal installation as a professor! 🎉 We're proud to celebrate this achievement and look forward to future successes✨

1/4 We are thrilled to share that we were awarded with Knut and Alice Wallenberg Foundation @KAWstiftelsen Grant!🎉 The project is titled- Neoantigen Identification with Dendritic Cell Reprogramming & was supported with 35 million SEK for the next 5 years.

🚨Reminder! Join us on 10/10 at 5 pm CET for the @OpenBoxSci seminar on "Dendritic Cells: From Differentiation to Therapeutic Reprogramming" with @ervin_ascic talking about the latest publication in @ScienceMagazine. Register:

Huge congrats to Olga Zimmermannova for winning Article of the Year Award 2024 @Lund_Stem retreat for her work- Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming!🎉 A shoutout to @ervin_ascic for his great oral presentation & other lab members for their posters!

Our study in one image! It shows a cancer immunotherapy modality by reprogramming tumor cells within tumor microenvironment to dendritic cells that glow as a light bulb in the dark symbolizing the dawn of a new class of cancer treatments. Illustration by the talented @joana_gcc

1/2 Don't miss Filipe Pereira's talk at the International Cancer Immunotherapy Conference #CICON24 Session (17:15-18:15)- What’s on the Horizon: New Tools, Technologies, and Approaches in Cancer Immunotherapy.

1/23 We are excited to announce that our most recent study “In vivo dendritic cell reprogramming for cancer immunotherapy” was published in @ScienceMagazine. Here is a summary of what we discovered!

Don't miss the #ISSCRDigital webinar on Sept 10, featuring the #ISSCR2024 Poster Award Winners! 🏆 Learn more about dendritic cell diversity in @luisfholiveira 's presentation!

Way to go @AbigailRAltman ! Stay tuned for our talks @ISEHSociety /FP

Come and listen to our great PhD student @nejcarh on the RNA-mediated reprogramming!

✨Excited for #ISEH2024! Don't miss the oral and poster presentations by @AbigailRAltman and Filipe. Information about the presentations in the flyer below👇 📌 Join us at the @ISEHSociety Conference at the Sheraton Grand, Chicago to explore groundbreaking research!

📢 Missed the first deadline? No worries! You can still apply to the second stage for our next-gen cell & gene therapy position @lunduniversity. Join us in in-vivo dendritic cell reprogramming-based #immunotherapy. Apply now: #ATMP #reprogramming

Sharing this great highlight from @ISSCR on Filipe Pereira (@CellReproLab) and his incredible work in immunotherapy. Check it out! 👉 #StemCells #Immunotherapy

1/8 Big congrats to @Mariana_Gadelho and Beatriz Vaz that were awarded with PhD studentships from the Foundation for Science and Technology (FCT) @fct_pt. Both projects will contribute to advance reprogramming-inspired #immunotherapies!

📢Reminder! Last days to apply... Don't miss your chance to become an expert in next-gen cell & gene therapy. Join us @lunduniversity for in-vivo dendritic cell reprogramming-based #immunotherapy. Apply/ask questions by 31/07:

🎉 Congratulations to @luisfholiveira, PhD student in the lab, for the #ISSCR2024 Exceptional Scientific Poster Presentation Award! His poster “Transcription Factor Blueprints Underlying #Dendritic Cell Diversity” was selected amongst over 1400! #Immunity #Reprogramming

6/7 What is exciting in this study? We demonstrated that cDC1 reprogramming in situ can be a novel immunotherapy – an off-the-shelf approach with a personalized character, paving the way for first-in-human clinical trials.

🌟1/7 Check out our new pre-print “A cancer #immunotherapy modality based on dendritic cell #reprogramming in vivo”, where we reprogram #tumor cells in situ to efficiently present antigens as type 1 conventional dendritic cells (cDC1s). How effective is it?

Congratulations to @luisfholiveira and @halitzki , PhD students in the lab for the merit abstract awards at #ISSCR2024! Meet them to discuss the mechanisms underlying dendritic cell reprogramming and diversification! Well deserved! /FP

We are excited to announce we were awarded our third ERC grant! The ERC Proof of Concept grant #DART stands for “Driving Tumor Antigen Presentation by RNA-mediated Transdifferentiation.” #ERCPoC