ME Torres-Padilla
@metorrespadilla.bsky.social
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https://www.helmholtz-munich.de/en/ies
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ME Torres-Padilla
Goeke Lab
10 days ago
We are thrilled to release Bambu-pipe ๐งฌ ๐ A Nextflow pipeline built for speed, scalability, and precision โ unlocking isoform-level insights from long-read single-cell and spatial RNA-seq data๐ก ๐ GitHub:
github.com/GoekeLab/bambu-pipe
๐ Preprint:
doi.org/10.1101/2024.12.30.630828
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GitHub - GoekeLab/bambu-pipe: Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu
Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu - GoekeLab/bambu-pipe
https://github.com/GoekeLab/bambu-pipe
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Emilio Lecona
9 days ago
Salimos, salimos.
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Visionary Inspirational These are two of the words that come to mind when i think of Pierre, whom I had the privilege to know and work at the Institute he founded. He led a field and he led the people.
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13 days ago
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Alexis Verger ๐งฌ๐งซ๐งช
14 days ago
#RIP
Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor
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Nicolas Rivron
about 1 month ago
Hi all! ๐
leeboratory.bsky.social
and I are recruiting a VIPยณ postdoc to join our teams and decode the genetic logic of how blastoids transit to the post-implantation stage. MolBio, genetics and computational approaches. If this sounds like you (or someone you know), weโd love to hear from you! ๐
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ME Torres-Padilla
IRB Barcelona
about 1 month ago
๐ข We are
#hiring
!
#GroupLeader
positions open at
#IRBBarcelona
in
#ChemicalBiology
and
#StructuralBiology
. Application deadline: May 22, 2026 ๐๐ฟ๐ผ๐๐ฝ ๐๐ฒ๐ฎ๐ฑ๐ฒ๐ฟ ๐ถ๐ป ๐๐ต๐ฒ๐บ๐ถ๐ฐ๐ฎ๐น ๐๐ถ๐ผ๐น๐ผ๐ด๐ โก๏ธ
shorturl.at/1tE3n
๐๐ฟ๐ผ๐๐ฝ ๐๐ฒ๐ฎ๐ฑ๐ฒ๐ฟ ๐ถ๐ป ๐ฆ๐๐ฟ๐๐ฐ๐๐๐ฟ๐ฎ๐น ๐๐ถ๐ผ๐น๐ผ๐ด๐ โก๏ธ
shorturl.at/eKiJn
#IRBJobs
#Jobs
#AcademicSky
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ME Torres-Padilla
The Francis Crick Institute
about 2 months ago
Crick evolutionary biologist
@margaridamcm.bsky.social
is working with conservation charity ZSL to investigate an enduring mystery: how the placenta has evolved with incredible variation across species. Read the full story:
www.crick.ac.uk/news/2026-03...
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ME Torres-Padilla
Epigenetics at Helmholtz Munich
about 2 months ago
DEADLINE EXTENDED: Summer School on Chromatin Biology. Transform your knowledge and skills with this 2 week course focusing on ATAC-seq, ChIP-seq, ChIC/CUT&RUN, CUT&Tag, and bioinformatics analyses. Aug 17 - 29 Interested? Apply by April 18
bit.ly/4bZwHHR
#abcam
#summerschool
#phd
#helmholtzmunich
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Summary - Summer School on Chromatin Biology: A Hands-On Expedition
https://bit.ly/4t3Tbyx
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ME Torres-Padilla
Epigenetics at Helmholtz Munich
about 2 months ago
Time is almost up! Get your application in now for the Chromatin Summer School 2026. โ Summer in Munich โ Immersive lectures โ Hands on training โ Networking with leading scientists in the field including
@metorrespadilla.bsky.social
and
@robertife.bsky.social
Apply before March 29:
bit.ly/4t3Tbyx
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ME Torres-Padilla
The Francis Crick Institute
about 2 months ago
โI think itโs a real mistake to forget where the pipeline for all this begins.โ John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it.
www.crick.ac.uk/news/2026-03...
