Researchers at KI, @uu.se and Northwestern University have identified a new way to protect the kidney’s blood vessels and reduce tissue damage in chronic #kidneydisease. The findings are published in @jclinical-invest.bsky.social. #Nephrology 🧪 news.ki.se/new-antibody...

Wallenberg Scholar Rickard Sandberg @ki.se aims to deepen our understanding of how the brain’s synapses develop by mapping gene activity in neurons. To achieve this, he is developing new methods of exploring the uncharted field of splicing #research @rickardsandberg.bsky.social tinyurl.com/mtpde34z

By 2021, 15% of young women in Stockholm identified as bisexual – a group facing greater mental health and social challenges than their heterosexual and homosexual peers. New KI study published in @amjpublichealth.bsky.social. #Sexuality #LGBTQ 🧪 ajph.aphapublications.org/doi/epdf/10....

The Iberian ribbed newt has the ability to heal its own heart after an injury. The secret might lie in a specific protein also found in humans. Elif Eroglu @ki.se studies salamanders to discover new ways of regenerating our heart cells after a #heartattack. #research #medicine tinyurl.com/mssmcmc2

A study from KI & @helsinki.fi published in @cp-cellrepmed.bsky.social shows that low interferon type I activity in ovarian cancer cells predicts poor response to platinum-based chemotherapy. Stimulating this pathway may improve outcomes for chemo-refractory #OvarianCancer 🧪 doi.org/10.1016/j.xc...

A study shows that cancer screening not only reduces the risk of dying from cancer – it also does not increase the risk of dying from other diseases. The results counter previous criticism of benefits and safety of screening. Published in ‪@jamainternalmed.com‬ 🧪 jamanetwork.com/journals/jam...

Frequent dried blood spot sampling in mice reveals transient proteomic changes that enable early prediction and prevention of #Type1Diabetes. The study is published in Diabetologia by researchers at KI, @kthuniversity.bsky.social and @scilifelab.se. #Proteomics #Diabetes 🧪 doi.org/10.1007/s001...

Final call: Applications close September 2! KI is recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. All positions: ki.se/en/about-ki/...

A new study in ‪@natbiomedeng.nature.com‬ introduces GenomePAM, a method for direct PAM characterization in mammalian cells. This technique leverages genomic repetitive sequences and does not require protein purification or synthetic oligos. #GenomeEditing #CRISPR 🧪 www.nature.com/articles/s41...

Wallenberg Scholar @gocastelobranco.bsky.social @ki.se is seeking to discover what happens in the brain during the progression of #multiplesclerosis (MS). His findings may lead to new ways of diagnosing and treating the disease earlier than is currently possible #research tinyurl.com/3kb22kkh

A new study in reveals three distinct genetic subtypes of follicular lymphoma, aiding in better diagnosis and personalized treatment. This could significantly improve patient outcomes. Published in ‪@cp-cellrepmed.bsky.social‬ 🧪 #Lymphoma #Genetics www.cell.com/cell-reports...

A new study published in Modern Pathology reveals that the growth pattern of breast cancer tumors after neoadjuvant treatment can indicate the risk of recurrence. This insight is crucial for assessing patient prognosis 🧪 #BreastCancer #Oncology www.modernpathology.org/article/S089...

Researchers have discovered a previously unknown molecule that may explain why people with type 2 diabetes often suffer from muscle weakness and muscle loss – a condition that has a major impact on quality of life. Research by @annakrook.bsky.social et al 🧪 news.ki.se/newly-discov...

A new study shows that artificial intelligence (AI) combined with portable digital microscopy improves the detection of intestinal worm infections, so-called soil-transmitted helminth (STH) in resource-limited settings. Published in Scientific Reports 🧪 news.ki.se/ai-microscop...

A new study has identified 18 potential drug targets for the treatment of multiple sclerosis, MS. The study may pave the way for new treatment strategies and drug development. Published in the journal ‪@pnas.org‬ 🧪 news.ki.se/new-potentia...

There is a perception that drugs such as ibuprofen and SSRI can trigger microscopic colitis (MC). However, a new study suggests that this is not the case – meaning that patients with MC do not need to stop taking these medications. Published in ‪@annalsofim.bsky.social‬ 🧪 news.ki.se/no-evidence-...

