Institute for Protein Innovation
@ipiproteins.bsky.social
📤 290
📥 263
📝 196
We advance protein science to accelerate research & improve human health | proteininnovation.org
pinned post!
📢 IPI is excited to announce the launch of the Springer-Lu
#PostdoctoralFellowship!📢
We’re recruiting an early-career fellow to apply IPI's platform to cutting-edge investigations in
#proteinscience
&
#molecularbiology
. Apply now!
buff.ly/lCULeU4
#PostDocJobs
#PostdocPosition
#PhDChat
#ScienceJobs
3 months ago
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HMS MEDscienceWorks program graduates joined IPI at Emmanuel College this week to learn lab automation, assays and
#Python-powered
liquid handling. Training the
#nextgen
of
#bioscientists
is a big responsibility—one we’re excited to take on as we roll out new courses this year. More soon!
2 days ago
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Applications to the IPI Springer-Lu Postdoctoral Fellowship are due on Jan. 20, 2026 — that’s two weeks away! Apply now:
buff.ly/Fp8rh51
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5 days ago
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Proteins positioned within the
#synapticcleft
govern
#synapse
formation, maintenance and
#neurotransmission
. But the exact architecture of this space is still a mystery. IPI’s new
#NRXN
and
#NLGN
antibodies could help reveal the blueprint. Order now:
buff.ly/AtBazlt
6 days ago
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As AI and machine learning capabilities expand, IPI is building nextgeneration Fab and VHH yeast display libraries to yield molecules with better developability. Our bioinformatics scientist Hoan Nguyen is central to this effort!
#bioinformatics
#proteinscience
#proteomics
#AI
16 days ago
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Lab coats off, holiday spirit on. 🎄✨ We’re wrapping up the year with the people who make our research possible. Cheers to a strong 2025 — and a bright year ahead!
19 days ago
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New from the Mizuno Lab, with help from IPI’s Nirakar Basnet: insights into how
#microtubule
shoots stabilize and repair
#axons
— and how epothilone B drives CNS regeneration. Read it in Nature:
buff.ly/lO9xwIX
20 days ago
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🗓️Mark your calendars 🗓️ Applications for the IPI Springer-Lu Postdoctoral Fellowship are due in ONE MONTH. Find out how to apply:
buff.ly/2b45pWI
#neurojobs
#sciencejobs
#postdocjobs
#proteinscience
#proteinengineering
22 days ago
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IPI’s glypican antibodies are used in labs around the world to study neurodegenerative diseases, brain development, cancer biology and more — and our collection with
@addgene.bsky.social
just expanded 🤯 Order reliable recombinant antibodies targeting GPCs 1-6 on our website:
buff.ly/QSwEnbQ
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Glypican antibody collection
Highly specific recombinant glypican (GPC) antibodies, validated for Flow cytometry and Immunofluorescence applications. Buy with Addgene!
https://buff.ly/QSwEnbQ
24 days ago
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We’re excited to announce our plans for a course on antibody validation and characterization — and we need your help! Fill out this survey to shape the course (it’s quick, we promise!) ➡️
buff.ly/KoyJfU9
25 days ago
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IPI has launched a postdoc for scientists working in cell-surface protein research/antibody engineering — and we’ve expanded eligibility to include recent MD/PhD/MD-PhD grads + early-career postdocs! Come work with us!
buff.ly/45QGcpW
#proteinscience
#postdocjobs
#neurojobs
27 days ago
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IPI collaborator Matthew Dalva (
@tulanebrain.bsky.social
) has a new paper out on the role of extracellular phosphorylation in regulating receptor interactions at synapses, with particular focus on
#EphrinB2-NMDAR
interaction. Take a look
@science.org
đź‘€
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The synaptic ectokinase VLK triggers the EphB2–NMDAR interaction to drive injury-induced pain
Phosphorylation of hundreds of protein extracellular domains is mediated by two kinase families but the functional role of these kinases is underexplored. We find that the presynaptic release of the…
https://buff.ly/CPX9k0f
about 1 month ago
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IPI is accepting applications to its FIRST postdoctoral fellowship program. Apply now for a 2+ year opportunity to push the boundaries of antibody science and cell-surface protein research!
