🪩 Dr. Joshua Sanes from @harvardmcb.bsky.social has been awarded the 2025 Ralph W. Gerard Prize in Neuroscience from the Society for Neuroscience. The Gerard Prize, the society’s most prestigious honor, recognizes lifetime achievement in neuroscience: https://bit.ly/3WP91iq

During Pancreatic Cancer Awareness Month, we’re highlighting new research from Dana-Farber, @mit.edu, and the @broadinstitute.org revealing potential new ways to harness the immune system against pancreatic cancer. Learn more: bit.ly/3Wt0qBN

💊 @mit.edu researchers in the Hammond and Irvine labs have designed nanoparticles that deliver an immune-stimulating molecule, IL-12, directly to #OvarianTumors. When given along with checkpoint inhibitors, IL-12 helps the immune system attack cancer cells: https://bit.ly/4ozbI3U

Investigators at @umasschan.bsky.social received a $6.6 million grant from the NIH to evaluate potential gene editing technologies to correct granulin mutations. Congratulations Drs. Scot Wolfe, Fen-Biao Gao, Erik Sontheimer, and Jonathan Watts: https://bit.ly/43TnHAJ

A new study, led by the Kwon Lab ( @ragoninstitute.bsky.social ) and Xavier Lab ( @broadinstitute.org ), shows that HIV infection and common antiretroviral drugs change the gut microbiome in distinct, geography-dependent ways. 📰: https://bit.ly/4qCw0ux 📝 Nature: https://go.nature.com/4nzH7ld

A new @ragoninstitute.bsky.social study shows that a single mRNA-based vaccine mix can jump-start the early steps toward several promising HIV-fighting antibodies at the same time. Learn more about the work from Drs. Xuesong Wang, Zhenfei Xie, and Yu Yan in the Batista lab: https://bit.ly/3WExxmd

Happy Halloween! 🎃🦇 Bats are more than just Halloween icons — HHMI scientists are studying them to explore fundamental questions about the brain & behavior. Their discoveries could have important implications for other species, including humans. Read more: bit.ly/434gm18

Halloween in the lab means swapping pipettes for pumpkins (but maybe not at the same time). Whether you’re running gels or running from ghosts, we wish everyone a frightfully fun and scientifically sound Halloween! 👩‍🔬🧛‍♀️ 🎃 Happy Halloween!

🎙️ This week's episode of the @stemcellpodcast.com features Dr. Juan Melero‑Martin ( @meleromartinlab.bsky.social ) from @bostonchildrens.bsky.social! Dive into the conversation where he explores how vascular networks form and influence stem-cell engraftment. 🎧 Listen now: https://bit.ly/3Lg37UX

Stay ahead of Boston's science scene! Subscribe to the Science in Boston newsletter for and never miss out on: 📰 The latest research news & publications 🎟️ Upcoming science events 💼 Local job listings Be part of the community driving science forward: https://bit.ly/48SnO38

#Bioreactors are key for #CellCulture, but tend to land in a sticky situation: Adherence! 🫧 The Varanasi lab at @mit.edu#Bioreactors#CellCultureas developed an approach for detaching cells from surfaces on demand using electrochemically generated bubbles. News: https://bit.ly/4oFJ3tk Abstract: https://bit.ly/434wxeN

Dr. Stephanie Carreiro from @umasschan.bsky.social has received a Midcareer Investigator Award in Patient-Oriented Research from the National Institute on Drug Abuse. She will use this award to advance #PrecisionMedicine for opioid use disorder and mentor emerging scientists: https://bit.ly/47tmUYe

"What mattered, I realized, was not to be some imaginary perfect mentor with all the answers, but to get to know my mentee ... and offer whatever guidance and support I could based on my own experiences." #NationalMentoringDay https://scim.ag/47mSs29

Dr. Charles Park, a postdoctoral researcher in the Mitagotri lab at the @wyssinstitute.bsky.social , has been named a 2025 STAT Wunderkind by STAT News! Dr. Park’s work focuses on reprogramming #macrophages to take on #AntiCancer phenotypes. 👏 Congratulations! https://bit.ly/4oAT1w9

A new 3D human brain tissue platform developed by the Tsai and Langer labs at @mit.edu is the first to integrate all major brain cell types, including neurons, glial cells, and the vasculature into a single culture. 🗞️ Press release: https://bit.ly/3WV1mPi 🧠 Abstract in PNAS: https://bit.ly/48NAlot

New work from Dr. Shamil Sunyaev at @harvard.edu shows that as men age, harmful genetic mutations in #sperm not only accumulate but are favored during sperm production, giving them a reproductive advantage. 📑 Nature study: https://go.nature.com/3WCZ736 🎙️ Podcast episode: https://bit.ly/4qfiME4

