Drs. Christian Gaebler, Samad Kor, Olaf Penack, and a team in Berlin found that after receiving a stem cell transplant, a patient discontinued antiretroviral therapy and sustained HIV remission for 6 years to date. 🖇️ https://go.nature.com/4j9OfnI 🎧 https://bit.ly/44Ay1OG

Congratulations to Drs. Jose Villadangos and Hamish McWilliam's (@hay-mish.bsky.social) labs on their @science.org paper! Their teams at the Doherty Institute showed that #macrophages are key for MR1 antigen presentation and MAIT cell immunity. 🗒️ https://bit.ly/49W1GW1 🎤 https://bit.ly/44Ay1OG

Happy Holidays from the Immunology Podcast team! ☃️ ❄️ We're taking a short break and will be back with a new episode on January 13th. Until then, we're dreaming of white blood cells and elf-ector T cells. 🎅 See you in 2026!

💉✨ Building a better flu vaccine — A joint study by the University of Michigan and the Institut Pasteur reveals that antibodies targeting the flu’s NA protein can help block not only infection but also transmission. Read more 👉 www.pasteur.fr/en/press-are...

Marjon Wouters, Isabelle Meyts @isabellemeyts.bsky.social and colleagues show that dominant negative ADA2 mutations cause ADA2 deficiency in heterozygous carriers 👉 rupress.org/jem/article/... 📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti... #InbornErrorsOfImmunity

This week: Maternal dust allergy and neonatal #RSV infection! Drs. Hamida Hammad and Bart Lambrecht's teams at @viblifesciences.bsky.social#RSVstudied how maternal factors influence RSV-associated allergic #asthma. Paper - https://bit.ly/3N7Mrj7 Discussion - https://bit.ly/44Ay1OG

An experimental vaccine against IgE protects against #anaphylaxis in humanized mice! Read the @science.org paper from a team at @pasteur.fr#anaphylaxis https://bit.ly/4s35z1L Listen to the discussion on our latest episode: https://bit.ly/44Ay1OG

Our immune system declines with age. Now the lab of @zhangf.bsky.social has found a way to overcome this decline by temporarily programming liver cells to improve T cells’ ability to fight infection.

Tune in to today's episode to learn about the role of the #microbiome in #Type1Diabetes! 🦠 Dr. Jayne Danska from @sickkidsvs.bsky.social#microbiome#Type1Diabetesoined us for a great conversation. Listen here: https://bit.ly/44Ay1OG

We can't wait to chat with Dr. Jayne Danska from @sickkidsvs.bsky.social next week! Her research focuses on #Type1Diabetes and the #microbiome. Stay tuned!

Shoutout to our listeners for proving you can love #Tcells, Taylor Swift, and #tuberculosis epidemiology all at once. Long live The Tortured Immunologists Department. 🤍 #SpotifyWrapped

The latest issue of #Science #Immunology is out now! This week: • evaluating large language models ( #LLMs ) / #AI as potential #systems #vaccinology tools • de novo #thymus #regeneration in the #axolotl! New content every week!!!

My latest 'pinch yourself' moment from the Lab. We previewed two really really exciting papers from the Eisenbarth and Pabst Labs for @cp-immunity.bsky.social Read our summary here> www.cell.com/immunity/ful... A big well done to Gaby Berman in my group and authors of both excellent manuscripts!

Present your #immunology research among the world's leading immunologists! Submit your abstracts today for #IMMUNOLOGY2026™. Upon submission, apply for an AAI Travel Award to assist with travel expenses to Boston, MA. ✈️ https://bit.ly/48cjOtl @aai.org#immunology

Recent work in @jci.org shows that subcutaneous white adipose tissue dysfunction triggers aging-like intestinal dysfunction in mouse models. Read the article: https://bit.ly/4rBatTB Listen to the discussion: https://bit.ly/4pJvw4u

A purr-fect place to record! 😻 @brendaraud.bsky.social is not the only one enjoying her soundproof setup. 😉

Feel better during the day than at night during #influenza? Find out the “Role of IL-10 signaling in the #circadian control of host response to influenza infection” www.mucosalimmunology.org/article/S193...

