Please join us in welcoming our new Board members!👏 We look forward to their leadership, expertise, and continued contributions to advancing #diabetes research & care.🚀 Matthias Blüher, Miriam Cnop, Lena Eliasson & Tsvetalina Tankova #DiabetesResearch #DiabetesCare #Leadership

A recent, rather lesser noticed publication from the #DCCT #EDIC landmark study brought new insights on the long-term effects of #hypoglycaemia on #cognitivehealth. Hon Prof. Brian Frier reveals its relevance in our new #Gamechangers episode. 📺Watch here: easd-elearning.eu/episode/358/...

Behind every #diabetes breakthrough are dedicated researchers improving lives. Know someone who deserves recognition? @easdnews.bsky.social prize #nominations are now open! Help us shine a 🔦 on leaders shaping the future of diabetes #research. Stay tuned for prize highlights! 👉 www.easd.org/prizes/

Up front & free to read in our January issue #editorspicks: Shared and distinct metabolomics profiles associated with microvascular complications in the Diabetes Prevention Program Outcomes Study doi.org/10.1007/s001...

A study by China Medical University suggests that type 2 diabetes remission without surgery is possible via ADES, a device that mimics RYGB's electrical signals to restore beta cells and glucose control. #DiabetesResearch #Type2Diabetes link.springer.com/article/10.1...

Up front & free to read in our January issue #editorspicks: Persistent C‑peptide secretion is associated with favourable CGM metrics in adults with type 1 diabetes doi.org/10.1007/s001...

Macrophages within islets and the peritoneum interact to regulate beta cell function during peritonitis and type 2 diabetes #T2D #DiabetesResearch #BetaCells #Islets link.springer.com/article/10.1...

🌟Meet Dr. Rocky Strollo, #EFSD Future Leaders Mentorship Programme for Clinical Diabetologists awardee. His work maps oxidatively modified insulin fragments that trigger autoimmunity in #T1D. 🗣️“The EFSD #Mentorship was instrumental in my career.” 📖 doi.org/10.1007/s001... #DiabetesResearch #Funding

Up front & free to read in our January issue #editorspicks: Pharmacological therapies for type 2 diabetes: future approaches doi.org/10.1007/s001...

🎬Episode 7 of Best of #EASD2025 is live! Dr. Michael Leutner (Medical University of Vienna) shares his key highlights, focusing on the SOUL trial and new insights into #HeartFailure and peripheral artery disease in #T2D. 🎥Watch👉 youtu.be/EgoIFh2bT-M?... #Diabetes #DiabetesResearch

Up front & free to read in our January issue #editorspicks: Is the NOD mouse a good model for type 1 diabetes? doi.org/10.1007/s001...

Phosphodiesterase ENPP2 plays a key role in beta cell compensation during obesity via the LPA–LPA receptor 2-Akt/mTOR signalling pathway; modulating ENPP2 levels in beta cells may be a potential therapeutic strategy for managing T2D #Diabetes #Metabolism link.springer.com/article/10.1...

Meet our Editorial Board! metabologia.org/editorial-bo...

Our January cover illustrates detectives hunting down methylation marks to uncover ‘wanted’ loci. In this issue, Sinke et al report that DNA methylation at the SREBF1and ADIPOQ loci is implicated in adiponectin secretion and metabolic disease risk link.springer.com/article/10.1...

Human pancreatic #MesenchymalStromalCells express islet-protective ANXA1 and there are more MSCs around insulin-containing islets in #T1D. #MSC therapy may be most effective for individuals ≥13 years at diagnosis, where MSCs can better survive link.springer.com/article/10.1... 🔓

While islet amyloid harms β cells in T2D, research reveals amyloid protects against β cell autoimmunity and diabetes in NOD mice by disrupting MHCII antigen presentation in islet macrophages link.springer.com/article/10.1... 🔓

Diabetes has disproportionately impacted Indigenous Peoples for several years. This systematic review details global Indigenous adult type 2 #diabetes prevalence. Culturally grounded approaches are imperative to rectify epidemics of chronic diseases link.springer.com/article/10.1... 🔓

In a post hoc analysis of the #SURPASS-2 trial, #tirzepatide was superior to #semaglutide in attaining glycaemic management, weight loss and BP therapeutic targets in type 2 diabetes link.springer.com/article/10.1...