#neurojobs
#phdjobs
#proteinscience
buff.ly/MPh7dR8
about 1 month ago
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Breakthrough work
@uwproteindesign.bsky.social
combines computation & yeast display to produce
#denovo
antibodies w/ “atomic accuracy.” We’re exploring how yeast display—key to IPI’s platform—can work in conjunction with AI. More
@nature.com
:
buff.ly/6CJDfzM
about 1 month ago
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What do autism, Alzheimer’s, schizophrenia, depression and obesity have in common? They’ve been linked to mutations in
#neurexin
genes—and IPI
#monoclonalantibodies
could help researchers learn more. Order IPI antibodies, including Neurexin 1/2/3:
buff.ly/ZUSDGZU
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Synaptic cleft antibody collection
Neuronal communication and neurological function rely on chemical signaling across a narrow extracellular space known as the synaptic cleft. Proteins positione
https://buff.ly/ZUSDGZU
about 1 month ago
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We brought the Antibodies Roadshow back to
#SfN2025
— this time on the USS Midway. Researchers shared new
#imagingtools
, community
#antibodydata
, and advances in
#synapticbiology
and
#braincircuitry
. Read the recap:
buff.ly/60ouG8A
about 1 month ago
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Are you a recent or soon-to-be PhD graduate who wants to work with
#yeastdisplay
, deep sequencing,
#proteinexpression
,
#biophysicalcharacterization
,
#antibodyvalidation
,
#confocalmicroscopy
,
#AI
,
#ML
or
#automation
? Apply to be an IPI
#postdoc
!
buff.ly/jvpT6MP
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Springer-Lu Postdoctoral Fellowship
Sorry, this product is unavailable. Please choose a different combination.
https://buff.ly/jvpT6MP
about 1 month ago
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Happy thanksgiving from IPI! We’re feeling especially grateful this week for our team and the many scientists, collaborators and partners who share our passion for advancing protein science. Your curiosity drives progress — and inspires us every day 🍂🧬
about 2 months ago
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Congrats to IPI postdoctoral fellow Nirakar Basnet for co-authoring a recent paper
@natcomms.nature.com
with former colleagues at the Mizuno Lab. They resolved the
#cryoEM
structure of
#SSNA-1
, providing a detailed look at its self-assembly and role in
#embryonicdevelopment
➡️
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Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance - Nature Communications
Cryo-EM shows SSNA-1 forms anti-parallel coiled-coils with a triple-helical junction for microtubule binding. Disrupting self-assembly or deleting SSNA-1 reduces C. elegans embryonic viability and…
https://buff.ly/JdVwNw1
about 2 months ago
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Scientists are drawn to their
#research
for all sorts of reasons, big and small. “What drives my science,” says IPI scientist Alex Morano, “is profound love of humanity and a desire to make the world better and safer for people.” Learn more about IPI’s story:
buff.ly/ifaeFo9
#whatdrivesmyscience
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about 2 months ago
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There’s some exciting work happening w/
#neuroscience
&
#antibodies—PRISM
barcoding,
#synaptome
mapping w/ ExA-SPIM,
#wholebraintissueclearing
and more. Huge thanks to the speakers who shared this work at a recent IPI meeting down the road (harbor? 🚢) from
#SfN2025
. Read more:
buff.ly/Utn94ct
about 2 months ago
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Come work with us! IPI is seeking a
#postdoctoralfellow
to join us and apply our
#antibodydiscovery
platforms to cutting-edge questions in
#cellsurface
#proteinresearch
and
#antibodyengineering
. It could be you! Learn how to apply today:
buff.ly/f2cLV4D
about 2 months ago
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🛑 Are you using glypican antibodies to study brain development, neurodegeneration, cancer biology or cell signaling? 🛑 IPI has recombinant antibodies to GPC1-6 and we want you to know about them! So, what’s amazing about our anti-glypicans?
about 2 months ago
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We had such a great time yesterday diving into cell-cell communication and the latest advances in molecular neuroscience on a rainy San Diego day!
#SfN2025
about 2 months ago
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reposted by
Institute for Protein Innovation
Addgene
about 2 months ago
New recombinant monoclonal antibodies from @ipiproteins.bsky.social at Addgene targeting Neurexin and Neuroligin — key mediators of synaptic adhesion and function. Explore the collection and advance your neuroscience research:
https://twp.ai/4itA72
#neuroscience
#neuroskyence
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🚨IPI just released new antibodies into the
@addgene.bsky.social
catalog targeting Neurexin 1/2/3 & Neuroligin 1. Order now!
buff.ly/CpP2b8x
#ProteinScience
#Neuroscience
#Antibodies
about 2 months ago
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IPI
#researchassociate
Minh Anh Kieu helps build and optimize our high-throughput antibody production pipeline — perfect for a problem-solver like her. Find out more about
#antibodyproduction
at IPI and stay tuned for what drives our science!
buff.ly/V4wps8X
#proteinscience
#proteomics
#bioscience
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about 2 months ago
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Applications for the Springer-Lu Postdoctoral Fellowship are due Jan. 20 — but now is the perfect time to put your application together, reach out to an external faculty sponsor and apply! Learn more and apply today 👉
buff.ly/vZ4QNLw
2 months ago
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reposted by
Institute for Protein Innovation
Addgene
2 months ago
Come discuss antibodies with @ipiproteins.bsky.social at
#SfN25!
