who decided to call it Secret Santa when Nondisclosure Claus was right there

I've been making small donations to Wikipedia for many years. Given the enormous service that it provides to all of us, it's in our collective interest to keep it smoothly running.

Listening to Bach and marveling, just marveling, at the fact that such music exists on this earth.

I now know how antigens feel... 😅

Most of us wouldn't be able to tell that this blot is fake! We're headed towards a topsy-turvy future. 😵‍💫

For 40+ years, the ASH Scholar Award has helped jumpstart careers in hematology—funding 678 awards, $82M in research, and $3B in follow-on funding. Learn more: https://bit.ly/4idJLvV #ASHAwards

Why did I never before realize that the Michelin that gives ⭐stars⭐ to restaurants for exquisite dining is the same puffy Michelin dude who sells tyres?!?

Step 1: Don't own any bitcoin.

It's so difficult to "score" applicants for our PhD and MD/PhD program this year - they are all so accomplished, eloquent, intelligent, and driven! My recommendation: Recruit them all! 😁

Hope this terrible law isn't passed by Congress...

No. No. Absolutely not. The ethics of primate research are complicated enough already. Please DO NOT bring back Homo erectus or some other extinct human ancestor!

Mutations in mitochondrial rRNA are recurrently observed in cancers! 😳🤯

Our latest paper has just been published in Cell! doi.org/10.1016/j.ce... We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.

👇👇 Mark your calendars! Fri, Dec 5, 3-7pm @ ASH. 🐔🐔

Important PSA! ASH Scientific Workshop website is experiencing a technical problem; YES, the Myeloid Workshop should be on the website and has an excellent speaker lineup already, stay tuned! @steidluli.bsky.social

I am a boring old lady and I already dropped off my mail in ballot weeks ago, but YOU CAN STILL VOTE TOMORROW (well, some of you). These elections REALLY MATTER, so please don't sit them out. Apathy is our enemy.

(1/10) How do diverse leukemia mutations converge on the same molecular program? In #RibackLab first manuscript @cp-cell.bsky.social, collaboration with @goodell-lab.bsky.social shows that disparate mutations rewire shared protein networks to form nuclear condensates called C-bodies.

What is the best fantasy film ever made? I nominate Pan's Labyrinth! One of the most extraordinary and devastating movies I've ever watched.

No spoilers, but was anyone else really frustrated with the ending of "A House of Dynamite"? The structure of the movie itself makes sense, but only if the ending is able to bring it together. The screenwriter and director entirely failed to achieve that goal.

Two PROTAC questions: 1) Does anyone know of a PROTAC for GFP (which could be used to degrade any GFP-tagged protein)? 2) Does anyone have experience with any of the available PROTACs for Halo (like HaloPROTAC3)?

I don't know if it's just me, but it seems like the deluge of fall pumpkin references in everything - recipes, restaurants, social media, television shows, decorations - is just increasing exponentially year over year! 🎃

The actor's Michael J. Fox Foundation is now 25 years old, and has raised over $2.5 billion for Parkinson's research. globalnews.ca/news/1149130...

Congratulations @oawlab.bsky.social! Richly deserved!

Congratulations @ksusztak.bsky.social and Gerd Blobel (not on Bluesky)!!!

New “discrete state” model of hematopoiesis published in Nature Immunology. rdcu.be/eL8oO We propose a hierarchical model of hematopoiesis where stable “discrete states” serve as key regulatory nodes.

This year the ASH Bridge Grant is funding 25 scientists with $3.75M, 5X more than last year, to keep hematology research moving forward. Congratulations to the recipients! https://bit.ly/3HJ51Ma #HemeSky #MedSKy #ASHAwards

Why is it that the one time I don't ask, "Can you see my screen?" it takes three slides of me explaining complex graphs before someone chimes in with, "Uh, I'm not seeing any shared slides..."

Is there a particular kind of PPT "aesthetic" that's most effective for scientific presentations? There's a slide format with a minimalist aesthetic of Cell Press journals (which I like) that I'm increasingly seeing at conferences - is there a website where people are downloading such a template?

Little-known fact: Checking the status of a submitted manuscript multiple times a day does not cause it to more rapidly move along the internal journal pipeline...

There comes a moment in your life when you realize that it's been forever since someone carded you at a bar or liquor store. That is a sad moment indeed ... 😢

It's a strange and vexing feeling to read and score grants for an upcoming NIH study section this month. I have no idea if the study section will even take place, but I do know that I owe each applicant a careful assessment...

How is it that Joan Steitz hasn't been awarded a Nobel?

227 autosomes! 😱💀 One can only be grateful that Thomas Hunt Morgan didn't use the Atlas blue butterfly as his model organism...

📽️ G&D Tapes 📽️ G&D Author, Aishwarya Pawar, tells us about their new study showing that PHF6 and PHIP function together to suppress stemness programs and leukemia progression. @aishwarya2510.bsky.social @paralkarlab.bsky.social Learn more here: ➡️ genesdev.cshlp.org/content/39/1...

This is beautiful! 🥲

RESEARCH PAPER: Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness By Pawar et al. and Vikram Paralkar Aishwarya Pawar Vikram Paralkar Learn more here:  ➡️ https://genesdev.cshlp.org/content/39/19-20/1219.abstract

What an incredible and impactful life!

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3] 📺 youtu.be/JmlY5omxQVc 📄 www.nature.com/articles/s41...

WAIT there's actually a bacterial culture medium called TERRIFIC BROTH?!? I thought it was just a joke that members in my lab were making... 😵‍💫

My cartoon for this week’s @newscientist.com

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

Not really an overstatement to say that the test of a free society is whether or not comedians can make fun of the country's leader on TV without repurcussions.

A random bit of history (for modern analogies). Lysenko set back genetics in USSR by ~50 years. Hundreds of geneticists imprisoned or died. Cybernetics was also named "reactionary pseudoscience", and about to undergo similar fate, but got lucky that this started close to the end of the Stalin era.

Excited to share our latest work on blood aging! To find out why the blood system changes as people age, we started at the source: hematopoietic stem cells (HSCs) #hemesky 🩸🧬 doi.org/10.1101/2025... 🧵 1/5

Actually, Frankenstein is a doctor success at the Venice film festival

Final version of Bingbing Duan’s main thesis work is out now now in Nature Communications @natureportfolio.nature.com www.nature.com/articles/s41... I’m so pleased with this study that we’ve been working on for so long #epistasis #transcription #geneexpression 1/

Delighted to present our work on Pol I in hematopoiesis at the @cshlnews.bsky.social meeting on Eukaryotic Transcription. Thanks to Mustafa Mir (my collaborator in the Penn Epigenetics Institute @pennepigenetics.bsky.social) for his lab's amazing single molecule imaging platform, and for this photo!

I am delighted to share that I have started my lab in the Dept. of Biochemistry @uofubiochem.bsky.social at the University of Utah @utah.edu. My laboratory will study key aspects of protein synthesis and translational control in healthy and diseased states. #RNAsky sinha.biochem.utah.edu