Combined intraduodenal administration of nutrients reduces postprandial glucose by slowing gastric emptying and stimulating gut hormones—a potential novel approach for management of type 2 diabetes #DiabetesResearch #T2D link.springer.com/article/10.1...

High intake of vitamin C and E might reduce the risk of islet autoimmunity and type 1 diabetes in children genetically at risk for type 1 diabetes. link.springer.com/article/10.1... 🔓 #vitaminA #vitaminB #vitaminC #vitaminD #vitaminE #Type1Diabetes #DIPPstudy

More fat, more #insulin: a study shows fasting hyperinsulinaemia rises continuously with #obesity, especially in men. Glucose, beta cell upregulation & liver overproduction play key roles. #type2diabetes link.springer.com/article/10.1... 🔓

α7nAChR activation reverses placental mitochondrial dysfunction in gestational diabetes, revealing a potential novel #therapy. By Lulu Ji, Lin Wang et al #GDM #Mitochondria #Placenta link.springer.com/article/10.1...

Meet our editorial team! metabologia.org/editorial-board/

Meet our Editorial Board! metabologia.org/editorial-bo...

Automated insulin injection adjustments generated by the McGill University #BayesianAlgorithm for adults with #T1D were non-inferior to those made by a group of expert physicians, supporting the algorithm’s use for clinical decision-making. #MDI #DiabetesTechnology link.springer.com/article/10.1...

Rethinking diabetes diagnosis: a meta-analysis shows that 1 h plasma glucose is superior to FPG, 2 h plasma glucose, #HbA1c or FPG plus HbA1c for detecting #Type2Diabetes earlier, potentially improving prevention and care #DiabetesResearch link.springer.com/article/10.1... 🔓

Study shows that neonatal #betacells sense gut microbiota-derived #bileacids via #FXR, limiting their development. Declining postnatal beta cell FXR expression allows normal neonatal beta cell growth and reduces #diabetes risk link.springer.com/article/10.1...

New findings from @CBMR.science show that insulin-resistance-linked hyperinsulinemia is associated with colorectal cancer risk, but not other diabetogenic processes. Largest study yet on this link – led by postdoc Xuan Zhou and @jmerino.bsky.social link.springer.com/article/10.1...

Lactate dehydrogenase A (#LDHA)-driven metabolic and epigenetic reprogramming in beta cell dedifferentiation during diabetes development, identifying LDHA inhibition as a promising therapeutic target. #DiabetesResearch #Pancreatic-β-cell #Dedifferentiaton link.springer.com/article/10.1...

Season's greetings to all from Diabetologia and @metabologiajnl.bsky.social and best wishes for the New Year

Please join us in expressing our sincere appreciation to our outgoing Board members for their dedication and service to EASD. 👏Ruth Loos 👏Patrick Schrauwen 👏Tina Vilsbøll 👏And Chantal Mathieu Wishing you all the very best - we’re sure our paths will cross again soon.

🎙️ Our final podcast of 2025: Half of teenagers with #diabetes now have #T2D and it's more aggressive than in adults. Dr. Tamara Hannon (Indiana University) and Prof. Martin Wabitsch (@uniulm.bsky.social) discuss the SURPASS PEDS breakthrough. 🎧 www.easd.org/media-centre.... See you in 2026!

