Benoit Bruneau
@benoitbruneau.bsky.social
📤 5764
📥 2060
📝 2355
Cardiac developmental biologist. Oakland and San Francisco. Hi friends! 🇨🇦
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Benoit Bruneau
Craig Kaplan
about 14 hours ago
Stark, dark, but that’s it. I would say support your friends and colleagues and preserve what we can
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Yeah on my way to work one that had just dropped off a rider quickly backed into traffic and just stayed there. 🙄
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1 day ago
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they're talking about goalie aggression, but nothing tops Ron Hextall
1 day ago
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what the heck is going on with the goalies in this game? Five goals in 15 minutes?
1 day ago
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Benoit Bruneau
Brooke Jarvis
1 day ago
Today in neighborhood bumper stickers
#bugsky
#insectthursday
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Benoit Bruneau
Max Kozlov
1 day ago
NEW: A serious staffing shortage — of the Trump admin's own making — is delaying the agency's ability to send billions to universities around the country, leaving labs reeling in the meantime. “I thought we were at rock bottom”, a senior NIH official said. “We are below rock bottom now.”
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NIH staffing shortage could slash number of new grants issued this year
Some units at the US funding giant are so understaffed, they are focusing on mandated grant renewals rather than new awards.
https://www.nature.com/articles/d41586-026-01537-1
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Benoit Bruneau
Genetics Society of America
19 days ago
New in
#GENETICS
from
@hainerlab.bsky.social
: The nucleosome remodelers esBAF and INO80 selectively influence subcompartment identity and enhancer–promoter communication at key regulatory loci during higher-order chromatin organization in mice. 🔗
buff.ly/0eU5xg0
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To commemorate the lab’s 25 th, lab gifted me a lovely photo montage (man I look young in the older ones) and an awesome personalized guitar strap!
2 days ago
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Benoit Bruneau
Wendy Miller
3 days ago
Burrowing owls turn food delivery into a work of art. 🪶
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Molly Knight
3 days ago
Jason Collins died of glioblastoma today. He was a wonderful person. This is awful
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This thread firstly upends how we think things work, and also illustrates the power of modeling paired with experimentation
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3 days ago
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Benoit Bruneau
Elphege Nora Lab at UCSF
3 days ago
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬
Our new study
spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By
@timothyfoldes.bsky.social
💻&
@karissalhansen.bsky.social
🧪 🧵👇
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Benoit Bruneau
WeRateDogs
5 days ago
This is Lily. She’s been accused of drinking her mom’s slushie. Will not be taking any questions at this time. 14/10 (IG: iceedoglilly)
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Dr. Adeene Denton
5 days ago
"Scientists don't want you to know-" Buddy there are so many things I, as a scientist, want you to know and the only thing stopping me from writing more papers and posts about it and then starting a podcast to tell you even MORE things is that I am limited by hours in the day
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Elias Friman
5 days ago
Is distal gene activation by enhancers inherently different from promoter-proximal activation? We propose not. But both cohesin and cooperativity are important aspects of how transcription is affected. Happy to share our recent preprint (thread below) 1/
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.05.06.723196v1
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Jamie McKelvie
5 days ago
So one for Fast, one for Furious, and then two focused on their lesser known family members, Slow and Calm
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I wish I could share this with my father. He said as a French Canadian that the CH in the middle of the rink he interpreted as "Center Hice"
5 days ago
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HABS!!!!!!!!
5 days ago
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Happy Mother’s Day to the most important person in our lives
6 days ago
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Benoit Bruneau
Prof Gavin Yamey
7 days ago
It’s refreshing to see a Congressional Committee calling out Jay Bhattacharya for his anti-vaccine stances, using clear, direct language
democrats-energycommerce.house.gov/sites/evo-su...
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this was fun. First one was the random one. Second I asked for nucleosomes.
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7 days ago
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Benoit Bruneau
Flexpost Malone
7 days ago
No (eyes roll back in head. Feet start levitating off the ground. Clouds roll in) pæŘķÏñĠ
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Wowza
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7 days ago
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At the Weinstein last night: 3D printed jello shots!
7 days ago
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Benoit Bruneau
Axel Visel
7 days ago
Here is the paper:
www.science.org/doi/10.1126/...
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Cis-regulatory evolution shapes facial diversity in birds and mammals
Facial shape diversity in birds and mammals arises from conserved developmental programs tuned by divergent regulatory landscapes.
https://www.science.org/doi/10.1126/sciadv.aec2511
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Benoit Bruneau
Melanie Walsh
8 days ago
The author sent me a copy, and it's really something to behold in person.
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At the Weinstein, out for dinner in Manhattan with current and former Bruneau and Srivastava lab members
8 days ago
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Benoit Bruneau
AliciaDWright
8 days ago
🤷🏻♀️ RP1 . Science-Driven Research Project (RP1) NIH I guess it is a US only, no international collaborations 🤔
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Science-Driven Research Project (RP1) | Grants & Funding
https://grants.nih.gov/funding/activity-codes/RP1
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@j-muncie-vasic.bsky.social
killing it at the Weinstein Cardiovascular Development and Regeneration conference
8 days ago
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Benoit Bruneau
Alexis Verger 🧬🧫🧪
9 days ago
#RIP
Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor
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Benoit Bruneau
Alexis Verger 🧬🧫🧪
9 days ago
#RIP
Pierre Chambon (1931-2026) via
@alainberetz.bsky.social
one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes
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Benoit Bruneau
Angelo Iulianella
9 days ago
Pierre Chambon made seminal contributions to transcriptional regulation, Hox genes, retinoid signaling, and his group was among the earliest to adopt mouse knockout technology. He trained many mouse developmental geneticists. Sad to hear of his passing.
