We are happy to announce the hg38 Panmask Easy 151b Regions track. It contains a set of sample-agnostic easy regions where short-read variant calling reaches high accuracy and can be used to filter variant calls for clinical or research samples. More at bit.ly/Panmask

We are excited to announce the release of the CoLoRSdb small and structural variant tracks for the human assemblies GRCh38/hg38 and CHM13/hs1. Learn more about this release at: genome.ucsc.edu/gold...

We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for hg19 and hg38. The DDG2P track displays genes associated with severe developmental disorders. Learn more at: genome.ucsc.edu/gold...

Please take a moment to tell us how you use the Genome Browser: surveymars.com/q/mnb... Your feedback supports future improvements and our continued funding.

We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. Each heatmap shows the results of many small substitutions that were tested within a gene to examine their functional consequences. Learn more at: http://bit.ly/4lCIlLq

New Capture long-seq (CLS) long-read lncRNAs tracks are available for hg38 and mm10. These tracks represent the results of targeted long-read RNA sequencing aimed at identifying lowly expressed lncRNAs. See our news for more: bit.ly/CLSlongRead

We are pleased to announce new PanelApp Australia tracks for hg38/hg19 in the PanelApp composite track. These display expert, crowdsourced diagnostic disease panels for genes, CNVs, and STRs, with data distinct from the Genomics England PanelApp. More at bit.ly/PanelAppAustr...

We are pleased to announce our latest public hub, UniversalEPI ENCODE for hg38. It shows Hi-C interaction predictions based on ENCODE ATAC-seq data, generated by UniversalEPI: bit.ly/UniversalEPI_... Thanks to the Boeva Lab at ETH Zurich for creating this hub.

We are excited to announce the release of the PubTator Variants track for human assemblies, hg38 and hg19. These tracks were created using PubTator3 data and are freely accessible to the research community. Read more at: genome.ucsc.edu/gold...

We’re excited to announce support for bedMethyl and bigMethyl, new track formats for visualizing base-resolution DNA methylation from bisulfite sequencing or similar methods at single-base resolution across the genome in the UCSC Genome Browser. More info: genome.ucsc.edu/gold...

We’re adding two new UI features to the Genome Browser: a gear icon in the grey bar and an "X" to quickly remove tracks. We’d love your feedback—thanks for helping us improve! 🔗 forms.gle/s2QnMrbEYu...

We are happy to announce the release of the Bionano DLE-1 track for human assemblies hg38 and hg19. These tracks show the CTTAAG sites used by the Bionano Optical Genome Mapping system, an assay to detect structural variants. Learn more at: genome.ucsc.edu/gold...

New ENCODE4 long-read RNA-seq transcripts track for hg38 and mm10. Triplets (e.g. [1,1,3]) indicate start site, exon combination, and stop site for each transcript. Enrichment scores show how these change across tissue and cell line samples. Read more: genome.ucsc.edu/gold...

We have two new pathogenicity prediction score tracks available in our Deleteriousness Predictions super track: MCAP and MutScore! Both are aimed at interpreting the pathogenicity of variants in a clinical setting. See our news for more: bit.ly/UCSCmutScoreMCAP

We are happy to announce the release of the Unusually Conserved Regions track for GRCh38/hg38. For more information about the release, please read the news announcement: genome.ucsc.edu/gold...

We turn 25 today! July 7th marks the 25th anniversary of the human genome going online and the start of the UCSC Genome Browser. Then vs. now, we have 165k monthly visitors, and our codebase is over three million lines of code. See our news for more: bit.ly/genomeBrowser...

We have a new training page with updated tutorials covering our most popular tools. Each includes an annotated screenshot, guided walkthroughs, and an interactive click-through tutorial. See our news for more: bit.ly/genomeBrowser...

We are pleased to announce the release of the All GENCODE tracks for hg19, hg38, and mm39. These tracks correspond with the Ensembl 114 release. Learn more about the release from the following news post: genome.ucsc.edu/gold...

