Frequent user of epitope tags? Try ours! IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social! buff.ly/YEuZDIp

What drives science forward? People like Senior Automation Engineer Eloy Salinas, who is always on the lookout for ways to innovate in the lab. Learn more about the IPI platform: buff.ly/91pXA1d #proteinscience #proteome #labautomation #proteininnovation

Lots of excitement at the Discovery on Target conference next week! 🎯André Teixeira will share IPI's high-throughput discovery platform and lead a discussion on GPCR #abdiscovery (Sept. 23) 🎯IPI co-founder Tim Springer will give a keynote on #integrins and their role in organoid formation (Sept. 24)

Big week at the International Antibody Validation Meeting! Deb Moshinsky shared our #abvalidation system, already powering our #GPCs & #NLGN antibodies, and Travis Riedel noted the need for validated GPC #monoclonals. Even better — we connected with scientists pushing antibody validation forward!

Prabakaran Ponraj is now boosting bioinformatic analysis at IPI — and he’s coauthor on a recent NaturalAntibody paper that mapped #antibody chain preferences & structural interactions to guide better therapeutics. Read more! www.nature.com/articles/s42...

What drives Aditi Kachare’s #antibodycharacterization work at IPI? The chance to push science and research forward, a step at a time. We’re spotlighting the people behind the scenes at IPI this fall. Follow along to see what else drives our science! #whatdrivesmyscience #proteinscience #bioscience

Thanks @addgene.bsky.social, @dshb-antibodies.bsky.social & #NeuroMab for the shoutout in New Biotechnology! Inspired by #opensourcesoftware, they’re calling for more opensource #antibodies to make science reliable, affordable and shareable. Read more: www.sciencedirect.com/science/arti...

At IPI, we’re building #antibodies to explore neurodegenerative targets, including #Ephrin & #Semaphorin. That’s why we’re excited by a landmark data set from @neuroproteome.bsky.social revealing #proteomic signatures in Alzheimer’s, Parkinson’s & more. Take a look! www.nature.com/articles/s41...

What drives protein science at IPI? We asked our team — and the answers totally wowed us! We’re featuring their responses this fall, starting with IPI research associate Robert May. Come along with us on the ride! #whatdrivesmyscience #proteinscience #bioscience #antibodydiscovery #research

Find our antibody characteriazation and validation director Deb Moshinsky in England next week 🇬🇧 Registration is still open for the 5th International Antibody Validation Meeting @uniofbath.bsky.social — join us! #abval25 www.antibodyvalidation.co.uk

Thanks for spending the summer with us! We’re saying a bittersweet goodbye to our wonderful interns, after months of hard work in the lab. Good luck this fall—we look forward to seeing where your paths lead!

The @neuroproteome.bsky.social has released 250M protein measurements from 35K+ samples, revealing #proteomic signatures in Alzheimer’s, Parkinson’s & more. At IPI, we’re building #antibodies to explore some of the targets, including #Ephrin & #Semaphorin. Read more: www.nature.com/articles/s41...

Our Neuroscience team has been steadily growing over the past year, gearing up for investigations into axon guidance, synapse formation and glial cell phenotyping. We can’t wait to see what they uncover!

What does a day in the life of an IPI intern look like? 🧑🔬 Find out from Benjamin Pomianek, a University of Michigan @umich.edu undergrad who spent the summer on our antibody characterization and validation team! IPI video by Julia Chan.

We spent an incredible few days exploring information processing, brain development, neuropathologies, therapeutic progress, transcriptomics and more at this year’s Changing Brain conference. Thank you to @ucirvine.bsky.social, @cajalclub.bsky.social & @alleninstitute.org for such a memorable event!

Day 2 of Changing Brain! IPI’s Rob Meijers and Mike Walden are just heading over for another day of neuroscience talks at UC Irvine. Come say hello & learn how we’re supporting neuroscience research with novel protein reagents! #neuroskyence 💪⚖️ Learn more about IPI: shorturl.at/zKjOU

Our #labautomation team is intrigued by PANCS-Binders, a #phage-assisted in vivo selection platform that could accelerate & simplify #binderdiscovery developed by a @uchicagopsd.bsky.social & @czbiohub.bsky.social team 🧪🤖 Read about it @natmethods.nature.com: www.nature.com/articles/s41...

