Adieu @tobyandrews.bsky.social you will be missed... You’re off to an incredible start, and I couldn’t be prouder. Onward and upward!

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains 1/ doi.org/10.1101/2025...

Our first extraordinary biologist featured this week is Katherine Brown, @biologists.bsky.social Publishing Director and former @dev-journal.bsky.social Executive Editor, who has been closely involved with @prelights.bsky.social since its inception. #100biologists @katherine-brown.bsky.social

🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

Ventricle position can be remodeled after heart looping! In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers. So grateful to all the authors for their expertise and input during this long (but fun) ride 💪 Read more here ⬇️

📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. @sreejithsanthosh.bsky.social biorxiv.org/content/10.1...

In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers. There are now over 10,000 trees for peer reviews! Thank you to all our peer reviewers. Find out more: forest.biologists.com #PRW2025 @peerreviewweek.bsky.social

Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social More info below ⬇️

Don't miss your chance to contribute to Development's next special issue, which takes a non-cell-centric approach to devbio, stem cells & regeneration. We hope to capture papers that discuss how secreted factors, external forces and the shape of spaces instruct development. #DevSIextracellular

A snapshot of the mechanics shaping organs: what plants and animals can teach each other. Thank you Mabel, @MabelMathew_M and Ankita @Dash_Ankita for putting this together. authors.elsevier.com/a/1lamy3si8Q...

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

Heading to the International Congress on Invertebrate Morphology in Chile? 😄 Don’t miss the talk by our PhD student Alena Kizenko on Aug 12, on how an ancient cytoskeletal gene found a new role in tunicate development 🧬 #EvoDevo #Invertebrates 🎥👇 Developing Phallusia embryo

✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪 #FluorescenceFriday #DevBio

Thank you @the-node.bsky.social‬ for inviting me to write a 'Behind the Story' piece on our recent study! Exploring the Uncharted Waters of Endothelial Tip Cell Migration: A Story of Aquaporins, Hydrostatic Pressure, and Angiogenesis thenode.biologists.com/exploring-th...

We wrote this introductory review on how concepts from dynamical systems can help us understand developmental biology, hope it’s useful to somebody! It was a lot of fun to put together, and great to collaborate with brilliant colleagues across theory and experiments

We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum. First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social rdcu.be/ezBl7

Out now! Our very first [email protected], an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️ www.cell.com/developmenta...

Researchers at the Crick have discovered that the heart’s contractions trigger biological signals for its own development. Their study in zebrafish highlights the heart’s ability to remodel itself in response to biological challenges. www.crick.ac.uk/news/2025-08...

Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

My Pathway to Independence interview is now live on @dev-journal.bsky.social ! I had a great time speaking with @amjeve.bsky.social about my research journey and what's ahead journals.biologists.com/dev/article/...

Happy to share our work on the role of biomechanical PULSATILITY on lung vessels. Following surgery to alleviate overload in kids with single ventricle hearts, lung arteries form AVMs. #DevBio #EndothelialCell #CHD Beautiful work from Steve Spurgin. #DevBio 🫁 🫀 ❤️‍🩹 www.biorxiv.org/content/10.1...

Transitions in development – an interview with Jeffrey Farrell @jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches. journals.biologists.com/dev/article/...

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

Our new paper is out! 1/14 How does an organ rebuild its shape after injury? It's not just about making new cells, but aligning them in the right direction — like bricks shaping a structure. We show that it's all driven by Cell Geometry! www.cell.com/current-biol...

Paper accepted 🥳 Many congratulations @tobyandrews.bsky.social So proud of what you have achieved! Can’t wait to see what you do next... Onwards and upwards from here!

Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Find more information and register at: events.faseb.org/event/Mechan... Submit abstracts by August 31, 2025. Please share and see you in October!

Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

Excited to share our paper on deciphering the design & control principles of tissue scaling w/ Luisa Arispe! Amazing work by co-first authors Danielle Pi and Jonas Braun. We show *differentiated* endothelial cell proliferate in waves with ultrafast cell cycle time of ~5h www.cell.com/cell-systems...

