Stark, dark, but that’s it. I would say support your friends and colleagues and preserve what we can

Yeah on my way to work one that had just dropped off a rider quickly backed into traffic and just stayed there. 🙄

they're talking about goalie aggression, but nothing tops Ron Hextall

what the heck is going on with the goalies in this game? Five goals in 15 minutes?

Today in neighborhood bumper stickers #bugsky #insectthursday

NEW: A serious staffing shortage — of the Trump admin's own making — is delaying the agency's ability to send billions to universities around the country, leaving labs reeling in the meantime. “I thought we were at rock bottom”, a senior NIH official said. “We are below rock bottom now.”

New in #GENETICS from @hainerlab.bsky.social: The nucleosome remodelers esBAF and INO80 selectively influence subcompartment identity and enhancer–promoter communication at key regulatory loci during higher-order chromatin organization in mice. 🔗 buff.ly/0eU5xg0

To commemorate the lab’s 25 th, lab gifted me a lovely photo montage (man I look young in the older ones) and an awesome personalized guitar strap!

Burrowing owls turn food delivery into a work of art. 🪶

Jason Collins died of glioblastoma today. He was a wonderful person. This is awful

This thread firstly upends how we think things work, and also illustrates the power of modeling paired with experimentation

Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇

This is Lily. She’s been accused of drinking her mom’s slushie. Will not be taking any questions at this time. 14/10 (IG: iceedoglilly)

"Scientists don't want you to know-" Buddy there are so many things I, as a scientist, want you to know and the only thing stopping me from writing more papers and posts about it and then starting a podcast to tell you even MORE things is that I am limited by hours in the day

Is distal gene activation by enhancers inherently different from promoter-proximal activation? We propose not. But both cohesin and cooperativity are important aspects of how transcription is affected. Happy to share our recent preprint (thread below) 1/ www.biorxiv.org/content/10.6...

So one for Fast, one for Furious, and then two focused on their lesser known family members, Slow and Calm

I wish I could share this with my father. He said as a French Canadian that the CH in the middle of the rink he interpreted as "Center Hice"

HABS!!!!!!!!

Happy Mother’s Day to the most important person in our lives

It’s refreshing to see a Congressional Committee calling out Jay Bhattacharya for his anti-vaccine stances, using clear, direct language democrats-energycommerce.house.gov/sites/evo-su...

this was fun. First one was the random one. Second I asked for nucleosomes.

No (eyes roll back in head. Feet start levitating off the ground. Clouds roll in) pæŘķÏñĠ

Wowza

At the Weinstein last night: 3D printed jello shots!

Here is the paper: www.science.org/doi/10.1126/...

The author sent me a copy, and it's really something to behold in person.

At the Weinstein, out for dinner in Manhattan with current and former Bruneau and Srivastava lab members

🤷🏻‍♀️ RP1 . Science-Driven Research Project (RP1) NIH I guess it is a US only, no international collaborations 🤔

@j-muncie-vasic.bsky.social killing it at the Weinstein Cardiovascular Development and Regeneration conference

#RIP Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor

#RIP Pierre Chambon (1931-2026) via @alainberetz.bsky.social one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes

Pierre Chambon made seminal contributions to transcriptional regulation, Hox genes, retinoid signaling, and his group was among the earliest to adopt mouse knockout technology. He trained many mouse developmental geneticists. Sad to hear of his passing.

This Is Just To Say We have desk-rejected the manuscript that you submitted and which you were probably hoping would be sent for peer-review Forgive us it represents an insufficient advance so incremental and so much better suited for a specialist journal

Views from the Weinstein meeting locale

Counterpoint: Meetings, service, email, grading, talks, data analysis are no less work than writing. It's allocation of available resources, not self-sabotage. Coffee is good for you actually. Learning to manage overload takes time. Hard projects sometimes require a block of time. We're people.

Great catching up with old friends at the Weinstein meeting

Are you currently at the Weinstein Cardiovascular Development & Regeneration Conference? @weinsteinconf.bsky.social Development Editors, @benoitbruneau.bsky.social and @kenposs.bsky.social, are present - do make sure that you chat to them about publishing with us.

Major new work by the #TransCODE Consortium out today in @nature.com. Read all about our efforts to shed light onto the forgotten areas of the human proteome. #Microproteins #Peptideins #DarkProteome This was a huge global collaboration, in part funded via #NIH www.nature.com/articles/s41... 1/

I don't believe this question has a reasonable generic answer beyond "At least one, and not too many tiny ones."

#WeinsteinConf2026🫀- first session in, every single talk has slides with red-green LUTs in fluorescent pictures. 6-8% of us face color vision issues, especially for red-green. Alternative, more visible color combos are easily implemented. As scientists, we can do better. #WeTheColorBlind #devbio

Delighted to share our lab's latest (w/ inimitable @genophoria.bsky.social) in final form at @nature.com. Enormous lift by Sean Wang, @palindromephd.bsky.social & @martyyang.bsky.social to address extensive & constructive reviewer comments & see this through. (1/n) www.nature.com/articles/s41...

heartbreaking piece about a life lost. These quotes I totally get: "Crittenden said her current state of grief is more like having a handicap that the rest of the body adjusts for and accommodates.” www.washingtonpost.com/style/2026/0...

well this should be fun...

Where were you the first time you saw Star Wars?

@aqlm.bsky.social Quite reasonable requests…

one item of note: Oakland Police does not and will not cooperate in any way with ICE

In 2015, the Los Angeles SPCA gave their annual National Hero Dog award to a tabby cat named Tara. Yes, you read that right, a cat was given a dog award.

this thread wins best in show

Am I perfect? No. But am I trying to be better? Also no.

Headline of the day ***** www.independent.co.uk/tv/news/croc...