🦠 Can resistant bacteria protect their neighbours? A new paper reveals how β-lactamase activity, membrane permeability & antibiotic type shape antibiotic sheltering in microbial communities. Read it here: doi.org/10.1039/D5CB... #RSCChemicalBiology #AntibioticResistance #BetaLactamase

RSC Chemical Biology was proud to support the next generation of researchers at the 21st Annual Tri-Institutional Chemical Biology Symposium! Congratulations to all the winners!

Congratulations to Johannes Broichhagen (@broichhagenj.bsky.social) & team—winners of RSC Chemical Biology’s Outstanding Early Career Researcher Award for cleavable dyes to track GPCR trafficking & signalling! 📖 Read the paper here: doi.org/10.1039/D4CB...

🧬 Boosting mRNA stability through smart poly(A) tail design! New study explores chemical modifications that protect against degradation while preserving translation. Read here: doi.org/10.1039/D5CB... #RSCChemicalBiology #mRNA #RNAStability

RSC Chem. Biol. & Molecular Omics are sponsoring the EMBL’s The Epitranscriptome (28–30 Oct)! 🗓️ Today (16 Sept) is the last day to register for on-site attendance – be part of it in person! (Virtual registration open until 13 Oct.) 👉 www.embl.org/about/i... #Epitranscriptome

🧪 New in #RSCChemicalBiology: Breakthrough in phage display! By combining unnatural amino acids with CuAAC click chemistry, this study expands molecular diversity for next-gen ligand discovery. doi.org/10.1039/D5CB...#RSCChemicalBiology:#PhageDisplay #ChemicalBiology #ClickChemistry

🚨 New paper on enhancing NIR-PIT for cancer treatment! SiPc-1, a silicon phthalocyanine analogue, targets HTLV-1-infected cells with selective toxicity. Find out how this breakthrough could shape the future of ATL treatment 👉doi.org/10.1039/D5CB... #RSCChemicalBiology #NIRPIT #CancerResearch

🧬 Explore our new collection Biomolecular Technologies! Guest edited by Sheel Dodani & Ariel Furst, it showcases advances in engineered small molecules, nucleic acids & proteins for biocatalysis, biosensing & synthetic biology. 🔗 Read now: https://rsc.li/cbbmt25

🧠 New bioconjugation trick for tracking serotonylation — no tryptophan needed! 📝 New work from Qingfei Zheng et al. 📄 "Regioselective rapid ene-type reaction (RRER) enables bioconjugation of histone serotonylation" 🔗 Read the full paper:

🚨 Breakthrough in targeting cancer-related protein aggregation: "Random peptide mixtures of tryptophan and lysine suppress the aggregation of a cancer-related mutant of the Axin protein" by Assaf Friedler et al. 🔗 Read the full article:

Don’t forget! The Tri-Institutional Chem Bio Symposium is Aug 28 🧬 Proudly sponsored by RSC ChemBio + ‪@rscmedchem.rsc.org‬! 🗓️ Reg closes Aug 20 🧪 Posters welcome from all attendees 📍 At ‪@mskcancercenter.bsky.social‬ Be there! #ChemBio #MedChem #ScienceSymposium #RSCJournals

From Rheinheimera japonica 🦠 — a marine LPS with unusual structure 🌊 and weak TLR4 activation, but able to antagonize E. coli LPS. Published in RSC Chemical Biology. 🔗 Read the full article: doi.org/10.1039/D5CB... #MarineBiology #Immunology #RSCChemicalBiology

📣 Present your research at EMBL’s The Epitranscriptome (28–30 Oct)! 🧬 RSC Chem. Biol. & Molecular Omics are sponsoring poster prizes. 🗓️ Abstract deadline: 5 August – submit now! 👉 www.embl.org/about/i... #Epitranscriptome #RSCChemBio #MolOmics #ScienceSky

New in RSC Chemical Biology: Synthetic mucins 🧬 — made with native-like glycans to probe how glycosylation affects protein structure and degradation. A new tool for glycobiology and biomedical research. 🔗 Read full article: doi.org/10.1039/D5CB... #Glycobiology #RSCChemicalBiology

New in RSC Chemical Biology: EBI ⚡ — promising for food safety, but how can AI 🤖, MAP, and natural antimicrobials 🌱 help scale it up? We explore solutions in our latest review. 🔗 Read full article: doi.org/10.1039/D5CB... #FoodSafety #EmergingTech #RSCChemicalBiology

Excited to sponsor the 21st Tri-Institutional Chemical Biology Symposium on Aug 28 at ‪@mskcancercenter.bsky.social‬ 🎉 RSC Chemical Biology + ‪@rscmedchem.rsc.org‬ are proud to support this event 👩‍🔬👨‍🔬 Poster subs open! Reg by Aug 20 🔬🧪 #ChemBio #MedChem #TPCB #RSCJournals

New in RSC Chemical Biology: SpyBLI — a fast, low-cost way to measure binding kinetics straight from crude samples. No purification, no cloning, data in under 24h. A game-changer for binder engineering! DOI doi.org/10.1039/D5CB... #ProteinEngineering #SpyBLI

We're pleased to announce that Cecilie Mia Jørgensen (@ceciliejoergensen.bsky.social) has won the RSC Chem. Biol. and Org. Biomol. Chem. (@orgbiomolchem.rsc.org) poster award at the 2025 Peptide and Protein Science Group Early Stage Researcher Meeting! Please join us in congratulating Cecilie.

