NEW: Epstein survivors release the most powerful PSA I have ever seen. Make this go viral so every member of the House of Representatives sees it.

My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site #microscopy #ImageJ #FluorescenceFriday #microscopyMonday imagej.net/plugins/imag...

Meningeal vascular remodeling in 2~4 mo ovariectomized🐭 ⏬blood vessel length ⏫blood vessel tortuosity ⏫PDPL+ lymphatic vessel area fraction Ectopic vessel muscularization Perivascular scattered αSMA+ cells in dura mater #Cells_MDPI 2025 www.mdpi.com/2073-4409/14...

New paper from the lab on a new Gateway compatible toolkit for transgenesis in eukaryotes, led by former technician Will Gillespie. Open access @dev-journal.bsky.social journals.biologists.com/dev/article/...

Such an iconic album. Insane.

"The Cavalier Daily corresponded with former Rector Robert Hardie, whose term ended June 30, regarding the two accounts. He confirmed that he agreed with Ryan’s account. 'I concur fully with President Ryan’s recollection of events,' Hardie said." Welp www.cavalierdaily.com/article/2025...

MAGIC Toolbox: MultiSite Assembly of Gateway Induced Clones ✨🧬 Thanks for sharing @wythelab.bsky.social! Find the plasmids here: www.addgene.org/browse/artic...

New paper from the lab on a new Gateway compatible toolkit for transgenesis in eukaryotes, led by former technician Will Gillespie. Open access @dev-journal.bsky.social journals.biologists.com/dev/article/...

108 years ago, the US military carried out the largest mass execution in American history. In December 1917, the military hanged 13 soldiers. Another 6 were hanged less than a year later. Yes...they were all Black soldiers. It's best known as the Houston Riot of 1917 🧵

See my pinned thread. Happy to have this version out!

Proud to share L'Oréal USA’s 2025 For Women in Science awardees — five brilliant women driving discovery & innovation in STEM. Honored to be quoted in the release. 🌍🧪 Read: prn.to/3Xsnila @aaas.org @aaascsew.bsky.social #WomenInSTEM #ForWomenInScience #L'OrealUSA

Many well-known perimenopause symptoms arise in the brain, but we still know little about the specific mechanisms at play. More research—both in animals and humans—is essential, writes @kundakoviclab.bsky.social. #neuroskyence www.thetransmitter.org/sex-hormones...

Our red calcium indicator, FRCaMPi, and its soma-localized version, SomaFRCaMPi, are now available from @addgene.bsky.social in various vectors, along with all the sensors used for benchmarking. www.addgene.org/browse/artic...

Single-cell atlas of intracranial arteries reveals sex-specific gene regulation linked to intracranial aneurysm risk https://www.medrxiv.org/content/10.1101/2025.11.06.25339724v1

After yesterday’s surrender, we’re launching the largest Democratic primary program that we’ve ever run. We will not back any Senate primary candidate unless they call for Schumer to step down as Minority Leader. If you’re as pissed as we are, join this campaign to rebuild the Democratic Party. 👇

The coordinated nature of this—none are facing voters in 2026—means that either Schumer approved it or failed in his job as Senate Majority Leader to stop it. Dems voting "no" get zero credit until they demand a change in leadership. Schumer out as Leader, Durbin out as Whip.

Trump and Republicans refuse to fight for American families, but I refuse to give up on them. I simply cannot vote to do nothing to help protect them from Trump’s vindictive efforts in exchange for a vague promise from the least trustworthy Republican party in our nation’s history.

KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ

Call now, leave a message, and call again tomorrow.

👇🎯 Unfortunately, this is true & probably the only way. Voters need to realize that hating government, & illegally defunding & dismantling it, & pretending that we can run a modern society/economy on Ronald Reagan's shabby talking point & worn copies of Atlas Shrugged & Mein Kampf is untenable.

If I lived in Virginia, the second that Spanberger is sworn in as governor, I'd be demanding @kaine.senate.gov's resignation so she could replace him with someone who's actually aware of what is going on.

Virginians: If you have voted for Kaine in the past, and aren't happy about this, please contact his office immediately. You may have to wait until tomorrow to call, but here's an email form www.kaine.senate.gov/contact/shar...