How do ligand-receptor interactions dictate axon pathfinding and neural function? There's no easy answer, but scientists at IPI are making progress. Find out more ➡️ buff.ly/KsmRndV

We’re excited for The Changing Brain conference next week, sponsored by CNCM @ucirvine.bsky.social, @cajalclub.bsky.social & @alleninstitute.org. There’s a packed speaker lineup — what’s your “can’t miss” talk? cncm.som.uci.edu/2025-cncm-co... #neuroskyence #neuralcircuitry #changingbrain

Looking for #glypican, #integrin or #epitopetag antibodies? Browse our #antibody catalog and order today ➡️➡️ proteininnovation.org/glypican-ant...

Thanks Melody Wang & Samuel Mohler for joining us and a group of Emmanuel College students last week to share some of the exciting career paths that exist in the world of #labautomation. As #AI and automation take the lab by storm, there is still plenty of opportunity and room for innovation!

#IPISeminar next Tuesday ➡️ Charles Lee @jacksonlab.bsky.social will present on the identification and characterization of #structuralgenomicvariants using advanced technology platforms. Come join us! 1:30 p.m. ET in the Bray Room @harvardmed.bsky.social, or on Zoom! rb.gy/xcee9l

We had a great time last week teaching a talented group of Emmanuel College students the basics of #labautomation and #liquidhandling, inc #Opentrons T-2 & protocol design, Python & AI, copper sulfate & Bradford assays and more. Big thanks to our wonderful Automation Team & creative students!

Nice article from @xinruw.bsky.social & David Baker @uwproteindesign.bsky.social w/IPI cofounder Timothy Springer and others. They engineered a de novo #miniprotein, #NeoNectin, that could enhance cell attachment & spreading through binding with #integrin α5β1 ➡️ pubmed.ncbi.nlm.nih.gov/40489013/

Behind the scenes at IPI 🔬

An NIH team w/IPI cofounder Andrew Kruse developed mutant M3 receptors with distinct signaling preferences. These tools could help uncover how M3R signaling shapes physiology and inform next-gen therapeutics with fewer side effects. pubs.acs.org/doi/abs/10.1...

IPI principal scientist Shaotong Zhu recently returned from presenting IPI’s antibody development efforts targeting the synaptic cleft at the Surfaceome Conference in Scanno, Italy—a fantastic gathering of neuroscientists investigating synapse formation, plasticity, and more!

“We view the @ycharos.bsky.social platform not just as a methodology, but as a movement to echo our long-standing belief in robust, reproducible, scientific research.” Great insights from @cellsignal.com, thanks for sharing! blog.cellsignal.com/antibody-val...

What can we extract from our #antibody selection data? Certainly more — with #AI on our side. Read how IPI and collaborators @harvardmed.bsky.social applied #machinelearning and #artificialintelligence to streamline #antibodydiscovery for cell surface #antigens. proteininnovation.org/2025/05/mach...

A @csisingapore.bsky.social team showed D-I-Tasser can outperform AlphaFold2/3, elevating high-accuracy protein structure & function predictions. We wonder if this moves us closer to resolving protein–protein complex structure prediction? @natbiotech.nature.com www.nature.com/articles/s41...

Automation fun in the lab this month 🤖 🧪

Ever wonder what’s happening at the IPI bench? Here’s your chance to snoop! Take a look at what our scientists are up to, as presented at #PEGSummit last month 👀 proteininnovation.org/2025/05/ipi-...

In a recent review paper out of the NIH, Hsi-En Tsao and Mitchell Ho detail the modulatory role of #glypicans in #Wntsignaling & underscore the need for better blueprints of glypican/Wnt/Fzd complexes. Check out their mini review 📝 onlinelibrary.wiley.com/doi/full/10....

IPI Senior Scientist Anita Ghosh will join a ‪@cytiva.bsky.social‬ miniconference at Pfizer tomorrow to discuss high throughput #proteinpurification and other advances. Registration is still open — find out more! 🧬🧶 #protein #proteinscience info.cytivalifesciences.com/cambridge-ak...