A study shows that both cognitive behavioral therapy (CBT) and an active online control treatment lead to significant improvements for people with stress-related disorders – but the effect varies depending on the diagnosis. Published in Psychotherapy and Psychosomatics 🧪 news.ki.se/internet-bas...

A new study in JAMA Psychiatry shows that while #ADHD medication still helps reduce the risk of self-harm, injury, traffic accidents and crime, its protective effects have diminished over time as ADHD medication use in Sweden has broadened to a wider group of patients 🧪 news.ki.se/adhd-medicat...

Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. 🔗 All positions: ki.se/en/about-ki/...

Long-term Western diet impairs islet blood vessel function and #insulin transport even after diet reversal and weight loss, according to a new study from researchers @ki.se #research supported by Knut and Alice Wallenberg Foundation #diabetes #medicine #obesity #metabolism tinyurl.com/yembuj9r

A KI study published in the British Journal of #Dermatology shows that patients with mycosis fungoides or Sézary syndrome face notably increased mortality, especially from #lymphoma and infections, highlighting the need for closer monitoring in severe cases 🧪 academic.oup.com/bjd/advance-...

Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence

A protein from the bacterium Helicobacter pylori has been shown to block the formation of harmful protein aggregates known as amyloids, that are linked to Alzheimer's, Parkinson's and type 2 diabetes, among other diseases. The study is published in Science Advances 🧪 news.ki.se/bacterial-pr...

A new study shows that women who are affected by cervical cancer are not only at risk of mental health and financial difficulties themselves – their children and partners also appear to be negatively affected. Published in Journal of the National Cancer Institute 🧪 news.ki.se/cervical-can...

Researchers have identified 3 types of nerve cells connected to the intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut. The study, published in @natneuro.nature.com, could lead to a better understanding of #IBS and #IBD 🧪 news.ki.se/mapping-the-...

An article published in @natmed.nature.com today highlights six key recommendations for implementing evidence-based #DigitalHealth interventions in routine clinical practice. This is crucial for managing noncommunicable diseases and improving patient outcomes. 🧪 www.nature.com/articles/s41...

Researchers have identified a gene variant that increases the risk of #LongCOVID. It is located close to the FOXP4 gene, which is known to affect lung function. The study, published in @natgenet.nature.com, was led by researchers at KI and @fimm-uh.bsky.social 🧪 #Genetics news.ki.se/a-gene-varia...

A study by @pelechanolab.bsky.social reveals how cells adapt to nutrient scarcity by altering their genetic instructions The discovery sheds light on cellular stress responses and opens up new medical treatments #research supported by Knut and Alice Wallenberg Foundation @ki.se tinyurl.com/nhbjcm48

A study by @pelechanolab.bsky.social reveals how cells adapt to nutrient scarcity by altering their genetic instructions. The discovery, published in @cp-molcell.bsky.social, sheds light on cellular stress responses and has potential therapeutic implications 🧪 #CellBiology news.ki.se/new-study-un...

Forskningen kräver fria internationella samarbeten - debattinlägg av Karolinska Institutets rektor Annika Östman Wernerson och prorektor Martin Bergö i @di.se di.se/debatt/forskningen-kraver-fria-internationella-samarbeten/

A study published in @cp-devcell.bsky.social points to new treatment strategies for the #childhoodcancer #neuroblastoma. Researchers have identified key transcription factor ‘switches’ that can be targeted to lock the cancer into a less aggressive state. #CancerResearch 🧪 doi.org/10.1016/j.de...

#Antibiotics administered together with the enzyme endolysin from bacteriophages protect against infection by resistant bacteria in all bodily organs in mice – including the brain, which antibiotics alone have difficulty reaching. Study published in Molecular Medicine 🧪 news.ki.se/researchers-...

