Dr. Hernán López-Schier
@hernanlopez-schier.bsky.social
📤 971
📥 262
📝 124
https://lopezschier365.substack.com
Veritas vos liberabit
open.substack.com/pub/lopezsch...
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The many clocks in our body
We usually assume that we get older in sync with the ever-deepening wrinkles around our eyes. Yet, new science is finding that our body does not age synchronously.
https://open.substack.com/pub/lopezschier365/p/the-many-clocks-in-our-body?r=559xw7&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
4 days ago
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lopezschier365.substack.com/p/what-is-pr...
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What is primary focal segmental glomerulosclerosis (FSGS) and why the approval of Sparsentan matters
Understanding FSGS reveals why a recent wave of therapeutic progress, culminating in the approval of Sparsentan, is more consequential than it looks on the surface
https://lopezschier365.substack.com/p/what-is-primary-focal-segmental-glomeruloscleros
11 days ago
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lopezschier365.substack.com/p/breast-can...
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Breast Cancer Incidence and New Diagnostics
A recent headline in The National News reports that the Middle East is forecast to face a major rise in breast cancer cases by 2050.
https://lopezschier365.substack.com/p/breast-cancer-incidence-and-new-diagnostics
22 days ago
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lopezschier365.substack.com/p/turning-ba...
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Turning Back the Clock on the Aging Brain
The fog of time clouds memories. What in youth was easy to remember becomes ephemeral as we age. Yet, recent work seems to have opened a door to memory rejuvenation.
https://lopezschier365.substack.com/p/turning-back-the-clock-on-the-aging
25 days ago
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Otoferlin, Otarmeni and a new era for addressing hereditary deafness
substack.com/@yyou365/not...
about 1 month ago
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I just published in Medium some thoughts about why Food security has become an intelligence problem
medium.com/p/food-secur...
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Food security has become an intelligence problem
The future of food security will be less about producing more food, and more about building a digital system that can anticipate problems…
https://medium.com/p/food-security-has-become-an-intelligence-problem-4292612054e3?source=social.tw
about 1 month ago
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medium.com/p/21fde5137a...
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Intellectual recovery goes viral
Can a humble viral protein reset the brain stress response to restore cognition and memory in disease and old age?
https://medium.com/p/21fde5137a1c?postPublishedType=initial
about 1 month ago
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AI has an emergent problem Actually, it has a problem with emergence
lopezschier365.substack.com/p/ai-has-an-...
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AI has an emergent problem
Actually, it has a problem with emergence
https://lopezschier365.substack.com/p/ai-has-an-emergent-problem
about 2 months ago
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lopezschier365.substack.com/p/turning-fl...
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The Health Data in the Flatus
The human gut microbes turn part of the food we eat into unflattering gases. Scientists have now discovered that this metabolic exhaust provide a rich source of information about our gut health.
https://lopezschier365.substack.com/p/turning-flatulence-into-health-data
about 2 months ago
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Human-Robot Interactions Reading this work by Deng and colleagues (
www.sciencedirect.com/science/arti...
) made me think about the use of graphene/EVA-based tactile skin in robots.
2 months ago
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lopezschier365.substack.com/p/doing-this...
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Doing this for quick cash is such a bad idea
I understand that many people need the extra money now, but the forward cost is high.
https://lopezschier365.substack.com/p/doing-this-for-quick-cash-is-such
2 months ago
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lopezschier365.substack.com/p/artificial...
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Will Artificial Intelligence Help Us Sleep Better?
Sleep is not weakness. It is a daily dose of natural regeneration. And AI could help to leverage the underlying biology to helps us sleep better.
https://lopezschier365.substack.com/p/artificial-intelligence-will-help
2 months ago
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Anthropic has recently released an analysis about the projected impact of AI on the labor market
www.anthropic.com/research/lab...
My opinion follows
www.linkedin.com/feed/update/...
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Labor market impacts of AI: A new measure and early evidence
Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
https://www.anthropic.com/research/labor-market-impacts?v
3 months ago
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lopezschier365.substack.com/p/can-artifi...
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Can Artificial Intelligence Out-smart a Cardiologist?
A landmark trial is showing how AI will help, rather than replace, specialist care
https://lopezschier365.substack.com/p/can-artificial-intelligence-out-smart
3 months ago
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medium.com/@hernan365/f...
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From Tolstoy to the Mathematics of Happiness
The opening line of Leo Tolstoy’s Anna Karénina is so good that it has the sharpness of a mathematical theorem.
https://medium.com/@hernan365/from-tolstoy-to-the-mathematics-of-happiness-f98f0733a5a0
3 months ago
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I do not have a lot of material possessions, and this one is one of my most cherished. It is a hard-copy reprint of a Prof. Peter A. Lawrence FRS 1966 publication. Signed and dedicated (in Spanish), after a long discussion that he and I (still a PhD student) had about planar polarity many years ago
3 months ago
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lopezschier365.substack.com/p/approachin...
