Excited to share a new method developed from my group thats published at Genome Biology. This was an amazing effort by my grad student Linh @linhngk.bsky.social. We developed Topsicle, a method that analyzes long read data for telomere analysis and length measuring. doi.org/10.1186/s130...

Love RNA biology? Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇). PhD student/postdoc position co-supervised by Clemens Plaschka & myself. DM or email us if you’d like to know more! @vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social

I’m super happy to present the first discoveries of the RIKEN-Cambridge Joint Crop Symbiosis Research Team, based in Japan 🇯🇵 doi.org/10.1101/2025... A thread 👇

Really excited to share our latest paper led by @simonaube.bsky.social. Fascinating results examining whether regulatory mutations can lead to adaptation as fast as coding mutations do. #mevosky #evobio #evoSky www.biorxiv.org/content/10.1...

Please re-post: Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo... Abstract deadline: 30 September

New from the lab led by @natrigg.bsky.social. We started by characterizing mRNA in sperm, EVs, and the epithelium across epididymal transit. This revealed evidence that sperm acquire specific mRNAs through fusion with epididymal EVs, which we further established with in vitro co-incubation assays

🚨 Excited to share my main postdoc work from the @jenscs83.bsky.social lab, now out in Cell Reports! 👉 www.sciencedirect.com/science/arti... We dissect how shelterin proteins organize at telomeres in human cancer cells—revealing distinct subcomplexes that maintain chromosome ends. 🧵

Hey Drosophilists: Might you maintain Fuyama's original gynogenetic "gyn-F9" (BDSC #5353) stock in your library? The current stock from Bloomington is not producing progeny with ms(k81) males. Thank you!!!

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...

The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested aprecruit.berkeley.edu/JPF05052

Wonderful (and humble) essay on mentorship by Brandon Gaut, on occasion of Brandon receiving the inaugural Mentorship Award of @genetics-gsa.bsky.social. I hope this will be widely read! academic.oup.com/genetics/art...

piRNAs are essential for transposon silencing in the animal germline. But how do hosts trap transposon sequences in genomic loci that help establish a piRNA response? Looking at a natural transposon invasion, Baptiste Rafanel and Kirsten Senti made some remarkable observations.

last call! submit your abstract by tonight to be selected for one of the many oral presentations at the leading European Transposon Meeting. We are very much looking forward to your contribution and attendance!

The Mathieson Lab at the University of Pennsylvania is hiring a computational postdoc in machine learning and evolutionary biology. Apply with a CV and references: [email protected]. More info: https://saramathieson.github.io/lab #postdoc

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

Is the annotation of viruses in the human genome accurate? We think not. Take a look at our new paper and let us know if you agree! www.science.org/doi/10.1126/...

Now peer reviewed and in its final form @natcomms.nature.com www.nature.com/articles/s41...

🚨Our latest work on selfish centromeres is published @currentbiology.bsky.social 🐭🧬We found that the spindle checkpoint contributes to non-Mendelian segregation! Huge congrats to our lab manager, Zaak Walton, who led the project🎉 Free link: authors.elsevier.com/a/1lQzN3QW8S...

We are looking for a student to continue our work on chromatin evolution: www.nature.com/articles/s41... www.biorxiv.org/content/10.1... The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes. More info: recruitment.crg.eu/content/jobs...

Our latest paper is out: rdcu.be/ev6Ym — one of my favorite projects. It began about 8 years ago when Nobel laureate Torsten Wiesel asked me: what transcription factors regulate new genes? I had no idea then. Now we have some answers.

Pls. share widely Calling all transposon fans & lovers of genetic innovation MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025 → Vibrant & friendly community → Cutting-edge talks from mechanisms to physiology → Plenty of surprises (TEs never stop innovating) submit abstract by July 29

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

I am excited to share the first paper from my postdoc in the Cooper lab. Hopefully, this is useful for anyone working on PEV image quantification in Drosophila. Please reach out if you have any questions or comments, and stay tuned for more updates! academic.oup.com/biomethods/a...

Happy New Year, blue-sci-peeps! My piece in Annual Review of Biophysics on chromatin replication is now available online. doi.org/10.1146/annu... If you have paywall issues, try this link: madhanilab.ucsf.edu/s/annurev-bi...

