One of the most-viewed PNAS articles in the last week is “Engineered 3D immuno-glial-neurovascular human miBrain model.” Explore the article here: https://ow.ly/q1U350XmIwf For more trending articles, visit https://ow.ly/sweo50XmIw6.

We’re proud to be part of this new @broadinstitute.org effort! In this Q&A Picower researchers Sara Prescott and Ravi Raju describe the project, how they’re involved, and the research they’re doing: picower.mit.edu/news/qa-pico...

To get back on track after a distraction, the brain appears to employ a rotating traveling wave, a new study by the lab of @earlkmiller.bsky.social finds. picower.mit.edu/news/after-d... @mitbcs.bsky.social #neuroscience #cognition

New research shows attention lapses due to sleep deprivation coincide with a flushing of fluid from the brain — a process that normally occurs during sleep. news.mit.edu/2025/your-br...

At our Fall Symposium, "Circuits of Survival and Homeostasis," seven speakers from around the country convened to describe some of the latest research on the neural mechanisms that we need to survive and thrive. picower.mit.edu/news/symposi... #neuroscience @mitbcs.bsky.social

📃Three late-onset #Alzheimers patients who received 40Hz sensory stimulation for ~2 years performed significantly better on several assessments than comparable AD patients outside MIT's clinical study of the potential therapy. picower.mit.edu/news/small-s... #neuroscience @mitbcs.bsky.social

Excited that an MIT-based team is one of 10 (out of ~200) to advance to the semi-finals! Learn about our project, FINGERPRINT: An agentic AI that will link discovery, prevention and therapy by reasoning across multiple biological and clinical data sets. picower.mit.edu/news/mit-bas...

New paper: Working memory readout varies with frontal theta rhythms. A theta traveling wave swept across the frontal cortex like radar, modulating performance of a working memory task. Because cognition is rhythmic. www.cell.com/neuron/abstr... #neuroscience @picowerinstitute.bsky.social

When spotting what’s changed from one scene to the next, performance will depend on a low-frequency “theta” brain wave that scans the mental image, a new MIT study in @cp-neuron.bsky.social shows. picower.mit.edu/news/radar-b... #neuroscience #cognition

Cultured from induced pluripotent stem cells, ‘miBrains’ integrate all major brain cell types and model brain structures, cellular interactions, activity, and pathological features. picower.mit.edu/news/mit-inv... #neuroscience

MIT neuroscientists show in a new study that loops of RNA can strongly influence how neurons build circuit connections, or synapses, during the development of the visual system in young mice. picower.mit.edu/news/study-f... #neuroscience @mitbcs.bsky.social

MIT scientists have discovered how neural activity helps brain circuit connections become tuned to the right size and degree of signal transmission in fruit fly models. picower.mit.edu/news/neural-... #neuroscience

🧠A week from today, join us at MIT for "Circuits of Survival and Homeostasis." It will be a fascinating day of talks about the links between body and brain. docs.google.com/forms/d/e/1F...

Our labs' studies have revealed a number of ways moods emerge in the brain and therefore are providing potential paths to address depression, PTSD, anxiety and bipolar disorder. Learn more in our Fall newsletter cover story. picower.mit.edu/news/many-me... #neuroscience #depression #anxiety #bipolar

Visually observing neural activity in freely moving animals requires identifying and tracking moving cells. In @elife.bsky.social the Flavell lab describes deep neural networks to enable this in a nematode worm (and applies some to jellyfish too!). elifesciences.org/reviewed-pre... #neuroscience

Congratulations to Linlin Fan on earning a BBRF Young Investigator grant! 'Using all-optical methods, Fan’s lab will study whether and how serotonin modulates plasticity. bbrfoundation.org/content/brai... #neuroscience #memory

Register now for "Circuits of Survival and Homeostasis" on 10/21! Seven talks will cover how brain-body circuits monitor, regulate, and repair fundamental physiological functions, offering insights into their mechanisms and potential therapeutic targets. docs.google.com/forms/d/e/1F... #neuroscience

Before a packed house, speakers at MIT’s Aging Brain Initiative symposium 9/18 described how immune system factors during aging contribute to #Alzheimers, #Parkinsons and other conditions. The field is leveraging that knowledge to develop new therapies. picower.mit.edu/news/immune-...

New paper! Evidence for an active handoff between hemispheres during target tracking www.jneurosci.org/content/earl... #neuroscience

As an object moves across your field of view, the brain seamlessly hands off visual processing from one hemisphere to the other like cell phone towers or relay racers do, a new study by @earlkmiller.bsky.social in @sfnjournals.bsky.social shows. picower.mit.edu/news/how-bra... #neuroscience

A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to the development of #Alzheimers in some of the people who carry it. picower.mit.edu/news/study-e... @mitbcs.bsky.social #neuroscience

🫁↔️🧠 A review by Sara Prescott's lab lays out the latest airway-brain circuits research and makes the case that "ongoing research promises new insights into airway disease mechanisms and the neural basis of breathing-related behaviors." www.sciencedirect.com/science/arti... #biology #neuroscience

How do neurons sense (or get tricked by) the bacteria in the microbiome? A new preprint from the lab of Steve Flavell led by Cassi Estrem identifies chemical cues that trigger neurons in C. elegans models. www.biorxiv.org/content/10.1... #neuroscience #microbiome @mitbcs.bsky.social

Excited (!) for our investigator Brady Weissbourd who will study how jellyfish larvae sense and use environmental cues to explore their world and decide where to settle, offering insights into marine population dynamics, invasive species control, and the neural basis of decisions in early life.