🎉 Honouring the Outstanding Reviewers of 2024 for RSC Chemical Biology! A huge thanks to these scientists for their time, care, and dedication to keeping science strong. 👉 Read the editorial here: doi.org/10.1039/D5CB... #PeerReview #ChemicalBiology #OpenScience

ZBTB20’s zinc fingers pack a punch 🧬Seung Jae Lee et al., show how it targets AFP & FOXO1 to regulate tumor pathways with the first biochemical proof of its DNA binding. Read the full paper here: doi.org/10.1039/D5CB... #ZBTB20 #ChemicalBiology #CancerResearch #RSCChemBio

New #RSCChemBio study pinpoints how two residues (F103 + Q120) power the parainfluenza fusion peptide’s membrane activity. One’s for fusion, the other’s for the teamwork. #OpenAccess #advancearticle #Virology #Peptides #MembraneBiology doi.org/10.1039/D5CB...

Exciting news! Our Editorial Board member, Ali Tavassoli, has won the 2025 Interdisciplinary Prize! 🎉 Ali is being recognised for pioneering creating new approaches to target "undruggable" protein–protein interactions. Check out Ali's work here 👉 doi.org/10.1039/C8SC...

🎉 Today we reveal the 2025 RSC Prize winners! 🎉 Celebrating excellence across research, diversity, tech roles, apprentices and partnerships. Join us in congratulating the remarkable individuals and teams advancing chemistry for society. buff.ly/K2un4O1 #Chemistry #ChemSky

Tougher peptides, smarter targets 🔒🧬 Cyclic β-amino acid–based helical peptide library leads to stable, cell-permeable SARS-CoV-2 Mpro inhibitors! New #RSCChemBio #advancearticle shows off RaPID selection power 💥 doi.org/10.1039/D5CB...

#ChemBioParis2025 🚨 Early Bird Registration & Abstract Submission CLOSES TOMORROW! Register & send you abstract today! 📍 Sorbonne Université, Paris 📆 6-9 October, 2025 Register below 👇 🔗 lnkd.in/dpfzrSpX#ChemBioParis2025 #ICBS2025 #ECBS2025 #ChemBio

Zoom in on CXM 🔬 New #RSCChemBio study reveals how chuangxinmycin hits bacterial TrpRS enzymes—but not human ones. 10 crystal structures + MD sims = a blueprint for selective antibiotic design. #RSCchembio #StructuralBiology #Antibiotics #TrpRS #AMR doi.org/10.1039/D5CB...

The Early Stage Researcher Meeting 2025 at @unibirmingham.bsky.social is on July 10! The @rsc-ppsg.bsky.social event includes oral presentations by PhD students, postdoc researchers, and a poster award session. 🗓️ Register by June 20 👉 https://bit.ly/3TsMCFK #PPSG2025

✨ Sugar, lit. ✨ GluRho is a new glucose mimic that uses GLUTs 1–4 to light up sugar transport in live cells (and flies!). Great tool for tracking uptake with no metabolic interference. New in #RSCChemBio #OpenAccess #advancearticle doi.org/10.1039/D4CB...

RSC Chemical Biology and Organic & Biomolecular Chemistry (@orgbiomolchem.rsc.org) are proud to support the 17th International Symposium on Biocatalysis and Biotransformations in Basel, 29 June-3 July 2025. Don't miss your opportunity to participate: www.biotrans2025.com

🚨 It’s deadline day! Submit your abstract for a talk or poster at #PPSG2025 by the end of today (5 June)! We’d love to hear your work in protein/peptide science 🧬 🔗 www.rsc.org/events/d...#PPSG2025

🚨RSC Chemical Biology is online and #openaccess! Cover: John Pezacki et al., "Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques" 👉Read: doi.org/10.1039/D4CB... 👉Meet our Emerging Investigators 2024: doi.org/10.1039/D5CB...

