Rob Schneider
@robertife.bsky.social
📤 679
📥 110
📝 21
https://www.helmholtz-munich.de/en/ife
reposted by
Rob Schneider
Antonio Scialdone
3 days ago
Our new preprint is out:
www.biorxiv.org/content/10.6...
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs. A reminder of why bias-aware evaluation matters!
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Hidden sampling biases inflate performance in gene regulatory network inference
Accurate reconstruction of gene regulatory networks (GRNs) from single-cell transcriptomic data remains a major methodological challenge. Recent machine learning approaches, particularly graph neural ...
https://www.biorxiv.org/content/10.64898/2025.12.19.695616v1
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Rob Schneider
EpiCrossBorders
5 days ago
🎉 Wrapping up 2025 with EpiCrossBorders! A year of breakthroughs, cross-border exchanges, multiple publications & vibrant outreach. Next stop: 2026 Symposium in Edinburgh + new workshops & theses submissions Thank you to all who made this possible. 🌐
#Epigenetics
#PhDprogram
#Sciencecollaboration
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Excited to share new manuscript on histone acylations, exploring how H4K16 acylations regulate inter and intranucleosomal interactions and how they confer resilience to metabolic challenges in vivo. Thanks to all authors +1 author
@sandrani.bsky.social
Enjoy 👇👇
www.sciencedirect.com/science/arti...
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H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations
Histone modifications play crucial roles in genome function. However, how chromatin integrates physiological and metabolic responses at the molecular …
https://www.sciencedirect.com/science/article/pii/S1097276525009712
7 days ago
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
17 days ago
👉 Chromatin Summer School 2026 – Apply Now! Join us in Munich 17–29 August 2026 for an immersive program on chromatin biology: 🔬 Expert lectures 🧪 Hands-on training 🤝 Global networking Open to 14 PhD students worldwide (sponsorship available) 👉 Apply here:
bit.ly/4oGDR8f
#ChromatinBiology
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Summary - Summer School on Chromatin Biology: A Hands-On Expedition
https://bit.ly/4oGDR8f
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Please RT 📧 Registration open for ➡️"Summer School on Chromatin Biology" Our 2 weeks hands on expedition 🧪👩💻August 2026. 3. edition. Learn CUT@Tag, CUT@Run, ChIPseq, ATACseq AND to analyse your own data at
@helmholtzmunich.bsky.social
Daily letures by experts in the field ! ▶️
shorturl.at/jrA8i
18 days ago
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reposted by
Rob Schneider
Helmholtz Munich
about 1 month ago
🌍 The
#HelmholtzMunich
Talent Forum 2025 brought together exceptional early-career scientists in
#epigenetics
& nucleic acids research to foster exchange, collaboration & research excellence. 👩🔬👨🔬 👉
t1p.de/3dsix
@boyanbonev.bsky.social
@epihmgu.bsky.social
#TalentForum
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
about 1 month ago
The Helmholtz Munich Talent Forum (Nov 18–19) brought 8 emerging global talents in epigenetics & nucleic acids research to our Neuherberg Campus! Inspiring talks, a keynote by
@boyanbonev.bsky.social
& vibrant networking—science at its best!
bit.ly/4o2ftxr
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reposted by
Rob Schneider
EpiCrossBorders
about 1 month ago
Science thrives through engagement and this weekend proved it! The “Stem Cell Stories” exhibition @ Deutsches Museum showcased the power of outreach. A shout-out to our EpiCrossBorders students, who played a key role in connecting with the public and sparking curiosity.
#ScienceOutreach
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
about 1 month ago
Wrapping up a great weekend of “Stem Cell Stories” at the Deutsches Museum. Science doesn’t exist in isolation. We are committed to engaging with society, exchanging ideas, and building trust through transparency. Let’s keep the conversation going.
#ScienceOutreach
#Epigenetics
#AIinBiomedicine
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
about 1 month ago
We are ready! Our team have been working all day to set up the interactive exhibition "Stem Cell Stories" at Deutsches Museum. Join us and explore the world of cell identities. 📅Fri 14 - Sun 16 Nov 📍Deutsches Museum, Munich ⏲️09:00 - 17:00 daily Find out more:
bit.ly/4p9Jk8m
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Fantastic breakthrough for Type 1 Diabetes by
@helmholtzmunich.bsky.social
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about 1 month ago
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reposted by
Rob Schneider
EpiCrossBorders
about 2 months ago
Our EpiCrossBorders students have helped turn science into stories! Stem Cell Stories - an exhibition on cell identitity (Nov 14 - 16) at Deutsches Museum. Also, don't miss the panel discussion on Friday 14 Nov: AI in biomedicine and the ethical questions it raises (in German).
bit.ly/4qMnb1y
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reposted by
Rob Schneider
Alejandro Montenegro
about 2 months ago
James D. Watson died on Thursday in East Northport, N.Y., on Long Island. He was 97.
www.nytimes.com/2025/11/07/s...
