(@caixaresearch.bsky.social)

🧠 🧬 A new study led by a researcher in our network, Ángel Barco, reveals how two "epigenetic guardians" — KDM1A and KDM5C — work together to preserve neuronal identity and brain function. ✍️ The findings have been published in @cp-cellreports.bsky.social. 🔗 tinyurl.com/5bh7nrxv

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Cooperative control of neuron-specific repressive chromatin states by intellectual-disability-linked KDM1A and KDM5C demethylases. - Instituto de Neurociencias de Alicante Researchers discover how the interaction of two “epigenetic guardians” protects neuronal identity • This study shows that the enzymes KDM1A and KDM5C collaborate to prevent neurons from activating inappropriate genes, ensuring their proper function. • The findings, published in Cell Reports, open new avenues to understand the origin of neurological disorders associated with mutations in [...] https://tinyurl.com/5bh7nrxv