Our new preprint is out: www.biorxiv.org/content/10.6... We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs. A reminder of why bias-aware evaluation matters!

🎉 Wrapping up 2025 with EpiCrossBorders! A year of breakthroughs, cross-border exchanges, multiple publications & vibrant outreach. Next stop: 2026 Symposium in Edinburgh + new workshops & theses submissions Thank you to all who made this possible. 🌐 #Epigenetics #PhDprogram #Sciencecollaboration

Excited to share new manuscript on histone acylations, exploring how H4K16 acylations regulate inter and intranucleosomal interactions and how they confer resilience to metabolic challenges in vivo. Thanks to all authors +1 author @sandrani.bsky.social Enjoy 👇👇 www.sciencedirect.com/science/arti...

👉 Chromatin Summer School 2026 – Apply Now! Join us in Munich 17–29 August 2026 for an immersive program on chromatin biology: 🔬 Expert lectures 🧪 Hands-on training 🤝 Global networking Open to 14 PhD students worldwide (sponsorship available) 👉 Apply here: bit.ly/4oGDR8f #ChromatinBiology

Please RT 📧 Registration open for ➡️"Summer School on Chromatin Biology" Our 2 weeks hands on expedition 🧪👩‍💻August 2026. 3. edition. Learn CUT@Tag, CUT@Run, ChIPseq, ATACseq AND to analyse your own data at @helmholtzmunich.bsky.social Daily letures by experts in the field ! ▶️ shorturl.at/jrA8i

🌍 The #HelmholtzMunich Talent Forum 2025 brought together exceptional early-career scientists in #epigenetics & nucleic acids research to foster exchange, collaboration & research excellence. 👩‍🔬👨‍🔬 👉 t1p.de/3dsix @boyanbonev.bsky.social @epihmgu.bsky.social #TalentForum

The Helmholtz Munich Talent Forum (Nov 18–19) brought 8 emerging global talents in epigenetics & nucleic acids research to our Neuherberg Campus! Inspiring talks, a keynote by @boyanbonev.bsky.social & vibrant networking—science at its best! bit.ly/4o2ftxr

Science thrives through engagement and this weekend proved it! The “Stem Cell Stories” exhibition @ Deutsches Museum showcased the power of outreach. A shout-out to our EpiCrossBorders students, who played a key role in connecting with the public and sparking curiosity. #ScienceOutreach

Wrapping up a great weekend of “Stem Cell Stories” at the Deutsches Museum. Science doesn’t exist in isolation. We are committed to engaging with society, exchanging ideas, and building trust through transparency. Let’s keep the conversation going. #ScienceOutreach #Epigenetics #AIinBiomedicine

We are ready! Our team have been working all day to set up the interactive exhibition "Stem Cell Stories" at Deutsches Museum. Join us and explore the world of cell identities. 📅Fri 14 - Sun 16 Nov 📍Deutsches Museum, Munich ⏲️09:00 - 17:00 daily Find out more: bit.ly/4p9Jk8m

Fantastic breakthrough for Type 1 Diabetes by @helmholtzmunich.bsky.social

Our EpiCrossBorders students have helped turn science into stories! Stem Cell Stories - an exhibition on cell identitity (Nov 14 - 16) at Deutsches Museum. Also, don't miss the panel discussion on Friday 14 Nov: AI in biomedicine and the ethical questions it raises (in German). bit.ly/4qMnb1y

James D. Watson died on Thursday in East Northport, N.Y., on Long Island. He was 97. www.nytimes.com/2025/11/07/s...

Decoding #Oat Diversity for a #Climate-Resilient Future🌾 This study provides valuable insights into how oats adapt to their environments – paving the way for more robust, climate-smart crops. 👉 t1p.de/gmmgb @leibniz-gemeinschaft.de @natureportfolio.nature.com @tum.de

“Translating complex science into something simple, yet meaningful is never easy.” 💬 Our #EpiCrossBorders PhD researchers are learning just that — turning #epigenetics into connection, curiosity & conversation at the Deutsches Museum. 📍14–16 Nov | #StemCellStories #SciComm #PhDLife

The #MBioSys25 keynote lectures by Prof Caroline Dean (@johninnescentre.bsky.social) and Prof @elowitzlab.bsky.social (Caltech) are now online! Watch (or revisit!) these two inspiring talks on gene regulation & functional genomics, available for free on our channel www.youtube.com/@MolecularBi...