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James Watson, Who Helped Discover the Structure of DNA, Is Dead at 97
https://www.nytimes.com/2025/11/07/science/james-watson-dead.html
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reposted by
Rob Schneider
Helmholtz Munich
about 2 months ago
Decoding
#Oat
Diversity for a
#Climate-Resilient
Future🌾 This study provides valuable insights into how oats adapt to their environments – paving the way for more robust, climate-smart crops. 👉
t1p.de/gmmgb
@leibniz-gemeinschaft.de
@natureportfolio.nature.com
@tum.de
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reposted by
Rob Schneider
EpiCrossBorders
about 2 months ago
“Translating complex science into something simple, yet meaningful is never easy.” 💬 Our
#EpiCrossBorders
PhD researchers are learning just that — turning
#epigenetics
into connection, curiosity & conversation at the Deutsches Museum. 📍14–16 Nov |
#StemCellStories
#SciComm
#PhDLife
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reposted by
Rob Schneider
Molecular Biosystems Conference
2 months ago
The
#MBioSys25
keynote lectures by Prof Caroline Dean (
@johninnescentre.bsky.social
) and Prof
@elowitzlab.bsky.social
(Caltech) are now online! Watch (or revisit!) these two inspiring talks on gene regulation & functional genomics, available for free on our channel
www.youtube.com/@MolecularBi...
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Molecular Biosystems Conference
Youtube Home Page for the Molecular Biosystems Conference (molbiosystems.com), the premier Latin American meeting on gene regulation.
https://www.youtube.com/@MolecularBiosystemsConference
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reposted by
Rob Schneider
ME Torres-Padilla
2 months ago
Great discussions & attendance
@helmholtzmunich.bsky.social
in our yearly
#Epigenetics
Spotlight meeting organised by
@robertife.bsky.social
and myself - thanks all for coming, our long-distance guests Giacomo ad Marc !! and all attendants for fantastic discussions - see you next year 🥳
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reposted by
Rob Schneider
EpiCrossBorders
2 months ago
Stem Cell Stories @ Deutsches Museum Meet the EpiCrossBorders students behind the scenes—bringing science to life! 🧬 Join us Nov 14–16 | Free entry 🎤 AI & ethical implications in research roundtable: Nov 14, 18:30
#StemCellStories
#NextGenScience
#EpiCrossBorders
#ScienceComm
#DeutschesMuseum
#AI
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Happy to have a "full house" at the Munich Epigenetics Spotlight meeting today
@helmholtzmunich.bsky.social
2 excellent keynotes by Gicomo Cavalli and
@marcbuhler.bsky.social
as well 4 talks from the strong and very active Munich
#epigenetics
community !
@epihmgu.bsky.social
@crc1064.bsky.social
2 months ago
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
3 months ago
🧬 From 14–16 Nov, join us at the
#DeutschesMuseum
for “Stem Cell Stories” — an interactive exhibition on stem cells, identity & epigenetics. 🎙️ Roundtable discussion on
#AI
in stem cell research & its ethical challenges on 📅14 Nov ⏲️18:30.
#StemCells
#Epigenetics
#AIinBiomedicine
#HelmholtzMunich
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reposted by
Rob Schneider
Alejandro Montenegro
3 months ago
Thank you all. And we hope to see you again in 2027 for the premier conference on gene regulation in Latin America!
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#Jobalert
🚨: Please RT ! Looking for a
#PhD
student for exciting project on the interphase between epigenetics and cellular metabolism: How do (nuclear) metabolic enzymes reguate chromatin function ?
#epigenomics
,
#epigenetics
,
#metabolism
www.helmholtz-munich.de/en/ife/job-o...
3 months ago
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For me Bryan‘s “Decoding the Nucleosome” (Cell 1993) is a seminal review and unfortunately often forgotten in the chromatin field. Really a giant of epigenetics !
