What would you do with unlimited DNA? Our CEO and co-founder Emily Leproust shares her thoughts in our latest blog post: “Changing How We Explore Sequence Space In The AI Era.” Read it here: www.twistbioscience.com/blog/perspec... @twistbioscience.com

Cheers to a new year! 🥂 As we ring in 2026, we’re grateful for our customers, collaborators, and colleagues who are changing the world. We can’t wait to see what 2026 will bring. 🧬 @twistbioscience.com

💥 Ending 2025 with a bang! We have a fantastic newsletter for you to round out the year! There is something for everyone in this newsletter: biosecurity, synthetic biology, new product highlight, collaboration information, and even a “chemistree” 🎄 @twistbioscience.com

Twisters volunteered at Buri Buri Elem. School doing cultural crafts with students in an after school program. We made a Filipino Parol craft and a Kwanzaa Kinara craft, and had a blast! Thanks to @lifesciencecares.bsky.social who organized the event and to the Twisters who volunteered their time.

Super excited about our 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕 pipeline being highlighted as one of @twistbioscience.com favourite publications of 2025! We did synthesize all binder genes with Twist ❤️

✨6 ✨ of our favorite groundbreaking publications from 2025, as curated by Twisters! Check them out below…

Reading roundup! Take a look at our 4️⃣ most popular blogs of 2025! 📚 *or hit that bookmark to save this post for reading during your holiday travel or if you need an excuse to sneak off to “work.”

✨ Merry Twistmas! ✨ Thank you to our customers, collaborators, and colleagues for a great year. Wishing you a happy, healthy holiday season from all of us at Twist. @twistbioscience.com

Our Boston team recently spent time volunteering at the South Shore YMCA’s North Pole event, helping bring some extra holiday magic to local families and kids in our community. Thank to Twisters Niall Higgins, Shaun Josephs and Manal Mrani for leading the east coast effort.

Codebreaker Labs Utilizes Twist’s Oligo Pools for Advanced Causal Genomics Screening to Enhance Drug Development and Diagnostics. Read our case study: From Observational to Mechanistic Genomics- Causal Genomics for Scalable Variant Interpretation www.twistbioscience.com/node/57886/p...

Twist elves are dropping holiday cheer at campuses near you! Reach out to your Twist rep if you want to be included in the fun! @twistbioscience.com

Only 9 days remain to snag some of our world famous Twist gear! Turn Up the Volume on Year-End Science! Rock new Twist & Shout gear in the lab or unwind with Bose speakers, these gifts are designed to elevate your research experience, and your style: www.twistbioscience.com/promo/twista...

Twisters spent time volunteering at the Women’s Resource Center (WRC) thrift store near our Carlsbad office. It was a hands-on way to support an organization that provides critical resources & services to individuals & families in our community. Thank you to the WRC team!

On-Demand Webinar: Using Plant Synthetic Biology for Sustainable, High-Yield Rubber Production 🌱 Hear from @igemhq.bsky.social ‘24 winners Julia Rinn & Alexander Kuhne (Master’s students, Philipps-University Marburg) as they share their award-winning project: www.twistbioscience.com/resources/we...

Big milestone for the AI Protein Design Program last November: our first AI binder design workshop! Proud of the team and grateful to @kmichie.bsky.social for her amazing talk. This is just the beginning… excited for what’s next! #AI #ProteinDesign #AIPDP

🤩 Wow #AET2025, what a turnout! Thanks to everyone who packed the house to hear Colby Souders’ talk “Scaling Machine Learning in Biologics: Leveraging High-Throughput Data for Next-Gen Biotherapeutic Discovery.” @twistbioscience.com #AntibodyEngineering

Reading roundup! Some of the most recent impactful papers all in one spot. Here are ✨4✨ papers you’ll want to know about…

When your delivery doubles as lab décor! 🎄 We are loving this picture that Genesis Genomics sent over of their clever holiday decor featuring our boxes! Complete with an eppendorf star, rudolf, and tip box presents. Thank you Genesis, and Merry Twistmas to all. @twistbioscience.com

🤩 🎉 We’re thrilled to see our collaboration highlighting the importance of iterative improvement, cross industry collaboration, and foresight in biosecurity screening in the age of AI with @microsoft.com in this list: news.microsoft.com/source/featu... @twistbioscience.com, @jdiggans.bsky.social

We have been busy! While it’s true 2025 is winding down, Twisters haven’t slowed down yet… From Pitchfest at @yalepress.bsky.social to #CellBio2025 in Philly, & the Univ. of Michigan Advanced Genomics Core Holiday Show, the teams have loved meeting YOU & hearing about your research!