Congratulations Dr. Wilfredo Garcia-Beltran from the @ragoninstitute.bsky.social on receiving a NIH High-Risk, High-Reward Research Program award! This grant will support a new project that retools #NaturalKiller cells to better locate, enter, and destroy solid tumors: https://bit.ly/4nZMWcG

"The germline is the only cell type responsible for transmitting the genome from generation to generation," @whiteheadinstitute.bsky.social 's Dr. Yukiko Yamashita says. ⏳ Learn about how the Yamashita lab is teasing apart how the #germline remains immortal! https://bit.ly/42QARy3

💡 @mit.edu engineers have designed a new control mechanism that allows them to establish a desired protein level for any gene circuit. This approach also allows them to edit the set point after the circuit is delivered. Learn more about the work from the Galloway lab: https://bit.ly/48zqzWJ

Dr. Alison Ringel from the @ragoninstitute.bsky.social has been awarded a prestigious grant from the W.M. Keck Foundation! Dr. Ringel aims create a more comprehensive biomedical understanding of the cause and possible treatments for aging-related decline. 🥳 https://bit.ly/499nxsv

🚨 @mit.edu chemists have designed a new type of fluorescent molecule that they hope could be used for applications such as generating clearer images of tumors. Learn more about the new, borenium ion-based dye: https://bit.ly/47tfxkP #FluorescentMicroscopy

Dr. Philip Kranzusch, Professor of Cancer Immunology and Virology at @danafarber.bsky.social, was one of three scientists awarded top honors at the 2025 Blavatnik National Awards for Young Scientists, a significant prize for early-career researchers. Congrats Dr. Kranzusch! https://bit.ly/3LcWgvd

Congratulations to Paul Richardson, MD, recognized by the Lymphoma, Leukemia, & Myeloma Congress with the Joseph Michaeli Award for Outstanding Contributions to Myeloma. His leadership helped introduce cornerstone treatments for multiple myeloma, each of which has kept the field at the cutting edge.

🏆 Big news in melanoma research! Dr. Richard Gregory at @umasschan.bsky.social has secured a $4.4 million, 5-year grant from the National Cancer Institute to study how tRNAs may drive #melanoma metastasis. Congratulations to Dr. Gregory and colleagues: https://bit.ly/3KNLZpk

What causes dormant cancer cells to erupt into a frenzy of growth and division? New work from the Weinberg lab points to inflammation as a trigger. wi.mit.edu/news/inflamm...

How does acidity affect #ImmuneCells? The @xuzhoulab.bsky.social at @bostonchildrens.bsky.social found that a drop in pH can suppress immune responses by disrupting a protein called #BRD4. 🥼 Abstract in @cellpress.bsky.social#ImmuneCells#BRD4https://bit.ly/3IZDAhP ✏️ Press release: https://on.bchil.org/48rhZtf

A prestigious grant from the W.M. Keck Foundation to Ragon Core Member Alison Ringel, PhD, will support groundbreaking healthy aging research at MIT. Read more: https://biology.mit.edu/w-m-keck-foundation-to-support-research-on-healthy-aging-at-mit/

Drs. Fuguo Liu and Jianzhu Chen at the @mitkochinstitute.bsky.social have made a new way to engineer CAR-NK cells that makes them much less likely to be rejected by the patient’s #ImmuneSystem. Learn how this aids the development of “off-the-shelf” CAR-NK cells: https://bit.ly/3KIOPf9

Dr. Travis Rotterman, a @bumedicine.bsky.social Assistant Professor of Pharmacology, Physiology, and Biophysics, has been named one of this year’s Boston University Career Development Professors. 👏 Congratulations Dr. Rotterman! https://bit.ly/4q2JdMR

Researchers at the Wyss have developed DNA Nanoswitch Calipers, a method for identifying and measuring post-translational modifications on proteins, which could unlock profound advances in our understanding of health and disease, as well as biomedicine. #NanoDay

RNA Structure beyond Canonical Base Pairs Guided by Evolution 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @rivaselenarivas.bsky.social @rachellegaudet.bsky.social @cryptogenomicon.bsky.social @dulaclab.bsky.social @neurovenki.bsky.social @naoshigeuchida.bsky.social

A new paper by @ragoninstitute.bsky.social biostatisticians in the Ghebremichael Lab introduces and tests a flexible way to grade medical tests like blood-based #biomarkers so scientists can more confidently tell which ones truly separate “sick” from “healthy.” Learn more: https://bit.ly/4pTUDT7