Join us Monday, Nov 17 (11–3) in booth # 3625 for IPI office hours. Let’s chat about new tools for axon guidance & the synaptic cleft — and what antibodies you want to see next.
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We’re looking forward to the Society for Neuroscience (
@sfn.org
) conference in San Diego next week! Our team will be catching talks on everything from neuronal cell types to pathways of neurodevelopment and degeneration — and we’d love to connect while we’re there. Here’s where to find us:
2 months ago
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IPI just released new glypican antibodies (GPCs1-6) — but what’s a glypican anyway? Read our explainer to find out! Link in bio.
buff.ly/LezYIdl
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Glypicans: Explained
Hundreds of millions of years before humans evolved, a family of proteins came to be — first in worms, next in flies, then in mammals. The proteins,
https://buff.ly/LezYIdl
2 months ago
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“What drives my research is the real-world impact that we make,” says Swethika Balasankar, a research associate on IPI’s
#AntibodyDiscovery
team. Find out more about how IPI is shaping
#proteinscience
🔬
buff.ly/Fd2qroB
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2 months ago
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Looking for a
#postdoc
in applied protein science and engineering? Check out the IPI Springer-Lu Postdoctoral Fellowship. Applications are open until Jan. 20!
buff.ly/ko7q2QE
#PostDocJobs
#PostdocPosition
#PhDChat
#ScienceJobs
#PostdoctoralFellow
#STEMCareers
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Springer-Lu Postdoctoral Fellowship
Sorry, this product is unavailable. Please choose a different combination.
https://buff.ly/ko7q2QE
2 months ago
1
5
2
IPI has new glypican
#antibodies
available! Our latest synthetic
#recombinants
target
#GPC1
,
#GPC2
,
#GPC4
,
#GPC5
and
#GPC6
— which means IPI’s collection now targets the full
#glypican
family. View our catalog & order today:
buff.ly/4zh0UfE
loading . . .
Glypican antibody collection
Highly specific recombinant glypican (GPC) antibodies, validated for Flow cytometry and Immunofluorescence applications. Buy with Addgene!
https://buff.ly/4zh0UfE
2 months ago
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What drives Sophea Sann-Rorth’s work at IPI? Seeing how incremental experiments step us closer to understanding human health and saving people’s lives. At IPI, we provide synthetic antibodies and deep protein expertise, empowering this progress. Join our newsletter to learn more!
buff.ly/0M4VsFX
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2 months ago
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As a postdoc in the Milstein lab, IPI co-founder Tim Springer learned the power of
#monoclonalantibodies
— a discovery that defined his career. Now, he’s paying it forward with a new
#postdoctoralfellowship
supporting the next generation of
#proteinscience
. Learn more & apply today:
buff.ly/RVoRcDV
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IPI debuts Springer-Lu Postdoctoral Fellowship to support the next generation of protein scientists
The Institute for Protein Innovation (IPI), a nonprofit research institute dedicated to advancing protein science, today celebrates the extension of its
https://buff.ly/RVoRcDV
2 months ago
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Buried in the history of
#monoclonalantibodies
is a lesson in the open exchange of knowledge and materials. Read the story in Nature:
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Monoclonal antibodies revolutionized biomedical science and health care
The story of the discovery of these molecules 50 years ago shows how the free exchange of ideas can lead to life-changing treatments.
