Institute for Protein Innovation
@ipiproteins.bsky.social
📤 322
📥 279
📝 309
We advance protein science to accelerate research & improve human health | proteininnovation.org
New axon guidance antibody alert 🧪 ➕ Anti-#SEMA6A/7A ➕ Anti-#NRP1 IPI recombinant monoclonals are designed to be mouse- and human-reactive, non-cross-reactive with other protein family members and IPI-validated for flow cytometry and immunofluorescence. View the datasheets:
buff.ly/G35AqDh
1 day ago
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Less than one month left to register for IPI’s Automated Liquid Handling course 🔔 This course is designed by IPI’s automation team to provide students, researchers, and lab personnel at all levels with support and hands-on skills for developing large-scale assays. Grab your spot:
buff.ly/pnh3UtQ
2 days ago
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Meet
#AlloyScholar
Shelby Harris! Shelby, a
@vanderbilt.edu
PhD student, joined our 2026 Yeast Display course to learn
#Abengineering
methods to study G6P's role in
#glucoseproduction
. Thanks Alloy Therapeutics for supporting this year’s Scholars! Get IPI updates:
buff.ly/a7XyBij
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3 days ago
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Just out
@cellpress.bsky.social
! Led by Deepash Kothiwal & co-authored by 20+ IPI lab members, the paper reports a novel framework to streamline antibody development, generate ML-compatible datasets and identify functional binders missed by experimental selection. Read the paper:
buff.ly/Qq5OnMu
4 days ago
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Looking for a dependable
#isotypecontrol
antibody? Our
#MOPC-21
recombinant rabbit IgG is compatible with all IPI rabbit IgG antibodies and, as a consistent non-binder, supports accurate assessment of family-wide cross-reactivity. Order now:
buff.ly/gU0M1ZE
5 days ago
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#AlloyScholar
Lorenzo Agostini (NIH) joined IPI’s
#YeastDisplay
course this month to learn cutting-edge antibody discovery and engineering techniques alongside fellow translational researchers. Thanks, Alloy Therapeutics, for the support! Get IPI education updates:
buff.ly/a7XyBij
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8 days ago
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IPI platform director André Teixeira walked through the architecture of IPI’s platform, built to combine
#yeastsurfacedisplay
,
#labautomation
and
#AI-guided
clone triage toward faster
#antibodydiscovery
. Listen to the full talk
@milaboratories.bsky.social
➡️
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End-to-End Antibody Discovery: Yeast Display, Automation, AI, and Multispecifics
Our High-Affinity Talks features Andre Texeira from the Institute for Protein Innovation. Most of the human surfaceome and secretome still lack monoclonals validated for anything beyond western…
https://buff.ly/DttUALf
9 days ago
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Scale-up and automate your workflows! Join us for a two-day interactive course, happening July 23-24. Register now:
buff.ly/GWBG1yq
11 days ago
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Deb Moshinsky, IPI characterization and validation director, will speak on a panel at Reproducibility in Science: Elevating Standards to Strengthen Research next week! Join her at Hood College on June 17! More info:
bit.ly/4au4hVM
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Reproducibility in Science 2026 | Frederick National Laboratory
Join us for the 2026 edition of the Hood College – Frederick National Laboratory Life Sciences Symposium, which showcases topics in life sciences with an interdisciplinary focus.
https://bit.ly/4au4hVM
12 days ago
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Last week’s course was a big success, thanks to our guest speakers! Dane Wittrup
@mitkochinstitute.bsky.social
, Surge Biswas at Nabla Bio & Justin Peruzzi
@aiproteins.com
shared insights on yeast display, AI Ab design & miniprotein discovery. Sign up for future course updates ➡️
buff.ly/tTcDWZk
15 days ago
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We needed a reliable recombinant rabbit IgG
#isotypecontrol—so
we built one. Designed as a consistent non-binder, IPI-MOPC21 helps assess family-wide
#crossreactivity
with confidence. And it’s now available as part of our basic protein tool collections:
buff.ly/gU0M1ZE
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Control Antibody Collection
Epitope tag antibodies to detect V5-, His-, biotin-, GC4N, EE-, ProC-, Flag-, etc., validated for western blot. Buy with Addgene!