🤝 We want to express our deepest gratitude for your continued support and engagement throughout the year! Wishing you a joyful holiday season and a successful New Year!🎄✨

ZnT8A detected in young children often progressed to multiple islet autoantibodies and were detected in multiple assay formats. ZnT8A detected by ELISA often remained single in older children and not detected in other assay formats #ENDIAstudy link.springer.com/article/10.1...

Our January issue is online now! link.springer.com/journal/125/... @easdnews.bsky.social @springernature.com @springermedicine.com @hinmul.bsky.social

In rural lean Indian women, pregnancy hyperglycaemia is only a window on a life-course of hyperglycaemia and not a de novo phenomenon, implying a major reconsideration of the timing of diagnosis & management of pregnancy hyperglycaemia (before pregnancy) is needed link.springer.com/article/10.1...

🎙️ What are the emotional burdens of living with diabetes hidden beneath the surface? Co-Chairs Jane Speight, Richard Holt & Michelle Law discuss the evidence-based clinical practice #guideline for assessing & managing #diabetes distress among adults with #T1D & #T2D. 🎧 www.easd.org/media-centre...

🎬Episode 6 of the Best of EASD 2025 series is now live! For the final episode of our Best of EASD 2025 series this year, we invited Romane Lartigue to share her personal highlights from her first EASD Annual Meeting. Watch here👉 youtu.be/w-QVVyeesro Stay tuned for more! #EASD2025 #Networking

⏰Just 3 weeks left to apply for the EASD Diabetes Technology School 2026! This is your chance to advance your skills in current and emerging diabetes technologies. 📅 Deadline: 5 Jan 2026 🔗 👉 www.easd.org/education/me... #DiabetesTechnology #DiabetesCare #Diabetes

🌟 Meet Prof. Jan Gojda, #EFSD Mentorship Programme awardee. His work uncovers key metabolic defects in pancreatic cancer cachexia, including muscle-specific insulin resistance and altered BCAA–lipid metabolism. 📖 pubmed.ncbi.nlm.nih.gov/38532464/ Generously supported by AstraZeneca #DiabetesResearch

❓What if most of our #T2D evidence doesn’t apply to those under 40? Prof. Melanie Davies explores #remission, #CGM, #stigma & more in the latest episode of '5 things we don't yet know'. 🎥Watch here: easd-elearning.eu/episode/355/...

🎙️A new chapter for EASD leadership. Outgoing President Chantal Mathieu & incoming President Francesco Giorgino reflect on achievements, continuity, & the future of diabetes research in an interview moderated by Stefano Del Prato. ▶️ Watch: youtu.be/xkU4uUgYzrE #diabetesresearch #leadership

In adults with #T1D, cardiovascular autonomic neuropathy was associated with exercise intolerance, characterised by impairments in various cardiopulmonary, metabolic and sympathoadrenal system responses to graded exercise. #DiabetesResearch #Exercise link.springer.com/article/10.1... 🔓

In HLA-predisposed children, family history of type 2 diabetes is associated with delayed progression from islet autoimmunity to diagnosis of type 1 diabetes #T1D #T2D #DiabetesResearch link.springer.com/article/10.1... 🔓

New research reveals MNX1 prevents SST expression and maintains beta cell identity by repressing PERCC1. This insight may help understand beta cell function and plasticity. #DiabetesResearch #BetaCells link.springer.com/article/10.1... 🔓

Up front & free to read in our Dec issue #editorspicks: Quantitative analysis of human adult pancreatic histology reveals separate fatty and fibrotic phenotypes in type 2 diabetes link.springer.com/article/10.1...

Powe et al identify that higher placental expression of GKN1 is associated with diminished beta cell function in pregnancy and GDM link.springer.com/article/10.1... @cepowemd.bsky.social

Meet our editorial board! metabologia.org/editorial-bo...

Ketones lower postprandial glucose excursions! A comprehensive study tested different ketone supplements—salts and esters at varying doses. Result: lower postprandial glucose responses in people with #T2D vs placebo link.springer.com/article/10.1...