https://buff.ly/nD1lLEM
3 months ago
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In 2021, Chang Yang joined IPI as a senior research associate. By 2025, she had co-authored a book chapter, mentored teammates, and contributed to a massive increase in antigen production. Read her story:
buff.ly/Bj2riuS
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Chang Yang grows with IPI — and goes beyond
When Chang Yang joined the Institute for Protein Innovation (IPI) in 2021, she was just beginning her career — and IPI was a small nonprofit lab still
https://buff.ly/Bj2riuS
3 months ago
0
1
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Have you heard? IPI is accepting applications to its FIRST
#postdoctoralfellowship
. Apply now for a 2+ year opportunity to push the boundaries of antibody science and cell-surface protein research:
buff.ly/tQ6AWzA
3 months ago
1
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It’s the people at IPI and big picture impact that make all the hard work worth it for research associate Karunya Rajaraman. Find out more about protein science at IPI:
buff.ly/0tw6hUq
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3 months ago
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The role of glypicans in the nervous system is still being uncovered. In this preprint, researchers
@hopkinsmedicine.bsky.social
@oneneurojhu.org
show GPC6 plays a role in nuclear pore complex integrity and TDP-43 nuclear function, with potential to impact neurological function ➡️
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Regulation of Glypican 6-mediated Wnt activation maintains TDP-43 nuclear localization in neurons
Abnormalities in TDP-43 (Transactive response DNA-binding protein 43kDa) localization and function span multiple neurodegenerative diseases and are implicated in driving neuronal degeneration and…
https://buff.ly/jXESGa4
3 months ago
0
0
0
📢 IPI is excited to announce the launch of the Springer-Lu
#PostdoctoralFellowship!📢
We’re recruiting an early-career fellow to apply IPI's platform to cutting-edge investigations in
#proteinscience
&
#molecularbiology
. Apply now!
buff.ly/lCULeU4
#PostDocJobs
#PostdocPosition
#PhDChat
#ScienceJobs
3 months ago
1
2
1
Hello from the
#PRIMESummit
@cytiva.bsky.social
! What an incredible opportunity to get into the details of
#proteinpurification
,
#labautomation
and
#antibodydiscovery
, right here in Boston! Learn more about the IPI platform:
buff.ly/zNIF9vw
3 months ago
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This fall, we’re diving behind the scenes to hear what drives protein science research at IPI. For IPI research associate Chris Lowe, it’s the constant excitement of lab automation! Learn more about IPI:
buff.ly/4ui9uS8
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3 months ago
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We’re happy to see
@addgene.bsky.social
President and Executive Director Chonnettia Jones named one of Endpoints News 2025 Top Women in Biopharma R&D — a wonderful addition to the list and a valued partner in IPI antibody distribution!
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Meet 20 women reshaping biopharma, from early discovery to patient advocacy
A project highlighting women in biopharma has grown since 2019, now honoring over 140 women who've shaped the industry through work on rare diseases, IPOs, AI drug discovery and patient advocacy.…
https://buff.ly/BAulVmy
3 months ago
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“What drives my research is the fact that IPI is a nonprofit and committed to open science,” says IPI research associate Leo Fletcher. Find out more about how we’re providing protein tools and knowledge to the research community!
buff.ly/r0Aheai
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3 months ago
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reposted by
Institute for Protein Innovation
Addgene
3 months ago
Chonnettia Jones, Addgene’s President & Executive Director, is one of Endpoints News’ 2025 Top Women in Biopharma R&D! She is driving Addgene’s growth to enable more discovery and innovation, powered by the sharing of scientific resources. 🔗
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endpoints.news
Meet 20 women reshaping biopharma, from early discovery to patient advocacy
https://twp.ai/4is1cF
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For Chang Yang, science is personal. The early loss of her grandmother to cancer inspired a career in
#biotechnology
— and, at IPI, she found the tools and mentorship to grow as a scientist. Read more:
buff.ly/Eif7FQB
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Chang Yang grows with IPI — and goes beyond
When Chang Yang joined the Institute for Protein Innovation (IPI) in 2021, she was just beginning her career — and IPI was a small nonprofit lab still
https://buff.ly/Eif7FQB
3 months ago
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“What drives my research is my passion for immunology,” says IPI
#researchassociate
Fabbiha Hossain. Here at IPI, we play a role , but our
#proteinreagents
go on to impact
#biologicaldiscovery
in a multitude of ways, including in the field of
#immunology
. Learn more about IPI:
buff.ly/HHMWKf5
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3 months ago
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Using a synthetic yeast display nanobody library, IPI cofounder Andrew Kruse &
@harvardmed.bsky.social
colleagues found
#nanobodies
that modulate AT1R function, distinct from small molecules. A promising step for nanobody drugs & compelling use of
#yeastdisplay
➡️
academic.oup.com/mam/article/...
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Structural Insights into Antibody-based Inhibition of the Angiotensin Receptor
The angiotensin II type I receptor (AT1R), a G protein-coupled receptor (GPCR) that regulates cardiac and renal function, is one of the most successful pha
https://academic.oup.com/mam/article/31/Supplement_1/ozaf048.365/8212939
3 months ago
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It’s conference season! We're just back from AXON2025 & Discovery on Target where we: shared progress on antibodies to 50+ neuronal targets, discussed strategies for
#membraneprotein
and
#GPCR
discovery & met determined researchers in
#braindevelopment
#synapticplasticity
#antibodydiscovery
& more.
4 months ago
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