#MedCase - A woman taking #adalimumab for ileocolic #CrohnsDisease presented with symptoms mimicking a flare. CT revealed extensive venous thrombosis, but respiratory symptoms developed and disseminated TB was diagnosed. 👉 buff.ly/eRNp0P9 #GastroSky #IDSky

#MedNews - Adding hormone therapy to postoperative #radiotherapy after radical prostatectomy does not significantly improve overall survival for most patients with #ProstateCancer. Full story 👉 buff.ly/84rsKVM #OncSky

#MedCase - The first report of late-onset axial #spondyloarthritis presenting with fever of unknown origin. Physicians need to be aware of rare manifestations of ax-SpA in the elderly population. 👉 buff.ly/i1TChoN #RheumSky #MedSky

#MedNews - Long-term adherence to the MIND diet may help slow structural brain aging. Full story 👉 buff.ly/bn0lrPA #NeuroSky

This position statement from the EASD and ADA Diabetes Technology Working Group emphasizes the need to support people with #diabetes to access and use the right tech according to personal needs, capabilities and preferences. 👉 buff.ly/ZODx8Jl #DiabetesMed

Review recent trials of #CARTcell therapy to treat common pediatric solid malignancies such as osteosarcoma, neuroblastoma, and retinoblastoma. What role can fourth-generation "armored” CAR T cells play? 👉 buff.ly/fLwRqRI #PediatricCancer #OncSky

Explore current imaging, serological, and immunological techniques for identifying hydatid cysts in cystic echinococcosis as well as the recent breakthroughs in recombinant antigen-based assays and nanobiosensors. 👉 buff.ly/tu6UOIM #IDMed

#MedNews - Study confirms that continuing #GLP1 or GLP-1/GIP agonists before elective upper #endoscopy raises residual gastric volume risk, supporting guidance to pause therapy prior to procedures. Full story 👉 buff.ly/ff1kRev #GISky

Cardiac and thrombotic problems are severe outcomes of #KawasakiDisease. The standard therapy is intravenous immunoglobulin plus aspirin but the ideal aspirin dose is still controversial. Find out more 👉 buff.ly/zojnCxj #RheumSky

Prof. Amer Zeidan and guest experts dive into the latest innovations in molecular testing, emerging therapies & targeted treatments in R/R acute myeloid leukemia #AML in this vodcast series. All episodes available now 👉 buff.ly/ro4GLtX #OncSky #HaemOnc

Targeted therapies could transform the treatment of pediatric #ALL. Take a deep dive into the mechanistic aspects of the agents, ongoing and recent clinical trial results and approvals, and the side effects of each modality. 👉 buff.ly/L21BPeS #OncSky #PediatricMed

#HeartFailure management has progressed significantly since the last European and American guidelines, with major advances across the HF spectrum. These are the findings likely to reshape contemporary practice. 👉 buff.ly/QIA0fEq #CardioSky

Around one in five cardiovascular deaths are attributable to environmental stressors. #AirPollution is perhaps the most prevalent, but how does it affect cardiovascular health? Dr. Anusha Seneviratne elaborates in our podcast. 👉 buff.ly/UChkXmD #CardioSky

#MedNews - Adding the anti-CD20 monoclonal antibody #obinutuzumab to standard therapy for systemic lupus erythematosus significantly reduces disease activity. Full story 👉 buff.ly/lbBXfea #RheumSky #SLE

#MedNews - Researchers have developed a #CRISPR assay that has shown good accuracy for diagnosing fungal #keratitis in patients with negative smear and culture results. Full story 👉 buff.ly/MDYy2ch #EyeSky

#MedCase - Consider testing thyroid function in patients receiving #pomalidomide prior to and then every 2–3 months during treatment. If drug-induced #hypothyroidism occurs, once the patient reaches a state of euthyroidism, rechallenge can be feasible. 👉 buff.ly/Oh4aqjM #OncSky

This landmark #MedCase documents the first human whole eye allotransplant following high-voltage electrical injury. Sustained globe viability & preserved outer retinal function at 1 year support its feasibility, despite absent visual perception. 👉 buff.ly/7IT0Rox #EyeSky #MedSky