A sweeping study by MIT researchers shows the importance of understanding #Alzheimers disease as a battle over how well brain cells regulate the expression of their genes. picower.mit.edu/news/alzheim... #neuroscience #epigenomics @mitbcs.bsky.social @csail.mit.edu

Don't skip the textbook section!

In The Transmitter's reading list, we highlight the most anticipated upcoming neuroscience books and other notable 2025 releases. Featuring titles by @okaysteve.bsky.social, @dr-brein.bsky.social, @nicolecrust.bsky.social,‬ Xiao-Jing Wang and many more. By @franciscorr25.bsky.social bit.ly/45MvK41

🗓️If you are gonna be around Boston Sept. 18 and are interested in how the immune and nervous systems intersect in the context of brain aging, we've got an amazing day planned for you! Join us. Registration is open! picower.mit.edu/events/neuro... #neuroscience #alzheimers #aging #immunology

Inside the search for a universal signature of unconsciousness bigthink.com/neuropsych/u... "Neuroscientists like Earl K. Miller argue that the brain’s coordinated waves do the real work" #neuroscience @picowerinstitute.bsky.social @mitbcs.bsky.social

@matthiasmichel.bsky.social and I are pleased as punch to present the Fall schedule for the new MIT Consciousness Club. sites.google.com/view/mit-con... #neuroscience

By combining several cutting-edge imaging technologies, a new microscope system could enable unprecedentedly deep and precise visualization of metabolic and neuronal activity, potentially even in humans picower.mit.edu/news/mit-ima... #neuroscience #microscopy @mitbcs.bsky.social

Senior professors only wear lab coats for warmth.

Electroencephalogram Signatures of Propanidid-Mediated Sedation and Unconsciousness | Journal of Neurophysiology | American Physiological Society journals.physiology.org/doi/abs/10.1... #anesthesia #neuroscience

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience: Cell www.cell.com/cell/fulltex...

A new study by Mriganka Sur's lab shows benefits, but also limits, of environmental enrichment for Rett syndrome mice: onlinelibrary.wiley.com/doi/10.1002/... #rettsyndrome #neuroscience #neurology #research @mitbcs.bsky.social

🧠 New research finding: Astrocytes ensure neural information processing by maintaining ambient levels of the neurotransmitter chemical GABA picower.mit.edu/news/study-f... #neuroscience #brain @mitbcs.bsky.social

For undergrads who don't have enough opportunities at their home institutions to study #neuroscience, the MSRP-Bio program provides a summer opportunity to do research in our labs. Meet two current students: picower.mit.edu/news/when-li... @mitbcs.bsky.social @sciencemita.bsky.social

"In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity." MIT News: news.mit.edu/2025/in-down... Paper: journals.plos.org/plosone/arti...

A new comment in Nature Cell Biology reviews emerging evidence that oligodendrocytes, the cells that wrap the axons of neurons with myelin to improve electric signal transmission, may be critical players in Alzheimer's disease rdcu.be/eugVu

👀 Neurons add and shed synapses at a frenzied pace during development to integrate visual signals from the two eyes. picower.mit.edu/news/connect... #neuroscience #vision #research #development @mitbcs.bsky.social Research paper in Nature Communications: www.nature.com/articles/s41...

Autism advances Rooted in fundamental curiosity about how the brain works, Picower scientists continue to break new ground in understanding autism and devising treatment strategies picower.mit.edu/news/autism-... #neuroscience

Basic research yields applicable results. Learn how Picower scientists' fundamental curiosity about how the brain works has enabled them to break new ground in understanding #autism and related disorders and devise treatment strategies picower.mit.edu/news/autism-... #neuroscience

My first time writing for a high school alum mag--a profile of the illustrious Mark Bear of @mit.edu @picowerinstitute.bsky.social for St. Stephen's St. Agnes School. It was a pleasure to hear him reminisce about his early years & connect the dots of his career. sssasmagazine.org/wired-for-di...

🧩If you get a break today, take a spin with our science-themed puzzle: Cortex-Vortex. picower.mit.edu/cortex-vortex. We send a new one out with each free bi-monthly newsletter. Consider subscribing at picower.mit.edu/news/subscribe to also keep up with all our news and events. #neuroscience #brain

“We strive to present the hard science without making the science hard." Looking back and ahead as a leading #neuroscience textbook reaches 30 years and a fifth edition. picower.mit.edu/news/textboo... @mitbcs.bsky.social

🧠Decades of research on the genetic and molecular basis of neural plasticity has enabled Picower Institute Investigator Elly Nedivi to devise potential biomarkers for bipolar disorder. Read more: ilp.mit.edu/read/Nedivi #Neuroscience #bipolar @mitbcs.bsky.social

Spoiler alert: multitasking is bad What is scrolling doing to our brain? Emma Kennedy talks to world leading cognitive neuroscientist Dr. Earl K. Miller, the Picower Professor of Neuroscience at MIT, to find out what scrolling is doing to our brains. open.spotify.com/episode/46qo...

The immune system is a potent modulator of the brain and behavior. A deeper understanding of the brain-immune system relationship could unlock the therapeutic potential of immunomodulation for brain disorders, argues a new review co-authored by Gloria Choi. www.sciencedirect.com/science/arti...

#Alzheimers news: A campuswide collaboration at MIT will spark new research to develop assistive technology, enhance interventions, decipher brain biochemistry, advance big data analysis, and assess the public’s understanding of risk and protective factors. picower.mit.edu/news/aging-b...

To what extent, and how, do the brain and body's adrenaline systems communicate and collaborate? A new book chapter by members of the lab of Mriganka Sur maps it out. link.springer.com/chapter/10.1... #neuroscience #brain