Is it only March? It’s been a busy year so far! We kicked off the year hosting a lab automation course with HMS MEDscienceWorks at Emmanuel College.

One month left to apply to our hands-on #yeastdisplay course! Learn more ➡️ buff.ly/XpRYLOC

New Neurexin and Neuroligin antibodies just joined our Synaptic Cleft Antibody Collection, available through @addgene.bsky.social: 🔹 IPI-NRXN1α 🔹 IPI-NRXN2α 🔹 IPI-NRXN3α 🔹 IPI-NLGN2 🔹 IPI-NLGN3 View more data ➡️ buff.ly/YYL1WWE

A new @pnas.org study caught the eye of our bioinformatics team with its identification of ~4,500 targetable binding sites & binding seeds across human cell surface proteins—giving IPI and other labs a protein design launch point.

Applications for our 2026 Yeast Display Technology for Antibody Discovery course are due on March 30th. Here’s what you need to know! Apply now! buff.ly/lag7LwW

Attending #SLAS2026 earlier this month was incredibly valuable for our Automation and Education teams as we think about how to build new resources for lab automation training. Here are a few of our biggest takeaways:

New #Neurexin and #Neuroligin antibodies just joined our Synaptic Cleft Antibody Collection today, available through @addgene.bsky.social — 🔹 IPI-NRXN1α 🔹 IPI-NRXN2α 🔹 IPI-NRXN3α 🔹 IPI-NLGN2 🔹 IPI-NLGN3 buff.ly/YYL1WWE

What does antibody discovery mean at IPI? It means using FACS and MACS to winnow a vast yeast synthetic library, with 10^10 unique sequences, down to just a few highly selective, tight-binding antibodies that hold potential as research reagents and therapeutics.

Our director of automation, Curtis Walton, joined Opentrons on their Designing Open Science podcast last week. Listen to learn about IPI’s scalable, automated systems that support IPI scientists at the bench!

Axon guidance shapes how #neurons connect—and proteins like #Netrin-1, #DCC and #PUNC sit at the center of this process 🧠 IPI now offers #recombinantantibodies to all three targets, backed by solid validation data. Explore our reagents: buff.ly/T1CktaD

IPI’s #yeastdisplay course is back by popular demand! Join us in June to learn the basics & hear directly from experts Dane Wittrup (@mitkochinstitute.bsky.social), @surgebiswas.bsky.social (Nabla Bio) & Justin Peruzzi (@aiproteins.com). Applications are due on March 30! buff.ly/KmY7N86

We kicked off #SLAS2026 (@slasorg.bsky.social) by teaching a short course on automated liquid handling to some wonderful, engaged scientists and presenting our approaches to purification and integrated lab systems. Still time to find us to share strategies, approaches, hot-takes, etc!

Hello from #SLAS2026 (@slasorg.bsky.social)! We shared automation tips as part of a liquid handling short course today, and we're excited to connect all week. Come find us! 👉 Feb 9-11: Posters on characterization, purification, integrated systems & more 👉 Feb 11: IPI talks automation ed w/ Opentrons

We’re bringing our five-day yeast display course back for 2026! Last summer, 12 researchers from around the world joined IPI to learn the principles, applications and methods of #yeastdisplaytechnology — this year it could be you! Apply to join us this June: buff.ly/IOLmxV2

Applications for IPI’s 2026 Yeast Display Technology for Antibody Discovery course are now open! Join us for 5 days this June to learn everything from library preparation and antigen biotinylation to MACS and FACS cell sorting. Find out more: buff.ly/AFAVmuP

Did you know @addgene.bsky.social now offers antibodies? You can find 200+ #antibodies in their catalog — including IPI recombinants targeting #Netrin, #PUNC, #DCC, #Neurexin, #Neuroligin, #Glypican, #Integrin and more. Browse here:

Good antibodies start with good data. Our new anti-DCC, anti-Netrin-1, and anti-IGDCC3 (PUNC) #antibodies come with full validation datasets—including demonstrated lack of #crossreactivity. Take a closer look: buff.ly/LLL78N2