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The EMBO Journal
about 2 months ago
Which transcription factors control transposable element expression during zygotic genome activation? Gain-of-function screen by
@metorrespadilla.bsky.social
and coworkers identifies TBP as direct regulator of mouse endogenous retrovirus-like elements
link.springer.com/article/10.1...
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TBP regulates transposable element expression in early mouse embryos - The EMBO Journal
The activation of the embryonic genome is a crucial step in development. In addition to thousands of genes, many transposable elements (TEs) are robustly transcribed during early mammalian development...
https://link.springer.com/article/10.1038/s44318-026-00736-w
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ME Torres-Padilla
Epigenetics at Helmholtz Munich
2 months ago
โฐ Deadline approaching! Apply now for the Chromatin Biology Summer School 2024 and join an inspiring week of science, learning, and community. Submit before March 29th to be considered for this exciting opportunity:
bit.ly/4oGDR8f
#chromatin
#summerschool
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Just out! ๐ for TFs that regulate TEs.Clara's work with
@tamas-schauer.bsky.social
@marliesoomen.bsky.social
@palmrinmoy.bsky.social
and bluesky-less lab members ๐ identifies TBP as a regulator of specific ERVL class: MaLRs in ๐ญembryos -as always -feedback welcome๐
link.springer.com/article/10.1...
2 months ago
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Congratulations Melina
[email protected]
!! Very nice to read this news. ๐๐๐๐
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2 months ago
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ME Torres-Padilla
We go live!!! Join us Munich July5-7th to hear exciting research on
#Replication
by leaders in the field AND !! registration is FREE ๐ฅณ (but mandatory) - we hope to see many in Munich ๐บ
@helmholtzmunich.bsky.social
@replifate.bsky.social
@epicrossborders.bsky.social
replifate.eu/event/meetin...
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Events for February 2026
06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding howโฏDNA replication...
https://replifate.eu/event/meeting-on-dna-replication-and-its-impact-on-genome-and-chromatin-maintenance/
3 months ago
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Stefan Luschnig
2 months ago
The CiM-IMPRS PhD program in
#Mรผnster
is offering 16
#PhD
positions in Life and Natural Sciences! Perform cutting-edge resesearch in a vibrant international setting and lively city! Apply by May 1st, 2026 - see
www.uni-muenster.de/CiM-IMPRS/ap...
@uni-muenster.de
@mpi-muenster.bsky.social
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Nadine Vastenhouw
2 months ago
What an opportunity! Donโt miss it!!
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Don't forget to sign up - outstanding speakers, great discussions - join us in Munich in *July* ๐๐๐๐๐๐๐
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2 months ago
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Veronica Finazzi
3 months ago
Happy to share our new preprint! ๐ We benchmarked methods for locus-level transposable element quantification in short-read scRNA-seq, using both real datasets and simulations with read-level ground truth. Huge thanks to
@catavallejos.bsky.social
and
@antonio-scialdone.bsky.social
!
#TEsky
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ME Torres-Padilla
Claudia Keller Valsecchi
3 months ago
Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if youโre passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal ๐ชผ ๐ชฑ ๐ ๐ฆ ๐ฆ ๐ท๏ธ tree of life
www.biozentrum.unibas.ch/open-positio...
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Postdoctoral Researcher (ERC-funded project)
https://www.biozentrum.unibas.ch/open-positions/detail/postdoctoral-researcher-erc-funded-project
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Joaquina Delas
3 months ago
๐ฃ We are looking for new colleagues ๐ฌ๐งฌ๐งช The
@lmcb-ucl.bsky.social
at University College London
@ucllifesciences.bsky.social
are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.