The #scientifyRESEARCH #SciComm Award returns, this year highlighting rare disease research! Researchers: Translate your peer-reviewed work for the public. Sign up for updates: www.scientifyresearch.org/rare-disease... Partner or sponsor? Contact us: [email protected] #RareDisease

Dr. Ryan Logan at @umasschan.bsky.social is a principal investigator on three NIH grants, totaling nearly $10 million in research support for his work investigating the underlying biology of #OpioidUseDisorder. Congratulations! https://bit.ly/438Sl8T

Free consulting service. NIH K grant applicants: Apply to receive tailored feedback on your draft Specific Aims page & attend a career development consult with a Harvard-affiliated distinguished mentor. Free for @harvard.edu affiliates. Apply: hvrdct.me/947b9d

Drs. Volker Hovestadt and Gabriel Griffin at @danafarber.bsky.social have developed a groundbreaking diagnostic tool, called MARLIN, that could transform the way acute #leukemia is identified and treated. ⚙️ Press release: https://bit.ly/4pUDBEt 🧪 Abstract: https://go.nature.com/48ea16t

🩸 The @wyssinstitute.bsky.social has received Wellcome Leap funding to develop the first-ever human Organ Chip model for heavy menstrual bleeding. This work led by Dr. Don Ingber could transform our understanding of #ReproductiveHealth and lead to better treatments. See more: https://bit.ly/3KBzcGe

Mucus contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection. In a new study, @mit.edu researchers have identified mucins that defend against #Salmonella and other bacteria that cause diarrhea 💩: https://bit.ly/4o30C6z

A new @cp-cellreports.bsky.social study from Drs. Andrea Papadopoulos & Zaza Ndhlovu at the @ragoninstitute.bsky.social explains how HIV survives in lymph nodes during treatment. They showed that the virus weakens nearby “killer” CD8 T cells from inside B cell follicles. 🕵️ https://bit.ly/48HI6vV

Researchers at @mit.edu have now found a way to dramatically lower the error rate of prime editing. This advance could make it easier to develop gene therapy treatments, according to Dr. Phillip Sharp, senior author of the study. 🧬 https://go.nature.com/4pvgksB 📰 https://bit.ly/4nEeIuI

👏 PhD candidate Jessica Peura from @umasschan.bsky.social earned a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship from the National Cancer Institute! Peura's research analyzes how cancer spreads: https://bit.ly/429HoDJ

🥽 New research from the Maus and Manguso labs at @harvardmed.bsky.social has identified genetic modifications that may increase the effectiveness of immunotherapy for #MultipleMyeloma, a difficult-to-treat blood cancer. Press release: https://bit.ly/3W6V3b0 Abstract: https://go.nature.com/3W6V2Uu

🍎 Two @harvardmcb.bsky.social educators have been recognized with the Anya Bernstein Bassett Award for Excellence in Teaching. This award celebrates outstanding non-ladder faculty who are primarily focused on teaching. Congratulations to Drs. Sien Verschave and Alain Viel! https://bit.ly/42HwfKn

Check out this article to see the highlighted work from Dr. George Church at @harvardmed.bsky.social and previous Boston researchers Drs. Timothy Lu and Jay Shendure!

📢 @umasschan.bsky.social has licensed worldwide rights to a long-lasting human monoclonal antibody that prevents #LymeDisease to Tonix Pharmaceuticals. 🔗 Learn more: https://bit.ly/42aiML8

A new study led by Dr. Upasana Das Adhikari, Dr. Douglas Kwon's lab, and collaborators shows how energy use by gut immune cells can weaken the intestinal lining in people living with #HIV, even when the virus is controlled by treatment. https://bit.ly/3Kh01zp

Drs. Vikash Chauhan, Phillip Sharp, and Robert Langer from @mit.edu have dramatically lowered the error rate of prime editing, a technique that holds potential for treating many #GeneticDisorders. 🥼 Abstract: https://go.nature.com/4pvgksB 🗞️ Press release: https://bit.ly/4nEeIuI

🧪 Cache DNA, a biotech out of @mit.edu, has developed technologies that preserve #biomolecules at room temperature. This will make storing and transporting samples less expensive and more reliable. Learn more from CEO Dr. James Banal: https://bit.ly/46b21BT

Bellono Lab Research Featured on Two September Cell Covers 🧠 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @nbellono.bsky.social @rachellegaudet.bsky.social @dulaclab.bsky.social @naoshigeuchida.bsky.social @zombiflied.bsky.social @microbiometcell.bsky.social @jeeyunc.bsky.social

"We're thinking about any way we can get this to patients. That's the whole point of what we're trying to do," explains Paul Stankey, a researcher in Core Faculty member Jennifer Lewis' lab. Learn what it will take to scale up their work and bring their technologies to patients.