🆕 New paper out with Jean-Luc Imler and Rune Hartmann in EMBO journal. We dissect mechanisms of antiviral immunity and how STING is activated by FADD and DREDD during viral infection in Drosophila melanogaster. link.springer.com/article/10.1...

Integrated small and long RNA sequencing reveals piRNA mediated transposon repression during human oogenesis www.nature.com/articles/s41...

🚨📢📄 Article in press in Genome Biology doi.org/10.1186/s130... We introduce panREPET, a reference-free pipeline to detect shared transposable element (TE) insertions across pangenomes and retrace their evolutionary dynamics #TEsky 🧵👇

Excited to announce the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination (Sept 21–25, 2026): cjm.sb-roscoff.fr/en/conferenc... Organized by @laurarossevo.bsky.social and myself.

#JobOffer 💼 Professeur en stabilité du génome 📍Institut Jacques Monod 📆 1e septembre 2026 Les candidatures sont ouvertes jusqu'au 3 avril 2026 16h🔗 u-paris.fr/recrutement-...

Bacterial Schlafen proteins mediate phage defence (new work from @anemudraia.bsky.social and @artemnemudryi.bsky.social labs) www.nature.com/articles/s41... Schlafens are an ancient, mechanistically conserved family of tRNA-targeting immune effectors.

🌱 🚨Postdoc position – Plant Chromatin Biology (Strasbourg) Grob and Jullien Lab - details attached 📅 Apply by March 30, 2026 📩 [email protected] Please share with anyone who might be interested! #Postdoc #PlantScience #Epigenetics #Chromatin

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

📢 PhD position in our lab! (MSCA COFUND) About dystrophin in Drosophila muscle progenitor cells 🧬🪰 #PhDPosition #DevBio #Drosophila #StemCells For candidates from outside France or have lived in France <12 months in the last 3 years. More info 👇 (Project #16) www.muskle.eu/recruitment/

The (Yoav) Voichek lab has opened its gates at the Weizmann Institute, and is actively recruiting students and researchers at all levels - come explore gene regulation and computational genomics in a fun, friendly sprouting lab 🤗🥼⚗️🧪 www.weizmann.ac.il/plants/voichek

We were all very sad to learn the death of Pierre Capy. Pierre was a professor at University Paris Saclay, in the 1990s, he started a group working on the evolutionary genomics of transposable elements; this group is still very active today. He was a great teacher, mentor, and colleague.

Pierre Capy était un généticien, un drosophiliste, un acteur majeur dans l'essor de la génétique des éléments transposables en France. Très impliqué dans l'administration de la vie scientifique, il a aussi été directeur du laboratoire LEGS (actuel @EGCE), et un des fondateurs en 2016 de @IDEEV.

New paper from my lab out in NAR. We found that young L1 elements are controlled by SETDB1 and H3K9me3 in human neural progenitor cells via a mechanism independent of HUSH and TRIM28/KZNFs. academic.oup.com/nar/article/...

New Year, New Paper!🎊 Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system www.biorxiv.org/content/10.6... Centerpiece of Jason Chobirko's PhD, talented PhD student co-mentored by Andrew Grimson & me. Really excited about it!🧵

Dear #Drosophila researchers, the year starts with good news! The date and venue for our next meeting is confirmed: June 1st to 3rd at the beautiful Historic Hotel Castle De Palmela in Portugal! Mark the dates, registration will open soon!

Such a #PLEASURE to be involved in this collaboration ! All the #transposon annotated during the project can be visualized in #RepetDB the TE database. #TEsky

So excited to finally be able to share my first paper and the culmination of my PhD work with @felipekteixeira.bsky.social 🪰🔬 www.pnas.org/doi/10.1073/...

Wow, huge congratulations on your ERC Consolidator @leandroquadrana.bsky.social!Truly well-deserved, I’m really happy for you! www.insb.cnrs.fr/fr/personne/...

Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches May 18-22, 2026 Roscoff, France Abstract deadline: January 31, 2026 Apply here: cjm.sb-roscoff.fr/en

JASPAR 2026 is out 🎉 The new release massively expands the TF motif collections and adds a dedicated DeepLearning collection of motifs learned from deep learning models. Database: jaspar.elixir.no Paper (NAR): doi.org/10.1093/nar/... 🧵1/2

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

Membrane #nanotubes are cytoskeletal structures that facilitate intercellular communication. This study shows that polar cell-derived #microtubule nanotubes play a role in #Drosophila #fertilization, creating a channel in the eggshell that facilitates #sperm entry @plosbiology.org 🧪 plos.io/3XwOlvS

Another envelope protein in the human genome. Expressed in the placenta, of course.