#Myeloid cells 🤝 #Lymphoid cells! Michelle von Locquenghien, Drs. Pascale Zwicky, Ken Xie, and Dr. Ido Amit's lab developed myeloid-targeted immunocytokines and NK/T cell enhancers that could potentially treat solid cancers. 📃@cp-cell.bsky.social#Myeloid#Lymphoid https://bit.ly/3Mkw3eM 🎧 - https://bit.ly/4pJvw4u

Sofía Ibáñez-Molero, Dr. Johanna Veldman, and a team in the @peeperlab.bsky.social at @nkinl.bsky.social isolated #Tcell clusters with high tumor-killing potential from patients with melanoma. Nature Portfolio paper - https://go.nature.com/4i7DjXv Episode - https://bit.ly/4pJvw4u

@aai.org invites you to submit abstracts of unpublished, original research for presentation at #IMMUNOLOGY2026™. This dynamic opportunity to showcase your research empowers you to connect, collaborate, advance your career, and access cutting-edge research. Submit & save today! https://bit.ly/48cjOtl

🫀New in #Circulation: Dr. Robert Schwab and a team in Dr. Avery Posey's lab engineered CAR Tregs that treat atherosclerotic plaques in mice. Article: https://bit.ly/3MdrZ01 Discussion: https://bit.ly/4pJvw4u #Atherosclerosis #HeartDisease

🔔 New episode alert! Dr. Ana Anderson from Harvard Medical School talks about her work on #ImmuneRegulation in cancer. ▶️ https://bit.ly/4pJvw4u

Coming soon! @aai.org's second round of regular abstract submissions opens Dec 2-16. Prepare your original, unpublished research for submission today. Travel awards will also be available for submissions made during this period. https://bit.ly/3Mkn5yd #IMMUNOLOGY2026

Join us next week for an episode with Dr. Ana Anderson from Harvard Medical School! Her research focuses on understanding the pathways and mechanisms that regulate the #AntiTumor immune response.

🥜 This week: #immunotherapy for #PeanutAllergy! A team at Stanford studied the mechanisms of oral immunotherapy-induced CD4+ T cell tolerance. 🖇️ - https://go.nature.com/4nBMSyP 🎧 - https://bit.ly/3JL4pXI

This week on the podcast: What causes long-term allergies? Dr. Zhoujie Ding and a team in Dr. Marcus Robinson's group at @monashbiol.bsky.social examined the lifespan of IgE antibody-secreting cells. @cp-immunity.bsky.social paper - https://bit.ly/48o4kT4 Episode - https://bit.ly/3X0SWpZ

New review out! 😊 20 years after it’s discovery, with @iannaconelab.bsky.social we decided to bring together what we currently know about this cytokine and how it shapes CD8 T cell responses. A small contribution to make sense of a field that is moving fast 🌈 @cp-trendsimmuno.bsky.social

There's a new episode out now! Dr. @georgearobinson.bsky.social from @ucl.ac.uk talks about his research on #lupus and #SexDifferences in autoimmunity. 📍 https://bit.ly/3JL4pXI

We have a new episode out! Dr. @camilahcoelho.bsky.social from Icahn School of Medicine talks about her lab’s work on mpox and other emerging viruses, her approach to #mentorship, and how her MBA education helps her in science. Listen now: bit.ly/43M7r4x

This week: A group led by Drs. Masayuki Amagai, Hayato Takahashi, and Miho Mukai converted conventional effector T cells into functional and stable Tregs. Read the paper: https://bit.ly/4qKYimH Catch the discussion on our latest episode: https://bit.ly/43M7r4x

📢 Laine Goudy, Dr. Luke Gilbert's lab, and their collaborators recently developed a new #epigenetic editing platform that safely reprograms multiple genes in human T cells. 📃 https://go.nature.com/3JQdKNL 🗨️ https://bit.ly/43M7r4x

