IPI is building new antibodies to label #glialcellstates at the #protein level. Our Friday workshop brought researchers together to discuss: How can protein markers assist in glia state identifications? Which #antibodies would be most impactful for the community? Which targets are most critical?

We had a great two days with Just A Start Biotechnology Careers Program alumni! Thanks to all who joined us for a hands-on course on lab automation, liquid handling and assay design basics 🥼 🧪

Congratulations to our 2026 Alloy Scholars, Shelby Harris & Lorenzo Agostini! Sponsored by our partner, Alloy Therapeutics, these exceptional scientists will have the opportunity to gain hands-on training in our June Yeast Display course & bring this knowledge back to their labs.

IPI is excited to announce that we’ve opened our course in laboratory automation to the scientific community! Register to learn the basics of liquid handling, method development and automation for antibody discovery ➡️ buff.ly/vs162WJ 📅 July 23–24, 2026 📍 Boston, MA 👥 Only 8 spots available

More than 50 researchers joined us yesterday for our #adhesionGPCR targets workshop! Thanks to all who participated to help us prioritize targets & design purpose-built #Abs. Interested in joining future workshops on #glialcellphenotyping & #synapticcleftsignaling? Get updates ➡️ buff.ly/9uAso7K

New integrin antibodies targeting integrin beta 1 and beta 2 just joined the IPI collections 🧪 These recombinant monoclonals recognize human targets, do not cross-react with other protein family members and are recommended for flow cytometry. Order now: buff.ly/VpcxzlC

We’re excited to welcome alumni from Just A Start’s Biotechnology Careers Program to a 2-day automation course next week, made possible through support from the Mass Life Sciences Center Pathmaker program! More soon 🔬 Sign up for updates on future courses ⬇️

Stanford researcher Stephen Quake imagines IPI as a modern-day Library of Alexandria, preserving and activating protein knowledge to influence how a whole new generation of therapies will be made. That’s why he’s joined forces as part of our Board of Directors. Learn more: buff.ly/PmIpnht

#Robo3 antibodies are crucial for detecting the Roundabout Guidance Receptor 3 protein & studying neuraldevelopment & #axonnavigation—but reliable #antibodies are in short supply. IPI just released two anti-ROBO3s that might help. Dive into the data on our product pages ➡️ buff.ly/kk4fLJJ

In a recent study, the IPI team tested 5 codon optimization schemes (including #NativeCodons) in the construction/expression of 18 neurologically relevant human & murine #glycoproteins. See which yielded the most proteins ➡️ buff.ly/TaFaWkY

There’s a lot of hype around #AI & #proteindesign, but there are some important considerations—including how these molecules perform in laboratory conditions, says IPI's platform director André Teixeira. Read more from Teixeira in this Science Arena article ➡️

This former HHMI investigator and CZI leader was determined to keep exploring life’s smallest pieces in pursuit of large-scale scientific impact. So he’s returned to his Stanford lab and joined an effort to advance protein science. Read his story: buff.ly/ciTChrs

New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members. #axonguidance #neuronalmigration buff.ly/mtViWPa

📣LAST CHANCE! Applications for our 2026 yeast display course are due TODAY 📣 Come learn the basics of #yeastdisplaylibrary prep, MACS & FACS sorts, and #AI-enabled discovery in just 5 days — directly from yeast display leaders and working scientists. Apply now! buff.ly/4Y5YvwK

Don't have a favorite part of #antibodydiscovery? Maybe you'll find it in our 5 day #yeastdisplay course this summer! Apply now — applications close March 30th ⏲️ buff.ly/oBlGknl

New antibody release! We've expanded our catalog of synaptic cleft antibodies with @ipiproteins.bsky.social's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:

Exciting update: Alloy Therapeutics will be funding two scholarships to attend IPI's 5 day course on yeast display technology for antibody discovery! The course is open to postdocs, students, faculty & industry scientists. Scholarships will go to top candidates who apply by 3/30 ⏰ buff.ly/av8zOGo