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ME Torres-Padilla
Max Perutz Labs Vienna
3 months ago
Fantastic news! ๐ The Perutz is excited to welcome Danny Nedialkova as a new group leader starting this April! ๐ She will strengthen the institute's research on the fundamental mechanisms that shape cellular physiology and disease โก๏ธ
www.maxperutzlabs.ac.at/research/res...
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ME Torres-Padilla
3 months ago
Find our latest Perspective article in Nature Genetics on "The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements" at
www.nature.com/articles/s41...
, with implications for the future of research on the cause of human disease.
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The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements - Nature Genetics
This Perspective explores the co-evolution of transposable elements and KRAB zinc-finger proteins in relation to their integration into human gene regulatory networks, highlighting their potential eff...
https://www.nature.com/articles/s41588-025-02498-3
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Check this out ! ๐๐work from
@martingroth.bsky.social
& Valentin (bluesky-less) on new findings of DNA methylation &photorespiration - interesting consequences for our environmental 'check' and epigenetic regulation in beautiful plant systems ๐ชด-which continue to teach us a lot as epigeneticists ๐ฑ๐๐ป
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3 months ago
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Guillermina Ramirez-SanJuan
3 months ago
Excited to share our new preprint exploring how Paramecium achieves diverse flow functions, i.e. feeding and swimming, simultaneously. This work was spearheaded by our ExM expert, PhD student Daphne Laan
@daphnelaan.bsky.social
:
www.biorxiv.org/content/10.6...
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Rob Schneider
3 months ago
Fellowship application dealdine for students from low income countries ๐will be in 1๏ธโฃ week. Dont miss out on this opportunity ! Hands on Summer School. Cut&Run, Cut@Tag, ChIP, ATACseq and analyse your own data ! โก๏ธUnique opportunity ! 15 exiting days โ Daily high profile lectures. ๐
bit.ly/4oGDR8f
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ME Torres-Padilla
Sylvie Noordermeer
3 months ago
Science meets art! Our first artistic experience as a lab working together with amazing artist Pei-Ying Lin. Very much looking forward to the final exhibition in Munich early July.
@replifate.bsky.social
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ME Torres-Padilla
EpiCrossBorders
3 months ago
Exchange update! In 2025, EpiCrossBorders PhD Daniele Scarcella joined a research exchange in Edinburgh, advancing his work on lineage bias in hematopoiesis. โInformal scientific exchanges really accelerated my thinking.โ ๐Find out more:
bit.ly/3Mr1wfV
#Epigenetics
#PhD
#Scientificexchange
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Lena Kutscher
3 months ago
We hope our data can be useful to you, and to increase its usability, we've generated an exploratory web app as a resource and starting point to examine our data on the
@kaessmannlab.bsky.social
website
apps.kaessmannlab.org/HindbrainExp...
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Hindbrain Explorer: A multi-omics atlas of human hindbrain development.
This app accompanies the paper: A multi-omics atlas of human hindbrain development. This interactive application allows users to explore the data presented in the study and use the machine learning mo...
https://apps.kaessmannlab.org/HindbrainExplorer
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Particularly excited to announce "In Formation" ๐Vernissage 17h00 Munich *5th of July* @Muffatwerk 1st exhibition of Art&Science work from 4 artists, including
annadumitriu.co.uk
+
@replifate.bsky.social
Helen Pynor,Solveig Lill & Pei-Ying Lin
replifate.eu/event/in-for...
๐STAY TUNED 4more info
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Events for February 2026
We are thrilled to announce In Formation, the first exhibition featuring work from four artist-in-residence projects that bring art into the heart of scientific stem cell and epigenetics research. ...
https://replifate.eu/event/in-formation-the-first-exhibition-featuring-work-from-four-artist-in-residence-projects/
3 months ago
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ME Torres-Padilla
Sara Wickstrom
3 months ago
Excited to share our work on epithelial multilayering - identifying why stem cell stay in the basal layer and how and why differentiating cells move up. Great collab with
@manningresearch.bsky.social
and Niessen labs! Check out preprint and great summary below
www.biorxiv.org/content/10.6...
