One of the hallmarks of #Alzheimer’s disease is the clumping of proteins called Tau. @mit.edu#Alzheimerchemists have now shown, for the first time, that NMR spectroscopy can decipher the structure of the fuzzy coat on #Tau that facilities clumping: https://bit.ly/49pUoJu

What goes into planning the world's largest all-immunology event? Join AAI President Dr. Uli von Andrian and Program Chair Dr. Shekhar Pasare for a preview of #IMMUNOLOGY2026™! 🧬 Presidential Symposium 🔬 Special Sessions 🎓 Trainee Programs 🔗 immunology2026.aai.org

🧫 @harvardmed.bsky.social researchers have uncovered crucial insights into how an emerging class of #antiviral drugs works. The discovery from the Abraham lab sheds light on an important tool for fighting drug-resistant strains of herpes simplex virus: https://bit.ly/4jLKEge

Three cheers for C. elegans! 🪱 In a perspective piece, biologists including Dr. Robert Horvitz at @mit.edu celebrate Nobel Prize-winning advances made through research in #Celegans. Read about the powerful discoveries uncovered by worm science: https://bit.ly/3LFbMRj

The 4D Nucleome Consortium has extensively mapped and analyzed the three-dimensional folding of the #HumanGenome in human embryonic stem cells and immortalized fibroblasts over time. The Consortium is led by Dr. Job Dekker at @umasschan.bsky.social#HumanGenome https://bit.ly/3NhIIQs

The @whiteheadinstitute.bsky.social has welcomed Dr. @zurisullivan.bsky.social as its newest member! Dr. Sullivan is an #immunologist who studies how the immune system communicates with the brain to shape behavior during infection. 👁️Keep an eye out for her lab's future work! https://bit.ly/4pB0TOq

About 48.5 million couples worldwide experience difficulty conceiving children. While treatments like IVF are becoming increasingly popular, it's also expensive, traumatic for a woman's body, and not guaranteed to work. Gameto is using the Wyss' ovarian organoid technology to help.

🤯 A new ‘biomimetic’ model of brain circuits and function showed naturalistic dynamics and learning. The model, co-created by Dr. @earlkmiller.bsky.social at the @picowerinstitute.bsky.social, identified previously unnoticed curious behavior by some neurons: https://bit.ly/49rQoXp

A recent study by the Laboratory for Neuro-Analysis and Imaging at @umasschan.bsky.social highlights how subcortical brain structures degenerate in #Alzheimer’s disease and frontotemporal #dementia patients. See the work from Dr. Manojkumar Saranathan and Arit Banerjee: https://bit.ly/3NaVDn5

New findings from Dr. Mirco Friedrich and the Zhang lab at @mit.edu showed that the liver can be transiently repurposed to restore age-diminished immune cues and improve #TCell function in aged mice: https://go.nature.com/4p6rD8Z

Researchers led by Dr. Jessica Stark (@jcstark.bsky.social) have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make #CancerImmunotherapy work for many more patients. 📰 MIT News: https://bit.ly/3YlpCeq

New year, new experiments… and maybe some new habits too! Kick off 2026 with Lab Coats and Life, the podcast that helps scientists navigate the human side of research. If your resolutions include more balance, purpose, and curiosity, this is the perfect place to start. 🎧 https://bit.ly/4pTHNnx

🎇 Happy New Year from Science in Boston! Here’s to another year of discoveries that expand our understanding, collaborations that bring ideas to life, and communities that make science stronger, brighter, and more connected. 🎉

🥇 Counting down to our #1 post of 2025… and here it is! Drs. Ramnik Xavier and Christopher Smillie at the @broadinstitute.org mapped cellular location and gene activity to understand Crohn’s disease at unprecedented resolution. https://bsky.app/profile/scienceinboston.com/post/3ltftlcyyis2z

Our #2 spot tackles global preparedness. 🌎 2025 saw the Sentinel project at @broadinstitute.org funded for the next five years to detect outbreaks in real time and stop pandemics before they start! https://bsky.app/profile/scienceinboston.com/post/3m6i4f2bgsy2u

🧫 Our #3 post celebrates a huge step in Ebola research. Congratulations to the Blainey and Davey labs at @mit.edu and @bumedicine.bsky.social who uncovered 998 host regulators of Ebola infection this year! https://bsky.app/profile/scienceinboston.com/post/3lvcb3x7zuk22

Coming in at #4 in our Top 5 Countdown: virus hunters assemble! Dr. @shiraweingarten.bsky.social at @harvardmed.bsky.social launched the Laboratory of Systems Virology. We cannot wait to see what the lab accomplishes in 2026! https://bsky.app/profile/scienceinboston.com/post/3lsuek25o5c2f

Starting our Top 5 Countdown with #5, we want to congratulate the Bryson Lab (@ragoninstitute.bsky.social) and their roadmap for developing better tuberculosis vaccines! Congratulations! 💉 https://bsky.app/profile/scienceinboston.com/post/3m5wwqvoan523

Ready for the science highlight reel of the year? 🤓 🧪 Welcome to the Science in Boston Top 5 Post Countdown, showcasing the most community-loved posts of 2025. Get ready for jaw-dropping discoveries and the people who made it all possible! Check back tomorrow for #5...