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Approaching Multiple Sclerosis with Better Diagnostics and Digital Twins
Multiple Sclerosis is often called the disease of a thousand faces, which explains why its current diagnosis lags behind those for other conditions.
https://lopezschier365.substack.com/p/approaching-multiple-sclerosis-via
3 months ago
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Are You Trying to Win a Debate, or Solve a Problem? The "Art of Thoughtful Disagreement" is a concept most prominently associated with Ray Dalio. When done well, it is one of the most powerful tools that we have to make better decisions about problems.
lopezschier365.substack.com/p/the-art-of...
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Are You Trying to Win a Debate, or Solve a Problem?
The "Art of Thoughtful Disagreement" is a concept most prominently associated with Ray Dalio. When done well, it is one of the most powerful tools that we have to make better decisions about problems.
https://lopezschier365.substack.com/p/the-art-of-thoughtful-disagreement
3 months ago
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lopezschier365.substack.com/p/how-artifi...
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How Artificial Intelligence Works (in “very, very” short)
Modern AI can feel like a magic trick. It generates stunning art, writes human-like text, writes code and devises novel strategies for complex games. But the truth is that its most powerful secret is
https://lopezschier365.substack.com/p/how-artificial-intelligence-works
3 months ago
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Very well-conducted work in zebrafish by my colleagues at the
@adrianjacobo.bsky.social
laboratory
www.biorxiv.org/content/10.6...
Which also confirms and expands the earlier discovery by Mike Deans and collaborators in mice
elifesciences.org/articles/84910
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https://www.biorxiv.org/content/10.64898/2026.02.25.708020v1.full.pdf
3 months ago
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lopezschier365.substack.com/p/tomorrow-w...
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Tomorrow Will Not Be Different
Dysthymia is a form of low-grade depression that never quite leaves. Let’s discuss why it seeps throughout every aspect of life and is so notoriously hard to treat.
https://lopezschier365.substack.com/p/tomorrow-will-not-be-different
3 months ago
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substack.com/@yyou365/not...
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Hernan Lopez-Schier (@yyou365)
Bad sleep hits the collective purse. A Epidemiology and Economic Burden of Sleep Disorders in Europe study (https://onlinelibrary.wiley.com/doi/10.1111/ene.70463) that was published just five days ag...
https://substack.com/@yyou365/note/c-217105774?utm_source=activity_item
3 months ago
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reposted by
Dr. Hernán López-Schier
Prakash Lab at Stanford
3 months ago
How self-driving cars motivated us to build a universal diagnostics platform for malaria/Tb. The arc of technology is unpredictable at best.
m.youtube.com/watch?v=gbeg...
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Self-driving microscopes
YouTube video by Cephla
https://m.youtube.com/watch?v=gbeg6mwxpd4
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lopezschier365.substack.com/p/the-subtle...
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The Upgrade of a Mother’s Brain
The brain of pregnant women undergoes profound plastic changes that will impact herself as well as her newborn. Here is a deep dive into this important, fascinating, and often misunderstood process.
https://lopezschier365.substack.com/p/the-subtle-upgrade-of-a-mothers-brain
3 months ago
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4 months ago
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lopezschier365.substack.com/p/yerba-mate...
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Yerba Mate vs. Matcha. The Lowdown
Matcha is powdered green tea coming from Asia. Yerba mate is a tea-like infusion from South America. At first glance, matcha and yerba mate seem to occupy the same niche, but they are very different.
https://lopezschier365.substack.com/p/yerba-mate-versus-matcha-the-lowdown
4 months ago
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lopezschier365.substack.com/p/the-myster...
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The Mystery of Multiple Sclerosis
Multiple sclerosis (MS) is an unpredictable disease that remains one of neurology's most perplexing puzzles. Understanding MS means grappling with a condition that can look entirely different from one
https://lopezschier365.substack.com/p/the-mystery-of-multiple-sclerosis
4 months ago
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New publication from the lab! Very excited for a the new work in collaboration with Osvaldo Chara.
pubmed.ncbi.nlm.nih.gov/41617078/
How do living systems remain stable ? We found a local feedback that acts like a quorum-sensing system, ensuring organs regrow to the right size.
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Local control of cellular proliferation underlies neuromast regeneration in zebrafish - PubMed
Biological systems are never in equilibrium, yet they maintain stability in the face of continuous external disturbances. A prime example of this is organ regeneration, during which organs are reliably rebuilt through controlled cellular proliferation. In this study, we employ a cell-based computati …
https://pubmed.ncbi.nlm.nih.gov/41617078/
4 months ago
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lopezschier365.substack.com/p/you-might-...
