Help please! We need to do some large(ish) cell culture inhibiting E-cadherin with a monoclonal antibody. Does anyone have the DECMA-1 hybridoma cell line so we could purify our own antibody? or a similar monoclonal that would do the job. Any help greatly appreciated, just DM me. Please repost!

1/8 Inside your body lies something ancient. Our @pnas.org paper uncovers the deep unicellular prehistory of blood cell types. See paper and video. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @prbb.org @csic.es @csicdivulga.bsky.social pnas.org/doi/10.1073/...

We are allocating an extra €15 million in humanitarian assistance to support the response to the Ebola outbreak affecting the DRC and Uganda. Safeguarding public health remains our priority as diseases do not stop at borders and cooperation is essential. link.europa.eu/BwQRMc

Szczegóły i zapisy pod linkiem: forms.office.com/e/wFjkPV4P5v

Do you have a manuscript with reviews from another journal? We can use them to fast track a decision on your submission. Read more journals.biologists.com/dev/pages/jo...

#RNAsky #epigenetics

SETD2 aids gene definition by acting on both its beginning and end - yet in a gene specific way. Proud of this new work from the lab! @uam-ibmib.bsky.social @emboreports.org #chromatin #RNAbiology

Our paper (@stoplab.bsky.social), in collaboration with the Nojima lab (@pol2rna.bsky.social @chiheron.bsky.social), on the role of chromatin modifier SETD2 at both ends of the transcriptional cycle, is now published in @emboreports.org 🪅 (1/5) link.springer.com/article/10.1...

Finally published at long last (at least in the pre-view version). Explore the wild and woolly world of archaeal histones! Interactive archaeal histone graph incluced rdcu.be/fdFjv. Congratulations to first author Shawn Laursen

Are you excited by virology? Would you like to do a PhD? Three fantastic opportunities are available to do joint PhDs between @cvrinfo.bsky.social and @pirbrightinst.bsky.social Details in the thread below - please share! Deadline 8th May 2026, fully funded for UK Home students (1/4)

The Angel of Death did not find Chuck Norris. Chuck Norris found the Angel of Death. Remembering the best (fictional) martial arts fight ever captured on film: www.youtube.com/watch?v=NlTy...

Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...

This Friday at the @uam-ibmib.bsky.social seminar: Katarzyna Klonowska from the Institute of Biooganic Chemistry PAS in Poznan will give a talk on mutation landscape in tumour suppressor gene syndromes - join us!

We’re recruiting! Three-year, fully funded #postdoc opportunity: pancreatic cancer #epigenetics & potential new treatments (funded by @ncn.gov.pl & @dfg.de ). Collaboration with @akispapantonis.bsky.social, University of Göttingen (OPUS-LAP). See the ad & contact me! drive.google.com/file/d/1vrFd...

Scientists have found a little RNA molecule – small enough to potentially form spontaneously, yet sophisticated enough to copy itself – that cd explain how life on Earth arose. Thanks @edogia.bsky.social of the @philholliger.bsky.social lab! blog.sciencemuseum.org.uk/in-the-begin...

It took a while but it’s finally published! The GAP activity of SEAC (GATOR) is a metabolic switch that allows cells to quickly respond to changes in amino acid levels, both for inhibition and reactivation.

my head is still spinning from EMBO Selfish Genetic Elements this week! incredible gamut of mostly "non-model" species gives us appreciation and insights into diversity of unusual chromosome dynamics, selfish genes and weird sex. tx @lucasoldini.bsky.social @laurarossevo.bsky.social tanja schwander!

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n

Are you a DNMT3 enthusiast wondering how they achieve specificity at CpG islands during development? And why is DNMT3B specifically required for methylation on the inactive X? We set out to dissect the mechanism, now published in Genes & Development genesdev.cshlp.org/content/earl... [1/12]

A vanishing star births a black hole—without the fireworks | Science | AAAS @science.org 🔭🧪 www.science.org/content/arti...

Thrilled to announce that I’ve just opened my research lab at @helmholtz-hiri.bsky.social ! A huge thank you to my mentor Roi Avraham (and lab members!) for the incredible training and support that made this possible.

Excited to share our latest study in Nature Communications ✨ We map how cells clear DNA damage–stalled RNA polymerase II using a stepwise TFIIH → ubiquitin/VCP mechanism, keeping transcription and genome stability on track. Paper: www.nature.com/articles/s41... #Genomics #DNADamage #CellBiology

Attention RNA biology and antisense therapy folks: this is HUUUUUUGE!!! Termination windows as therapeutic opportunity!