During this episode, @fang-xie.bsky.social and I interview @cdbahl.com, co-founder and CEO of @aiproteins.com. We discuss with Chris his interest in protein science and how he started his academic lab at the @ipiproteins.bsky.social.

In a #preprint released earlier this year, a Colorado State University-based team successfully converted #antibodysequences into functional #scFvs — using an #AI-driven method that could ease #intrabody design & development. Take a look! #proteindesign 🧬🧶 www.biorxiv.org/content/10.1...

Pengxiang Huang of @bcmhouston.bsky.social‬ joins us for our next #IPISeminar today at 2 p.m. EST to share work on #signaltransduction in the #Hedgehog & #Wnt pathways! Follow the QR Code below or find the Zoom link on our calendar ➡️ rb.gy/xcee9l #neuroskyence #proteinscience

First yeast display course = complete ✅ We spent an impactful week exploring #yeastdisplay (library construction to FACS to NGS prep) with a curious, focused & thoughtful group. Stay tuned—we’re just getting started! mailchi.mp/proteininnov... #antibodydiscovery #proteinengineering

Deb Moshinsky, IPI’s characterization & validation expert, will join this year’s #Antibody Validation Meeting @uniofbath.bsky.social‬ this Sept 🧑‍🔬 Poster abstracts are due 6/30 & registration is open all summer. Come chat #Abvalidation best practices! #abval25 www.antibodyvalidation.co.uk

Holistic antibody discovery and bespoke production workflow. Specially crafted yeast display libraries and #AI wizardry. Read what IPI scientists had to share last month at the #PEGSummit! proteininnovation.org/2025/05/ipi-...

Our #yeastdisplay for #antibodydiscovery course is off to a great start here on the Emmanuel College campus, with talks from IPI senior platform director André Teixeira, IPI scientist Deepash Kothiwal and Angela Reslow of Miltenyi Biotec yesterday! More learning to come!

We’ve got data — an unprecedented amount of publicly available #antibodysequence data, in fact. Read how IPI & @harvardmed.bsky.social collaborators used AI/ML to pull out new insights, then see what you might find in the haystack 🔍🌾 proteininnovation.org/2025/05/mach...

How much impact can a paper have? Turns out, a lot. Take a look @thetransmitter.bsky.social‬’s “This paper changed my life” & show your favorite papers some love! www.thetransmitter.org/this-paper-c...

We’re looking forward to sharing our knowledge on #yeastdisplay & #antibodydiscovery with 12 learners in our summer course next week! Sign up to our newsletter for the latest on #IPIeducation! mailchi.mp/proteininnov...

It’s that time of year in Boston when the flowers bloom, the trees bud and the protein science community emerges from labs across the country to make the migration, long or short, to #PEGSummit. This year, IPI had plenty to add to the conversation. Read more! proteininnovation.org/2025/05/ipi-...

How to accelerate, discover, & streamline antibody development! @ipiproteins.bsky.social & @harvardmed.bsky.social report a novel framework for making synthetic recombinant antibodies that can generate data specifically optimized for machine learning integration.

IPI is happy to support the ‪@ucirvine.bsky.social‬ CNCM Changing Brain conference, a showcase of neural circuit studies in health and disease, genes, cell types, systems, disorders & more. Register by June 1! 🧠 cncm.som.uci.edu/2025-cncm-co... #neuroskyence #neuralcircuits

Working with #integrin or #glypican antibodies? Need a reliable plasmid or #antibody build to target #epitopetags? View our catalog and order IPI antibodies through @addgene today! proteininnovation.org/protein-reso...

Can #machinelearning really accelerate antibody discovery? In a new preprint, our team shows ML’s potential to enhance #antibodydiscovery when fed well-curated #datasets of #antibody/#antigen interactions 👏 👏 👏

Come listen to IPI’s Deborah Moshinsky at the YCharOS Inc./F1000 webinar on May 29th! She’ll join other speakers to chat about the YCharOS Gateway, antibody characterization data & peer review and publishing on #F1000Research. Register now! events.teams.microsoft.com/event/7e3571...