https://buff.ly/gU0M1ZE
18 days ago
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Researchers at IPI and Alloy Therapeutics are hoping AI advances will help make drug discovery less expensive, faster and better — especially when it comes to nanobody therapeutics. Read more:
buff.ly/8ZBqnYs
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19 days ago
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It’s the last day of a great week training on
#antibodydiscovery
techniques, practicing cell sorts, and learning all about the utility of yeast display! Thanks to Sony Biotechnology the support & sharing
#flowcytometry/#cellsorting
insights! Get IPI ed pdates:
buff.ly/ZKR3alr
22 days ago
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Another day of
#yeastdisplay
! Today, students learned
#antigenbiotinylation
,
#FACS
, and
#AIproteindesign
. Thanks to today’s sponsor, Alloy Therapeutics, for sharing more on
#antibodydiscovery
via mammalian cell-based directed evolution! News on courses and events:
buff.ly/ZKR3alr
24 days ago
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Our
#yeastdisplay
course is off to a great start with an intro to the basics of
#displaytechnology
,
#librarycreation
&
#cellsorting
. Thank you to sponsor
@twistbioscience.com
& Steven Thomas for offering strategies to build effective/diverse libraries! Find out about future courses:
buff.ly/ZKR3alr
25 days ago
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New antibody alert 🧪 ➕ Anti-#SEMA3A/C/D/E/F ➕ Anti-#NRP2 ➕ Anti-#CNTN2 (TAG-1) IPI
#recombinantmonoclonals
are designed to be mouse/human reactive, do not cross-react w/other protein family members & are IPI-validated for
#flowcytometry
/
#immunofluorescence
. View the datasheets:
buff.ly/7SE9WnB
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Axon Guidance Antibody Collection
For neurons to communicate, their axons must navigate precisely to their targets through a complex process known as axon guidance or neuronal migration. This pr
https://buff.ly/7SE9WnB
26 days ago
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Still thinking about the conversations & energy from last week at the Forbes
#America250
Expo! It was inspiring to connect with so many people, share more about IPI's role in
#basicresearch
&
#drugdiscovery
, and celebrate the many achievements of our founder
@timothyspringer.bsky.social
!
29 days ago
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Join us in Boston this July for an intensive, hands-on training led by IPI’s automation team & sponsored by SPT Labtech. Register to learn the basics of
#liquidhandling
,
#methoddevelopment
and
#automation
for
#antibodydiscovery
➡️
buff.ly/3f3vP8Y
📅 July 23–24, 2026 📍 Boston, MA 👥 Only 5 spots left
about 1 month ago
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#VHHs
(#nanobodies) are powerful—but their “camel-ness” makes
#humanization
and
#optimization
challenging. IPI and Alloy Therapeutics are tackling this with a fine-tuned
#yeastdisplay
platform that can bypass frustrating traps. Read more:
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VHHs: The new kids on the therapeutic block
A ntibodies have outgrown their origins. Prodded by protein engineers, they’ve evolved into flexible molecules with myriad formats, from fragments and
https://buff.ly/PA3DHk7
about 1 month ago
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Spend two days with IPI automation experts this summer 🤝 Start automating workflows in your lab Sign up for our “Introduction to Automated Liquid Handling” course, happening right here in Boston July 23-24, 2026. Sign up now:
buff.ly/viOaakH
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about 1 month ago
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It's been a busy week! Our team flooded
#PEGSBoston
with posters and a lab automation short course, presented at
@canacn.bsky.social
's Montréal meeting alongside
@addgene.bsky.social
& made a special appearance at
#Forbes250
in SF! Great to connect with collaborators and share our science!
about 1 month ago
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Scale-up and automate your workflows with IPI’s interactive course, July 23-24, featuring: Lectures + Q&As with IPI experts A tour of automated systems for protein science Robots + method development skills A lunch + learn from our sponsor, SPT Labtech Register now:
buff.ly/MR3iVXI
about 1 month ago
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Catch IPI team & our founder
@timothyspringer.bsky.social
at the
@forbes.com
America Innovates Expo this weekend! Swing by our booth to: 🤖 Watch robots in action 🧬 Check out our antibody cartoons 💬 Chat with scientists who love what they do Tickets are still up for grabs 👉
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America Innovates - Forbes Connect
May 16–18, 2026, in San Francisco, CA — America250 and Forbes are co-hosting America Innovates. The event is a free, open-to-the-public, family-friendly, three-day experience featuring an immersive…
https://buff.ly/2WTLN2y
about 1 month ago
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What’s a VHH? Think of it like a tiny Lego-like antibody with untapped therapeutic potential. Learn more about how IPI and Alloy Therapeutics are partnering to put them to use:
buff.ly/pfaRBaa
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about 1 month ago
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Need help automating workflows in your lab? IPI’s automation team is running a hands-on course July 23-24 on the core principles w/ a tour of
#labautomation
systems for
#proteinscience
workflows & roundtable discussions on automating from scratch. Learn more and register:
buff.ly/ZclonG9
about 2 months ago
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Find IPI at
#PEGSBoston
next week! We’re running a short course on automated liquid handling, are giving talks on quantitative characterization and codon optimization, and have posters on discovery campaigns & methods. Find all the details!
