📽️ G&D Tapes 📽️ G&D Author, Aishwarya Pawar, tells us about their new study showing that PHF6 and PHIP function together to suppress stemness programs and leukemia progression. @aishwarya2510.bsky.social @paralkarlab.bsky.social Learn more here: ➡️ genesdev.cshlp.org/content/39/1...

OUTLOOK: A new link in the leukemia genetic puzzle By Xiaodi Wu and Ross Levine Learn more here: ➡️ https://genesdev.cshlp.org/content/39/19-20/1129.full

I so excited to see my thesis work in @paralkarlab.bsky.social being published in this issue of @genesdev.bsky.social along with an outlook article about our work in the same issue by @rosslevinemd.bsky.social and @xwu.bsky.social. It’s been a long journey but so worth it!

RESEARCH PAPER: Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness By Pawar et al. and Vikram Paralkar Aishwarya Pawar Vikram Paralkar Learn more here:  ➡️ https://genesdev.cshlp.org/content/39/19-20/1219.abstract

And many thanks now to @xwu.bsky.social and @rosslevinemd.bsky.social for this thoughtful commentary on our work! This was genuinely unexpected icing on the cake!

We at @paralkarlab.bsky.social are very excited to bring this to you! Take a look and catch us at #ASH24 this weekend in San Diego.

📣 New preprint from our group! 📣 We report a novel mechanistic connection between PHF6 and PHIP, two disparate leukemia-mutated proteins. Fantastic PhD work of Aishwarya Pawar (@aishwarya2510.bsky.social) in the @cambupenn.bsky.social UPenn Cancer Biology graduate program. Highlights below: (1/n)