🧵 New protocol out in @cp-starprotocols.bsky.social! Step-by-step guide to infer forces in tissues using ForSys, by @borgesaugust.bsky.social, Jeronimo Miranda, Alberto Ceccarelli, Guilherme Ventura, @kuba-sedzinski.bsky.social, @hernanlopez-schier.bsky.social and I, www.cell.com/star-protoco...

Notre discipline mise en avant dans Le Monde :) Interview de l'un des pionniers de l'évo-dévo, Denis Duboule, qui parle de l'histoire de l'évo-dévo, de ses découvertes mais aussi des questions qui restent à explorer ! www.lemonde.fr/sciences/art...

🔬 Diverse species. Stem cells. Highly international team. 🐸🐭 We’re looking for a Technical Assistant to join our stem cell–based research. Interested? Apply here 👉 jobs.tue.mpg.de/jobs/276

Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...

Cambridge → Boston → Cambridge again: I’m thrilled to return to Cambridge(UK) to open my lab at the Gurdon Institute, University of Cambridge!🥳 (mzhulab.com) We study how dev timing shapes and being shaped by plasticity, evolution & ageing. 🚩Hiring at all levels: pls email me if interested!📩

🔬 Diverse species. Stem cells. Highly international team. 🐸🐭 We’re looking for a Technical Assistant to join our stem cell–based research. Interested? Apply here 👉 jobs.tue.mpg.de/jobs/276

Welcome to the team Amor!!! Looking forward to all the exciting adventures ahead 🥳

🐸Do salamanders need adaptive immunity to regenerate limbs and tails? 🐸 Nope! 🚨Check out back-to-back pre-prints from PhD student in our lab Chimezie (tinyurl.com/42wst3bh) and from our collaborators the Max Yun lab (tinyurl.com/b92rzwzr)

Two new Science studies in mice explore the roots of vertebrate limb regeneration and show that manipulating tissue mechanics, oxygen levels, and epigenetic signals can unlock regenerative potential. 📄: https://scim.ag/4sBQ93R 📄: https://scim.ag/4dL0MxA

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

Congratulations to Max Planck Research Group Leader Can Aztekin and his team on their new paper in @science.org. They have discovered how oxygen-sensing explains why amphibians regenerate limbs and mammals do not. Read the full press release here: tinyurl.com/bsuwmek6

This is amazing work. Congrats to you and the team on these incredible insights. Perfect example of why comparative biology is so important.

Check out 2 papers and a related Perspective on tissue regeneration in @science.org this week Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration | Science www.science.org/doi/10.1126/...

I've always been fascinated by #regeneration; & I have to say, my friend @canaztekin.bsky.social & his team always deliver… If anything, I feel like he’s on track to find a way to grow two extra hands to pipette while simultanously writing grants. Congrats

Not #zebrafish per se, but has big implications for the community 🤩

Congrats @canaztekin.bsky.social and everyone involved. Beautiful story on that has wide ranging implications. #EvoDevo & #regeneration at its best!

"La capacité de régénération n'est pas perdue chez les mammifères, elle est simplement inactive"

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

Thrilled to receive the 2026 Boehringer Ingelheim FENS Research Award. Exciting to see our work on brain development recognized by the European neuroscience community. Grateful to my mentors, my lab, and my family. Award lecture at FENS Forum Barcelona in July! www.fens.org/news-activit...

Excited to share our #preprint showing that #macrophages in the regenerating #zebrafish #heart are shaped by local cardiac-immune microniches, with a fibroblast-to-macrophage signal promoting regeneration over fibrotic repair www.biorxiv.org/content/10.6... @idrm.ox.ac.uk @oxforddpag.bsky.social

Let me post a spicy take here: most people don't read or cite other model organisms' work. Because of this, they keep rediscovering things and, most importantly, re-writing the timeline in favor of fewer and fewer models. That, plus an artificial limit of citations per paper equals this 🧪

New preprint from our lab! Rita Aires et al., looked into how tissue remodelling is regulated during limb regeneration. In short, depending on what tissues are injured, a tailored response ensures the right immune cells are recruited to ensure skeletal integration. www.biorxiv.org/content/10.6...

