There are no words for how evil this is

Justice Jackson's dissent focuses on her belief that the government has failed to show any harm it suffers as a result of the policy being blocked, while the plaintiffs can show harm if it is in effect.

What this order makes clear is that plaintiffs can collect a mountain of animus, the district court can write extensively about the record, and the Supreme Court will just go “nuh uh.”

Reshaped, overhauled, refashioned-- in the Trump Administration it all means one thing: destroyed.

Jared Golden drops out of his CD-2 race citing the threat of political violence the same day Susan Collins glorifies and laughs at the jokes of a guy she once accused of having "incited" "terrorists" to "insurrection." 2025, people! #MEpolitics

My wife, who teaches at Chicago elementary schools, just shared this story on Facebook about ICE's and CPB's utter disregard for children at school.

This album opens so absolutely hard

Warning. ⚠️ If you are writing an NSF GRFP, new this year, you need official transcripts to apply. Beware. They will not review applications without official transcripts. ‼️

Not great for HMS security but these guys dressed in their jammies led me to feel like they were pranksters. Regardless - how did they get in through the roof - and how were they genius level to think an HMS building was abandoned???

One I missed because I didn't know it existed until after the book was finished – a B&W scan of the cover of Nature marking the 'coming of age' (ie 21st anniversary) of the double helix. I am trying to find a colour image of the original (most libraries stripped off the covers when binding...)

Brenner's copy of a New Yorker cartoon that was repeatedly moved around various noticeboards (note the pin holes)

(1/10) How do diverse leukemia mutations converge on the same molecular program? In #RibackLab first manuscript @cp-cell.bsky.social, collaboration with @goodell-lab.bsky.social shows that disparate mutations rewire shared protein networks to form nuclear condensates called C-bodies.

A functional map of CDK-drug interactions at single amino acid resolution https://www.biorxiv.org/content/10.1101/2025.11.02.685764v1

I will support any New York mayoral candidate who admits bodegas are just convenience stores and everywhere in the world has them

This World Series has been nothing but natural 1 attack rolls and natural 20 saving throws.

You guys baseballed so hard I got out of bed and turned on the game

WE ARE IN THE BASEBALL DIMENSION

Jon bois playoff hockey tweet but now for baseball

The helmet pop is the bat flip for rolling home from second

An unbelievable jam that you can’t imagine is real

So excited about this new work from our CardioVar consortium out this week in Science led by the amazing Daniel Tabet and @fritzroth.bsky.social. www.science.org/doi/10.1126/

arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review. This is due to being overwhelmed by a hundreds of AI generated papers a month. Yet another open submission process killed by LLMs.

The new Gates climate memo isn't a pivot; it's a continuation of "a consistent pattern of downplaying clean energy while promoting dubious and potentially dangerous technofixes in which he is often personally invested," @michaelemann.bsky.social argues in @thebulletin.org:

🚨 Chester Morris on TCM in NOV 🚨 Our boy is actually going to be on NOIR ALLEY next week!—THIS IS NOT A DRILL! BLIND SPOT (1947) airs on SAT NOV 08 at midnight ET SUN NOV 09 at 10:00 AM ET You can find this movie on YouTube or pirated etc but it's blurry shaky garbage —so be sure to catch this!

They literally ruin everything they touch

They dont give kids 100 grands or payday anymore we used to be a real country @triggerloop.bsky.social

Love this one so much

It‘s not officially out for another week (2 weeks in the US), but some copies have escaped into the wild! Happy reading!

She was so great and I didn’t realize until recently that she was blacklisted and this is another example (of course) where the wallet inspectors make so much money off the hand wringers who pointedly ignore where we usually see viewpoint discrimination

It really should be illegal for these to be opt out instead of opt in

They *lied*

JAM

Dr. Steven Henikoff receives the 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research. www.brandeis.edu/rosenstiel/r... (Personal note: I continue to be inspired and astonished by my postdoctoral mentor & current colleague)

Here it is. www.politico.com/news/2025/10...

I love AlphaFold—but please include PAE (Predicted Aligned Error) plots for every “interaction.” Pretty PDBs ≠ proof. If the PAE doesn’t show an interface, it ain’t one. Show the plots. Structural biology's reputation is on the line.

Not great guys

Two PROTAC questions: 1) Does anyone know of a PROTAC for GFP (which could be used to degrade any GFP-tagged protein)? 2) Does anyone have experience with any of the available PROTACs for Halo (like HaloPROTAC3)?

The supervisor said with no complainant he may continue to rock on.

South Side. S14th Street. Caller said a guy is outside on the sidewalk shredding guitar way too hard for a Monday afternoon.

Days before the 26th anniversary of its release, some thoughts on Michael Mann’s THE INSIDER. New at the Substack. open.substack.com/pub/peterave...

That's like 26 jettisons bsky.app/profile/juke...

Whenever people complain about the number of folks relying on food stamps, it is worth reminding them that SNAP is, by too large of a degree, a subsidy for corporations that refuse to pay a living wage and their political allies who reject public policy prescriptions to reduce income inequality.

@sickoscommittee.org they will ah e to rename the Rutger (more points than your opponent has yards) for this CU-Utah game

>>>>>

For the 8th Amendment, the shadow docket sleeps www.lawyersgunsmoneyblog.com/2025/10/for-...

Dripping Wet 7-Year-Old Gets On Hotel Elevator https://theonion.com/dripping-wet-7-year-old-gets-on-hotel-elevator-1819574036/

thanks, great work

It's interesting to call them SNAP "emergency funds." They are in fact legally required funds which Congress has provided and the president is choosing, once again, not to spend. It's a recapitulation of the torching of the power of the purse that is (or should be) the reason for this shutdown.