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ME Torres-Padilla
EMBL-EBI
3 months ago
Weโre hiring: Research Group Leader in computational biology. Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI. Apply by 11 April 2026:
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ScienceCareers
@ewaldlab.org
@embl.org
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We go live!!! Join us Munich July5-7th to hear exciting research on
#Replication
by leaders in the field AND !! registration is FREE ๐ฅณ (but mandatory) - we hope to see many in Munich ๐บ
@helmholtzmunich.bsky.social
@replifate.bsky.social
@epicrossborders.bsky.social
replifate.eu/event/meetin...
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Events for February 2026
06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding howโฏDNA replication...
https://replifate.eu/event/meeting-on-dna-replication-and-its-impact-on-genome-and-chromatin-maintenance/
3 months ago
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ME Torres-Padilla
EvolDir
3 months ago
Aarhus University is seeking a Tenure-Track Assistant/Associate Professor in Bioinformatics/Coโฆ
https://nat.au.dk/en/about-the-faculty/vacant-positions-and-career/job/tenure-track-assistant-professor-associate-professor-in-bioinformatics-and-or-computational-biology-at-aarhus-university-denmark
#job
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Tenure-Track Assistant Professor / Associate Professor in Bioinformatics and/or Computational Biology at Aarhus University, Denmark - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University
https://nat.au.dk/en/about-the-faculty/vacant-positions-and-career/job/tenure-track-assistant-professor-associate-professor-in-bioinformatics-and-or-computational-biology-at-aarhus-university-denmark
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Helmholtz Munich
4 months ago
The Epigenetics Community at
#HelmholtzMunich
, together with
#Abcam
, is hosting the 3rd
#Chromatin
#SummerSchool
in Munich: ๐ 17โ29 August 2026 โฐ Apply by March 29, 2026 ๐ Applications & info:
bit.ly/4oGDR8f
@epihmgu.bsky.social
@metorrespadilla.bsky.social
@robertife.bsky.social
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Alejo Rodriguez-Fraticelli
4 months ago
๐จWE'RE RECRUITING AT
@irbbarcelona.org
!!!! --- ADVANCED GENOMICS FACILITY MANAGER --- An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!! APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
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Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona
IRB Barcelona invites applications for the position of Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the Director, Technology Strateg...
https://recruitment.irbbarcelona.org/jobs/7124180-head-advanced-genomics-technologies-core-facility-ref-cf-26-01
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Francesca Mattiroli
4 months ago
Donโt miss the 2026 Hubrecht symposium. Submit your abstract before February 1st. Stellar speakers:
@pauligroup.bsky.social
@gerlichlab.bsky.social
Petra Hajkova
@tinekelenstra.bsky.social
@foijer-lab.bsky.social
Joost Gribnau, Melissa Rinaldin
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Institut Pasteur | 130 years of biomedical research
5 months ago
๐ฌ Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies ๐ Deadline: Feb 9, 2026 ๐ฅ 2-12 years post-PhD Apply now ๐
research.pasteur.fr/en/call/crea...
#JobOpportunity
#Research
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Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
https://research.pasteur.fr/en/call/creation-of-new-junior-research-groups-at-the-institut-pasteur-call-for-applications-2026/
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The Groth lab
4 months ago
You can read more about Anja's award here:
novonordiskfonden.dk/en/news/biom...