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Benoit Bruneau
Simon Fisher
9 days ago
This Is Just To Say We have desk-rejected the manuscript that you submitted and which you were probably hoping would be sent for peer-review Forgive us it represents an insufficient advance so incremental and so much better suited for a specialist journal
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Views from the Weinstein meeting locale
9 days ago
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Benoit Bruneau
Berna Devezer
9 days ago
Counterpoint: Meetings, service, email, grading, talks, data analysis are no less work than writing. It's allocation of available resources, not self-sabotage. Coffee is good for you actually. Learning to manage overload takes time. Hard projects sometimes require a block of time. We're people.
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Great catching up with old friends at the Weinstein meeting
9 days ago
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Benoit Bruneau
Development
9 days ago
Are you currently at the Weinstein Cardiovascular Development & Regeneration Conference?
@weinsteinconf.bsky.social
Development Editors,
@benoitbruneau.bsky.social
and
@kenposs.bsky.social
, are present - do make sure that you chat to them about publishing with us.
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Benoit Bruneau
John Prensner
10 days ago
Major new work by the
#TransCODE
Consortium out today in
@nature.com
. Read all about our efforts to shed light onto the forgotten areas of the human proteome.
#Microproteins
#Peptideins
#DarkProteome
This was a huge global collaboration, in part funded via
#NIH
www.nature.com/articles/s41...
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Expanding the human proteome with microproteins and peptideins - Nature
A large-scale proteomics analysis of the dark proteome by the TransCODE Consortium reveals many translated non-canonical open reading frames to encode microproteins and peptideins.
https://www.nature.com/articles/s41586-026-10459-x
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Benoit Bruneau
Eugene Day, DSc
10 days ago
I don't believe this question has a reasonable generic answer beyond "At least one, and not too many tiny ones."
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Benoit Bruneau
Christian Mosimann
10 days ago
#WeinsteinConf2026🫀
- first session in, every single talk has slides with red-green LUTs in fluorescent pictures. 6-8% of us face color vision issues, especially for red-green. Alternative, more visible color combos are easily implemented. As scientists, we can do better.
#WeTheColorBlind
#devbio
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Adventure Time: Fin & Jake's Red Gem Dilemma
ALT: Adventure Time: Fin & Jake's Red Gem Dilemma
https://static.klipy.com/ii/8ce8357c78ea940b9c2015daf05ce1a5/b8/d2/9gn3dQe1.gif?hh=242&ww=498&mp4=LcoC3JeRO1TUWGovjPvz&webm=f124MXsDhr2HDslsZE
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Benoit Bruneau
Vijay Ramani
10 days ago
Delighted to share our lab's latest (w/ inimitable
@genophoria.bsky.social
) in final form at
@nature.com
. Enormous lift by Sean Wang,
@palindromephd.bsky.social
&
@martyyang.bsky.social
to address extensive & constructive reviewer comments & see this through. (1/n)
www.nature.com/articles/s41...
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Pervasive and programmed nucleosome distortion on single chromatin fibres - Nature
An analytical pipeline called Iteratively Defined Lengths of Inaccessibility (IDLI) maps the genome-wide occupancy of a range of nucleosome types and shows that most nucleosomes exhibit programmed ‘di...
https://www.nature.com/articles/s41586-026-10418-6
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heartbreaking piece about a life lost. These quotes I totally get: "Crittenden said her current state of grief is more like having a handicap that the rest of the body adjusts for and accommodates.”
www.washingtonpost.com/style/2026/0...
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He wrote about their daughter’s sudden death. Then his wife did the same.
For journalists Danielle Crittenden and David Frum, processing their grief meant telling Miranda’s story, in an essay and in a new memoir, “Dispatches From Grief.”
https://www.washingtonpost.com/style/2026/05/06/dispatches-from-grief-danielle-crittenden-memoir/
10 days ago
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well this should be fun...
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11 days ago
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Benoit Bruneau
The Obama Foundation
12 days ago
Where were you the first time you saw Star Wars?
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Reto Fiolka
11 days ago
@aqlm.bsky.social
Quite reasonable requests…
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one item of note: Oakland Police does not and will not cooperate in any way with ICE
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11 days ago
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Benoit Bruneau
MyPet Health by Vetcation
15 days ago
In 2015, the Los Angeles SPCA gave their annual National Hero Dog award to a tabby cat named Tara. Yes, you read that right, a cat was given a dog award.
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this thread wins best in show
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11 days ago
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Benoit Bruneau
Cooperstreaming ♿️
11 days ago
Am I perfect? No. But am I trying to be better? Also no.
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Harry Turtledove
12 days ago
Headline of the day *****
www.independent.co.uk/tv/news/croc...
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Police airlift crocodile from river on suspicion of eating missing businessman
A crocodile has been helicoptered out of a river in South Africa after police suspected it of eating a missing person. The ‘highly dangerous and complex’ operation came at the end of a week-long searc...
https://www.independent.co.uk/tv/news/crocodile-airlifted-south-africa-river-missing-businessman-video-b2970111.html
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