Great discussions & attendance @helmholtzmunich.bsky.social in our yearly #Epigenetics Spotlight meeting organised by @robertife.bsky.social and myself - thanks all for coming, our long-distance guests Giacomo ad Marc !! and all attendants for fantastic discussions - see you next year 🥳

Stem Cell Stories @ Deutsches Museum Meet the EpiCrossBorders students behind the scenes—bringing science to life! 🧬 Join us Nov 14–16 | Free entry 🎤 AI & ethical implications in research roundtable: Nov 14, 18:30 #StemCellStories #NextGenScience #EpiCrossBorders #ScienceComm #DeutschesMuseum #AI

Happy to have a "full house" at the Munich Epigenetics Spotlight meeting today @helmholtzmunich.bsky.social 2 excellent keynotes by Gicomo Cavalli and @marcbuhler.bsky.social as well 4 talks from the strong and very active Munich #epigenetics community ! @epihmgu.bsky.social @crc1064.bsky.social

🧬 From 14–16 Nov, join us at the #DeutschesMuseum for “Stem Cell Stories” — an interactive exhibition on stem cells, identity & epigenetics. 🎙️ Roundtable discussion on #AI in stem cell research & its ethical challenges on 📅14 Nov ⏲️18:30. #StemCells #Epigenetics #AIinBiomedicine #HelmholtzMunich

Thank you all. And we hope to see you again in 2027 for the premier conference on gene regulation in Latin America!

#Jobalert 🚨: Please RT ! Looking for a #PhD student for exciting project on the interphase between epigenetics and cellular metabolism: How do (nuclear) metabolic enzymes reguate chromatin function ? #epigenomics, #epigenetics, #metabolism www.helmholtz-munich.de/en/ife/job-o...

For me Bryan‘s “Decoding the Nucleosome” (Cell 1993) is a seminal review and unfortunately often forgotten in the chromatin field. Really a giant of epigenetics !

🚨 New Review Out 🚨 Thrilled to share our latest review in Molecular Nutrition & Food Research: “Dad’s Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health” 👉 lnkd.in/g8_VWKCp

Massive thanks to my incredible co-authors @annesopepin.bsky.social, Katharina, Johannes, @robertife.bsky.social, Martin & the wonderful @epitep.bsky.social for your warm collaboration, sharing of ideas, and support to make this paper a reality.

#Preprint alert! 📣 We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that #MLL2 controls gene expression in both #ESC and upon #differentiation by facilitating the #enhancer like activity of #LINE1 elements www.biorxiv.org/cgi/content/...

Last week part of our group attended the Gordon Research Conference Histone and DNA Modifications. Such a great combination of cool science and networking! #newPI

....and special thanks to ‪@annaknoer.bsky.social‬ and @annesopepin.bsky.social‬ for organizing the Gordon Research School (GRS) the last 2 days. 🇮🇹 Great talks by trainees and exciting keynote by ‪@jamiehackett.bsky.social‬

Gordon Conference “Histone and DNA modifications” Started today with keynote by @helink.bsky.social ‬ 5️⃣ days of exciting science in beautiful Tuscany 🇮🇹 shorturl.at/hBjyT

Our review on ➡️"Histone modifications in development" is out 🍾 in 🔖 Development @dev-journal.bsky.social urnal.bsky.social‬ Read more about histone tail and globular domain modifications during development: journals.biologists.com/dev/article/...

Please RT ! 5️⃣ days left to register. Gordon Conference “Histone and DNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup !!! >25 talks will be chosen from abstracts. Submit yours ➡️ shorturl.at/hBjyT

Please RT ! Gordon Conference “Histone and RNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Theme: Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup. >20 talks will be chosen from abstracts. Submit yours soon ➡️ shorturl.at/hBjyT

Here’s our latest study on human gastruloids: www.science.org/doi/10.1126/... With the Surani lab, we combine imaging, scRNA-seq and genetic perturbation to investigate the emergence of amnion-&PGC-like cells. Congrats to Jitesh Neupane, Gabriele Lubatti and all co-authors for their great work!

🌟 SAVE THE DATE: Talent Forum 2025! 🗓️ November 18–19 📍 @www.helmholtz-munich.de‬, Germany Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research! Apply by July 31 for a speaker spot —travel & accommodation covered. 🔜 Website coming soon!