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Biomedicine prize awarded to Professor Anja Groth for groundbreaking discoveries in epigenetic cell memory - Novo Nordisk Fonden
https://novonordiskfonden.dk/en/news/biomedicine-prize-awarded-to-professor-anja-groth-for-groundbreaking-discoveries-in-epigenetic-cell-memory/
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ME Torres-Padilla
Helmholtz Munich
4 months ago
How Do Metabolic Changes Influence Our Genes? ๐งฌ Researchers at
#HelmholtzMunich
have discovered new mechanisms by which metabolism impacts our genes through epigenetic regulation. ๐Original publication:
t1p.de/uh7j8
@epihmgu.bsky.social
@robertife.bsky.social
#Epigenetics
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Agristok
4 months ago
Research Manager Job for Plant Growth Facilities and Microscopy at University of Basel,ย Switzerland The University of Basel is recruiting a Research Manager to oversee plant growth facilities and microscopy for the Plant Ecology and Evolution research group. A long-term role combining plantโฆ
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Research Manager Job for Plant Growth Facilities and Microscopy at University of Basel,ย Switzerland
The University of Basel is recruiting a Research Manager to oversee plant growth facilities and microscopy for the Plant Ecology and Evolution research group. A long-term role combining plant cultivation, imaging, and research support.
https://agristok.net/2026/01/11/research-manager-plant-growth-facilities-microscopy-university-of-basel/
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Capucine Van Rechem
4 months ago
Registrations are opened! Come join us in Dublin in June!
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Genes & Development
5 months ago
Wrapping up G&D 2025 on a high note!!! Stay tuned for another great year of exciting research. HAPPY NEW YEAR!!!
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Kerstin Gรถpfrich
5 months ago
Still time to apply until January, 19th!
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Antonio Scialdone
5 months ago
Our new preprint is out:
www.biorxiv.org/content/10.6...
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs. A reminder of why bias-aware evaluation matters!
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Hidden sampling biases inflate performance in gene regulatory network inference
Accurate reconstruction of gene regulatory networks (GRNs) from single-cell transcriptomic data remains a major methodological challenge. Recent machine learning approaches, particularly graph neural ...
https://www.biorxiv.org/content/10.64898/2025.12.19.695616v1
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EpiCrossBorders
5 months ago
๐ Wrapping up 2025 with EpiCrossBorders! A year of breakthroughs, cross-border exchanges, multiple publications & vibrant outreach. Next stop: 2026 Symposium in Edinburgh + new workshops & theses submissions Thank you to all who made this possible. ๐
#Epigenetics
#PhDprogram
#Sciencecollaboration
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Rob Schneider
5 months ago
Excited to share new manuscript on histone acylations, exploring how H4K16 acylations regulate inter and intranucleosomal interactions and how they confer resilience to metabolic challenges in vivo. Thanks to all authors +1 author
@sandrani.bsky.social
Enjoy ๐๐
www.sciencedirect.com/science/arti...
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H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations
Histone modifications play crucial roles in genome function. However, how chromatin integrates physiological and metabolic responses at the molecular โฆ
https://www.sciencedirect.com/science/article/pii/S1097276525009712
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Brian Plosky
5 months ago
Donโt miss this opportunity! Please share with recent PhD grads or students who will soon graduate
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Rob Klose
5 months ago
An early Christmas present for those interested in chromatin and transcription! Fantastic work from
@au-ho-yu.bsky.social
and
@aleksszczurek.bsky.social
. Thanks to Inge and Michiel for their help. Please repost!
www.biorxiv.org/content/10.6...
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SET1/MLL complexes control transcription independently of H3K4me3
Histone H3 lysine 4 trimethylation (H3K4me3) at gene promoters is thought to play a central role in gene transcription. H3K4 methylation is deposited by the SET1 (A/B) and MLL (1-4) multi-protein comp...
https://www.biorxiv.org/content/10.64898/2025.12.08.692985v1
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Rob Schneider
5 months ago
Please RT ๐ง Registration open for โก๏ธ"Summer School on Chromatin Biology" Our 2 weeks hands on expedition ๐งช๐ฉโ๐ปAugust 2026. 3. edition. Learn CUT@Tag, CUT@Run, ChIPseq, ATACseq AND to analyse your own data at
@helmholtzmunich.bsky.social
Daily letures by experts in the field ! โถ๏ธ
shorturl.at/jrA8i
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