Our world famous end-of-year promo has arrived… Turn Up the Volume on Year-End Science! Rock new Twist & Shout gear in the lab or unwind with Bose speakers, these gifts are designed to elevate your research experience, & your style: www.twistbioscience.com/promo/twista... @twistbioscience.com

🦙 It’s National Llama Day! Why is that thrilling, you ask? Llamas are the unofficial mascots here at Twist. In addition to being a petting zoo favorite, they also generate antibodies that can be developed into drug candidates for cancers, autoimmune diseases & viral diseases.

‘Tis the season to ✨ synthesize ✨ some cheer. We’ve added a little sparkle around the office and seeing the decorations go up has added a cheery spot as we wrap up the year. Happy holidays from the Twist team! @twistbioscience.com

Anyone else already missing PEGS? Massive thank you to all who shared their research with us in the booth, at our mixer (with ~200 people! 🤩), after our symposium and during the poster session. Your work inspires us! @twistbioscience.com

New product alert! Today we are launching research-grade Plasmid DNA Preps. 🧬 Designed to support the advancement of pharmaceutical and biotech customers’ pre-clinical studies: investors.twistbioscience.com/news-release... @twistbioscience.com

Strategic moves today help us support the thousands of customers transforming diagnostics, ag, and research. Thank to Ron Leuty for featuring us in this San Francisco Business Journal article here: www.bizjournals.com/sanfrancisco...

🤩 So exciting! iGEM is on 60 minutes! Watch the story of one team using CRISPR to detect Lyme disease. Just after the 15 minute mark: m.youtube.com/watch?v=MDWl... @igemhq.bsky.social, @igemcommunity.bsky.social, @60minutes.bsky.social 👀 Check out what we spotted during the episode👇

@twistbioscience.com is proud to sponsor Yale University’s Life Sciences Pitchfest where teams present their projects in 5-minute pitches to qualify as semifinalists for The Blavatnik Fund for Innovation at Yale: ventures.yale.edu/community/ya...

✨ One sleep to go until #CoESB25! ✨ We'd like to acknowledge the support from our valued sponsors: 💎 Diamond Welcome Dinner 🍽️ and Poster Sessions 🪧 Australian Genome Foundry and IDEA Bio 🏆 Gold Barista Coffee Cart ☕ @twistbioscience.com and Decode Science 🪩 Silver Shimadzu Tecan

A strong EU Biotech Act is essential for Europe’s synthetic biology community. As highlighted in our recent Science|Business viewpoint, harmonized DNA screening standards & clear EU-wide regulations will strengthen biosecurity and support responsible innovation: sciencebusiness.net/viewpoint/bi...

🍂 Happy Thanksgiving from all of us at @twistbioscience.com! We’re stuffed with gratitude for our customers, collaborators, and community.

Reading roundup! Some of the most recent impactful papers all in one spot. Here are ✨6✨ papers you’ll want to know about: From David R Liu and team: “Prime editing-installed suppressor tRNAs for disease-agnostic genome editing.” www.nature.com/articles/s41...

💡Curious about what else you can do with Oligo Pools? Whether you're new to Oligo Pools or looking to hear how other scientists are getting more out of their experiments, we’ve got a webinar for you. Explore on-demand sessions here👇 www.twistbioscience.com/resources/we... @twistbioscience.com

Whether you’re working, on vacation, or traveling today, we’ve got you! We’re highlighting @igemhq.bsky.social (the world’s coolest synthetic biology competition), customer papers, one of our most popular webinars and more:

Cloning? Bold choice. Twist, better choice. @twistbioscience.com

Open-source but make it bio! David Baker’s lab has developed AI designed antibodies from scratch, and they are available on GitHub. 🤩 Read the @geekwire.com article here: www.geekwire.com/2025/nobel-w...