❄️☃️ Looking for something insightful to listen to over the holidays? Explore the @immunologypodcast.com! Whether you're traveling or unwinding at home, it’s the ideal companion for curious minds. 🎧 https://bit.ly/47nGZAG

🎧 As the year winds down, it’s the perfect time to recharge your curiosity. Explore the @stemcellpodcast.com, where experts share insights on stem cell biology, new technologies, and the future of regenerative medicine. 🎄 Add it to your holiday playlist: https://bit.ly/4pJa6VA

Our website is taking a short holiday break while we recharge for 2026. But don’t worry, the science doesn’t stop! Keep an eye on our socials over the holidays for community highlights, Top 5 countdowns, and plenty of good science stories to carry you into the new year. See you in January! ❄️🔬

Dr. Sara Tolaney at @danafarber.bsky.social is the recipient of the 2025 @theaacr.bsky.social Outstanding Investigator Award for Breast Cancer Research. This award honors investigators whose work has left an impact on study of #BreastCancer. 🎉 Congratulations! https://bit.ly/3MNKvfz

Scientists at @harvardmed.bsky.social uncovered new genetic details of #FriedreichsAtaxia, a devastating neurodegenerative disorder that does not yet have a cure. Drs. Vamsi Mootha and Joshua Meisel described a genetic modifier that enables cells to survive without frataxin: https://bit.ly/4pH0NWj

Dr. Xueyang Dong, a postdoctoral researcher in the Nagashima lab at @harvardmcb.bsky.social , has been selected for a prestigious Cancer Research Institute Postdoctoral Fellowship. He will be working to uncover how the immune system recognizes #GutBacteria. Congratulations! https://bit.ly/48VJfyl

Our most popular interview of 2025. @robertwaldinger.bsky.social leads the Harvard Study on Adult Development, one of the longest-running scientific investigations into human wellbeing. Earlier this year, he sat down with us to discuss the secret to happiness: hvrdct.me/2a2c97

A personalized biomaterial #CancerVaccine just passed its first-in-human test! Started by Drs. Stephen Hodi & David Mooney's labs at the @wyssinstitute.bsky.social#CancerVaccinein 2013, the trial showed that the system can be consistently fabricated and applied to patients: https://bit.ly/3KPfHe0

Drs. Lina Marcela Carmona and Nils Grotehans from @umasschan.bsky.social has received awards from the American Federation for Aging Research and the Glenn Foundation. Congratulations to both researchers! https://bit.ly/3MuZoDA

We're having a great time at the Boston ISSCR PSC-Derived Therapies Symposium, but the fun isn't over! 🤩 Remember to stop by booth #18 for a chance to win a prize and chat with our team!

Thanks to everyone who attended our Innovation Showcase by Dr. Andrew Gaffney and Dr. Janet Rothberg from CCRM! 👋 See you tomorrow for Day 2 of the Boston ISSCR PSC-Derived Therapies Symposium!

The ISSCR PSC-Derived Therapies Symposium is buzzing already! 🤩 What's in store for today? Starting with an Innovation Showcase at 2 pm, check out Dr. Andrew Gaffney's talk! Come check out Kimberly Snyder's work: 📍Poster #117 at Poster Session 1 ODD 📍Poster #158 at Poster Session 2 EVEN

Glioblastoma is the most common form of brain cancer in adults, and its usually quick and fatal. A study from the @mitkochinstitute.bsky.social profiling antigens presented on immune and tumor cells in co-culture points to new strategies for attacking #glioblastoma: https://bit.ly/4aGcO9E

Online & self-paced course designed for healthcare professionals, researchers, & medical students who are interested in learning more about genomic medicine. ⁠Free for Harvard affiliates & open to others for a fee: hvrdct.me/19a7ba

🚨 @mit.edu postdoc Dr. Arianna Bresci is the lead author of a new study that shows researchers can accurately measure blood glucose by shining near-infrared light on the skin. This noninvasive imaging could replace finger pricks for people with #diabetes: https://bit.ly/48XasC5

