New paper from my lab out in NAR. We found that young L1 elements are controlled by SETDB1 and H3K9me3 in human neural progenitor cells via a mechanism independent of HUSH and TRIM28/KZNFs. academic.oup.com/nar/article/...

New Year, New Paper!🎊 Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system www.biorxiv.org/content/10.6... Centerpiece of Jason Chobirko's PhD, talented PhD student co-mentored by Andrew Grimson & me. Really excited about it!🧵

Dear #Drosophila researchers, the year starts with good news! The date and venue for our next meeting is confirmed: June 1st to 3rd at the beautiful Historic Hotel Castle De Palmela in Portugal! Mark the dates, registration will open soon!

Such a #PLEASURE to be involved in this collaboration ! All the #transposon annotated during the project can be visualized in #RepetDB the TE database. #TEsky

So excited to finally be able to share my first paper and the culmination of my PhD work with @felipekteixeira.bsky.social 🪰🔬 www.pnas.org/doi/10.1073/...

Wow, huge congratulations on your ERC Consolidator @leandroquadrana.bsky.social!Truly well-deserved, I’m really happy for you! www.insb.cnrs.fr/fr/personne/...

Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches May 18-22, 2026 Roscoff, France Abstract deadline: January 31, 2026 Apply here: cjm.sb-roscoff.fr/en

JASPAR 2026 is out 🎉 The new release massively expands the TF motif collections and adds a dedicated DeepLearning collection of motifs learned from deep learning models. Database: jaspar.elixir.no Paper (NAR): doi.org/10.1093/nar/... 🧵1/2

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

Membrane #nanotubes are cytoskeletal structures that facilitate intercellular communication. This study shows that polar cell-derived #microtubule nanotubes play a role in #Drosophila #fertilization, creating a channel in the eggshell that facilitates #sperm entry @plosbiology.org 🧪 plos.io/3XwOlvS

Another envelope protein in the human genome. Expressed in the placenta, of course.

And here is the link to access the whole pdf. Enjoy! I strongly believe that focusing on information & computation during Development provides an important framework, that encapsulates the genetic, chemistry & mechanics, but focusses on organisation, dynamics & logic. PDF: tinyurl.com/4hn34t8w

An open webinar on our reproducibility project 'WHAT 400 DROSOPHILA PAPERS Teach Us about Doing Better Science' on December 9th 2PM EEST time (1PM Swiss time). Registration below

Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5

Our lab is actively looking for posdocs and there is NOW an Open Call for Postdoc contracts (3 years) here: www.aei.gob.es/en/announcem...

anybody looking for exciting opportunities in RNA research, with the goal to use and learn state of the art thinking and experimenting: here is a good starting point. Ulrich is an outstanding scientist and natural leader. 👇👇👇👇

Excited to share our new @narjournal.bsky.social paper! Using ReLo and AlphaFold, we described a network of interactions between Drosophila piRNA pathway factors suggesting new links how they coordinate to ensure transposon silencing and genome integrity. academic.oup.com/nar/article/...

Transposon Regulation in the Caenorhabditis elegans Germline and Soma www.biorxiv.org/content/10.1...

Congratulations to Magnus Nordborg of the GMI and @oeaw.bsky.social who, together with Leandro Quadrana and @pierrebaduel.bsky.social, has received an @fwf-at.bsky.social Grant for the project “Genetic and epigenetic determinants of transposon dynamics”. More here: www.oeaw.ac.at/gmi/detail/n...

Our latest pre-print on TE-mediated tandem duplication of the ToxB effector is now online...still a puzzle for us but we think it is in a Helitron! Together with amazing collaborators, Reem Aboukhaddour and Ryan Gourlie #TE #fungi www.biorxiv.org/content/10.1...

piRNA-directed DNA methylation may not be a mammalian invention, but can already be found in the germline of axolotl salamanders Donal O’Carroll and coworkers www.embopress.org/doi/full/10....

TE x ZFP = Evolution! Writing this with Olga @orpsf.bsky.social & Didier @trono-lab.bsky.social was a major highlight of my 🇨🇭sabbatical. Such a treat! 🍫Hope you enjoy it as much as we enjoy piecing it together.

Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

(1/9) Join us in Bern, Switzerland (8–11 Feb 2026) for our EMBO Workshop on Molecular Mechanisms of Selfish Elements and Strategies! Organized with Tanja Schwander, Laura Ross (@laurarossevo.bsky.social) and Axel Imhof. meetings.embo.org/event/26-sel... #EMBOselfishElements #EMBOevents

Some impressions from the rather fabulous #EMBOmobilegenome Mobile Genome meeting in Heidelberg Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, … @events.embl.org The transposon community is going very strong. see you all again in 2027!!

great to be at the #EMBOMobileGenome meeting in Heidelberg with a wonderful bunch of colleagues, speakers and attendees. this meeting is a good reflection of the excitement and collegiality in the transposon field. kindly sponsored by @embo.org

Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner! Congratulations to Vincent and Emilie @igred.fr ! links.springernature.com/f/a/L1ogzL3H...

On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social flies fly! @fly-eds.bsky.social www.cell.com/developmenta...

When transposons jump, genomes diverge - even in cultured cells. I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. 🧬🧵 (1/12)

It is today and tomorrow! #IBENS International Symposium on Epigenetic Inheritance will bring together leading international experts in the field and pay tribute to Vincent Colot and Eric Meyer, two pioneers of epigenetics and eminent colleagues, on the occasion of their retirement.

Love RNA biology? Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇). PhD student/postdoc position co-supervised by Clemens Plaschka & myself. DM or email us if you’d like to know more! @vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social

🌿⚖️ Growth or defense? A new study in Science Advances shows how the PAF1 complex helps plants toggle between growth and immune responses by regulating gene expression. 📖 science.org/doi/10.1126/... 🔬 Collaboration between Wuhan Univesity & @cnrs.fr

Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included. training.institut-curie.org/courses/deve...

Novel insights into the silencing of an understudied transposable element - check out our latest preprint by @jakobschnabl.bsky.social and colleagues

A little late to share, but still thrilled 🤗! What started as two independent stories, one in Clermont-Ferrand (@igred.fr) and one in Cambridge (Hannon’s group @cruk-mi.bsky.social ), turned into a joint adventure to decode how Rhino picks its favorite piRNA clusters. When forces unite… 👇👇👇

Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...

Very excited to have joined the @mpi-ie.bsky.social ! Thank you for the warm welcome 🤩🤩

Nice write up on @joshdubnau.bsky.social's "transposon storm" hypothesis: Alzheimer’s and ALS may be triggered by reawakened viral-like jumping genes that spark inflammation and kill neurons. Antiviral drugs could stop the storm. knowablemagazine.org/content/arti...

The Chromatin And Development lab are hiring a postdoc! Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT! lms.mrc.ac.uk/work/vacanci...

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Complete ape genomes! 🦍🦧 Our closest relatives get the deluxe sequencing treatment, resolving the most complex & often most interesting parts of the genome. Happy to make a tiny contribution alongside @panpan100.bsky.social to awesome teamwork & fantastic resource. www.nature.com/articles/s41...

💥🥳 At long last, our latest paper is out! Gag proteins of endogenous retroviruses are required for zebrafish development www.pnas.org/doi/10.1073/... Led heroically by Sylvia Chang & @jonowells.bsky.social A study which has changed the way I think of #transposons! No less! 🧵 1/n

👉 IMBA is hiring a Junior Group Leader in the molecular life sciences. Apply by May 18: imba.science/beagroupleader #hiring #biology #research #groupleader #europe

DFAM (database of transposable elements) 3.9 is out! A lot of cool new stuff and a special update for Drosophila melanogaster... 1/2 #Transposon #DFAM

🎉 so excited to share my first first-author paper is out in @Nature.com, from my PhD work in the Gallio Lab! we uncover the neurobiological mechanisms that drive the evolution of temperature preference behavior in flies of the genus Drosophila 👇 go.nature.com/4i1VQn9

Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs. www.cell.com/cell-genomic...

A selfish gene in Drosophila has met its match: Trailblazer. “An innovation in host responses to escalating genomic conflicts” by @emilianomarti.bsky.social & Amanda Larracuente highlights work from @peiwei-chen.bsky.social et al in PNAS. FREE till May 24 at authors.elsevier.com/a/1ktQOcQbJF...