Benoit Bruneau
@benoitbruneau.bsky.social
📤 5640
📥 2027
📝 1723
Cardiac developmental biologist. Oakland and San Francisco. Hi friends! 🇨🇦
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Benoit Bruneau
Monica
about 3 hours ago
Cry more, whiny asses... Taylor Swift has donated $1 million dollars to the AHA. From the American Heart Association: 🫶 Thank you, Taylor Swift, for your generous gift! We remain "Fearless" in our relentless commitment to prevent heart disease and stroke. Every donation we receive is an honor.
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e.w. niedermeyer
about 4 hours ago
my festive spirit amidst our grimly stupid reality (2025)
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BWJones
about 4 hours ago
Pancreatic cancer is still one of the deadliest cancers. However, there are promising strategies currently under investigation that have been delayed or harmed because of the Trump administration and Elon Musk's DOGE. CDMRP cuts left no money for many forms of cancer research including pancreatic.
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Gladstone Institutes
about 7 hours ago
Have you seen our latest Science in Seconds video? Seth Shipman and his team recently identified seven new retrons from environmental bacteria by sampling soil and water in nature
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Science in Seconds | Researchers Discover New Bacterial Immune Systems
Seth Shipman and his team recently identified seven new retrons from environmental bacteria by sampling soil and water in nature.
https://bit.ly/48HlZ79
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such sad new. Any impending death is tragic. This one hits home. I wish his family courage.
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about 7 hours ago
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Kingfisher & Wombat
1 day ago
This is just a note to say that I have eaten the falcon in a widening gyre and that you were probably saving for anarchy Forgive me it was delicious so rough and full of passionate intensity
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Job Dekker
1 day ago
Exciting new paper out!
@allanaschooley.bsky.social
and Sergey Venev led this project that let to the discovery of two chromosome folding programs: one inherited via mitotic chromosomes and one mitotic inherited through the cytoplasm!
www.nature.com/articles/s41...
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Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm - Nature Cell Biology
Schooley et al. find that mitotically bookmarked loci drive a transient chromosome folding state during G1 entry that is subsequently modulated by factors inherited through the cytoplasm.
https://www.nature.com/articles/s41556-025-01828-1
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Benoit Bruneau
Kerry is Now Just Crabby (and Inclusive) 🚲
2 days ago
Move deliberately and fix things
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Tadaa!
2 days ago
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Courtney Milan
2 days ago
I really think that people not knowing how to learn things and then think about them is a huge problem.
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Robert Reich
2 days ago
Casual reminder that the myth of “pulling yourself up by your bootstraps” is a cruel hoax designed to convince poor people from all walks of life that the injustices they face are a result of their own actions, rather than an oppressive system rigged against them.
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Rabih Alameddine
2 days ago
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Pretty sure I just saw
@rbreich.bsky.social
walk into my local breakfast place. Don’t want to bug him on a Sunday morning, but cool!
2 days ago
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Ansela Corsino
2 days ago
Heated Rivalry is a Crave production, from Canada. HBO is just a distributor. I really wish people would stop attributing anything in the production of this show to HBO.
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again a ludicrous article from Megan McCardle on employment discrimination of "younger White men who hadn’t had time to gain the skills and experience that might have compensated for their melanin deficiency" Let alone that 50% of the population are female...
www.washingtonpost.com/opinions/202...
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Opinion | The diversity overcorrection in the workplace
Discrimination against young White men was an open secret in hiring.
https://www.washingtonpost.com/opinions/2025/12/21/diversity-hiring-white-men/
2 days ago
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watching Palm Royale, which is so much glamorous fun, with such a cast. But in the end of episode 5, Carol Burnett eclipses all the previous episodes, and much of quality tv comedy, in 30 seconds
3 days ago
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AI has its uses, but in the end it’s not silicon but protein and lipids that do the best and final analysis
3 days ago
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This is the news we should be focused on “was seen chasing a woman around the village and trying to eat oranges from a Christmas wreath”“The goat also attempted to munch on safety equipment from the back of the officer’s car. “Apparently it’s not very nice,” one of the officers can be heard saying”
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3 days ago
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KJ Shepherd
3 days ago
It's your birthday, Duane.
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Andrew Hardaway
3 days ago
Happy 1st of your kids being at home all the time for 16 days straight - day for those who celebrate!
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paul khruangbin (Dan Lehner)
4 days ago
no idea if this will be a good movie or not, I’m just ecstatic to see a poster like this for an upcoming movie — peak of the artform, IMO
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ending (almost) the academic year by accepting a ms for publication in
@dev-journal.bsky.social
(I'm an editor). A nice stocking stuffer for these folks...
4 days ago
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Benoit Bruneau
James Pirruccello 🌉
4 days ago
We did a deep dive into aortic stenosis genetics, and took first steps to understand the genetics behind normal human variation in flow across the aortic valve.
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Scorpion peppers. Challenge not really accepted.