Discover practical guidance for the diagnosis, management, and treatment of pediatric andrological disorders, including cryptorchidism, micropenis, hypospadias, and differences in sex development. 👉 buff.ly/HVKbgpO #EndoSky #PediatricMed

#MedNews - USP8 mutation status combined with tumor size helps predict recurrence risk after pituitary surgery in patients with #CushingDisease. Full story 👉 buff.ly/0q0Az0i #EndoSky #OncSky

The relationship between sex hormones and GI cancers in women is complex, with hormones being protective or predisposing. Understanding how hormonal, genetic, and environmental factors interact could improve #GICancer care for women. 👉 buff.ly/slaXTWA #GISky #OncSky

While there is some debate whether upfront combination therapy versus the traditional stepwise approach is more beneficial for LDL-C reduction, the suitability of either strategy is patient-dependent. Here is what to consider 👉 buff.ly/mTfjBqq #CardioSky

Underwater-ESD provides natural traction and enhanced visualization that aids removal of complex GI lesions. With ongoing refinements in the technique, U-ESD may become the standard in advanced therapeutic #endoscopy. 👉 buff.ly/3UasBlk #GISky

A significant proportion of people with #UlcerativeColitis don’t respond to the currently available treatments or lose response over time. Could repurposed medications offer a new way forward and how might they be used? 👉 buff.ly/gbtsVKo #GastroSky #IBD

#MedNews - The new AURIS score predicts candidemia risk in #ICU patients colonized with C. auris and outperforms the established Candida score. Full story 👉 buff.ly/4OJWEG6 #IDSky #Candidiasis

What's new in advanced therapeutics for #ParkinsonDisease? Explore the innovations in continuous infusion therapies, MR-guided focused ultrasound, deep brain stimulation, and emerging cell-based approaches that are expanding treatment options/ 👉 buff.ly/XBayPyK #NeuroSky

Thyroid eye disease: how do guidelines compare? Managing mild TED is highly consistent across European, Chinese, and American–European guidelines, but approaches diverge for moderate-to-severe disease and for specific patient populations. 👉 buff.ly/DBbyX0z #EyeSky

How does air pollution affect cardiovascular health? Listen to our conversation with Dr. Anusha Seneviratne to find out more about the known mechanisms, epidemiological evidence, and preventive measures. 👉 buff.ly/LwA4qpG #CardioSky #AirPollution @anushans.bsky.social

Discover the two conceptually distinct paradigms that could transform the neoadjuvant treatment of #cisplatin-ineligible patients with muscle-invasive #BladderCancer, and understand how they might be selected and sequenced. 👉 buff.ly/KzE5jri #OncSky

#MedNews - Patients with #SLE treated with #belimumab monotherapy have similar disease control, flare, and treatment response rates as those given the drug in combination with immunosuppressant therapy. Full story 👉 buff.ly/RgKk2Ri #RheumSky #Lupus

Get the latest insights into #WhippleDisease, from epidemiology and pathophysiology to clinical manifestations and treatment, in this review. Explore confounding factors in diagnosis and management, and current treatment limitations. 👉 buff.ly/FkYiR7r #IDSky #GastroSky

Emerging evidence shows smartphone-based portable slit-lamps – particularly when equipped with #AI – can deliver accurate, low-cost screening with automated detection and grading across key anterior segment disorders. Find out more 👉 buff.ly/JcbHwCv #EyeMed

Data suggests excessive oxygen use in brain-injured ICU patients contributes to secondary #BrainInjury. The optimal oxygenation approach remains uncertain, but clinicians must balance the competing risks of #hypoxemia and #hyperoxemia. 👉 buff.ly/bRaQKSy #NeuroSky #ICUMed

#MedCase - A reminder to consider #methotrexate as a potential cause of #gynecomastia, even with long-term low-dose therapy and in euhormonal states. Conservative measures such as dose reduction or folate supplementation may lead to symptom reversal. 👉 buff.ly/vzpk94B #RheumSky

#MedNews - Ten-year results of the LIR!C trial suggest that ileocecal resection offers a higher rate of long-term, therapy-free remission than #infliximab for patients with uncomplicated ileocecal #CrohnsDisease. Full story 👉 buff.ly/tWuNGOQ #GastroSky

