Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

📢 Institut Jacques Monod Seminars 📅 Oct. 7th 📍 Institut Jacques Monod Invited by the @stemdevevo.bsky.social Lab , @canaztekin.bsky.social will present an Institut Jacques Monod seminar on the theme « Signaling centers of appendage regeneration: from single cells to species » ➡️ buff.ly/Nvw4YZn

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

George, our very first postdoc (super brave!), has been central to so many projects. Had a hugely risky project that paved the way for his regeneration work. Proud to share it here again #PostdocAppreciationWeek 🐸 vs 🐭 👇 🔗 www.biorxiv.org/content/10.1...

Thrilled to share that our Group Leader Prof. Azim Surani, together with Prof. Davor Solter, has been awarded the 2026 Paul Ehrlich & Ludwig Darmstaedter Prize 🎉 for discovering genomic imprinting—a breakthrough that reshaped genetics and launched modern epigenetics.

Out today. 🙏 again to everyone for this wonderful piece of work, in particular to Aurelie @aurhin.bsky.social Chase @chasebolt.bsky.social and Brent @homeobox.bsky.social. 🙏 also to the Harris lab @fish4walking.bsky.social and @neilshubin.bsky.social @biology-unige.bsky.social @college-de-france.fr

🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social 📩 Questions? Contact us ✉️ 🔗 Apply here: www.mpg.de/25243280/bio...

Excited to share our Review on human PGC development covering the latest in vivo observations & in vitro developments, esp. in the last 5 years. Have a read! journals.biologists.com/dev/article/... From: @astar-gis.bsky.social @ki.se Warwick University, @gurdoninstitute.bsky.social

Excited and very grateful to announce that I have been awarded an ERC Starting Grant by @erc.europa.eu! 🎉 This is a fantastic opportunity to further build my team at the Max Planck Institute of Immunobiology and Epigenetics (@mpi-ie.bsky.social) exploring new grounds in fundamental research:

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development. We will have positions available next year. Stay tuned!

🥳 Thrilled to share that our lab has been awarded an ERC StGrant for our project SigReg: Signal to Regeneration! How can we unlock limb regeneration in adult mammals? It’s time to apply what we learned from 🐸 ➡️ 🐭 Thank you @erc.europa.eu for supporting ambitious science!!!

If you want to feel like you know nothing about biology, read this paper. 😭 I want to get it. But brain not cooperating.

Thrilled to share 🎉 I’m starting my lab at University of Zurich, DMLS as Assistant Professor (tenure track) from Jan 2026! The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...

Announcing this year's Life Time Achievement Award. The one and only amazing Professor Brigette Galliot. Our inspiration with both her research and her service.

We are excited to highlight our Rising Star Awardee, Dr. Can Aztekin @canaztekin.bsky.social whose work highlighting the importance of oxygen in regulating regeneration is inspiring. #Onetowatch

Very proud of our @canaztekin.bsky.social on his Rising Star Award 2025 from @isrbio.bsky.social! Find out more about his work on the structural limb #regeneration, specifically in understanding the differences in regeneration abilities across various species: s.gwdg.de/QidoUL #biology #maxplanck

1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells". www.cell.com/cell-stem-ce...

Honored to receive the @isrbio.bsky.social Rising Star Award for our work in regeneration biology! Grateful to the committee and our colleagues for the recognition. A huge motivation for the lab. Excited to give the award talk in Madison next week and connect with everyone! 😎🥳🍾 shorturl.at/LnkSt

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Grateful and excited to launch the Otsuki Regeneration Group at the Hubrecht Institute! 🔗 www.hubrecht.eu/research-gro... We study how tissues regenerate - and use those principles to build 3D tissues in vitro. Full announcement: www.linkedin.com/in/leo-otsuk... @hubrechtinstitute.bsky.social

Thrilled to see our revised preprint now published in Nature Ecology & Evolution! If you’re curious about how to build a bat wing by re-using existing gene programs, check out the link or the tutorial below. Big congratulations to all co-authors!! Thanks to reviewers! www.nature.com/articles/s41...

