Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...

Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩

New Preprint alert!🚨 Super excited to share my postdoc work now on BioRxiv. How does PRC2 loss lead to developmental failures? We combined rapid protein degradation with TLS embryoid models to uncover temporal and lineage-specific dependencies 🧬. Preprint: doi.org/10.64898/2026.04.18.719361

A new study shows how different regulatory genetic elements control when a key developmental gene is active in the body. The findings could explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown.

In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv. www.fmi.ch/news-events/...

📣 New Perspective out in @natcellbio.nature.com! With an interdisciplinary team of scientists, ethicists & lawyer we propose embedded ethics as a framework for navigating the complex ethics of human stem cell–based embryo models. www.nature.com/articles/s41... Free full text link: rdcu.be/fckmY 🧵

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

Honored to receive a La Caixa Junior Leader Fellowship @caixaresearch.bsky.social at @crg.eu. This recognition will support our research on oocyte dormancy and proteostasis for the next three years🥚! Big thanks to previous funders @embo.org & MSCA @ec.europa.eu and to @bokelab.bsky.social @prbb.org!

Many regulatory layers modulate splicing factors at the same time impacting their activity. How can we quantify it? Apparently "functional" target exons give us a hint and uncover two cancer programs. Have a look at our solution: www.nature.com/articles/s41...

🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...

🎉 Very happy, stoked & honored to have been awarded an @hfspo.bsky.social Research Program Grant for a dream project conceived w/ Eric Glowacki @ceitec.eu & @bernasozen.bsky.social 🥳 Thanks @hfspo.bsky.social for funding bold ideas & projects that aim to push across boundaries 🙏 #stuffthatmatters

🚨JOB ALERT🚨PLEASE SPREAD and RT Searching for a motivated Master’s student @bokelab.bsky.social @crg.eu @prbb.org to investigate how proteostasis in oocytes influences dormancy and fertility. Reach out to me ([email protected]) to join us in sunny Barcelona! See details below👇

Tomorrow will be the last day to apply! Send your applications to join us!

🧠 There’s still time to register👇 and join the YPI community for a full day of neuroscience, skills, trainings, strategies, discussions, networking and resilience building - by the beach 🏖️! @fens.org satellite event! youngpisymposium2026.com

Thrilled to receive the 2026 Boehringer Ingelheim FENS Research Award. Exciting to see our work on brain development recognized by the European neuroscience community. Grateful to my mentors, my lab, and my family. Award lecture at FENS Forum Barcelona in July! www.fens.org/news-activit...

12 days left to apply! @bokelab.bsky.social @crg.eu @prbb.org See here: recruitment.crg.eu/content/jobs...

With the human embryo model field rapidly expanding, it would be good if those venturing into it properly acknowledge the history of the field and give credit where credit's due. I doubt hTLS would be there w/o mouse gastruloids @amartinezarias.bsky.social @susannevandenbrink.bsky.social & TLS.

This is now the 2nd human trunk-like-structure (TLS) paper in a row that fails to cite our work @adrianobolondi.bsky.social, which demonstrated the first TLS (mouse). Especially striking since the preprint studies (a.o.) the TBX6-KO phenotype, which we used as a proof-of-concept in mouse TLS (1/2)

Happy 🥲 We're now looking for a postdoc and a technician to work on this super exciting 5 years project on mRNA mtabolism and poly(A) tail length control. Links to apply here: Postdoc: careers.humantechnopole.it/job/Postdoc-... Technician: careers.humantechnopole.it/job/Technici...

Three more weeks to apply and join us in Barcelona! Help us understanding how oocytes regulate proteostasis and fertility! Find here more detailed information on the call: recruitment.crg.eu/content/jobs... Please spread around your communities!

Today we present another of our amazing speakers: @anne-schreiter.bsky.social the executive director from @gso-forresearchers.bsky.social. She will give us an interactive workshop about Leadership and Team-building. Register to our @fens.org Satellite 👉 youngpisymposium2026.com

🚨 Job Alert - Please share! 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! We’re recruiting: ✅ PhD students ✅ Postdocs 💻🧪 Experimental or computational backgrounds welcome 👇 Details below

🚨JOB ALERT🚨PLEASE SPREAD and RT Searching for a motivated Master’s student @bokelab.bsky.social @crg.eu @prbb.org to investigate how proteostasis in oocytes influences dormancy and fertility. Reach out to me ([email protected]) to join us in sunny Barcelona! See details below👇

The ISSCR is pleased to announce that Alexander Meissner, Director of Max Planck Institute for Molecular Genetics, Germany, has been named the recipient of the 2026 ISSCR Momentum Award, supported by BlueRock Therapeutics! Learn more: https://ow.ly/eUNt50YoFm3

Deadline extended until end of March! Join our @fens.org Satellite 👉 youngpisymposium2026.com

Interested in doing a PhD in tumor mechanobiology? At Université Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab. If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!