And now, if you read the devastating piece about what Venezuelan deportees endured at the El Salvador torture prison, read what incarcerated U.S. citizens endure in Alabama prisons. State prisons in the U.S. that are massive systems of human rights violations. www.theguardian.com/film/2025/oc...

We'll resume weekly open studio night soon, when anyone (member or no) can gather in our space to work on your own book arts+printing projects (like bookbinding, linoleum carving, zinemaking & more) while hanging out w/others doing the same. Join our newsletter to hear about these & more events:

you can see why fascism is so popular when the other option is The Loser Party That Loves Losing

@schumer.senate.gov - If you push this deal through, I promise I will donate to the person who primaries you, and donate to any candidates who primary other Dem senators that vote for this deal.

“We're seeing a level of proliferation of bodies & body piles from space that's unlike anything I've ever seen…” Human rights investigator Nathaniel Raymond explains how more people could be killed within a week in Sudan, compared to the past two years in Gaza. 🔗 zeteo.com/p/sudans-dea...

A new reporter mouse for visualising Hedgehog/GLI signalling activity This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues: journals.biologists.com/dev/article/...

Some of our most prominent colleagues continued to celebrate Watson

Beshear: Let me be clear. The president has both the funding and the authority to fund snap during a shutdown. In fact, every other president in every other shutdown has done so. People going hungry in this instance is a choice that this president has made.

A pre-trained large generative model for translating single-cell transcriptomes to proteomes www.nature.com/articles/s41... 🧬🖥️🧪 github.com/TencentAILab...

BREAKING: The Justice Department said it would file an appeal after a federal judge ordered the Trump administration on Thursday to pay food stamps in full this month www.nytimes.com/2025/11/06/u...

Ghazala Hashmi (D) has been elected Lt. Governor of Virginia, the first Muslim American to be elected to any statewide office at lieutenant governor and above.

Decision Desk HQ has called the Virginia governors race for Spanberger. The millions of dollars in anti trans ads fell completely flat there.

You Winsome, you Losesome

Happy to share STORIES out now on Nature Methods STORIES learns cell fate landscapes from spatial tramscripromics data profiled at several time points, thus allowing prediction of future cell states. Led by Geert-Jan Huizing and Jules Samaran www.nature.com/articles/s41... @pasteur.fr

'To systematically define the transcription factors (TFs) driving these states, we built a comprehensive atlas integrating transcriptional and epigenetic data across nine CD8+ T cell states and inferred TF activity profiles.' #Atlas #Immunology #Preprint www.biorxiv.org/content/10.1...

Emerging trends of fluorescence lifetime imaging microscopy (FLIM): advances, challenges, and prospects www.biophysics-reports.org/article/doi/...

scVMAP: a comprehensive platform for integrating single-cell chromatin accessibility regions with causal variants. Article: doi.org/10.1093/nar/... scVMAP: bio.liclab.net/scvmap/ scVMAP help: scvmap.readthedocs.io/en/latest/ Elucidate underlying phenotypic manifestations and pathogenic mechanisms.

Some charts for those who don't know the extent of the US public (and private) investment in research (particularly in biomedical research) compared to other countries and institutions. The destruction of the US' scientific institutions has global implications.

Beautiful bike ride up the blue ridge parkway this am, but steep! The. A fun hike and building forts for laser tag battles with the kid and his buddy

How neurons go with the blood flow when migrating through the brain. buff.ly/wIrwf4q

Paul Nurse describing the main job of a PI (From ‘The Thinking Game’, 2024)

🚨DEI firings at CBS🚨 He asks for this to be downloaded and shared. He and his colleagues deserve so much more, but this is an easy ask. We see you CBS 1/2

'Here, we present a multi-organ single-cell atlas encompassing 23 fetal and adult organs, integrating scRNA-seq & scTCR-seq fm over 2.8 million immune cells across 15 second-trimester fetal & 4 adult donors.' #Immunology

🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/

If you ever used napari in your research, take a moment to read this. Napari, like many other resources in the bioimaging world, is freely available despite the fact that it costs many people much time and efforts to develop and maintain it. Now you get a chance to give back, don't miss it :)