Looking forward to the start of PTF25 tomorrow in Basel! More info: https://ptf25.scg.ch #PTF25 #chemistry #orgchem #academicbsky #openscience

Hotter enzymes, faster: 🔥 This #RSCChemBio study shows EVmutation outperforms FoldX in predicting cellulase variants with up to 4.4× more activity & longer life at 75 °C! #OpenAccess #advancearticle #ProteinEngineering #Enzymes #Biotech DOI doi.org/10.1039/D5CB...#RSCChemBio

REGISTRATION CLOSING SOON ⏳ Poster submission and registration for #BGFP25 closes on 02 June!! Don’t miss out on the opportunity to join Karlene Cimprich, Agnel Sfeir, Dipanjan Chowdhury and their fantastic speaker line up in sunny Portugal this July! Register here: bit.ly/3FmrcXo

Lighting up cancer’s dark side 💡 A new NTR-sensitive bioluminescent probe enables real-time imaging of breast cancer bone metastasis — tracking tumor hypoxia with precision. No external ATP needed. Just glow. 👉 doi.org/10.1039/D4CB...

🚨 LAST CHANCE TO REGISTER FOR #Nucleic25 Don’t miss your chance to join our chairs David Lilley and Wei Yang at an engaging and impactful meeting. Click here to register now: bit.ly/4dq18Ho

SUPER EARLY BIRD DEADLINE APPROACHING! 🚨 Don't miss your chance to join John Tainer and Xiaodong Zhang at #DRRSC26 This meeting is a sellout! Make sure to secure your spot before 26th May 2025 for the best price available 🎉 Click here to register: bit.ly/3HmMLHS

🚨 Due to high demand, registration for #DDRCT25 has been re-opened until 29 May! ⏳ Limited spots remain and they’re going fast. 💰 Grants available for ECR's. See the website for further details & to secure your spot 👉https://bit.ly/3H8GgbH

👀 A gentle nudge! ⏳ Abstracts for @rsc-ppsg.bsky.social are due 5 June 📝 Registration closes 20 June Don’t miss out on this friendly and focused event for ECRs in protein/peptide science. 🔗 www.rsc.org/events/d... #PPSG2025

IP6 is cool, but IT6 is cooler 😎 A thiophosphate swap makes inositol hexakisphosphate more stable, more soluble, and stickier to bacterial virulence factors. Great news for structural bio & drug design! 📖 doi.org/10.1039/D4CB...

Early career researchers — don’t miss your chance! 🧬 Join us in Birmingham for #PPSG2025, the @rsc-ppsg.bsky.social Early Stage Researcher Meeting. 🗓️ Registration closes 20 June 📍 July 10, 2025 🔗 www.rsc.org/events/d...#PPSG2025,

The 2025 RSC CBBG (@rsc-cbbg.bsky.social) Postgraduate Symposium takes place on 13 June! RSC Chemical Biology and @orgbiomolchem.rsc.org are proud to support this meeting for early career chemical biologists. If you'd like to attend, be sure to register by 23 May. www.rsc.org/events/detai...

Splice modulators, meet your match. 🔦 Using photoaffinity labeling + Chem-CLIP, researchers mapped small molecule–RNA binding across the transcriptome and found... telomerase?! Wild. Read the study: doi.org/10.1039/D4CB...

Kinases: not just for animals anymore. 🧪 A p38 signaling pathway in choanoflagellates shows stress response roots run deep. Ancient cell drama, now with kinase inhibitors! Read this cool crossover: doi.org/10.1039/D4CB...

RSC Chem. Biol and @orgbiomolchem.rsc.org are proud to support the @rsc-cbbg.bsky.social Postgraduate Symposium taking place 13 June at the University of Aberdeen. Oral abstracts are due by this Friday, 9 May, and posters by 16 May. Find out more: www.rsc.org/events/detai...

Calling all early career researchers! Got great peptide or protein science to share? Submit your abstract for a talk or poster at @rsc-ppsg.bsky.social, happening Jul 10, 2025 at University of Birmingham 🧬 Deadline: 5 June ✨ Info: www.rsc.org/events/d... #PPSG2025

What’s your mRNA up to during mitosis? 🧬 New study uses enzyme-powered proximity labeling to track DLGAP5 mRNA heading to the centrosome like it’s got a job to do. Centrosomal road trip, anyone? 🧪📍 Read it here: doi.org/10.1039/D4CB...

We’re pleased to announce our latest Emerging Investigators article collection, highlighting work from outstanding early career researchers selected from the chemical biology community. Discover this exciting work, all #openaccess and free to read, at rsc.li/CBEMI24.

In this #advancearticle Kazunori Matsuura et al., have developed an innovative peptide-based approach to construct complex microtubule superstructures, including doublets and bundles, using Tau-derived peptides! 🧬 Read the full paper here: pubs.rsc.org/en/content/a...

Unwind from the week and read this paper on epigenetic sequencing by Sabine Schneider & Thomas Carell et al from the Ludwig-Maximilians-Universität München 🧬. Read the paper below 🌟 pubs.rsc.org/en/content/a...