This Sp9 staining ROCs 😍 (Pun very much intended — for 🐸 regen aficionados.)

🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM @ox.ac.uk supporting #cardiovascular development and regeneration research, working with #zebrafish and #human stem cell systems: my.corehr.com/pls/uoxrecru... @oxforddpag.bsky.social @idrm.ox.ac.uk (1/4)

Pls spread the word! We have a postdoc position available in the Rocha Lab @mpi-muenster.bsky.social. Join our team to study mechanisms underlying robust organ development using zebrafish embryos and human organoids. mpi-muenster.mpg.de/career

Do you like developing new AI vision methods for microscopy image analysis? You love theory & implementation? 1 week left to apply for a fully funded PhD position in our lab in Dresden 🇩🇪! Topics: object detection/tracking, multimodal models & more. DM/email for details! #PhD #AcademicJobs #GPUsgoBrr

We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something “like the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out 👇🧪🧬🐟 doi.org/10.1101/2025...

Very happy to share it’s online! If you read the preprint, updates include tracking cells and tissue flow, Histo4i timecourse (69 Abs) comparing spatial patterning emergence and a new WLS KO ipsc line establishing mechanosensing via YAP-WLS/WNT caudalizes organoids www.nature.com/articles/s41...

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

You might not have heard of the three-banded panther worm, but it's Mansi Srivastava's animal of choice for understanding the extent to which embryonic development & regeneration share common mechanisms #2025ICDB #2025SDB #ICDB2025 Related @dev-journal.bsky.social Review by @canaztekin.bsky.social

@canaztekin.bsky.social @bacell3d.bsky.social presents his work on oxygen sensitivity and the evolution of limb regeneration ! Air liquid interphase cultures to study regeneration in vitro

Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social www.nature.com/articles/s41... rdcu.be/epIB7

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

🚨 theory/math devbio preprint alert!!! 🚨 Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns: www.biorxiv.org/content/10.1...

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

Now online! Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14

Pre-print alert: This is our latest work on limb regeneration. We found that connective-tissue (CT) cells are necessary for this process by using a combinatorial approach of #spatial transcriptomics and an #ablation system for the first time in the #axolotl! 👇🧵1/6 www.biorxiv.org/content/10.1...

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980

🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...

Super cool dataset- (additionally) excited to see the hif1a data in Polypterus! more to discover about the evolutionary roots of reduced oxygen sensing in regenerating animals! :) congrats @ischneider.bsky.social and all the other authors

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

📢 We are hiring! 📢 We are looking for a postdoc to help us work out why mice cannot regenerate the spinal cord but spiny mice *can*. More info and how to apply: tinyurl.com/4m6yzbef Get in touch if interested!

🥂😎

My lab at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany offers postdoc positions in stem cell mechanobiology. www.mpi-muenster.mpg.de/departments/... drop me an email

Still an MPI für *Entwicklungsbiologie* kid at heart, but now calling FML @mpi-bio-fml.bsky.social home! #LabMove #NewNameSameGene

It’s official 🎉 I am excited to share that I will start my lab this spring at the Max Planck Institute for Immunobiology and Epigenetics @mpi-ie.bsky.social in beautiful Freiburg 🤩🗻☀️ I am looking forward to new collaborations and working with the fantastic community in Freiburg & its surroundings!

Modern tools challenge long-held assumptions - interesting findings on local oxygen levels during fracture repair! 👇 The plot thickens with the entry of 🩸 :)

Happy to share our collaborative effort showing a temporal decoupling between morphogenesis and transcription during gastruloids self-organization www.biorxiv.org/content/10.1...

Check out this cool new preprint on limb regeneration and oxygen sensing using #xenopus! @canaztekin.bsky.social www.biorxiv.org/content/10.1...