Our automation team is running a #PEGSBoston short course on May 12 for scientists looking to gain skills in automated liquid handling and see integrated systems for protein & antibody engineering in action. Early bird registration ends March 27th & spots are limited. Check it out! buff.ly/MHgLfXV

💫Preprint alert 💫 A new IPI study suggests scientists may be overestimating the value of #codonoptimization when producing #mammalianproteins in mammalian cell lines, throwing the value of these strategies into question. Read more: buff.ly/1vUqbTj

⚠️ ONE WEEK to apply for our yeast display course ⚠️ Join us in June to get experience designing yeast display libraries, running #MACS/#FACS sorts & discovering top antibody candidates. Apply now: buff.ly/7rqgQWz Thanks to our sponsors Alloy Therapeutics, @twistbioscience.com & Sony Biotechnology!

Learn the ins and outs of yeast display discovery, from antigen biotinylation to antibody identification, in our 5 day summer course. Apply by March 30th! buff.ly/1pWSBdO

Our course on automated liquid handling for protein/antibody engineering is coming to #PEGSBoston on May 12, 2026. Participants will develop methods on the Opentrons Protocol Designer, operate an OT-2 & Biomek i3 and tour the IPI lab. Spots are limited — find out more & register: buff.ly/MHgLfXV

Interested in learning the basics of #yeastdisplaytechnology and #antibodydiscovery from leaders in the field? Join us in June for our hands-on 5-day course. Spots are limited — apply now: buff.ly/zrnlPN7

This article @thetransmitter.bsky.social shows just how vital labeling tools (like IPI’s epitope tag antibodies) can be in determining the functional identity of brain cells. Read the piece: buff.ly/Vcsim6J Check out our protein tools: buff.ly/SzcrTp1

Find new IPI ROBO/Slit antibodies in the @addgene.bsky.social catalog!

New antibody release! 🧪 Anti-ROBO1 [IPI-ROBO1.81] 🧪 Anti-ROBO3 [IPI-ROBO3.119] 🧪 Anti-ROBO3 [IPI-ROBO3.124] 🧪 Anti-Slit-2 [IPI-Slit2.37] Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more buff.ly/oNye2Ky

"Antibody discovery is like a race," says IPI research associate Swethika Balasankar. Learn how to run your own discovery campaigns using #yeastdisplaytechnology at our hands-on course this June. Apply by March 30th! buff.ly/92wAFCo

"AI isn't smart enough to provide the ultimate solution to a problem, but it's very good at finding alternative solutions," says André Teixeira, senior director of the IPI #antibody platform. Read more from Teixeira and others in this Science Arena rundown on #AI and #proteindesign.

Apply now for our 2026 Yeast Display Technology for Antibody Discovery course! buff.ly/KuyAKw3 Highlights include: ▪️ Lab sessions on library prep, biotinylation, MACS & FACS ▪️ Lectures on principles, applications and methods of yeast display ▪️ Seminars from invited experts on display technology

IPI welcomes Stanford biophysicist Stephen Quake to our Board of Directors! He brings a wealth of experience with HHMI, CZI and more, and his unique perspective will be instrumental in launching the next era of protein science. Read more: buff.ly/9coNPo2

A team at Seoul National University (@martinsteinegger.bsky.social) recently introduced FoldMason @science.org—an open-source tool to compare MSTA of 1000s of proteins. We see big potential to analyze proteins w/ conserved structure & limited sequence conservation

Scientific progress is built on shared knowledge, accessible learning, and hands-on training. So this June we’re teaching a 5 day immersive course on the #yeastdisplay principles, applications and practical workflows that drive our #antibodydiscovery campaigns. Apply by March 30 ⬇️ buff.ly/n8crLD0

Is it only March? It’s been a busy year so far! We kicked off the year hosting a lab automation course with HMS MEDscienceWorks at Emmanuel College.