And here is the link to access the whole pdf. Enjoy! I strongly believe that focusing on information & computation during Development provides an important framework, that encapsulates the genetic, chemistry & mechanics, but focusses on organisation, dynamics & logic. PDF: tinyurl.com/4hn34t8w

An open webinar on our reproducibility project 'WHAT 400 DROSOPHILA PAPERS Teach Us about Doing Better Science' on December 9th 2PM EEST time (1PM Swiss time). Registration below

Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5

Our lab is actively looking for posdocs and there is NOW an Open Call for Postdoc contracts (3 years) here: www.aei.gob.es/en/announcem...

anybody looking for exciting opportunities in RNA research, with the goal to use and learn state of the art thinking and experimenting: here is a good starting point. Ulrich is an outstanding scientist and natural leader. 👇👇👇👇

Excited to share our new @narjournal.bsky.social paper! Using ReLo and AlphaFold, we described a network of interactions between Drosophila piRNA pathway factors suggesting new links how they coordinate to ensure transposon silencing and genome integrity. academic.oup.com/nar/article/...

Transposon Regulation in the Caenorhabditis elegans Germline and Soma www.biorxiv.org/content/10.1...

Congratulations to Magnus Nordborg of the GMI and @oeaw.bsky.social who, together with Leandro Quadrana and @pierrebaduel.bsky.social, has received an @fwf-at.bsky.social Grant for the project “Genetic and epigenetic determinants of transposon dynamics”. More here: www.oeaw.ac.at/gmi/detail/n...

Our latest pre-print on TE-mediated tandem duplication of the ToxB effector is now online...still a puzzle for us but we think it is in a Helitron! Together with amazing collaborators, Reem Aboukhaddour and Ryan Gourlie #TE #fungi www.biorxiv.org/content/10.1...

piRNA-directed DNA methylation may not be a mammalian invention, but can already be found in the germline of axolotl salamanders Donal O’Carroll and coworkers www.embopress.org/doi/full/10....

TE x ZFP = Evolution! Writing this with Olga @orpsf.bsky.social & Didier @trono-lab.bsky.social was a major highlight of my 🇨🇭sabbatical. Such a treat! 🍫Hope you enjoy it as much as we enjoy piecing it together.

Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

(1/9) Join us in Bern, Switzerland (8–11 Feb 2026) for our EMBO Workshop on Molecular Mechanisms of Selfish Elements and Strategies! Organized with Tanja Schwander, Laura Ross (@laurarossevo.bsky.social) and Axel Imhof. meetings.embo.org/event/26-sel... #EMBOselfishElements #EMBOevents

Some impressions from the rather fabulous #EMBOmobilegenome Mobile Genome meeting in Heidelberg Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, … @events.embl.org The transposon community is going very strong. see you all again in 2027!!

great to be at the #EMBOMobileGenome meeting in Heidelberg with a wonderful bunch of colleagues, speakers and attendees. this meeting is a good reflection of the excitement and collegiality in the transposon field. kindly sponsored by @embo.org

Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner! Congratulations to Vincent and Emilie @igred.fr ! links.springernature.com/f/a/L1ogzL3H...

On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social flies fly! @fly-eds.bsky.social www.cell.com/developmenta...

When transposons jump, genomes diverge - even in cultured cells. I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. 🧬🧵 (1/12)

It is today and tomorrow! #IBENS International Symposium on Epigenetic Inheritance will bring together leading international experts in the field and pay tribute to Vincent Colot and Eric Meyer, two pioneers of epigenetics and eminent colleagues, on the occasion of their retirement.

Love RNA biology? Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇). PhD student/postdoc position co-supervised by Clemens Plaschka & myself. DM or email us if you’d like to know more! @vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social

🌿⚖️ Growth or defense? A new study in Science Advances shows how the PAF1 complex helps plants toggle between growth and immune responses by regulating gene expression. 📖 science.org/doi/10.1126/... 🔬 Collaboration between Wuhan Univesity & @cnrs.fr

Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included. training.institut-curie.org/courses/deve...