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Online now: Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer’s disease by GM-CSF treatment

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Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer’s disease by GM-CSF treatment Sillau, Coughlan, Ahmed, and colleagues (University of Colorado Anschutz) found that cross-sectional neuronal death/damage (UCH-L1/NfL) plasma measures rise exponentially from age 2. Brain inflammation (plasma GFAP) rises exponentially from age 40, especially in females. A 3-week Alzheimer’s trial with cytokine GM-CSF improves cognition (MMSE) and neuropathology (plasma Aβ and Tau) and reduces neuronal death (plasma UCH-L1). http://dlvr.it/TQ129l