Rapid neuronal labeling and functional imaging in the developing mouse brain with AAV-PHP.eB

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens

Development of far-red fluorescent proteins for temporal domain multiplexing and super-resolution imaging

Detecting protein higher-order structural changes using kinase as a phospho-labeler

Real-time cell viability monitoring for high-throughput drug screening using tumor xenograft-derived cells

Parallel gene amplification by Cas9 nickase for generating functionally heterogeneous cell populations

Toward simultaneous pseudo-space reconstruction and cell-type deconvolution of single-cell spatial transcriptome using SpaDicer

Atomic elementary flux modes explain the steady state flow of metabolites in large-scale flux networks

ATACompass enables cross-species cell identity mapping for scATAC-seq without gene annotations

A generative framework for predicting cellular morphological and transcriptomic perturbation responses

Development of a human iPSC-derived corticospinal tract-on-a-chip

Reproducible detection of antigen-specific T cells and Tregs via standardized and automated activation-induced marker assay workflows

Data modeling the interplay between single-cell shape, single-cell protein expression, and tissue state

Improved expansion of peripheral blood and iPSC-derived natural killer cells for clinical applications

Quantifying reference alignment bias in functional genomics analyses

Spatial multi-omics imputation and embedding with SpaMIE

An optimized method to visualize lipid droplets in mouse brain tissue

Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC

HyPIC-3D enables characterization of migratory cancer cell subpopulations in 3D hypoxic microenvironments

In vivo visualization of bioactive iron and oxygen using LiON, the labile iron and oxygen notifier

A multiplex PCR-based sequencing method for the diagnosis and differentiation of echinococcosis using plasma samples, a proof-of-concept study

Resilience of recombinant antibiotic resistance gene-containing plasmids against common cell culture disposal methods

Human cerebral organoids with microglia and vasculature model glioma stem cell interactions and radiotherapy response

DRIFT-EM enables direct wafer retrieval of ultrathin serial sections for large-volume electron microscopy

Noninvasive focal gene transfer of chemogenetic proteins in the primate brain

High-precision stress prediction using deep energy network enhanced by stress equilibrium with Delaunay integration on refined grid

Inferring cell-specific gene regulatory networks based on causal graph embedding

Integrated multi-dimensional modeling of non-model bacteria identifies engineering targets for acarbose biosynthesis optimization

EthoPy provides an accessible platform for reproducible behavioral neuroscience

Fast and efficient Borrelia chromosome recovery from tick samples using whole-genome amplification

High-throughput histopathology for complex in vitro models

Single-molecule detection methods to study alpha-synuclein aggregation in postmortem Parkinson’s disease brains

Dissecting serum polyclonal antibody escape to SARS-CoV-2 variants by deep mutational learning

Efficiency landscape of bioorthogonal click reactions producing bispecific antibody conjugates

Genetic modification of intractable bacterial clones by heat shock-facilitated phage transduction

An improved preservation method for human dorsal root ganglion neurons enables wider access to human molecular pain neuroscience

A network-based deep learning model integrating subclonal architecture for therapy response prediction in cancer

Light-inducible FLPase reconstitution enables temporal control of gene expression in Drosophila melanogaster

HAK-actin, a U-ExM-compatible probe to image the actin cytoskeleton

A tri-modal contrastive learning framework for protein representation learning

Differential expression analysis in single-cell and spatial RNA-seq without model assumptions

ProtFI, an efficient frailty-trained proteomics-based biomarker of aging, robustly predicts age-related decline

Spatial mapping of microbial communities by an integrated automation platform of sequential FISH

R-PLA enables enhanced detection of R-loops in mammalian cells using proximity ligation

Cellular-state control using ribozyme-scaffolded miRNA-sensing and CRISPR-mediated actuation

A lightweight TcrLM model predicts T cell receptor and epitope binding specificity

A high-speed attention network for MHC-bound peptide identification and 3D modeling

Microfluidics-enabled proteomic profiling reveal iron-driven immune evasion by an antimicrobial-resistant pathogen

Multiscale domain identification for spatial transcriptomics via persistent homology

3D imaging with enhanced transparency, signal-to-background ratios, and antigen detection using HyPer-3D