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4 days ago
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It's The Weekend 😌
4 days ago
Ladies and gentlemen... the weekend. (also: you are important and are not alone 🧡)
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Jennifer Davis
4 days ago
I love academia, half your coworkers left yesterday evening and won't be back until Jan 6, the other half will frantically try to contact you at 8am on New Year's Day
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Jesse Shapiro
4 days ago
Preprint now, submit to journal in January
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Shino Kany
4 days ago
We’re excited to share our new Nature Genetics paper examining the genetic architecture of aortic valve function and aortic stenosis. We used deep learning of cardiac MRI and MTAG to study disease biology long before clinical diagnosis.
nature.com/articles/s41...
1/10
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Olé! Miss! >>> Ole Miss
4 days ago
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I so relate to frog and toad, but this one takes the cake
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4 days ago
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Accepted ms on modeling human atrial disease posted
@dev-journal.bsky.social
just now. Congratulations to
@irfankathiriya.bsky.social
@jsauce7.bsky.social
and team!
@gladstoneinst.bsky.social
@ucsfanesthesia.bsky.social
journals.biologists.com/dev/article-...
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Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease
While atrial septal defects (ASDs) and atrial fibrillation (AF) present differently, there is evidence that they share some genetic basis. Here, we used directed differentiation of human induced pluri...
https://journals.biologists.com/dev/article-abstract/doi/10.1242/dev.205173/370129/Reduced-TBX5-dosage-undermines-developmental?redirectedFrom=fulltext
4 days ago
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Genes & Development
4 days ago
📽 G&D Tapes 📽 G&D Author, Jon Muncie-Vasic tells us about their new study in #genesdev that defines the role of MEF2C in cardiac tract development. Read the full story here: ➡️
https://genesdev.cshlp.org/content/39/23-24/1451.abstract
Jon Muncie-Vasic
Benoit Bruneau
Gladstone Institutes
#genesdev
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Current Biology
4 days ago
HAPPY HOLIDAYS TO ALL OF YOU!🎄✨
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ERA Commons giving me 404s. Any known reason?
5 days ago
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John Prensner
7 days ago
Wow this is a seriously serious supplementary figure from
@cellpress.bsky.social
today. Panels A through UU. I get that Cell likes to minimize the number of supplementary figures. But is this really what is happening here?
www.cell.com/cell/fulltex...
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Job Dekker
6 days ago
A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists!
www.nature.com/articles/s41...
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An integrated view of the structure and function of the human 4D nucleome - Nature
The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...
https://www.nature.com/articles/s41586-025-09890-3
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"do better the next time" is the new NSF grant review feedback
www.science.org/content/arti...
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NSF pares down grant-review process, reducing influence of outside scientists
Memo cites overburdened staff, but some say move also aims to elevate White House priorities
https://www.science.org/content/article/nsf-pares-down-grant-review-process-reducing-influence-outside-scientists
7 days ago
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Benoit Bruneau
Xela Hart
8 days ago
@davewhamond.bsky.social
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Frog and Toad Bot
7 days ago
“But Toad,” said Frog, “I AM happy. I am very happy. This morning when I woke up, I felt good because the sun was shining. I felt good because I was a frog. And I felt good because I have you for a friend. I wanted to be alone. I wanted to think about how fine everything is.”
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today has really gone up to 11. RIP Rob Reiner.
8 days ago
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Dominique Baker
8 days ago
Let me understand you correctly, governments can care that people are being murdered?
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WeRateDogs
8 days ago
This is Rose. She's paralyzed in both her back legs from being hit by a car as a stray. But when she sees her wheelchair harness come out, she knows it's time to walk and roll. 14/10 (IG: twopawrose)
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The Verge
8 days ago
Fallout season 2 is streaming one day early
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Fallout season 2 is streaming one day early
See you in New Vegas.
https://buff.ly/KpiUMyx
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Happy birthday on what would have been her 54th.
8 days ago
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Ryan
10 days ago
With this piece of bread on the ground in Ottawa, Canada and the one below in Perth, Australia,
@drstip.bsky.social
and I have successfully created an Earth sandwich. The hot dog vs sandwich debate is concluded. If the Earth is sandwiched, everything is a sandwich. HAPPY EARTH SANDWICH DAY!
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Day one
9 days ago
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why in the world did the name/word "Hoobastank" just enter my brain?
9 days ago
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Benoit Bruneau
#BruceSterling
9 days ago
They used to "laugh and call him names." Now they're all dead
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Roxane Gay
9 days ago
May he be graced with peace and may the memories of all who died in such a cruel way be a blessing.
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truly amazing paper led by current postdoc Lisa Iwamoto-Stohl. "To our knowledge, this represents the first systematic evidence of proteomic asymmetry between sister blastomeres in the 2-cell mouse embryo."
pubmed.ncbi.nlm.nih.gov/41344326/
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Fertilization triggers early proteomic symmetry breaking in mammalian embryos - PubMed
While non-mammalian embryos often rely on spatial pre-patterning, mammalian development has long been thought to begin with equivalent blastomeres. However, emerging evidence challenges this. Here, using multiplexed and label-free single-cell proteomics, we identify over 300 asymmetrically abundant …
https://pubmed.ncbi.nlm.nih.gov/41344326/
11 days ago
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