I didn’t get to meet the legend of Garcia Bellido as a PhD student at the “Severo Ochoa” as he was already half retiring… but even then, his presence in the department was all encompassing… My condolences to the family of scientists that he mentored. What a giant - we’ll always be in his debt.

Can't help but sharing this thought on #Genetics from A. Garcia Bellido (1936-2025). His legacy runs deep through the work of his disciples and readers but it is there.

Calling cancer data scientists! 📊 💽 🧮 We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...

A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording - @jshendure.bsky.social @troymcdiarmid.bsky.social @uwgenome.bsky.social go.nature.com/49eTPCu

Demain mercredi 12 nov. 17h30, leçon #2 de #EmmanuellePassegue @columbiauniversity.bsky.social , Prof. Invitée @college-de-france.fr sur les cellules souches hématopoïétiques🩸 ‘Environmental crosstalk and niche regulation’ 🧫. Free access, no registration.

Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org 🤩. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing👇

Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues journals.biologists.com/dev/issue/15...

Brilliant development!!!

So cool embryonic pancreas epithelium modeling using stem cells by the Wells lab! #PancSky www.biorxiv.org/content/10.1...

I am starting to believe that for every major advancement in cancer therapeutics (especially new modalities) we should always run a small ph2b arm with the new therapy being applied ahead of the SoC, and not always after. Obv not easy for rare cancers… but otherwise what’s the bottleneck?

🧬 Excited to share Nicheformer out now in Nature Methods! A transformer foundation model linking single-cell & spatial omics, learning spatial context from gene expression to map tissue organization. Led by Ale Tejada & Anna Schaar 👏 👉 www.nature.com/articles/s41...

🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️ aacrjournals.org/cancerdiscov...

Our recent Cancer Discovery study (Centonze et al.) shows that within hours, metastatic CRC cells switch from an EMP1⁺ invasive state to an LGR5⁺ stem-like program, highlighting that Plasticity is a dynamic, regulated cell-state decision #Bluetorial below👇🏼 #KRAS #Plasticity #ColorectalCancer

Beautiful, insightful study from Boezio et al. One of the best clonal analyses I’ve seen so far. We’ll dig in this week! Check it out!

That merely being “under review” by a Nature family journal is offered as a quality proxy for a paper is a tragic illustration of the extent to which academia is addicted to brands and outsources evaluation

The CRG PhD call is now open. Exciting opportunities across diverse topics and within a world-class scientific environment. Our group is offering one PhD position to study chromatin evolution. Consider applying or share with anyone who might be interested! www.crg.eu/en/content/t...

We are hiring!

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

We are happy to share our latest work in @nature.com . We study the genomic and cellular basis of facultative symbiosis in Oculina patagonica - a Mediterranean coral remarkable for its ability to survive long periods without algal symbionts. Led by Shani Levy and @xgrau.bsky.social rdcu.be/eLbaZ

This meeting will be a significant event for those advancing research in stem cell-based embryo models. Submit your abstract and scholarship application by Oct 21! www.keystonesymposia.org/conferences/...

We have two fantastically well-funded #PhD studentships available through the @evomg-dn.bsky.social #EU doctoral network (led by brilliant @mirimiam.bsky.social, @crg.eu). These enable students to move to the UK and come and work with us @icr.ac.uk to exploit #cancer #evolution for patient benefit.

Looking forward to a day at EMBL Barcelona for Science by the Beach Seminar at noon Science by the beach | EMBL.org share.google/Eb8dktOiuUbJ...

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

🚀 WE ARE HIRING 3️⃣ Independent Group Leaders for #mdcBerlin's new cutting-edge Bioengineering Cluster within our Biomedical Engineering Program. Lead cutting-edge research at the interface of biology, engineering, and medicine in Berlin. 👉 Apply now: www.mdc-berlin.de/career/jobs/...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

🚨 New paper alert! Sex and smoking bias in the selection of somatic mutations in human bladder www.nature.com/articles/s41... by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...

🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk. ✍️ #IRBBarcelona & University of Washington ➡️ bit.ly/42wcIN5 📌 DOI: 10.1038/s41586-025-09521-x #IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social 🧵👇

Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...

🚀 As first official act, we are hiring! 🎓 We’re looking for a PhD student to work at the interface of computational biophysics, machine learning & human mutations. 📌 FPI fellowship, 4 years fully funded! More information here: www.bsc.es/join-us/job-...

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back. I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support

👀👀👀

🚨JOB ALERT🚨 FRIENDS PLEASE SPREAD and RT We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇

Today is a special day, some would call it the first of the rest of my life. I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me. #NotInTheGenes #CellsRUs

Surprising finding that standard chemo renders AML resistant to subsequent treatment with menin inhibitors. Published in @isehsociety.bsky.social journal Exp. Hem.: www.exphem.org/article/S030...

O M G

Julio just saved us all many days of research for the next grant application. I wish some Bluskey posts had DOIs. This would definitely be most cited.

EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026. Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open - w.molgen.mpg.de/embryo2026

"Head down focus on the science" folks: here is one super easy thing you can do today.

We have space for two postdoctoral fellows in the Taipale Lab at the @sangerinstitute.bsky.social. This is a core-funded open position! Come with your ideas and interests and we can develop a project together. sanger.wd103.myworkdayjobs.com/en-US/Wellco...

🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳 📖 Preprint: www.biorxiv.org/content/10.1... 🔍 Explorer: explore.omnipathdb.org OmniPath integrates 160+ resources for multi-omics analysis & modeling. 🧶⬇️

Asking BlueSky for help: For a review, I am trying to accurately credit the first paper that measured pairwise 3D distances between 2 pieces of DNA on the same chromosome (or cosmid). Is Trask 1989 the first? I know of earlier single-locus papers (1982). www.sciencedirect.com/science/arti...

Mechanosensitive and Reversible Chromatin-Lamina Dewetting Triggers Cellular Contraction During Wound Healing https://www.biorxiv.org/content/10.1101/2025.09.10.674927v1

This is an really amazing opportunity. If you get it, you can essentially pick you institute. The package really is rather competitive.

🚨 We’re recruiting PhD students! 🚨 Join the Stem Cell Biology and Evolution lab at @lsiexeter.bsky.social to study planarians, stem cells & evolution. 2 projects available - 1 week left to apply! Interested and no PhD yet? Apply now. Or help us spread the word! 🙌 www.exeter.ac.uk/research/ins...

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

EMBO meeting on "Molecular and Developmental Biology of Drosophila" 21 – 27 June 2026 Registration is now open! Deadline next November 3rd! meetings.embo.org/event/26-dro...

We are pleased to welcome back former Hubrecht director and group leader @hansclevers.bsky.social to the Hubrecht Institute as of today! He will lead the Organoid group – now Clevers group – in the role of distinguished group leader. Read more on our website 👉 www.hubrecht.eu/clevers-retu...

Super excited that our latest work is out! We use optogenetics to dynamically control and study the formation of morphogen gradients. If you are interested in optogenetic tools and/or how cells shape and process extracellular signals, check out @jamesbriscoe.bsky.social's thread and the paper.

Very cool paper!!! Opto-patterning of neural progenitors!