IPI’s Haisun Zhu worked with the Chen Lab (@harvardmed.bsky.social @bostonchildrens.bsky.social) to pinpoint the role of the S2’ cleavage in the SARS-CoV-2 spike protein. Their @natcomms.nature.com paper gives new details of pathogen entry that might guide future interventions ➡️ buff.ly/F9Xv2FJ

Applications are due TOMORROW for IPI’s Springer-Lu Postdoctoral Fellowship program. Apply now! buff.ly/BSjUH53 #proteinresearch #PhDJobs #postdocjobs #proteomics #proteinengineering #antibodyresearch

Come work with us! Apply this week for the IPI Springer-Lu Postdoctoral Fellowship in cell-surface protein research and antibody engineering. Apply by Jan. 20! buff.ly/w6AKPdd

IPI teamed up with @deboramarks.bsky.social & Andrew Kruse @harvardmed.bsky.social to design optimized #nanobody binders using #ML on single-sort sequencing data. The approach could speed discovery by reducing the need for multi-sort #affinitymaturation. Read more:

IPI has new #recombinant antibodies available against DCC, anti-Netrin-1 and anti-IGDCC3 (PUNC), key players in axon guidance! Explore the datasheets and order here 👉 buff.ly/KYdEvur

Apply to the Springer-Lu Postdoctoral Fellowship to secure a place at IPI and 2+ years of funding to pursue ambitious research in #proteinresearch and #antibodyengineering. Applications close in one week on Jan. 20: buff.ly/CCEOKjO #PostDocJobs #PostDocPosition #PhDChat #ScienceJobs #STEMCareers

IPI is recruiting a new commercial director! This senior leadership role is a wonderful opportunity to help translate world-class protein science and technology into real-world impact. Find out more: buff.ly/4OvJUnF #sciencejobs #proteinscience #proteomics #commercialdirector #antibodyreagents 🧪

HMS MEDscienceWorks program graduates joined IPI at Emmanuel College this week to learn lab automation, assays and #Python-powered liquid handling. Training the #nextgen of #bioscientists is a big responsibility—one we’re excited to take on as we roll out new courses this year. More soon!

Applications to the IPI Springer-Lu Postdoctoral Fellowship are due on Jan. 20, 2026 — that’s two weeks away! Apply now: buff.ly/Fp8rh51

Proteins positioned within the #synapticcleft govern #synapse formation, maintenance and #neurotransmission. But the exact architecture of this space is still a mystery. IPI’s new #NRXN and #NLGN antibodies could help reveal the blueprint. Order now: buff.ly/AtBazlt

As AI and machine learning capabilities expand, IPI is building nextgeneration Fab and VHH yeast display libraries to yield molecules with better developability. Our bioinformatics scientist Hoan Nguyen is central to this effort! #bioinformatics #proteinscience #proteomics #AI

Lab coats off, holiday spirit on. 🎄✨ We’re wrapping up the year with the people who make our research possible. Cheers to a strong 2025 — and a bright year ahead!

New from the Mizuno Lab, with help from IPI’s Nirakar Basnet: insights into how #microtubule shoots stabilize and repair #axons — and how epothilone B drives CNS regeneration. Read it in Nature: buff.ly/lO9xwIX

🗓️Mark your calendars 🗓️ Applications for the IPI Springer-Lu Postdoctoral Fellowship are due in ONE MONTH. Find out how to apply: buff.ly/2b45pWI #neurojobs #sciencejobs #postdocjobs #proteinscience #proteinengineering

IPI’s glypican antibodies are used in labs around the world to study neurodegenerative diseases, brain development, cancer biology and more — and our collection with @addgene.bsky.social just expanded 🤯 Order reliable recombinant antibodies targeting GPCs 1-6 on our website: buff.ly/QSwEnbQ

We’re excited to announce our plans for a course on antibody validation and characterization — and we need your help! Fill out this survey to shape the course (it’s quick, we promise!) ➡️ buff.ly/KoyJfU9

IPI has launched a postdoc for scientists working in cell-surface protein research/antibody engineering — and we’ve expanded eligibility to include recent MD/PhD/MD-PhD grads + early-career postdocs! Come work with us! buff.ly/45QGcpW #proteinscience #postdocjobs #neurojobs