I’m super excited to be opening a lab at WEHI. We’ll be focussing on how double-stranded RNA is regulated in cells, how failures in these pathways drive disease and new therapies to manipulate inflammatory responses to RNA. #newPI #RNAsky

Our new preprint on SMCHD1! We’ve shown SMCHD1’s ATPase activity is critical for function in vivo, and excitingly a new DNA binding domain neighbouring the ATPase domain activates the enzymatic function, which is important for normal chromatin binding. urldefense.com/v3/__https:/...

I've joined the Editorial Board of @plosbiology.org PLOS Biology is the flagship #PLOS journal in the Life Sciences. I'm looking forward to handling terrific cell biology papers for them. #CellBiology

No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition. Which just makes me want to share it again: www.nature.com/articles/d41...

The way UK govt funds science is in the midst of a major transition, with creation of a much more direct link between government priorities & UKRI research funding. My attempt to set in context the biggest upheaval in UK science funding policy since the 1980s: softmachines.org?p=3252

Discuss #RNA 3' ends and their regulation at the EMBO Workshop "RNA 3' ends and beyond" in #Oxford, United Kingdom, 7–11 September 2026. Deadline: 4 May 2026 https://meetings.embo.org/event/26-rna3#RNA#Oxford#EMBORNA3EndsBeyond #RNAsky #LifeSciences #meeting #EMBOevents 🧪

Sign up now for the EMBO Workshop "#RNA metabolism: Perspective from physiology to brain disorder" in Darjeeling, India, 25–28 October 2026. Deadline: 15 May 2026 https://meetings.embo.org/event/26-rna-metabolism#RNA#EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪

Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...

Join us; We have an opening for a BBSRC-funded 3-year postdoc position to investigate the mechanisms of mRNA-specific translational regulation of the innate immune system. #Postdoc #RNA #RBP #MolecularBiology #Virology #RNASky #AcademicJobs hrwebapp.qub.ac.uk/tlive_webrec...

How do compartmentalization & loop extrusion organize eukaryotic genomes beyond classical model organisms? Hi-C analysis of silkworm chromosomes by Drinnenberg, Muller, Mirny et al reveals new combination of these mechanisms, and a new, secluded “S” compartment link.springer.com/article/10.1...

Washington Post reporter laid off while freezing in a war zone by one of the world’s richest people.

Both MRC and BBSRC responsive modes now withdrawn until further notice. Existing applications unlikely to succeed (late 2025 round expecting 1-5% success rate). Listen, I get that UKRI wants to pivot. But killing both at once is devastating. Let's hope at least one opens by summer... #AcademicSky

Have a look at this fantastic meeting and save the date! The “RNA in Physiology and Disease” conference, hosted by @gensocuk.bsky.social, will take place 7–9 September 2026 in Newcastle, UK. genetics.org.uk/events/rna-i...

... and we're off. Great kick-off meeting for the start of the ERC synergy GeneMotors project. So much energy and enthusiasm. @ceesdekker.bsky.social @erc.europa.eu

Which one is in you experience a more reliable and robust kit for sterility test (i.e in CAR-T samples): Sartorius or Thermofisher?

Our journals Development, Journal of Cell Science, Disease Models & Mechanisms and Biology Open are pleased to be media partners for a number of @embo.org and @embl.org conferences, workshops and courses during 2026. See the full calendar of events at www.embl.org/about/info/c....

Still some time to register to this great meeting! Great science and great location for a very affordable registration cost!

Great discussion and excellent engagement from participants in this pilot to involve ECRs in peer review. A very promising start for this initiative at @embopress.org and @reviewcommons.org. Thanks to all the postdocs for the the enthusiasm and thoughtful contributions.

Let's try this #AcademicSky 1 fav, 1 funny, strange, or unexpected scientific anecdote about a paper, a scientist, a fact, hoping that some will be new to you.

Arianna Esposito Verza, @andrea-musacchio.bsky.social et al describe the long-sought-after mechanism of Bora dependency of PLK1 activation by Aurora A kinase during mitotic entry Another #RefereedPreprint ℅ @reviewcommons.org link.springer.com/article/10.1...

RFKJr's principal accomplishment as the nation's health guardian.

We are looking for PhD students or Postdocs with an interest in developing and using new methods for functional genetics following our recent work 👉 rdcu.be/e05Oo and academic.oup.com/nar/article/52

Decoding influenza virus: From polymerase mechanisms to translational therapeutics www.sciencedirect.com/science/arti...

You want to DO something? Lead a rally for science in your city/town/village. Stop whining on the internet and do something.

The boss tries to run one simple PCR just to chip in a bit, and this is the reaction from the lab 😂