Jan 1, and my first day as an Asst. Professor at Berkeley. The lab opens in just a few weeks and I am currently staffing at all levels- www.lotuslofgren.com/new-page-1

1/8 Super excited to share my first-author preprint in @jenscs83.bsky.social lab! We measured the shelterin complex stoichiometry and dynamics at telomeres in living cells. Our results re-envisions the architecture of telomeres in human cancer cells. www.biorxiv.org/content/10.1...

Congrats to all the newly elected members of the GSA Board of Directors, including TAGC24 veteran @barrlab.bsky.social genestogenomes.org/new-members-...

Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr

With our lab’s inaugural Blue Sky post we celebrate our latest publication, a review in Nature Reviews Molecular Cell Biology (@natrevmcb.bsky.social) 🥳 Here, we review our current understanding of telomere biology, discussing differences between human and mouse. www.nature.com/articles/s41...

Hello hello! As anyone used an anti-mScarlett antibody? We would like to try and amplify the signal for a chromatin bound protein. Thank you!

First post on bsky. We've updated our preprint about the change in the histone H3 variant on chromatin during Zygotic Genome Activation. Thanks to new experiments by Anusha, it seems like our initial, simplistic idea that the embryo "ran out" of H3 was not right. www.biorxiv.org/content/10.1...

New paper led by @yadirapga.bsky.social! Even though opossums have kids at 0.5 years, they still have typical male-biased mutation (though not quite as high as humans). "Low mutation rate but high male-bias in the germline of a short-lived opossum" www.biorxiv.org/content/10.1...

Another video of a developping drosophila embryo, but this time rotating. I beleive tjis was generated in Python using @maweigert.bsky.social 's spimagine rendering tool. www.nature.com/articles/nbt... 🧪🔬🪰💻

I currently have an opening in my lab for a Laboratory Research Assistant. Potential candidates must have their bachelor's. You can find more information here: hrms.iu.edu/psp/PH1PRD_P...

Totally delightful and delicious Levine Lab holiday party + book exchange/white elephant last night. Here’s what we think you should read this year.

HELLO BLUESKY! First post! The lab just got a new grant! #PackardFellows! Please help us spend this money by joining! We are looking for a Postdoc interested in Developmental Biology, Retrotransposons, Early Embryos and Reproduction & maybe disease! @upenn.bsky.social @pennepigenetics.bsky.social

A little deep dive we did on everyone's favorite domestication gene!

Are you aware of our collection of #Drosophila #history articles? Feel free to suggest more!!!!!!!! droso4public.wordpress.com/history/

Happy to share our latest work🍾 🥳 PhD student Sophie Dürauer discovered together with many wonderful collaborators that the ubiquitylation of DNA-protein crosslinks promotes their cleavage by SPRTN more than 100-fold 🧬🔧

For her PhD work, Carla Bautista in our group discovered that yeast hybrids adapted slower to stressful conditions, and she figured out why. See what she found here. #evolution www.nature.com/articles/s41...

Nicolas Svetec, David Begun, and I wrote a review article about de novo genes. If you are interested in this topic please take a look at this final open-access version at AnnualReviews www.annualreviews.org/content/jour...

For my first post here, I am happy to share that our latest paper is out at #NAR. Thanks for the smooth and constructive reviewing process and the highlight #RNAbiology #TEsky #smallRNAs (1/8) doi.org/10.1093/nar/...

New work on Drosophila centromere evolution led by the amazing @cecilecourret.bsky.social!Thanks to all coauthors and collaborators in the @centromellone.bsky.social lab.

@mcgregorlab.bsky.social and I had the pleasure of writing a dispatch article discussing the latest work from @gavinrrice.bsky.social and @rebeizlab.bsky.social. You can find it over on this link: www.sciencedirect.com/science/arti...

Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬

Telomeric transposons are pervasive in linear bacterial genomes https://www.biorxiv.org/content/10.1101/2024.11.13.623437v1

Thrilled to announce that the EMBO workshop «Mobile Genome» will be back in Heidelberg, Nov 4-7th 2025 @EMBLEvents @EMBO. Registration open soon but you can already register interest. Organized with fantastic colleagues @juliusbrennecke @GonzalezLab_BCN @JoePetersLab www.embl.org/about/info/c...

New paper from the lab now published in MBE: Evolutionary dynamics of pro-inflammatory caspases in primates and rodents! We found some cool stuff about how these immune proteins rapidly evolve, with implications for functional studies 1/n academic.oup.com/mbe/advance-...