Are you a postdoc or PhD student interested in Epigenetics and Epitranscriptomics? Join us for the GRS on Histone and DNA (&RNA 😉) Modifications! 🗓 When: July 19-20, 2025 📍 Where: Lucca, Italy 🧬 Deadline for talks: April 13, 2025 Register now! GRS: shorturl.at/5SiOW GRC: shorturl.at/ReNSG

Happy to speak today at the Fox Chase (FCC) Epigenetics Symposium in Philadelphia. Thanks to John for the invite ! #CEI2025Symp

WOW! We received >1100 applications, from 97 countries, for our #Epigenetics Summer Internship! 🚀 New record! Thanks to all applicants for the enthusiasm 🫂 7 students will be soon selected for a 2-month adventure @www.helmholtz-munich.de. Good luck to all applicants! Results in mid/late-March. 🤞

Interested in Chromatin modifications & epigenetics in health, disease and development? Apply now to our GRC and GRS. Many speaker slots still to be chosen from abstracts! www.grc.org/histone-and-...

How can we improve gene regulatory network inference from noisy scRNA-seq data? Our new review in @molsystbiol.org explores the latest methods integrating prior knowledge to enhance reliability. Plus, some suggestions on how to improve benchmarking! www.embopress.org/doi/full/10....

Are you a postdoc or PhD student interested in Histone and DNA modifications? Join us for the GRS on Histone and DNA Modifications! 🗓 When: July 19-20, 2025 📍 Where: Lucca, Italy A great opportunity to present your work, engage in discussions, and network with peers. 🔗 Register now! Register here

🏃‍♀️🏃ONLY 1 WEEK LEFT! INTERNSHIP OPPORTUNITY @www.helmholtz-munich.de! 🚀Join 1 of the 7 available teams, gain hands-on experience, and contribute to groundbreaking science on #epigenetics, #AI, #StemCells & more. Apply: www.helmholtz-munich.de/en/epigeneti... 🗓️ APPLICATION DEADLINE: 17th February

We have 7 projects available for undergrad & master students interested in #AI, #chromatin and #epigenetics. 🧬The Chromatin Dynamics and Epigenetics Lab, led by @robertife.bsky.social, will host an intern during this summer. 🤩Do you want to be her/him? 👉 www.helmholtz-munich.de/en/epigeneti...

Please RS/RT. #GordonConference "Histone and DNA Modifications" Program is now online 🍾 #epigenetics #chromatin #histones 20.-25. July. Il Ciocco 🇮🇹 Register now: ➡️ shorturl.at/AtAjz Exciting speaker lineup, many slots for talks selected from abstracts

Thanks to everyone for joining our Mini-Symposium 🎊 2️⃣0️⃣ 🍾years of Schneider lab 🇩🇪 @mpi-ie.bsky.social 🇫🇷Strasbourg 🇩🇪 @www.helmholtz-munich.de Was great to welcome so many lab members, catch up, listen to your science and careers! Wouldnt have been possible without all of you !!!

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

Lab minigolf party to farewell Natalie after a wonderful 2 years as a summer student, honours student and RA. Seems only fitting she won the tournament! (I wont disclose who came last…) The future is bright for you Natalie, we’ll miss you but wish you all the best with @robertife.bsky.social! 🧪🧬👩‍🔬

🌟 STEM CELLS: THE GENIES OF THE BODY Exhibition #DeutschesMuseum by our scientists @www.helmholtz-munich.de. Hands-on experience, games, arts, expert insights and an inspiring round table discussion. Great weekend of science! 🔬🧬#StemCells #epigenetics #ScienceCommuication👩 ‍🔬

Congratulations to Kurt Schmoller @IFE @www.helmholtz-munich.de to his #ERC grant 🥳 So well deserved! #cellsize #mitochondria #modelorganisms 👇 www.helmholtz-munich.de/en/ife/resea...

As part of our #DeutschesMuseum exhibition on #StemCells (you can still visit - today is the final day !) we had yesterday a discussion round on "Stem Cells & Ethics" with scientists from #HelmholtzMunich, ethicists and journalists. Thanks to everyone taking part ! Lots to learn !

This morning: First ❄️ and ☀️on campus #HelmholtzMunich Great start into the 1. day on #Bluesky !