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4 months ago
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reposted by
Rob Schneider
Dr David Skerrett-Byrne
4 months ago
🚨 New Review Out 🚨 Thrilled to share our latest review in Molecular Nutrition & Food Research: “Dad’s Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health” 👉
lnkd.in/g8_VWKCp
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LinkedIn
This link will take you to a page that’s not on LinkedIn
https://lnkd.in/g8_VWKCp
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reposted by
Rob Schneider
Dr David Skerrett-Byrne
4 months ago
Massive thanks to my incredible co-authors
@annesopepin.bsky.social
, Katharina, Johannes,
@robertife.bsky.social
, Martin & the wonderful
@epitep.bsky.social
for your warm collaboration, sharing of ideas, and support to make this paper a reality.
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reposted by
Rob Schneider
Rada-Iglesias Lab
5 months ago
#Preprint
alert! 📣 We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that
#MLL2
controls gene expression in both
#ESC
and upon
#differentiation
by facilitating the
#enhancer
like activity of
#LINE1
elements
www.biorxiv.org/cgi/content/...
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MLL2 facilitates long-range gene regulation through LINE1 elements
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 d...
https://www.biorxiv.org/cgi/content/short/2025.08.10.669526v1
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reposted by
Rob Schneider
Cristina Viéitez
5 months ago
Last week part of our group attended the Gordon Research Conference Histone and DNA Modifications. Such a great combination of cool science and networking!
#newPI
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....and special thanks to @annaknoer.bsky.social and
@annesopepin.bsky.social
for organizing the Gordon Research School (GRS) the last 2 days. 🇮🇹 Great talks by trainees and exciting keynote by @jamiehackett.bsky.social
5 months ago
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Gordon Conference “Histone and DNA modifications” Started today with keynote by
@helink.bsky.social
5️⃣ days of exciting science in beautiful Tuscany 🇮🇹
shorturl.at/hBjyT
5 months ago
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Our review on ➡️"Histone modifications in development" is out 🍾 in 🔖 Development
@dev-journal.bsky.social
urnal.bsky.social
Read more about histone tail and globular domain modifications during development:
journals.biologists.com/dev/article/
...
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6 months ago
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Please RT ! 5️⃣ days left to register. Gordon Conference “Histone and DNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup !!! >25 talks will be chosen from abstracts. Submit yours ➡️
shorturl.at/hBjyT
6 months ago
0
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Please RT ! Gordon Conference “Histone and RNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Theme: Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup. >20 talks will be chosen from abstracts. Submit yours soon ➡️
shorturl.at/hBjyT
8 months ago
0
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reposted by
Rob Schneider
Antonio Scialdone
9 months ago
Here’s our latest study on human gastruloids:
www.science.org/doi/10.1126/...
With the Surani lab, we combine imaging, scRNA-seq and genetic perturbation to investigate the emergence of amnion-&PGC-like cells. Congrats to Jitesh Neupane, Gabriele Lubatti and all co-authors for their great work!
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The emergence of human primordial germ cell–like cells in stem cell–derived gastruloids
3D human gastruloids mimic gastrulation and postgastrulation development, forming the three germ layer derivatives and hPGCLCs.
https://www.science.org/doi/10.1126/sciadv.ado1350
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
9 months ago
🌟 SAVE THE DATE: Talent Forum 2025! 🗓️ November 18–19 📍
@www.helmholtz-munich.de
, Germany Showcase your research and network with global talents in
#Epigenetics
& Nucleic Acids Research! Apply by July 31 for a speaker spot —travel & accommodation covered. 🔜 Website coming soon!
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reposted by
Rob Schneider
Anna Knörlein
10 months ago
Are you a postdoc or PhD student interested in Epigenetics and Epitranscriptomics? Join us for the GRS on Histone and DNA (&RNA 😉) Modifications! 🗓 When: July 19-20, 2025 📍 Where: Lucca, Italy 🧬 Deadline for talks: April 13, 2025 Register now! GRS:
shorturl.at/5SiOW
GRC:
shorturl.at/ReNSG
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Happy to speak today at the Fox Chase (FCC) Epigenetics Symposium in Philadelphia. Thanks to John for the invite !
#CEI2025Symp
10 months ago
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
10 months ago
WOW! We received >1100 applications, from 97 countries, for our
#Epigenetics
Summer Internship! 🚀 New record! Thanks to all applicants for the enthusiasm 🫂 7 students will be soon selected for a 2-month adventure
@www.helmholtz-munich.de
. Good luck to all applicants! Results in mid/late-March. 🤞
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reposted by
Rob Schneider
Cheryl Arrowsmith
10 months ago
Interested in Chromatin modifications & epigenetics in health, disease and development? Apply now to our GRC and GRS. Many speaker slots still to be chosen from abstracts!
www.grc.org/histone-and-...
