Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then! www.science.org/doi/10.1126/...

Outstanding PhD fellowship call OPEN for excellent students. lacaixafoundation.org/en/doctoral-... This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels). If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!

popEVE is out in Nature Genetics! 🎉 We built a proteome-wide model that combines cross-species and human population variation to rank missense variants by disease severity and help diagnose rare genetic disorders. rdcu.be/eRu7K

Happy to see Atsuhiro Taguchi's work on genes involved in liver zonation published in Dev @cellpress.bsky.social. Kudos to all authors at @molgen.mpg.de #MeissnerLab #HniszLab. Grateful for the opportunity to help! www.sciencedirect.com/science/arti...

check out my journal club on the seminal discovery of local translation in neurons (Kang & Schuman. 1996), and more recently, its activity in neocortex neurodevelopment (Pilaz...Silver. 2023). cheers to the @erin-schuman.bsky.social & @debbysilver.bsky.social labs! www.nature.com/articles/s41...

Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social. www.cell.com/cell-reports... Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12

"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes". A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read. doi.org/10.1016/j.cd...

@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos www.biorxiv.org/content/10.1... They find novel mechanisms involving and interplay of proliferation and mechanical constraining. #NotInTheGenes #CellsRUs

Really excited to present the results of a fantastic collaboration with Jesse Veenvliet @jesseveenvliet.bsky.social @mpi-cbg.de @poldresden.bsky.social 🤩 We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species ➡️ www.biorxiv.org/content/10.1...

Oh wow - pre-made templates :) - EB I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org

Wouldn’t it be cool to leverage the throughput of single-cell data to study splicing regulation even when we lack exon resolution? 😀 Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...

Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏 www.crick.ac.uk/careers-stud...

Two positions available (start Jan/Feb 2026): - Research Assistant: surl.li/atndnv - Master Student: surl.li/kgwrni Deadline: Nov 1st Please reach out to me ([email protected]) if you want to join us in sunny Barcelona!☀️

🚨JOB ALERT🚨 FRIENDS PLEASE SPREAD and RT We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇

yo scientists awesome opportunity! ⬇️🔥

I think everybody knows but Adri is awesome!

🚨JOB ALERT🚨 FRIENDS PLEASE SPREAD and RT We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇

Stay Connected with VGZT Season 7 🌍 From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.

THANK YOU for many years of friendship, support and for sharing your great Science La Pedrera #Barcelona #NotInTheGenes #CellsRUs #Cambridge

Last days to apply! Cool project, cool cities! :-) (Please repost! 🙏)

With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs

Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social We will use medaka to study how organs can be reprogrammed! Details on how to apply below 👇 #JobOffer #ScienceJobs #EvoDevo #GeneRegulation

Ever wondered how to get a gastruloid to grow a head? The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....

🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social 📩 Questions? Contact us ✉️ 🔗 Apply here: www.mpg.de/25243280/bio...

🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...

I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role: www.fmi.ch/education-ca...

🧬 Els oòcits humans “s’apaguen” per protegir-se ➡️Un estudi del #CRGenomica revela que els òvuls humans redueixen l’activitat dels sistemes de neteja quan maduren.  Aquesta aturada parcial podria ser la clau per mantenir-se vius i sans.  ℹ️T'ho expliquem:

📣 New preprint! We present SpinePy, a modular framework that enables automated 3D spatiotemporal quantification of #gastruloids & other multicellular in vitro systems. Spearheaded by @cryaaa.bsky.social @mpi-cbg.de. Check out his thread 👇 & the paper: www.biorxiv.org/content/10.1...

Understanding how embryos build themselves requires studying developmental trajectories. This is beautiful work from @santoslab.bsky.social!

Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria www.biorxiv.org/cgi/content/...

I am deeply honoured to have been recognized by the European Research Council with a #StartingGrant. @erc.europa.eu With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.

Thrilled to share that our group will be supported by an ERC Starting Grant! 🚀 With the project 'DECIPHER', we will decode and perturb gene regulation to engineer human cell subtypes, niches, and maturation. We’ll soon be recruiting at all levels — stay tuned for opportunities to join us!

Congratulations to Aydan Bulut-Karslıoğlu on receiving the GSCN Young Investigator Award 2025! The award recognizes her lab’s research on dormancy. Read more: www.molgen.mpg.de/news-2025-gs... @bulutkarslioglu.bsky.social

I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 🎉 We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.

ISSUE 16 Review on metabolic diversity of plants Resource: mouse organ-/age-specific proteome profiles Cardiolipin inhibition of non-canonical inflammasomes Optochemical profiling of NMDA receptor diversity Cover: @gzaffagnini.bsky.social et al @bokelab.bsky.social www.embopress.org/toc/14602075...

Honored to receive the @isrbio.bsky.social Rising Star Award for our work in regeneration biology! Grateful to the committee and our colleagues for the recognition. A huge motivation for the lab. Excited to give the award talk in Madison next week and connect with everyone! 😎🥳🍾 shorturl.at/LnkSt

Here we go again! Our paper on #proteostasis in human oocytes appeared on the latest @embojournal.org cover! A great collaboration with Dexeus Mujer @bokelab.bsky.social ! 🥂👏🏻💪🏻

1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells". www.cell.com/cell-stem-ce...

Very happy to share the peer-reviewed version of our work on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4, published in @natsmb.nature.com! rdcu.be/ezGqT Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu

📢 Our August issue is online! 🎨 The cover highlights a Feature Review from Stephanie Rosswag de Souza, @gzaffagnini.bsky.social, and @bokelab.bsky.social on how proteostasis functions in cellular dormancy across a number of examples, from yeast to adult quiescent stem cells and vertebrate oocytes.

We’re so happy that our review on “Proteostasis in cellular dormancy” was chosen for the cover of the August issue of @cp-trendsbiochem.bsky.social in the old-school way; we were invited! Many thanks to our editor, Sannie Culbertson, and the reviewers for a great experience - EB

🧬🧬🧬 New review from the lab: Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks authors.elsevier.com/sd/article/S... By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.

How can we identify novel regulators of germ layer differentiation and body patterning? I am happy to announce that my preprint using single-cell CRISPR screens in gastruloids to answer this question is now online! Thank you to the rest of the @sendoellab.bsky.social and all coauthors!

💫The July issue of @natgenet.nature.com is out! Featuring: ✅retrotransposons in limb malformation and cancer ✅single-cell Micro-C ✅long-term effects of chemotherapy on normal blood cells ✅blood regulatory variation map in South Africans And more! ⬇️ www.nature.com/ng/volumes/5...

🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇

Excited to share our latest work with @jamesbriscoe.bsky.social . A global #cis-regulatory temporal program guides how spatial cues are interpreted in neural progenitors. We show how #space and #time can be integrated to generate cell type diversity in the #spinalcord. Congrats to all authors.

Pleased to share my new review: Ovulation: A cellular symphony in three movements 💥🥚 Ovulation is more than egg release—it's a tightly regulated, tissue-scale process. Here, I present a temporal framework structured as a symphony performed by the cells of the follicle. 🔗 doi.org/10.1016/j.se...

Excellent work indeed, but I feel in this context @adrianobolondi.bsky.social fantastic work should also be mentioned www.cell.com/developmenta...

Two new preprints from the @arjunraj.bsky.social‬ on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about biorxiv.org/content/earl... biorxiv.org/content/earl...