We are happy to announce the release of the EVA SNP Release 7 tracks, now available for 40 assemblies and covering nearly 910 million variants. Learn more at http://genome.ucsc.e....

Are you at #eshg2025 ? Visit us at booth 226! We will also be co-presenting a workshop on Monday, 5/26, with @ensembl at 14:15.

We are excited to announce the release of the Varaico tracks for human assemblies hg38 and hg19. Varaico stands for "Variation Research Advancing Insight in Complex Organisms". Varaico was created using literature mining, similar to AVADA. Learn more at: genome.ucsc.edu/gold...

New tracks now available: GENCODE "knownGene" V48 for human (hg38/hg19) and VM37 for mouse (mm39). Read more about this release in this news post: genome.ucsc.edu/gold...

We have a new Recommended Track Set (RTS), Exon Relevance, and a new track, gnomAD Proportion Expression Across Transcript Scores (pext) for hg38. The pext track shows @gnomad-project.bsky.social data in combination with GTExV10 to compute a metric quantifying isoform expression for variants.

We are happy to announce an update to the VISTA Enhancers tracks for hg38, hg19, mm39, and mm10. Learn more about the release from the following news post: genome.ucsc.edu/gold...

Huge thanks to the teams whose work inspired Gencube: 🔹 GenArk team (e.g., @genomebrowser.bsky.social ) 🔹 Ensembl Beta ( @ensembl.bsky.social ) 🔹 Zoonomia Consortium ( @elinork.bsky.social & @KltLab) Your contributions to scalable infrastructure and comparative genomics were truly foundational. 🙏

& genome browser from @genomebrowser.bsky.social (with their recommended track sets for variant interpretation) www.deciphergenomics.org/gene/fbn1/ov... genome.ucsc.edu/cgi-bin/hgTr...

Announcing the new Pseudogenes track for hg38! The composite track contains pseudogene predictions and their corresponding parent genes, as identified by PseudoPipe. This release includes the Pseudogene Parents and Pseudogenes tracks. Learn more at genome.ucsc.edu/gold....

A new hub has been added to the Public Hubs listing, EPIration - an atlas of candidate enhancer-gene interactions in human tissues and cell lines. View this hub using the following URL: genome.ucsc.edu/cgi-... We want to thank the @guigolab.bsky.social for making this data available.

We are excited to announce the release of two denovo-db tracks for hg19/GRCh37. denovo-db is a curated database of germline de novo variants in the human genome, defined as variants present in children but absent in their parents. Learn more at: genome.ucsc.edu/gold...

We are excited to share new AlphaMissense tracks for the hg38/hg19 human assemblies. AlphaMissense scores predict the pathogenicity of missense variants for all possible single amino acid substitutions in the human proteome. See our news for more: genome.ucsc.edu/gold...

We are pleased to announce the release of the MITOMAP track for hg38/hg19. MITOMAP is a human mitochondrial genome database. This release includes the MITOMAP Control and Coding Variants track & the MITOMAP Disease Mutations track. Learn more at genome.ucsc.edu/gold....

We are excited to announce the new Splicing Impact super track for hg38 and hg19. This super track includes AbSplice Scores, SpliceAI, and, for hg38, the new SpliceVarDB track. Learn more at http://genome.ucsc.e....

We are happy to announce the release of new highlight features for track hubs. Items can now be striped with a colored background to appear "highlighted" compared to the other items in the display. Learn more about this release at: genome.ucsc.edu/gold...

We are excited to announce the release of the enGenome VarChat track for hg38 and hg19. This track uses AI to search papers for variants, providing information such as its gene, HGVS nomenclature, and dbSNP rsID. Learn more at genome.ucsc.edu/gold....

The Clinical Interpretation of Variants in Cancer (CIViC) track for hg19/GRCh37 and hg38/GRCh38 is now available. The details page for a feature will list diseases and therapies that have been associated with a genomic variant. Learn more at: genome.ucsc.edu/gold...