How the functional architecture of the zebrafish heart is shaped during development 📹 @tobyandrews.bsky.social et al @rashmi-priya.bsky.social lab @crick.ac.uk in @cellpress.bsky.social Developmental Cell ➡️ bpod.org.uk/archive/2025...

Now published in @natcomms.nature.com! 🥳 👉 rdcu.be/eATn3 We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.

Hot off the press!!! Proudly presenting our lab's new review on how do cells communicate to control organ size :) We focus specially on dynamic connections that operate at different timescales to regulate organ growth and morphogenesis. #devbio #SizeandShape www.sciencedirect.com/science/arti...

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

New Pre-Print Alert! "Teeth Outside the Jaw: Evolution and Development of the Toothed Head Clasper in Chimaeras." We use fossil evidence, development and CT scans through ghost shark ontogeny to describe the emergence of the tenaculum! 👻🦈🦷 @karlycohen.bsky.social www.biorxiv.org/content/10.1...

Latest work: Review on the evolvability of vertebral number, and the developmental processes underpinning it Written by Callum Bucklow, @bertaverd.bsky.social, and myself Check it out here: doi.org/10.32942/X2K...

A fantastic opportunity to take on evolution with experimental embryology Great lab, mentor, department, and model system 🐠 don't miss out!

🚨📢 New paper alert! Our work showing that bilateral cellular flows display asymmetry prior to left–right organizer formation in amniote gastrulation is now published in PNAS!! @pnas.org 🥳😃 🐣 Paper link: www.pnas.org/doi/10.1073/... News article: news.miami.edu/stories/2025...

An ancient patterning system co-opted to position the chordate forebrain 🧠 Amphioxus spilling more evolutionary secrets - beautiful and rigorous work from @giacomogattoni.bsky.social (but no surprises there!)

Registration and abstract submission for YEN 2025 is officially open! We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025. Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.

Tools to analyse early heart morphogenesis in detail are limited. @noelresearchlab.bsky.social &co develop computational package called morphoHeart that allows for integrated 3D analysis of both #heart & extracellular matrix morphology in live #zebrafish embryos 🧪 @plosbiology.org plos.io/42DlqtJ

Spheroids are simple systems with only convex curvature. What about more complex systems? We teamed up with @tobyandrews.bsky.social & @rashmi-priya.bsky.social, and analyzed the ventricular myocardium of Zebrafish hearts ... and it works! 👇 (Directors: high alignment = red, misaligned = blue)

How can we accurately measure features on curved 3D tissues? 📐 Normally we rely on lossy 2D projections, but @juliaeckert.bsky.social's new method detects nematic orientation fields on surfaces of arbitrary geometry We tested it in hearts, and works a charm! 🫀 More in Julia's thread below 👇🏻

Andrews, T. G. R., & Priya, R. (2024). The Mechanics of Building Functional Organs. Cold Spring Harbor perspectives in biology, a041520. Advance online publication. #EpithelialMechanicsReview https://cshperspectives.cshlp.org/content/early/2024/06/15/cshperspect.a041520.abstract

For my first post on 🦋, I am incredibly excited to share that my PhD paper has been published in #ScienceAdvances! We compared the development of the anterior neuroectoderm to uncover how the chordate #forebrain evolved 🧠. Have a look at the summary 🧵 below! www.science.org/doi/10.1126/...

Thrilled to see #choanoflagellates on the cover of Science Advances🤩. Our latest work "Electrical signaling and coordinated behavior in the closest relative of animals" out now. Link: www.science.org/doi/10.1126/... 👏 @jeffcolgren.bsky.social @msarscentre.bsky.social

A tail of two tissues: post-gastrulation tissue scaling in zebrafish ensures proper body proportions Read this Research Highlight showcasing work from @dillansaunders.bsky.social, Carlos Camacho-Macorra & @bensteventon.bsky.social @geneticscam.bsky.social: journals.biologists.com/dev/article/...

The outer ear is a mammalian innovation but where did it come from? In our study in Nature, Mathi Thiruppathy and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. www.nature.com/articles/s41... 1/n

🎉 We're excited to share our new research in @nature.com ! We reveal that crocodile head scales self-organize through compressive folding of the skin - a mechanical twist on their development & evolution! Please read & share 🐊🔬 @genevunige.bsky.social