We wrote a piece on how easy it is to write gene regulatory sequences. - Turns out, it isn't that easy even though we know a lot about cis-regulation. huge credit to @carldeboer.bsky.social to seeing this through so our thoughts aren't lost. I promise, it's a worthwhile read!

INTERESTED IN SINGLE-CELL LINEAGE TRACING? Check our new review @naturerevgenet.bsky.social from the @alejofraticelli.bsky.social lab 🎉🎉 nature.com/articles/s41... With Victoria Parreno, we tried to update the modern manual for genetic tracing and clonal analysis. Read link: rdcu.be/e50gy

Thanks to everyone who joined us at the 2nd Meeting on Early Embryogenesis & Epigenetics last week—great talks and valuable discussions across the community! Huge thanks to our partners at the Weizmann, the speakers, session chairs, and all the behind-the-scenes helpers! www.molgen.mpg.de/embryo2026

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

@tjryan.bsky.social will join the @fens.org satellite @young-pi-neuro26.bsky.social as a keynote speaker. He is Professor of Neuroscience at @tcddublin.bsky.social and Chair of the FENS Advocacy Committee. He will speak about advocacy for neuroscience in Europe. Join us 👉 youngpisymposium2026.com

🚨 Happy to see that my PhD work is finally published! We present METALoci, a tool that integrates #3Dgenome and #Epigenetics to identify regulatory hubs. Applied to #sexdetermination we uncover: ✔️ Non-coding regulatory region controlling Fgf9 ✔️ Meis genes as key players 👉 rdcu.be/e5sm2

🤩💪 Out now! 3D regulatory hubs in sex determination With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social 1️⃣ METALoci – explore #3DGenome 🧬 2️⃣ Non-coding region controlling Fgf9 🧩 3️⃣ Meis genes = new key players 🌟 👉 rdcu.be/e5sm2 1/n Bluetorial 👇

🚨Last week to register!! Noelia Antón Bolaños is one of our amazing keynote speakers. She will tell us all about her journey from Spain to Boston, and starting her lab at @umcutrecht.bsky.social 🛫🌎🛬. Join our @fens.org Satellite event in Barcelona!

yo 🦋 NEURO SKY 📣 the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists! youngpisymposium2026.com

📢Are you a young PI or senior postdoc in neuroscience looking to embark on the challenging journey of starting your own lab? 📆Then save July 5, 2026 in your calendar and join us in Barcelona for the second Young PI Symposium. youngpisymposium2026.com

🧬 We are excited to announce the INTERNATIONAL DUTCH EMBRYO MODEL MEETING 2026 — Engineering the Origins of Life 📅 7–8 May 2026 📍 Utrecht, The Netherlands Register & submit abstracts: www.oncodeinstitute.nl/internationa...

Once your 3D sample is reconstructed, you can rotate, take virtual sections in any orientation, project gene expression through depth, link 3D space with UMAP, and compute spatial differential expression on the reconstructed volume to find region-enriched genes.

To turn spatial data into a 3D object, check our protocol (open source, napari plug-in). @guignardlab.bsky.social @adrianobolondi.bsky.social @ibdm.bsky.social For example, if you have spatial RNA-seq as sections, you can align them automatically to analyse directly in 3D. bio-protocol.org/e5607

We're recruiting a #devbio Postdoctoral Fellow to explore the hTLS system! If you know any fab PhD students finishing, or candidates wanting to get their hands on #SCBEM embryo models, do get them to apply! 🌟https://www.crick.ac.uk/careers-study/vacancies/2026-02-03-postdoctoral-fellow-moris-lab

EMBL scientists Jamie Hackett and Robert Prevedel have been awarded ERC Proof of Concept grants to support the translation of innovative ideas into tangible therapeutic and imaging tools. www.embl.org/news/awards-... @erc.europa.eu @jamiehackett.bsky.social

We wrote a protocol article detailing induction of dormancy in stem cells, embryos, and blastoids. We hope that it is useful to the community. As usual fun to work with @nicolasrivron.bsky.social, Heidar and Dhanur.

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then! www.science.org/doi/10.1126/...

Outstanding PhD fellowship call OPEN for excellent students. lacaixafoundation.org/en/doctoral-... This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels). If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!

popEVE is out in Nature Genetics! 🎉 We built a proteome-wide model that combines cross-species and human population variation to rank missense variants by disease severity and help diagnose rare genetic disorders. rdcu.be/eRu7K

Happy to see Atsuhiro Taguchi's work on genes involved in liver zonation published in Dev @cellpress.bsky.social. Kudos to all authors at @molgen.mpg.de #MeissnerLab #HniszLab. Grateful for the opportunity to help! www.sciencedirect.com/science/arti...

check out my journal club on the seminal discovery of local translation in neurons (Kang & Schuman. 1996), and more recently, its activity in neocortex neurodevelopment (Pilaz...Silver. 2023). cheers to the @erin-schuman.bsky.social & @debbysilver.bsky.social labs! www.nature.com/articles/s41...

Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social. www.cell.com/cell-reports... Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12