Twist & Shout! Our world famous end-of-year promo has arrived… Whether it’s rocking your new Twist & Shout gear in the lab or unwinding with your Bose speakers, these gifts are designed to elevate your research experience & your style: www.twistbioscience.com/promo/twista... @twistbioscience.com

We’re inspired by a recent WEHI-led study that has the potential to transform how ovarian cancer is treated. Read the article here: www.wehi.edu.au/news/blood-t... Read the Nature Communications paper here: www.nature.com/articles/s41... @twistbioscience.com @wehi-research.bsky.social

It’s not goodbye, it’s see you later! Until next year AMP 👋 The Twist team had the best time at AMP 2025 in Boston! Thank you to all who came by the booth and to our talk, your insightful questions and hearing about your research inspires us. @ampath.bsky.social #AMP2025 @twistbioscience.com

That’s a wrap on PEGS 2025 in Lisbon! Massive thank you to all who shared their research with us in the booth, at our mixer (with over 200 people! 🤩), after our symposium and during the poster session. Your work inspires us! @twistbioscience.com #PEGS2025 #PEGSEurope

Agrigenomics, accelerated: @twistbioscience.com + Curio Genomics teamed up to deliver: ✅ Fast, scalable workflows ✅ Real-time variant calling & QC ✅ Integrated microarray + NGS data Learn more in our latest app note: www.twistbioscience.com/sites/defaul...

One of our most popular webinars is now on demand! 🎥 Belgium’s BabyDetect Project screened newborns for 165 treatable conditions using deep sequencing with >90% of 6K+ families participating. Prof. François Boemer shares insights: m.youtube.com/watch?v=zNGz... Paper: www.nature.com/articles/s41...

We have ✨four✨ important papers to share with you today from Twist customers! From a breakthrough in lung cancer monitoring to generating long deletions across the genome, browse the papers below from @sangerinstitute.bsky.social, Francis Crick Institute, @ucl.ac.uk, @uwproteindesign.bsky.social👇

Microsoft has a fabulous behind-the-science blog paraphrasing the Paraphrase Project. 😉 @erichorvitz.bsky.social, Bruce Wittmann, Tessa Alexanian, and our own @jdiggans.bsky.social are thinking about the latest threats to biosecurity so you don’t have to...

Coming up! Rewriting Cancer’s Script: Insights from Saturation Genome Editing 🗓️ 25 November 2025 4 PM CET | 7 AM PST @twistbioscience.com #Webinar with @davidjadams.bsky.social @sangerinstitute.bsky.social Register for this free webinar here: tinyurl.com/RewritingCan...

🧠 Ready to put your STEM smarts to the test? We’re celebrating #STEMDay with a crossword puzzle containing clues from science, tech, engineering & math. Print it out, grab a pencil, & get ready for a little office/lab competition! 🤫 Key in the comments. @twistbioscience.com

In this blog, we explore how a uniform DNA library can save researchers time, money, & effort while ⬆️ hits in experiments. Spoiler: Twist’s precision makes a big difference. 😉 Check out how better DNA uniformity leads to better research outcomes: www.twistbioscience.com/blog/science...

Then we scaled up. Using improved long oligo synthesis (@twistbioscience.com), we encoded both pegRNAs in a single construct, enabling true pooled paired prime editing. We designed 10,471 deletions across 149 genes using the PE7 system from Britt Adamson's lab.

Our inaugural Biopharma Antibody Discovery Meetup in Utrecht was a huge success! Thank you to everyone who attended, sharing ideas, and inspiring the community. Keep an eye on our feeds for the next stop in this series: the Nordics and UK!

Customer spotlight & new tool for your toolbox! The @sstevenwang.bsky.social lab introduces RAEFISH, enabling sequencing-free whole genome spatial transcriptomics at single molecule resolution. 🎉Thank you for choosing Twist Oligo Pools to support this exciting work: www.cell.com/cell/fulltex...