Very excited for this symposium!! looking forward to meeting everyone and learning from the community! 🤩

I am thrilled to share our new publication in @natcomms.nature.com showing that the vertebrate developmental hourglass has a cellular basis. We asked whether this embryonic pattern is already evident at the level of cells, the building blocks of complex organisms. rdcu.be/e70XT

Certain cancers are described as “glutamine addicted”. But how does this addiction arise, and how do tumors manage to bypass it? I am excited to share that the results of my postdoctoral work are finally published in @cp-molcell.bsky.social! tinyurl.com/hs7ep5sa 👇 Check the thread for more!

I’m thrilled to share that my PhD work has been just published in Cell. After a long and bumpy ride, we uncovered the core function of nuclear speckles -splicing of GC-levelled exons- and traced the evolution of this gene architecture and condensates themselves to amniotes.

A 🆕 #Ichthyosporea story Led [email protected], in Co. @gautamdey.bsky.social & @hiralshah.bsky.social+🔥team across @embl.org & @sciencesunige.bsky.social We finally have a look at what #microtubules are doing during #cellularization in #Sphaeroforma ▶️ tinyurl.com/MTSARC #ProtistsOnSky

Excited to share our work on epithelial multilayering - identifying why stem cell stay in the basal layer and how and why differentiating cells move up. Great collab with @manningresearch.bsky.social and Niessen labs! Check out preprint and great summary below www.biorxiv.org/content/10.6...

Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️‍🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M

Curious about how to achieve organ-wide #regeneration through locally controlled cell proliferation? Check out our latest computational adventure addressing this problem in the #neuromast within the #zebrafish lateral line. doi.org/10.1016/j.jt... (1/9)

Previously we had shown that axolotl tail regeneration occurs in the absence of somitogenesis. In the updated manuscript we propose that vertebral segmentation during tail regeneration occurs through a process of buckling instability. www.biorxiv.org/content/10.1...

A study from the new "Insect Sex Determination and Development research group" is featured on the front of PNAS, uncovering a conserved genetic switch for sex determination, stable across 150 million years of evolution. Read the full press release: tinyurl.com/bdzebvdf

Paper alert: Our study led by @evapillai.bsky.social and @sudimukherjee.bsky.social showing that mechanical properties of the #brain actively shape the molecular landscape during development and #axonpathfinding is finally out! www.nature.com/articles/s41... @pdncambridge.bsky.social @fau.de @MPZPM

Start your independent as an ELISIR fellow right after your PhD, in one of the most terrific places in Europe !

Interested in doing an interdisciplinary PhD to elucidate signalling centres that orchestrates limb regeneration? Come to work with the amazing @canaztekin.bsky.social and myself!!

🚨We are recruiting two PhD students 🚨 1) Quantitative & dynamic analysis of limb-regenerative signaling centers w/ @osvaldo-chara.bsky.social 📶🧮💻 🔗https://www.phd.tuebingen.mpg.de/80704/Quantitative-and-dynamic-analysis-of-limb-regenerative-signaling-center-interactions

New paper from our lab and @friedrich-group.bsky.social !! Insights into morphogen gradient scaling to regenerate a limb at the appropriate size. #axolotl, #limbregeneration

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then! www.science.org/doi/10.1126/...

🎉 Our deconstructed, stem-cell–based approach to studying signaling centers and limb-development cell types is out! 🥳 So nice to see it in its final form after the preprint— and huge thanks to the community for all the enthusiasm and interest since then! www.science.org/doi/10.1126/...

Happy to present the final version of our Cadherin and gastruloid manuscript, online at @cp-cellreports.bsky.social. www.cell.com/cell-reports... Initially in BiorXiv (www.biorxiv.org/content/10.1...) 1/12

IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇

🔬 Limb regeneration depends on regenerative signaling center cells — but how do these cells influence others to proliferate, migrate, or differentiate? We’re recruiting PhD or Postdoc candidates to explore this with our collaborator @osvaldo-chara.bsky.social !

Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

🚨JOB ALERT🚨 FRIENDS PLEASE SPREAD and RT We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility. See below 2 calls👇

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

📢 Institut Jacques Monod Seminars 📅 Oct. 7th 📍 Institut Jacques Monod Invited by the @stemdevevo.bsky.social Lab , @canaztekin.bsky.social will present an Institut Jacques Monod seminar on the theme « Signaling centers of appendage regeneration: from single cells to species » ➡️ buff.ly/Nvw4YZn

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x