One month left to apply to our hands-on #yeastdisplay course! Learn more ➡️ buff.ly/XpRYLOC

New Neurexin and Neuroligin antibodies just joined our Synaptic Cleft Antibody Collection, available through @addgene.bsky.social: 🔹 IPI-NRXN1α 🔹 IPI-NRXN2α 🔹 IPI-NRXN3α 🔹 IPI-NLGN2 🔹 IPI-NLGN3 View more data ➡️ buff.ly/YYL1WWE

A new @pnas.org study caught the eye of our bioinformatics team with its identification of ~4,500 targetable binding sites & binding seeds across human cell surface proteins—giving IPI and other labs a protein design launch point.

Applications for our 2026 Yeast Display Technology for Antibody Discovery course are due on March 30th. Here’s what you need to know! Apply now! buff.ly/lag7LwW

Attending #SLAS2026 earlier this month was incredibly valuable for our Automation and Education teams as we think about how to build new resources for lab automation training. Here are a few of our biggest takeaways:

New #Neurexin and #Neuroligin antibodies just joined our Synaptic Cleft Antibody Collection today, available through @addgene.bsky.social — 🔹 IPI-NRXN1α 🔹 IPI-NRXN2α 🔹 IPI-NRXN3α 🔹 IPI-NLGN2 🔹 IPI-NLGN3 buff.ly/YYL1WWE

What does antibody discovery mean at IPI? It means using FACS and MACS to winnow a vast yeast synthetic library, with 10^10 unique sequences, down to just a few highly selective, tight-binding antibodies that hold potential as research reagents and therapeutics.

Our director of automation, Curtis Walton, joined Opentrons on their Designing Open Science podcast last week. Listen to learn about IPI’s scalable, automated systems that support IPI scientists at the bench!

Axon guidance shapes how #neurons connect—and proteins like #Netrin-1, #DCC and #PUNC sit at the center of this process 🧠 IPI now offers #recombinantantibodies to all three targets, backed by solid validation data. Explore our reagents: buff.ly/T1CktaD

IPI’s #yeastdisplay course is back by popular demand! Join us in June to learn the basics & hear directly from experts Dane Wittrup (@mitkochinstitute.bsky.social), @surgebiswas.bsky.social (Nabla Bio) & Justin Peruzzi (@aiproteins.com). Applications are due on March 30! buff.ly/KmY7N86

We kicked off #SLAS2026 (@slasorg.bsky.social) by teaching a short course on automated liquid handling to some wonderful, engaged scientists and presenting our approaches to purification and integrated lab systems. Still time to find us to share strategies, approaches, hot-takes, etc!

Hello from #SLAS2026 (@slasorg.bsky.social)! We shared automation tips as part of a liquid handling short course today, and we're excited to connect all week. Come find us! 👉 Feb 9-11: Posters on characterization, purification, integrated systems & more 👉 Feb 11: IPI talks automation ed w/ Opentrons

We’re bringing our five-day yeast display course back for 2026! Last summer, 12 researchers from around the world joined IPI to learn the principles, applications and methods of #yeastdisplaytechnology — this year it could be you! Apply to join us this June: buff.ly/IOLmxV2

Applications for IPI’s 2026 Yeast Display Technology for Antibody Discovery course are now open! Join us for 5 days this June to learn everything from library preparation and antigen biotinylation to MACS and FACS cell sorting. Find out more: buff.ly/AFAVmuP

Did you know @addgene.bsky.social now offers antibodies? You can find 200+ #antibodies in their catalog — including IPI recombinants targeting #Netrin, #PUNC, #DCC, #Neurexin, #Neuroligin, #Glypican, #Integrin and more. Browse here:

Good antibodies start with good data. Our new anti-DCC, anti-Netrin-1, and anti-IGDCC3 (PUNC) #antibodies come with full validation datasets—including demonstrated lack of #crossreactivity. Take a closer look: buff.ly/LLL78N2

IPI’s Haisun Zhu worked with the Chen Lab (@harvardmed.bsky.social @bostonchildrens.bsky.social) to pinpoint the role of the S2’ cleavage in the SARS-CoV-2 spike protein. Their @natcomms.nature.com paper gives new details of pathogen entry that might guide future interventions ➡️ buff.ly/F9Xv2FJ