New paper alert! 🚨 We report two Cypriot XP-A patients with a mild phenotype caused by the homozygous c.389G>A (p.R130K) variant. 👉 The variant affects splicing, leading to reduced XPA mRNA/protein but residual NER activity. www.sciencedirect.com/science/arti...

📢 ERCC1-hepatorenal syndrome is defined as a severe, multisystem DNA repair disorder associated with high morbidity and mortality, including an elevated cancer risk. 🧬 @luijsterburglab.bsky.social www.nature.com/articles/s41...

Dive into the step-by-step choreography of transcription-coupled DNA repair. In our new review published in Nature Cell Biology, we explore what we know and what’s next in this exciting field of research! www.nature.com/articles/s41...

Happy to share I have been promoted to Full Professor of Transcription and DNA Repair! Huge thanks to all current and former Luijsterburg Lab members. Your hard work, dedication, and inspiring spirit made this possible! 💥🧬🙏 www.luijsterburglab.org

Are transcription-associated histone marks involved in restoring transcription after DNA damage in human cells? Read the surprising outcome in our new preprint 👇 www.biorxiv.org/content/10.1...

Very proud of this international collaborative team effort published in EJHG defining ERCC1-hepatorenal syndrome as a severe multisystem DNA repair disorder with high mortality and pediatric liver cancer risk. Thanks to all families and collaborators. www.nature.com/articles/s41...

📢 Only 2 more days left until the early bird registration deadline! Secure your spot and join us at the 8th EU-US Conference on Endogenous DNA Damage and Repair!

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

It was wonderful to have our lab symposium yesterday, filled with great science, new ideas, good company, and delicious food. What a pleasure it is to work with such a fantastic group of people!

Our letter-to-the-editor providing evidence that ARK2N is not a core factor in transcription-coupled DNA repair is now online in PNAS | www.pnas.org/doi/10.1073/...

Mark your calendar: the next Egmond DNA repair meeting will take place in 2026 from April 19 - 24! You can pre-register to receive announcement here: forms.lumc.nl/lumc2/Egmond Registration will open by June 2025/

Lovely Christmas party with the @luijsterburglab.bsky.social ! Looking forward to great science with this amazing group in 2025.

Our review on the recently discovered transcription-coupled DPC repair pathway is out in Trends in Cell Biology. Yet another wonderful collaboration with @cjcarnie.bsky.social and Steve Jackson.

It's a wrap! The 12th 3R+3C meeting in Fukuoka was amazing. Looking forward to the next edition!

Leaving Kyoto for the 3R+3C meeting in Fukuoka! Looking forward to great science, catching up with old friends, and making new ones.

Putting together packs of transcription and Chromatin people - Nominate others to add! go.bsky.app/5zgpZfg

En route to the 3R&3C meeting in Fukuoka, but first some time for sightseeing in Kyoto!

Happy to share our new paper with Goran Kokic and the Svejstrup lab in Cell! We show that STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair. Great teamwork by Diana, Marta and Paula! www.cell.com/cell/fulltex...