IPI collaborator Matthew Dalva (@tulanebrain.bsky.social) has a new paper out on the role of extracellular phosphorylation in regulating receptor interactions at synapses, with particular focus on #EphrinB2-NMDAR interaction. Take a look @science.org 👀

IPI is accepting applications to its FIRST postdoctoral fellowship program. Apply now for a 2+ year opportunity to push the boundaries of antibody science and cell-surface protein research! #neurojobs #phdjobs #proteinscience buff.ly/MPh7dR8

Breakthrough work @uwproteindesign.bsky.social combines computation & yeast display to produce #denovo antibodies w/ “atomic accuracy.” We’re exploring how yeast display—key to IPI’s platform—can work in conjunction with AI. More @nature.com: buff.ly/6CJDfzM

What do autism, Alzheimer’s, schizophrenia, depression and obesity have in common? They’ve been linked to mutations in #neurexin genes—and IPI #monoclonalantibodies could help researchers learn more. Order IPI antibodies, including Neurexin 1/2/3: buff.ly/ZUSDGZU

We brought the Antibodies Roadshow back to #SfN2025 — this time on the USS Midway. Researchers shared new #imagingtools, community #antibodydata, and advances in #synapticbiology and #braincircuitry. Read the recap: buff.ly/60ouG8A

Are you a recent or soon-to-be PhD graduate who wants to work with #yeastdisplay, deep sequencing, #proteinexpression, #biophysicalcharacterization, #antibodyvalidation, #confocalmicroscopy, #AI, #ML or #automation? Apply to be an IPI #postdoc! buff.ly/jvpT6MP

Happy thanksgiving from IPI! We’re feeling especially grateful this week for our team and the many scientists, collaborators and partners who share our passion for advancing protein science. Your curiosity drives progress — and inspires us every day 🍂🧬

Congrats to IPI postdoctoral fellow Nirakar Basnet for co-authoring a recent paper @natcomms.nature.com with former colleagues at the Mizuno Lab. They resolved the #cryoEM structure of #SSNA-1, providing a detailed look at its self-assembly and role in #embryonicdevelopment ➡️

Scientists are drawn to their #research for all sorts of reasons, big and small. “What drives my science,” says IPI scientist Alex Morano, “is profound love of humanity and a desire to make the world better and safer for people.” Learn more about IPI’s story: buff.ly/ifaeFo9 #whatdrivesmyscience

There’s some exciting work happening w/ #neuroscience & #antibodies—PRISM barcoding, #synaptome mapping w/ ExA-SPIM, #wholebraintissueclearing and more. Huge thanks to the speakers who shared this work at a recent IPI meeting down the road (harbor? 🚢) from #SfN2025. Read more: buff.ly/Utn94ct

Come work with us! IPI is seeking a #postdoctoralfellow to join us and apply our #antibodydiscovery platforms to cutting-edge questions in #cellsurface #proteinresearch and #antibodyengineering. It could be you! Learn how to apply today: buff.ly/f2cLV4D

🛑 Are you using glypican antibodies to study brain development, neurodegeneration, cancer biology or cell signaling? 🛑 IPI has recombinant antibodies to GPC1-6 and we want you to know about them! So, what’s amazing about our anti-glypicans?

We had such a great time yesterday diving into cell-cell communication and the latest advances in molecular neuroscience on a rainy San Diego day! #SfN2025

New recombinant monoclonal antibodies from @ipiproteins.bsky.social at Addgene targeting Neurexin and Neuroligin — key mediators of synaptic adhesion and function. Explore the collection and advance your neuroscience research: https://twp.ai/4itA72 #neuroscience #neuroskyence

🚨IPI just released new antibodies into the @addgene.bsky.social catalog targeting Neurexin 1/2/3 & Neuroligin 1. Order now! buff.ly/CpP2b8x #ProteinScience #Neuroscience #Antibodies

IPI #researchassociate Minh Anh Kieu helps build and optimize our high-throughput antibody production pipeline — perfect for a problem-solver like her. Find out more about #antibodyproduction at IPI and stay tuned for what drives our science! buff.ly/V4wps8X #proteinscience #proteomics #bioscience