#MedCase - Management of Lutembacher’s syndrome during pregnancy requires a coordinated, multidisciplinary approach to mitigate high risk complications. This case highlights the challenges of its management in a low-resource setting. 👉 buff.ly/CQjt6bU #CardioSky

#MedNews - Albumin replacement in #SepticShock does not improve 90-day survival compared with standard fluid resuscitation, the ARISS trial shows. Full story 👉 buff.ly/Vfrl5FY #IDMed #ICUMed

#MedNews - Early retinal drying in people with neovascular age-related macular degeneration receiving #faricimab treatment may signal improved disease control that allows subsequent injection intervals to be extended. Full story 👉 buff.ly/dJtmk3A #EyeSky #nAMD

#MedCase - #KrabbeDisease usually occurs in infancy, but adult-onset cases are increasingly described. KD should always be considered in very late-onset spastic paraplegia, as in this 66-year-old with concomitant cognitive decline. 👉 buff.ly/35C4T2i #NeuroSky

#MedNews - A single cardiac screening in just over 1 million young people in the general population has identified conditions associated with sudden cardiac death in 0.3% that led to risk-modifying treatment in 41.1% of cases. Full story 👉 buff.ly/iGKWCKU #CardioSky #SCD

#MedNews - Intravenous #tenecteplase thrombolysis within 24 hours of #stroke onset improves functional outcomes versus standard medical treatment in patients with basilar artery occlusion. Full story 👉 buff.ly/9jRKhBF #NeuroSky

#MedCase - This case of a #TesticularCancer patient with #CysticFibrosis and #LiverCirrhosis shows that monitoring of #etoposide concentrations can be beneficial in complex scenarios involving organ dysfunction and/or potential drug–drug interactions. 👉 buff.ly/RZnJ6yQ #OncSky

Biotics have the potential to improve #MetabolicSyndrome by reducing weight gain, insulin resistance, #dyslipidemia, inflammation, and improving glycemic control and gut barrier function. Find out more 👉 buff.ly/XzYD5ll #EndoSky #GutMicrobiome

#Burkholderia species present substantial diagnostic and therapeutic challenges due to their virulence and intrinsic antimicrobial resistance. This review synthesizes current knowledge on the clinically significant pathogens. 👉 buff.ly/pkTf3ui #IDMed #Melioidosis

#MedNews - An oral whole-cell vaccine against enterotoxigenic #EColi is immunogenic and well tolerated in infants, and should advance to a phase 3 trial. 👉 buff.ly/72hPj2b #IDMed #GastroSky

#MedNews - #SGLT2 inhibitors are linked to lower kidney, cardiovascular, and hepatic risks than #DPP4 inhibitors in patients with type 2 diabetes and liver cirrhosis. Full story 👉 buff.ly/OT68EkO #T2D

Given the association of #MASLD with cardiovascular, renal, and endocrine metabolic disorders, should cardiovascular-kidney-metabolic syndrome evolve to metabolic-associated liver-cardiovascular-kidney syndrome? 👉 buff.ly/BfSXQvW #EndoSky #MedSky

#VaricoseVeins and venous thromboembolism can occur in the context of chronic inflammation in inflammatory rheumatic diseases. Find out more about the key risk factors and prevention and rehabilitation strategies. 👉 buff.ly/Cc3fOVE #RheumSky

Explore the current knowledge of #BreastCancer brain metastases, from metastatic mechanisms to tumor microenvironment interactions, and learn how this understanding is driving diagnostic and therapeutic developments. 👉 buff.ly/DSlgvYL #OncSky

#Hyponatremia in HF reflects specific pathophysiological mechanisms that demand targeted intervention alongside standard decongestion strategies. This review outlines a phenotype-informed management framework to support effective care. 👉 buff.ly/23JR0Ze #CardioSky #HeartFailure

#MedCase - Slight pain related to eye movement and decreased VA indicated #papillitis. Rapid vision loss revealed an unusual initial finding of optic nerve involvement preceding retinal necrosis. But what was the cause? 👉 buff.ly/O7keMbc #EyeSky #IDSky