Umut Gerlevik
@ugerl.bsky.social
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Circadian | Chromatin | RNA @Furger Lab, Department of Biochemistry, University of Oxford
🧬 New preprint! SNU-Seq maps nascent transcription at single-nucleotide resolution using 4sU labeling. Together with sf4sU-Seq, it shows how epigenetically primed chromatin rapidly activates transcription after IFN-γ. 📄
doi.org/10.1101/2021...
#SNUSeq
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Single Nucleotide Resolution 4sU Sequencing (SNU-Seq) reveals the transcriptional responsiveness of an epigenetically primed human genome
Genomes are pervasively transcribed, leading to stable and unstable transcripts that influence 3-dimensional genome organisation and gene regulation. High sensitivity and nucleotide resolution are req...
https://doi.org/10.1101/2021.07.14.452379
22 days ago
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