4 months ago
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lopezschier365.substack.com/p/the-nipah-...
4 months ago
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lopezschier365.substack.com/p/the-machin...
4 months ago
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Weak Ties with Strong Pull The American sociologist Mark Granovetter argues that loose connections linking different networks facilitate the spread of ideas and open new professional opportunities. But why?
lopezschier365.substack.com/p/weak-ties-...
4 months ago
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Flora in Ras Al Khaimah. Makes you wonder how much more life thrives in the "harsh" desert
4 months ago
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Charlie Munger’s Lollapalooza Effect Big events are rarely monocausal. Cause-Effects non-linearity happens when multiple forces align in the same direction and are not simply additive. Why understanding how forces compound is a new survival skill.
lopezschier365.substack.com/p/the-neural...
5 months ago
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lopezschier365.substack.com/p/a-vanishin...
Scientists at the State Key Laboratory of the Chinese Academy of Sciences in Beijing, China, have just developed a revolutionary soft biodegradable implant for wireless long-distance sensing.
5 months ago
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lopezschier365.substack.com/p/why-your-b...
5 months ago
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Artificial Intelligence and the Black Swan
Can AI predict Black Swan events better than humans do? Not really, but it can make us less blind to them.
https://substack.com/home/post/p-183324756
5 months ago
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lopezschier365.substack.com/p/what-to-ex...
5 months ago
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lopezschier365.substack.com/p/5-surprisi...
5 months ago
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lopezschier365.substack.com/p/how-ai-wil...
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How AI will find the next MVP
Artificial intelligence is poised to redefine sports talent scouting by measuring innate ability anywhere in the world.
https://lopezschier365.substack.com/p/how-ai-will-find-the-next-mvp
5 months ago
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And The Trophy Goes To The Digital Athlete. How a synergistic convergence of new technologies is rewriting the playbook for elite performance. The result will be significant gains with a lot less pain.
lopezschier365.substack.com/p/and-the-tr...
5 months ago
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Culture and Customs Eat Artificial Intelligence for Breakfast. If AI is not presented correctly, it could be mauled by cultural norms.
lopezschier365.substack.com/p/culture-an...
6 months ago
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lopezschier365.substack.com/p/the-non-ex...
6 months ago
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A Beginner’s Guide to Health Digital Twins How an AI-powered virtual version of you and I could change everything
lopezschier365.substack.com/p/a-beginner...
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A Beginner’s Guide to Health Digital Twins
How an AI-powered virtual version of you and I could change everything
https://lopezschier365.substack.com/p/a-beginners-guide-to-health-digital
6 months ago
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The Best Diet is Mine… Right Here, Right Now New science is showing that there is no single best diet. There is your diet for your current biology, sleep, stress, microbiome and even your postcode.
lopezschier365.substack.com/p/the-best-d...
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The Best Diet is Mine… Right Here, Right Now
New science is showing that there is no single best diet. There is your diet for your current biology, sleep, stress, microbiome and even your postcode.
https://lopezschier365.substack.com/p/the-best-diet-is-mine-right-here
6 months ago
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If Aristotle Had Access to Artificial Intelligence If you dropped Aristotle into 2025 and gave him a laptop with AI, he would absolutely love it but will ask “who is in charge of labeling the training data?” and see the risk of moral deskilling.
lopezschier365.substack.com/p/if-aristot...
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If Aristotle Had Access to Artificial Intelligence
If you dropped Aristotle into 2025 and gave him a laptop with AI, he would absolutely love it but will ask “who is in charge of labeling the training data?” and see the risk of moral deskilling.
https://lopezschier365.substack.com/p/if-aristotle-had-access-to-artificial
6 months ago
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lopezschier365.substack.com/p/ai-is-lear...
7 months ago
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lopezschier365.substack.com/p/how-artifi...
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How Artificial Intelligence Will Redefine Professional Sports
Artificial intelligence and virtual reality are redefining what it means to train, compete and recover. Welcome to the era of performance-enhancing algorithms.
https://lopezschier365.substack.com/p/how-artificial-intelligence-will
7 months ago
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lopezschier365.substack.com/p/i-know-a-l...
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I Know a Lot, and That is a Problem
The “Curse of Knowledge” can hinder conversation and professional advancement, or make job opportunities go to the best communicator rather than the most skilled or competent individual.
https://lopezschier365.substack.com/p/i-know-a-lot-and-that-is-a-problem
7 months ago
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A Deep(er) Dive on “Your Sweat Knows”
Imagine a small device that sticks to your skin like a bandaid but functions as a miniature health and performance monitor. This is the core concept behind future wearable sweat sensors. In this deep-
https://substack.com/home/post/p-177964759
7 months ago
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