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PEGS Boston - Protein & Antibody Engineering Summit | May 11-15, 2026 | Boston, MA
The PEGS Boston Summit is where the future of biologics takes shape. For over 20 years, PEGS is the go-to event for protein and antibody engineering, drug development, immunotherapy, radiotherapy,…
https://buff.ly/9ULxVp6
about 2 months ago
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Alloy Therapeutics and IPI are putting our heads together to power next-generation antibody discovery. Thanks for sharing the details, André Teixeira and Nikolai Suslov! Read more:
buff.ly/zllPJqr
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about 2 months ago
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Join us in person this July to learn the principles of
#automatedliquidhandling
, gain hands-on liquid handler
#robot
experience, develop methods with
#Python
, and get expert advice on how to build and optimize automation for
#laboratorypipelines
. Register now, spots are limited ➡️
buff.ly/qo7fcD2
about 2 months ago
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IPI is heading to SF for the
@forbes.com
America Innovates Expo in celebration of our founder
@timothyspringer.bsky.social
(
@springerlab.bsky.social
), named one of Forbes’ 250 Great American Innovators. Stop by our booth May 16–18 at the Gateway Pavilion. Free tickets:
buff.ly/2WTLN2y
about 2 months ago
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IPI is excited to partner with Alloy Therapeutics to advance next-gen antibody discovery! Our team created two synthetic humanized VHH libraries designed for stability, developability, and versatility—helping accelerate therapeutic timelines. 🔗Learn more:
buff.ly/W34tUx8
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VHHs: The new kids on the therapeutic block
A ntibodies have outgrown their origins. Prodded by protein engineers, they’ve evolved into flexible molecules with myriad formats, from fragments and
https://buff.ly/W34tUx8
about 2 months ago
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Looking for integrin antibodies? With the recent addition of Anti-Integrin beta 1 [IPI-TS2/16] and Anti-Integrin beta 2 [IPI-TS1/18], our Integrin Antibody Collection now comprises nearly 30 antibodies! View the collection:
buff.ly/a52As0G
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Integrin Antibody Collection
Highly specific recombinant integrin antibodies, validated for Flow cytometry applications. Buy with Addgene!
https://buff.ly/a52As0G
about 2 months ago
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Organisms have distinct preferences in the
#codons
used to translate DNA into
#aminoacids
. Biologists typically match a model’s bias to keep its
#translational
machinery working smoothly. But new research from IPI suggests things may be a little more complicated—or more simple ➡️
buff.ly/QqIb53c
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Codon optimization ‘bake-off’ suggests native constructs are best tool for mammalian protein expression
In the world of protein production, codon optimization is generally considered the go-to method to enhance expression and increase yields. Swapping native
https://buff.ly/QqIb53c
about 2 months ago
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Build in-demand
#labautomation
skills with IPI. Join our 2-day, hands-on course this July in Boston—now open to the broader scientific community. Learn from IPI experts designing real-world systems for
#antibodyproduction
and
#antibodydiscovery
. 8 spots available. Register now:
buff.ly/SXchNgO
about 2 months ago
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IPI is building new antibodies to label
#glialcellstates
at the
#protein
level. Our Friday workshop brought researchers together to discuss: How can protein markers assist in glia state identifications? Which
#antibodies
would be most impactful for the community? Which targets are most critical?
2 months ago
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We had a great two days with Just A Start Biotechnology Careers Program alumni! Thanks to all who joined us for a hands-on course on lab automation, liquid handling and assay design basics 🥼 🧪
2 months ago
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Congratulations to our 2026 Alloy Scholars, Shelby Harris & Lorenzo Agostini! Sponsored by our partner, Alloy Therapeutics, these exceptional scientists will have the opportunity to gain hands-on training in our June Yeast Display course & bring this knowledge back to their labs.
2 months ago
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IPI is excited to announce that we’ve opened our course in laboratory automation to the scientific community! Register to learn the basics of liquid handling, method development and automation for antibody discovery ➡️
buff.ly/vs162WJ
📅 July 23–24, 2026 📍 Boston, MA 👥 Only 8 spots available
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2026 Introduction to Automated Liquid Handling
A two-day course on automated liquid handling techniques for the life sciences.