A new study from researchers at @bumedicine.bsky.social shows that a treatment made up of #ExtracellularVesicles released by stem cells in bone marrow can slow and even reverse certain aspects of normal age-related #MemoryDecline. Learn more: https://bit.ly/4oKIKx4

Dr. Naoshige Uchida at @harvardmcb.bsky.social was named the Jeff C.Tarr Professor of Molecular and Cellular Biology! 🧠 Dr. @naoshigeuchida.bsky.social is a leading neuroscientist whose work has reshaped our understanding of learning, decision-making, and sensory processing: https://bit.ly/4rurte6

✂️ #CRISPR research by Dr. George Church @geochurch.bsky.social inactivated all 62 copies of porcine endogenous retrovirus. 🐖 Now, eGenesis at @wyssinstitute.bsky.social & @harvardmed.bsky.social#CRISPRbuilds upon this work to develop safe pig organs for #xenotransplantation: https://bit.ly/4iAZKV7

@aai.org invites you to submit abstracts of unpublished, original research for presentation at #IMMUNOLOGY2026™. This dynamic opportunity to showcase your research empowers you to connect, collaborate, advance your career, and access cutting-edge research. Submit & save today! https://bit.ly/48cjOtl

Wyss startup Unravel Biosciences is now a clinical-stage therapeutics company! The Colombian Health Regulatory Agency, INVIMA, approved their RVL-001 clinical trial for Rett syndrome and Pitt-Hopkins syndrome. They've started enrolling patients and expect the trial to begin in January 2026.

Drs. Matthew Meyerson and Heidi Greulich from the @broadinstitute.org sit down and discuss how they and Bayer scientists developed the first FDA-approved #CancerDrug to come from a Broad scientific discovery. 🤝 Learn more about their academic-industry alliance: https://bit.ly/4ruQNRl

Nine Wyss Faculty and staff members made the Highly Cited Researchers 2025 list, which honors the top 1% of researchers around the world whose papers have been cited the most over the last decade. We're so proud of their significant influence in their fields and impact on society. bit.ly/4aqYS3c

After an extensive analysis by scientists at @mit.edu 's McGovern Institute, neuroscientists now have an atlas detailing #astrocytes’ dynamic diversity. 🗺️ Check out the work from Dr. Guoping Feng's lab. 👇 In the news: https://bit.ly/3MwwDWS In @cellpress.bsky.social#astrocytesNeuron: https://bit.ly/3XtLDY6

"I don't think you make disruptive advances by just following linear paths in your own field," explains Don Ingber. In this episode of Talking About Blood, he discusses organ chips, their applications, and his transdisciplinary career journey.

We’re thrilled to be part of the #ISSCR2025 Boston International Symposium in less than two weeks! Get prepped by listening to Dr. Stefan Irion, one of the symposium organizers, sit down with our friends at the @stemcellpodcast.com#ISSCR2025: https://bit.ly/49B11cp

🥳 @harvardmcb.bsky.social postdoc Dr. Rebecka Sepela has been selected as one of the 2025 L’Oréal USA For #WomenInScience Fellows. This prestigious honor recognizes early-career scientists whose research, mentoring, and outreach efforts are shaping the future of STEM: https://bit.ly/48dvLh5

The Earth is in crisis, and we need solutions. The Wyss' Sustainable Futures Initiative is tackling this Grand Challenge by re-designing the systems we rely on, from farming to materials and manufacturing, to become planet-friendly with high-performance and scalable features.

🤓 New tech alert! 3DModeler is a new software program developed by Dr. Ata Kiapour and colleagues at @bostonchildrens.bsky.social . It uses 3D imaging and AI to support the diagnosis and treatment of hip conditions: https://on.bchil.org/44wYDjj #Orthopedics

Jacqueline Garcia, MD, is exploring ongoing clinical research to test novel triplet therapies for safety and efficacy with a precision medicine approach for patients with acute myeloid leukemia. Explore the latest updates: bit.ly/3LmZEUC

The John D. and Catherine T. MacArthur Foundation has awarded a $100 million, 5-year grant to the Sentinel project at @broadinstitute.org. 😷 Drs. Christian Happi & Pardis Sabeti will create a system to detect outbreaks in real time, preventing them from becoming pandemics: https://bit.ly/483My7H

Are you heading to the #ISSCR2025 Boston International Symposium on December 11–12? 👋 Come say hello to our team and learn how we’re supporting innovation in stem cell science. Stay tuned for details on where to find us, what we’ll be presenting, and how you can engage with us.