Researchers have revealed how tetracycline antibiotics impair T cell function. The study raises important considerations for antibiotic therapy and developing new molecules to better distinguish pathogens and host cells. Published in Nature Communications. 🧪

Marcus Buggert and colleagues have identified biomarkers in the blood associated with symptoms of #LongCOVID, particularly severe respiratory problems. The discovery, published today in Nature Immunology, can pave the way for future diagnosis and treatment. 🧪 #PostCOVID news.ki.se/long-covid-b...

Researchers from @ucl.ac.uk and the University Alliance Stockholm Trio (@ki.se, KTH Royal Institute of Technology, @stockholm-uni.bsky.social) convened in London to explore collaborative research opportunities spanning #Climate, #Sustainability, and #BrainHealth. Read more ⬇️

KI researchers have engineered #extracellularvesicles to facilitate the delivery of therapeutic proteins and RNA, including gene editors, to cells. The method, presented in @natcomms.nature.com, shows promising results in animal studies. 🧪 #genetherapy #biotech news.ki.se/new-technolo...

A new study published in Intensive Care Medicine shows that intravascular cooling is more effective than surface cooling for patients who have suffered cardiac arrest outside of a hospital. The research could have significant implications for future treatments 🧪 link.springer.com/article/10.1...

Researchers have identified a new mechanism where circular RNA plays a crucial role in wound healing, which could lead to new therapies to improve wound healing and reduce scarring. The study was published in Advanced Science 🧪 news.ki.se/new-discover...

The incidence of pneumococcal haemolytic uremic syndrome has increased tenfold among Swedish children in recent years. This coincides with a change in the National Immunisation program from pneumococcal #vaccine PCV13 to PCV10 that protects against fewer strains 🧪 #Pediatrics doi.org/10.1001/jama...

A recent study found that phosphatidylethanol (PEth) levels can distinguish between different types of fatty liver disease and predict the risk of major liver outcomes. Published in @jhepatology.bsky.social by @liverepi.bsky.social et al 🧪#medsky www.sciencedirect.com/science/arti...

A newly published Cochrane review reveals significant gaps in the clinical rating scales used to assess pain in newborn babies, highlighting the urgent need for improved tools and global collaboration 🧪 www.cochranelibrary.com/cdsr/doi/10....

A new study from @ki.se shows how a small antibody fragment can block #fertilisation by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal #contraceptive one step closer to reality #research supported by Knut and Alice Wallenberg Foundation tinyurl.com/3hyvjaej

A new study shows how a small antibody fragment can block fertilisation by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal contraceptive one step closer to reality. Published in @pnas.org. Research by @lucajovine.bsky.social et al 🧪 news.ki.se/new-step-tak...

Researchers have identified guinea pig as a promising model for studying the development of human embryos. A study in Nature Cell Biology shows that guinea pig embryos share many characteristics with humans, which may open up new research opportunities in fertility 🧪 news.ki.se/guinea-pigs-...

A new study reveals that days with both high air pollution and extreme heat substantially raise the risk of death in Indian cities more than either factor alone. 🧪 Published in in Environment International. www.sciencedirect.com/science/arti...

In a study in @science.org, researchers @anderssonlab.bsky.social have used a new method to study how the nervous system and inner ear are formed in a mouse embryo. The discovery could provide important insights for future treatment of #hearingloss 🧪 #neuroscience news.ki.se/new-method-r...

A new study in Nature Medicine shows that researchers have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis among older adults living independently in the community 🧪 news.ki.se/blood-test-m...

The antimalarial dihydroartemisinin-piperaquine (DHA-PPQ) loses its prophylactic post-treatment protection upon repeated #malaria episode treatments, as it selects parasites carrying mutations in the plasmepsin 3 gene, finds a study published in @naturecomms.bsky.social 🧪 doi.org/10.1038/s414...

The Swedish National Patient Register, NPR, has good diagnostic accuracy for most diagnoses and very good for surgical procedures, according to a new review. The sensitivity is lower. Missingness is higher among private healthcare providers 🧪 #Epidemiology #MedicalResearch doi.org/10.1007/s106...

KI researchers have shown that material from nasal lavage provides a basis for assessing #COPD, chronic obstructive pulmonary disease. The study, published in the Journal of Allergy and Clinical Immunology, could lead to a simple diagnostic method 🧪 news.ki.se/protein-in-t...