https://buff.ly/oEOdhXD
2 months ago
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More than 50 researchers joined us yesterday for our
#adhesionGPCR
targets workshop! Thanks to all who participated to help us prioritize targets & design purpose-built
#Abs
. Interested in joining future workshops on
#glialcellphenotyping
&
#synapticcleftsignaling
? Get updates ➡️
buff.ly/9uAso7K
2 months ago
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New integrin antibodies targeting integrin beta 1 and beta 2 just joined the IPI collections 🧪 These recombinant monoclonals recognize human targets, do not cross-react with other protein family members and are recommended for flow cytometry. Order now:
buff.ly/VpcxzlC
2 months ago
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We’re excited to welcome alumni from Just A Start’s Biotechnology Careers Program to a 2-day automation course next week, made possible through support from the Mass Life Sciences Center Pathmaker program! More soon 🔬 Sign up for updates on future courses ⬇️
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IPI Events & Programs Newsletter
Sign up to receive news and updates on IPI educational events and programs.
https://buff.ly/kVjWSYe
2 months ago
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Stanford researcher Stephen Quake imagines IPI as a modern-day Library of Alexandria, preserving and activating protein knowledge to influence how a whole new generation of therapies will be made. That’s why he’s joined forces as part of our Board of Directors. Learn more:
buff.ly/PmIpnht
2 months ago
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#Robo3
antibodies are crucial for detecting the Roundabout Guidance Receptor 3 protein & studying neuraldevelopment &
#axonnavigation—but
reliable
#antibodies
are in short supply. IPI just released two anti-ROBO3s that might help. Dive into the data on our product pages ➡️
buff.ly/kk4fLJJ
3 months ago
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In a recent study, the IPI team tested 5 codon optimization schemes (including
#NativeCodons
) in the construction/expression of 18 neurologically relevant human & murine
#glycoproteins
. See which yielded the most proteins ➡️
buff.ly/TaFaWkY
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Codon optimization ‘bake-off’ suggests native constructs are best tool for mammalian protein expression
In the world of protein production, codon optimization is generally considered the go-to method to enhance expression and increase yields. Swapping native
https://buff.ly/TaFaWkY
3 months ago
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0
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There’s a lot of hype around
#AI
&
#proteindesign
, but there are some important considerations—including how these molecules perform in laboratory conditions, says IPI's platform director André Teixeira. Read more from Teixeira in this Science Arena article ➡️
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Design de proteínas: como cientistas estão criando moléculas sob medida para enfrentar grandes desafios | Science Arena
A partir de modelos computacionais e IA, cientistas desenvolvem proteínas para enfrentar desafios científicos e tecnológicos
https://buff.ly/nNQmSqb
3 months ago
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This former HHMI investigator and CZI leader was determined to keep exploring life’s smallest pieces in pursuit of large-scale scientific impact. So he’s returned to his Stanford lab and joined an effort to advance protein science. Read his story:
buff.ly/ciTChrs
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His next big idea might emerge from something small: Stephen Quake joins IPI Board
Biophysicist Stephen Quake has held many titles. He’s invented devices, developed diagnostics and launched companies. He’s won dozens of prizes and been
https://buff.ly/ciTChrs
3 months ago
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New
#Robo
#Slit
antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric
#recombinantproteins
are specific to human and mouse targets and do not cross-react with other family members.
#axonguidance
#neuronalmigration
buff.ly/mtViWPa
3 months ago
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📣LAST CHANCE! Applications for our 2026 yeast display course are due TODAY 📣 Come learn the basics of
#yeastdisplaylibrary
prep, MACS & FACS sorts, and
#AI-enabled
discovery in just 5 days — directly from yeast display leaders and working scientists. Apply now!
buff.ly/4Y5YvwK
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2026 Yeast Display Technology for Antibody Discovery
A five-day course in June 2026 combining lectures and hands-on laboratory sections to train participants in the core principles of yeast display technology.
https://buff.ly/4Y5YvwK
3 months ago
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Don't have a favorite part of
#antibodydiscovery
? Maybe you'll find it in our 5 day
#yeastdisplay
course this summer! Apply now — applications close March 30th ⏲️
buff.ly/oBlGknl
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3 months ago
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reposted by
Institute for Protein Innovation
Addgene
3 months ago
New antibody release! We've expanded our catalog of synaptic cleft antibodies with
@ipiproteins.bsky.social
's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:
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Addgene: IPI Antibody Collection
Find unique recombinant antibodies targeting families of cell surface and secreted proteins from a collaboration between Addgene and IPI.
https://twp.ai/4ixUFw
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Exciting update: Alloy Therapeutics will be funding two scholarships to attend IPI's 5 day course on yeast display technology for antibody discovery! The course is open to postdocs, students, faculty & industry scientists. Scholarships will go to top candidates who apply by 3/30 ⏰
buff.ly/av8zOGo
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2026 Yeast Display Technology for Antibody Discovery
A five-day course in June 2026 combining lectures and hands-on laboratory sections to train participants in the core principles of yeast display technology.
https://buff.ly/2VaieOG
3 months ago
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