Are you interested in working on related projects? 🌱 The Knipscheer lab at the Hubrecht Institute (Utrecht, the Netherlands) has openings for a postdoc and a PhD position. Apply here: www.hubrecht.eu/jobs

Thrilled that our work is now finally out in Nature Comms! rdcu.be/eG3vP We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres. Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position: jobs.dkfz.de/en/jobs/1679... You'll learn a lot and it'll be fun and interesting! #DKTK @dkfz.bsky.social @lmumuenchen.bsky.social

I am very excited to share the newest paper of the lab, a huge amount of work led by our talented PhD student Maxime Galloy, in close collaboration with Andréanne Blondeau, our dedicated research assistant for 10 years! 🙌 www.cell.com/molecular-ce...

Now peer reviewed and in its final form @natcomms.nature.com www.nature.com/articles/s41...

🥳Congratulations, Shubo! 🥂👏What a fantastic start to your scientific career! Shubo Zhao @jstingele.bsky.social receives Promotion Award from the Münchner Universitätsgesellschaft: www.genzentrum.uni-muenchen.de/news-events/... MUG prizes for LMU early-career researchers www.lmu.de/en/newsroom/...

Cytarabine has been the mainstay for AML treatment for over 50 years. This chemotherapy can lead to problems with movement and balance. Here we explain this neurotoxic side-effect. www.nature.com/articles/s41... Work led by Jia-Cheng Liu, Donpeng Wang and Elsa Callen and terrific collaborators!

🚨 Check out our latest review in #MolecularCell! We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis. 👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social 👉📰 authors.elsevier.com/a/1lDFm3vVUP...

Delighted to share that the results of my main postdoc project are now published in @nature.com 🔗 doi.org/10.1038/s415...

A PhD position is open in my group here in Heidelberg. We'll use cool primary cell models of osteosarcoma and genetic screens to understand and overcome mechanisms of clinically acquired drug resistance. It'll be a blast! karriere.klinikum.uni-heidelberg.de/index.php?ac...

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

One week left to register and submit abstracts for being considered for talks at our upcoming #EMBO Meeting "RNA Meets Protein Degradation" in Vienna! Check out the program with a fantastic line-up of speakers, including keynotes by Rachel Green and Manu Hedge. meetings.embo.org/event/25-rna...

FINAL DEADLINE ENDING: Only one day left to submit your abstract for the EMBO | EMBL Symposium The ageing genome: from mechanisms to disease www.embl.org/about/info/c...

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.   Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...

Incredibly timely and informative review article @cp-cell.bsky.social by @jstingele.bsky.social and team on #RNA Damage www.cell.com/cell/fulltex...

Happy to share our review on the cellular responses to RNA damage 🥂 Congrats to joined first authors Jacqueline Cordes & @shubozhao.bsky.social www.cell.com/cell/fulltex...

Register now for The Ageing Genome: from Mechanisms to Disease conference. Amazing line-up of speakers and great opportunities for presenting your work and discussing with leaders in the field #EESAgeing @embl.org @cecad.bsky.social www.embl.org/about/info/c...

Very proud of this. It’s both the end and beginning of something new for me. My last paper in @dkcortez.bsky.social lab and my first co-corresponding author. Also truly a great supergroup including @freudlab.bsky.social @tmweaver.bsky.social and Roberts lab www.nature.com/articles/s41...

In Praise of Peer Review As an Editor of the journal Development, I often hear complaints about peer review. We all know the problems - from lengthy review times to requests for seemingly unnecessary experiments. I agree with many of these complaints. Katherine Brown (Executive Editor of…

📣 SAVE THE DATE: EMBO workshop SUMOylation: from discovery to translation. 22-25 Sept 2025. La Grande Motte (France) Registrations will open soon: coming-soon.embo.org/w25-59

🧠🧠🧠Could the brain influence evolution? Check out our super hot preprint: A single pair of neurons that sense temperature controls genetic changes in the inheritable genome by triggering transposons that change the genome for generations to come www.biorxiv.org/content/10.1...

Hello, Bluesky! To kick things off here, we’re excited to share: The SLFN11 story continues! We combined cryo-EM and biochemical assays to explain how phosphorylation regulates SLFN11´s tRNA cleavage and ssDNA binding activities. Check out our new paper here www.nature.com/articles/s41... + movie

An absolute must read! Congratulations on a great review on how these intriguing lesions are removed!

Our review on the recently discovered transcription-coupled DPC repair pathway is out in Trends in Cell Biology. Yet another wonderful collaboration with @cjcarnie.bsky.social and Steve Jackson.

Happy to share our latest work🍾 🥳 PhD student Sophie Dürauer discovered together with many wonderful collaborators that the ubiquitylation of DNA-protein crosslinks promotes their cleavage by SPRTN more than 100-fold 🧬🔧

Happy to share our new paper with Goran Kokic and the Svejstrup lab in Cell! We show that STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair. Great teamwork by Diana, Marta and Paula! www.cell.com/cell/fulltex...

The peer-reviewed version of our paper is out! Thanks to all co-authors, editor and reviewers for the smooth process 🤓🎉 And don’t miss the chromatin haiku! www.cell.com/molecular-ce...

Hi BlueSky! It's great to be here. Here's a handy Starter Pack of DNA repair & genome stability groups that I found so far go.bsky.app/NvFWKvL

First post here! New paper from the lab! Profound synthetic lethality between FANCM and SMARCAL1: www.cell.com/molecular-ce...

Very pleased to share our new paper on the translation-coupled resolution of RNA-protein crosslinks @MolecularCell Our first adventure into the resolution of RNA damage was spearheaded by the brilliant Jackie Cordes and Shubo Zhao doi.org/10.1016/j.mo...

Super interesting analysis of the evolutionary aspects of DNA-protein crosslink repair

New preprint from the lab! We traced the dynamic evolutionary history of a DNA repair gene family in Drosophila.   We propose that DNA-protein crosslink repair recurrently coevolves with DNA repeats - check out our coevolutionary “seesaw” model in Fig 6. :)   www.biorxiv.org/content/10.1...