🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉 Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨ #PhD #3DGenome

This work is now officially published @natsmb.nature.com with some fun new analyses included in the revised version. Congratulations to all the authors! @connyyu.bsky.social @rappsilber.bsky.social @lrsinn.bsky.social @fjoreilly.bsky.social www.nature.com/articles/s41...

www.embl.org/about/info/c... courses and conferences A single session on the nuclear pore and everyone can happily depart?

New paper with @statsepi.bsky.social and @deevybee.bsky.social in which we show there's really no evidence for a link between the gut microbiome and autism www.cell.com/neuron/fullt...

Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp

Fantastic breakthrough for Type 1 Diabetes by @helmholtzmunich.bsky.social

We have a new lab photo. Busy times in the Delas Lab! Last month Maria and Shaun joined us to start their PhDs. Learn more about our research and our team: delaslab.com We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.

📢 Don't miss @groth-anja.bsky.social from the Danish Cancer Institute, who will present her research at the #Embryo2026 🧬 "How cells copy their epigenome" Register until Oct 31! 👇 www.molgen.mpg.de/embryo2026 Supported by the Weizmann Institute of Science

Chromatin fatigue: DNA repair alters the chromatin environment and introduces heritable variation in gene expression in a larger region around the lesion! Amazing achievement by @sbantele.bsky.social and Jiri Lukas published in @science.org 🙌 Happy we could contribute. See 👇

FastGA -> ALNview; step into the centromeric matrix! github.com/thegenemyers Probably the best dot plot software on the planet...

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

I’m fascinated to try this. It’s such a relief to see the journey we are on that started with the launch of BioRxiv and that could liberate us from the most depressing aspect of science - “getting published”.

📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...

Nice! Check it out!! 🙏

Considering the LMB for your PhD? We’ve got over 25 projects available, covering a wide array of topics. Check them out here: www2.mrc-lmb.cam.ac.uk/students/int... Apply by 2nd DEC for Autumn 2026 admission.

Lots of exciting PhD projects on offer at the LMB, including in our group 😊

Very proud!

Neanderthal DNA enhances our understanding of face development This Research Highlight showcases the work from Hannah Long @hannahlong.bsky.social, Kirsty Uttley @kirstyuttley.bsky.social, Hannah Jüllig @hannahjuellig.bsky.social and colleagues: journals.biologists.com/dev/article/...

🧬 Interested in dissecting dose-dependent transcriptional regulation through epigenome editing and synthetic biology for your PhD? Apply by 07.01.2026 to join the lab of @eddaschulz.bsky.social @molgen.mpg.de & #IMPRS-BAC #gradschool. 👉 www.molgen.mpg.de/5099133/schu...

this looks very interesting with numerous implications for nuclear biology and gene expression. Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions: Cell www.cell.com/cell/fulltex...

Exactly. We can deposit papers on preprint servers and we can even request an independent peer review (review commons) process all for free. While we keep needing the journal labels not much will change.

Oh, and this also means it would be possible for multiple journals in parallel to highlight your paper. You won't be restricted to just one (similarly to how the BBC, NYT and Scientific American can all highlighted your journal-published paper today).

When people celebrate the individual genius of folks in science, they should also mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)

You’ll be proud that your reviewed preprint was highlighted by Nature, just like you’re proud when your paper is highlighted by the New York Times. You'll add that to your C.V. You'll still read them because they'll have good content (2/2).

The idea is to decouple the journals from the review step. They’ll still exist, but they’ll need to add other value. They’ll highlight, curate, add new perspectives. If they do a good job they can still be prestigious (like Scientific American or Wired) (1.2) 👇

So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression. @ceesdekker.bsky.social @uoe-igc.bsky.social

Fabulous talk by Haruhiko Koseki today @oxfordbiochemistry.bsky.social followed by a fun dinner with Neil Brockdorff and @aleksszczurek.bsky.social ! Thanks for visiting Haruhiko!

We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...). We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇

Personal good news alert: I’ve been promoted to associate professor and it’s time to update the ol’ bio! Launching my lab at UCSF has been a privilege + I’m so grateful to my team and community here. More exciting science ahead! 🚀

Very excited and honored that our project CenAGE with @manellab.bsky.social and Elsa Logarinho was granted! Looking forward to discover how centromere instability affects the immune cells contributing to systemic ageing. More Info here: curie.fr/actualite/no... Open positions soon, stay tuned!

New paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at @imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys

Great! We were musing at lab mtg how this would be ideal for bioRxiv and here you go. Smart partnership.

Please read the thoughtful Blog that @richardsever.bsky.social and the @openrxiv.bsky.social team wrote on integrating pre-prints with AI review openrxiv.org/enabling-rev...

Amazing. It’s funny I was just talking about this possibility today with colleagues.

Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n openrxiv.org/enabling-rev...

I am thrilled with the news that our ERC Synergy proposal GeneMotors was granted!! This prestigious grant allows Leonid Mirny (MIT), Wendy Bickmore (Edinburgh), Benjamin Rowland (NKI) and me to study the DNA-looping SMC motors proteins that control our chromosomes in the next 6 years

Congratulations Matt and team! So well deserved!

The Wellcome Trust has awarded a prestigious Discovery Award to Professor Matt Higgins to support his research on “Molecular mechanisms of erythrocyte invasion in malaria”. 👏👏👏 Read the full story: ⬇️

Awesome stuff James and team! Thanks for giving @edimitrova.bsky.social and I the opportunity to contribute.

Our latest paper has just been published in Cell! doi.org/10.1016/j.ce... We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.

Exciting work from Hangpeng and James! Very nice explainer. Happy to have been able to contribute.

Not from Tron or a psychedelic wallpaper. This exquisite pic reveals chromatin at base-pair resolution, captured by #ListerFellow James Davies and collaborators🤩 "For the first time, we can see how the genome's control switches are physically arranged inside cells." @jojdavies.bsky.social

When you decline an invitation to review a manuscript but suggest colleagues you’d like to keep occupied as “suitable alternative reviewers”

🥁This Wednesday , in #FragileNucleosome seminar, we are excited to host @hannahlong.bsky.social and @jeffvierstra.bsky.social to tell us about amazing work they are doing! 🗓️Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...

@ckadoch.bsky.social and I are excited to welcome you to Geneva for the 2026 Keystone Symposium on Epigenetics and Gene Regulation in Health and Disease — short talk and poster slots are still open. Don’t miss the deadlines. Video: youtu.be/sLfyuQuH8F0

This is Frank Lyko’s product!

Vincent (Colot) was given one as a gift for his retirement party… I hope he will not flower too early…

‘Epigenetic serum’ makes you wonder !

However long I live here I will never get used to how utterly beautiful the views from Princes St are. This was last night 😍

My sister has come up some cracking #vintage #knitwear designs recently as part of her sustainable knitwear initiative. This is my fav- love the mirrors. Check out on Etsy: www.etsy.com/uk/shop/Grac...