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reposted by
Rob Schneider
Antonio Scialdone
11 months ago
How can we improve gene regulatory network inference from noisy scRNA-seq data? Our new review in
@molsystbiol.org
explores the latest methods integrating prior knowledge to enhance reliability. Plus, some suggestions on how to improve benchmarking!
www.embopress.org/doi/full/10....
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Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data | Molecular Systems Biology
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
https://www.embopress.org/doi/full/10.1038/s44320-025-00088-3
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reposted by
Rob Schneider
Anna Knörlein
11 months ago
Are you a postdoc or PhD student interested in Histone and DNA modifications? Join us for the GRS on Histone and DNA Modifications! 🗓 When: July 19-20, 2025 📍 Where: Lucca, Italy A great opportunity to present your work, engage in discussions, and network with peers. 🔗 Register now! Register here
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2025 Histone and DNA Modifications (GRS) Seminar GRC
The 2025 Gordon Research Seminar on Histone and DNA Modifications (GRS) will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
https://www.grc.org/histone-and-dna-modifications-grs-conference/2025/
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
11 months ago
🏃♀️🏃ONLY 1 WEEK LEFT! INTERNSHIP OPPORTUNITY
@www.helmholtz-munich.de
! 🚀Join 1 of the 7 available teams, gain hands-on experience, and contribute to groundbreaking science on
#epigenetics
,
#AI
,
#StemCells
& more. Apply:
www.helmholtz-munich.de/en/epigeneti...
🗓️ APPLICATION DEADLINE: 17th February
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reposted by
Rob Schneider
Epigenetics at Helmholtz Munich
11 months ago
We have 7 projects available for undergrad & master students interested in
#AI
,
#chromatin
and
#epigenetics
. 🧬The Chromatin Dynamics and Epigenetics Lab, led by
@robertife.bsky.social
, will host an intern during this summer. 🤩Do you want to be her/him? 👉
www.helmholtz-munich.de/en/epigeneti...
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Please RS/RT.
#GordonConference
"Histone and DNA Modifications" Program is now online 🍾
#epigenetics
#chromatin
#histones
20.-25. July. Il Ciocco 🇮🇹 Register now: ➡️
shorturl.at/AtAjz
Exciting speaker lineup, many slots for talks selected from abstracts
11 months ago
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Thanks to everyone for joining our Mini-Symposium 🎊 2️⃣0️⃣ 🍾years of Schneider lab 🇩🇪
@mpi-ie.bsky.social
🇫🇷Strasbourg 🇩🇪
@www.helmholtz-munich.de
Was great to welcome so many lab members, catch up, listen to your science and careers! Wouldnt have been possible without all of you !!!
11 months ago
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Please RS/RT.
#GordonConference
on "Histone and DNA Modifications"
#epigenetics
#chromatin
20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now
www.grc.org/histone-and-...
about 1 year ago
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reposted by
Rob Schneider
Mel Eckersley-Maslin
about 1 year ago
Lab minigolf party to farewell Natalie after a wonderful 2 years as a summer student, honours student and RA. Seems only fitting she won the tournament! (I wont disclose who came last…) The future is bright for you Natalie, we’ll miss you but wish you all the best with
@robertife.bsky.social
! 🧪🧬👩🔬
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🌟 STEM CELLS: THE GENIES OF THE BODY Exhibition
#DeutschesMuseum
by our scientists
@www.helmholtz-munich.de
. Hands-on experience, games, arts, expert insights and an inspiring round table discussion. Great weekend of science! 🔬🧬#StemCells
#epigenetics
#ScienceCommuication👩
🔬
about 1 year ago
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Congratulations to Kurt Schmoller @IFE
@www.helmholtz-munich.de
to his
#ERC
grant 🥳 So well deserved!
#cellsize
#mitochondria
#modelorganisms
👇
www.helmholtz-munich.de/en/ife/resea...
about 1 year ago
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As part of our
#DeutschesMuseum
exhibition on
#StemCells
(you can still visit - today is the final day !) we had yesterday a discussion round on "Stem Cells & Ethics" with scientists from
#HelmholtzMunich
, ethicists and journalists. Thanks to everyone taking part ! Lots to learn !
about 1 year ago
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This morning: First ❄️ and ☀️on campus
#HelmholtzMunich
Great start into the 1. day on
#Bluesky
!
about 1 year ago
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