Our next episode features Dr. Camila Coelho ( @camilahcoelho.bsky.social ) from Icahn School of Medicine at Mount Sinai! Tune in tomorrow to learn about her work on emerging viruses. 🦠

📢 New in @nature.com! Work led by Dr. Zihai Li at the Pelotonia Institute for Immuno-Oncology have shown that #ProteotoxicStress, induced by protein aggregation, is not merely a consequence, but a driver, of the exhausted T cell state. 📄: https://go.nature.com/47zVDog 🎧: https://bit.ly/3LlRCeo

New work from the lab of Dr. Wan-Lin Lo at @utah.edu demonstrates that age-dependent Zap70 expression regulates negative selection and thymic #Treg cell development. Study🗒️: https://go.nature.com/4o9oqWn Episode 🔊: https://bit.ly/3LlRCeo

Congrats to Drs. Mary Brunkow and Fred Ramsdell on receiving the #NobelPrize in Physiology or Medicine! 🏆 We discuss their early work identifying #FOXP3 as a master regulator of regulatory T cells. 🎧 https://bit.ly/3LlRCeo

In this week's episode, we review the seminal study from Dr. Sakaguchi that led to his recent #NobelPrize! It shows that a population of T cells expressing the IL-2 receptor α chain acts to maintain self-tolerance by suppressing other T cells. 📃: https://bit.ly/49f551F 🎧: https://bit.ly/3LlRCeo

🎤 Our next episode it out! We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection. 🎧 Listen now: https://bit.ly/4o2W8xa

Dr. Heather Parsons has been awarded the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research. Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood. 🎈 Congrats! https://bit.ly/3LlEpST

Online now: ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Bat sarbecovirus WIV1-CoV bears an adaptive mutation that alters spike dynamics and enhances ACE2 binding journals.plos.org/plospathogen...

Deletion of the X-escapee gene Kdm6a in microglia reverses the disease-associated microglial translatome and has protective effects in female mice www.science.org/doi/10.1126/...

Quantification of timelapse 3D tumor spheroid killing activity of NK cells using a live-cell imaging system @plosone.org journals.plos.org/plosone/arti...

What is the relationship between food allergies and #AtopicDermatitis? We cover a @cp-immunity.bsky.social#AtopicDermatitispaper from Boston Children's Hospital that explores how S. aureus skin colonization can lead to exaggerated #anaphylaxis. Check it out on our latest episode: https://bit.ly/4mXBKMr

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

🔔 New episode alert! Dr. Robin Orozco ( @robsorozco.bsky.social ) from the @universityofkansas.bsky.social joins us to chat about her work on allelic variation and immune responses. Stream it here or on any podcast app: https://bit.ly/46Jf7GI

Want to see immune cells in 3D? We’ve published a protocol for 5-plex 3D imaging of whole lymph nodes, revealing germinal centers at single-cell resolution. So many possibilities ahead! Congratulations Victoire Boulat! tinyurl.com/y9ekha8c #Microscopy #Immunology #SpatialBiology

Our next guest is Dr. Robin Orozco ( @robsorozco.bsky.social ) from @universityofkansas.bsky.social Her research focuses on the role of allelic variations in immunity.🧬 🔔 Tune in to the episode on Tuesday!

Happy #InternationalPodcastDay! 🥳 We're celebrating by counting down our top three episodes of the year below. 👇

Dr. Dayana Rivadeneira and a team in Dr. Greg Delgoffe's lab showed that dysfunctional T cells in cancer harbor damaged #telomeres, which arise from oxidative stress. 📄 - https://bit.ly/42MrvmK 🗨️ - https://bit.ly/4mybUyr

This week: Dr. Upasana Das Adhikari and a team in Dr. Douglas Kwon's lab at the Ragon Institute of Mass General Brigham, MIT, and Harvard studied how immunometabolic defects disrupt the intestinal barrier in people with #HIV. Paper: https://bit.ly/46wC5zp Discussion: https://bit.ly/4mybUyr