🚨 Join us tomorrow for this really exciting talk on the interplay between morphogen signalling and tissue organization! 🚨

Transitions in development – an interview with Natalie Dye In this interview, @natalieadye.bsky.social talks about her research interests, her path to becoming a group leader @mbisg.bsky.social, and the importance of finding a supportive network of peers and mentors. doi.org/10.1242/dev....

Latest #MetabolismMondays interview has just dropped 👀 Find out more about #newPI @kstapornwongkul.bsky.social and her research 👇

This was a fun exercise... reflecting on my accidental path into science, the questions that drive our lab @crick.ac.uk , and thoughts on building a more inclusive scientific community. Grateful for the opportunity @focalplane.bsky.social and Subhajit .

Thank you for the kind words and highlighting this milestone. I’m thrilled and honoured to have reached tenure. Big thanks to my lab, colleagues, mentors, friends and family who’ve supported me along the way. Excited to keep doing what I love - now with slightly more security.

Hard to remember that just 12 years ago there was no @biorxivpreprint.bsky.social and almost no one in the biology community preprinted their work. What a long way we’ve come. @reinierprosee.bsky.social and I wrote a thing about how @biologists.bsky.social embraced the preprint world

Very happy to share it’s online! If you read the preprint, updates include tracking cells and tissue flow, Histo4i timecourse (69 Abs) comparing spatial patterning emergence and a new WLS KO ipsc line establishing mechanosensing via YAP-WLS/WNT caudalizes organoids www.nature.com/articles/s41...

A decade of preprints in biology How @biologists.bsky.social has championed preprint adoption since 2014 Launching preLights, supporting Review Commons & introducing In Preprints in @dev-journal.bsky.social

🧵Just out ! We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration. Here’s the story👇 authors.elsevier.com/c/1lM285Sx5g... Work done in @frelab.bsky.social at ‪ ‪ @institutcurie.bsky.social

Happy to be the next (and 1st female) @crg.eu director. The CRG always stood out to me, for its excellence in understanding life's principles, with implications for health and biodiversity, & its collaborative, open and innovative way of doing science. Thrilled to join its amazing community in 2026!

📢Early Bird Deadline Extended to July 15! We have extended the deadline for InSDB-ISD early bird registrations to July 15. Don’t miss your chance to register at discounted rates-register now! insdb.in/events/insdb...

Delighted to share our latest work on the mechanisms of epithelial curvature and 3D morphogenesis ! Amazing work from newly graduated Dr @courtneyl7a7.bsky.social 🎉 @lmcb-ucl.bsky.social @uclnews.bsky.social @ucllifesciences.bsky.social www.sciencedirect.com/science/arti...

Very excited to share the first preprint from the lab: www.biorxiv.org/cgi/content/... We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations. Want to know of they cope with feeling squeezed? 🐟🐠🐟

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

In the latest episode of 'Behind The Bench', Sundar Naganathan talks to InSDB about his research journey and work @tifrscience.bsky.social. Read the interview here: insdb.in/behind-the-b...

📣 New paper out! How do thousands of cells shape the emergent geometry of the avian embryo? We identify distinct, independently controllable mechanisms that contribute to embryo size and shape. @alex-plum.bsky.social @bensteventon.bsky.social @Guillermo Serrano Najera www.nature.com/articles/s41...

‘These cracks, they let the developing cells in: A chronicle of trabeculation in the developing zebrafish heart’ 🎵 Theodora Stougiannou highlights recent work from @rashmi-priya.bsky.social & team. #preprint Check out the #preLight ⬇️ 👀 prelights.biologists.com/highlights/m...

What a fantastic essay by last year's @mblscience.bsky.social Embryology students! A perfect paean to the most wonderful science: "It's exhausting; it's exhilarating; it's Embryology." journals.biologists.com/dev/article/...

New from our lab @crick.ac.uk, in collaboration with the Enchev and Bukau labs. By studying a protein that is difficult to fold, we discover fascinating new mechanisms by which the ribosome supports protein biogenesis. www.biorxiv.org/content/10.1...