Excited for the #CSHAmeeting on Human Development - From Embryos to Stem Cell Models in Suzhou, China? Our Editor, Peter Rugg-Gunn, is attending and has curated a collection of review-type and Research Articles on this topic: journals.biologists.com/dev/collecti...

On the train back now from the 2nd ever #EMBODevMet, where I got to see many familiar faces, meet new people, and hear about lots of great and inspiring work combining two of my top scientific interests (development & metabolism) in so many different systems! 🤓🤩

Beautiful work from Nan Xu and the @studerl.bsky.social lab in @natcellbio.nature.com combining directed differentiation of hPSCs and genome-wide CRISPR screens to identify the epigenetic factors Menin and SUZ12 as regulators of developmental pace across germ layers. www.nature.com/articles/s41...

Congrats to authors on this preprint!🦈 brains, what’s not to like? *Deep conservation in brain basal progenitors. Cool!

Super excited that our latest work is out! We use optogenetics to dynamically control and study the formation of morphogen gradients. If you are interested in optogenetic tools and/or how cells shape and process extracellular signals, check out @jamesbriscoe.bsky.social's thread and the paper.

Read more about @sermenchero.bsky.social 's work in this PNAS Journal Club. #opossums!

Why would anyone want to be a scientist? 👩‍🔬 Very much enjoyed this piece. Of course there may be other reasons, but these resonate well with me. A reminder for all of us that I find rarely mentioned: “Great work becomes part of the background”

“Our findings suggest the existence of tens of thousands of enhancers that remain undiscovered by currently available chromatin data, underscoring the continued need for expanding resources for enhancer discovery.” Great paper and very important finding - many congrats Axel & team! 👏👏

Hi bsky! Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity! w/ A. Delahaye & ‪@bensteventon.bsky.social‬ shorturl.at/v01DO

In preprints: setting the tempo of development @gabbov.bsky.social and @mdiazcuadros.bsky.social highlight two preprints that describe how developmental timing is set by cell-intrinsic mechanisms. journals.biologists.com/dev/article/...

🔥🔥🔥🔥🔥🔥 Worth a read if interested in developmental timing & heterochronies. What a beautiful work in an unusual model organism. Congrats Sergio et al!!!!

Found this unbelievably accurate “integrated stem cell model” by JA Thomson in 1996 of marmoset ESCs 🐒 pubmed.ncbi.nlm.nih.gov/8828827/ The simplest protocol one can think of built quite remarkable structures !?!?

Happy #MicroscopyMonday! This video, captured by Berta in the @trayon.bsky.social lab in collaboration with our Imaging facility, shows a mouse embryo dividing. This video allows researchers to visualise the events that happen before implantation at an early stage of development.

Really excited to visit the Karolinska Institute: dev brains & spinal cord!!

Tight control of Notch1 intracellular domain (NICD) stability to tune devel- opmental timing in the context of human somitogenesis. Original paper: genesdev.cshlp.org/content/gene...

🚨Symposium alert! 🚨 Next edition of our biennial stem cell symposium is 4th Dec 2025 - focus on metabolism and development. Sponsored by @bsdb.bsky.social. Great lineup of speakers, hosted @mrc-lms.bsky.social in London. Registration is open. www.symposia.org.uk/courses/stem...

Tomorrow we'll welcome the EvoDevo community from UK and beyond @qmulsbbs.bsky.social @qmulse.bsky.social , organised by @chemamd.bsky.social @margaridamcm.bsky.social @ferdix.bsky.social @alexdemendoza.bsky.social , Roman Arguello and James Difrisco. Poster by former lab member Giacomo Mogglioli

Bravo!!!!!

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

Terrific rallying cry of an @socdevbio.bsky.social award lecture from @mads100tist.bsky.social at #icdb2025! Our work and community are important, #DevBio matters, and it’s up to us to tell everyone why. Don’t give the enshittifiers an inch!

What happens when passion, creativity and fun collides - you end up dressed as a rhodopsin protein rapping to an international audience as part of @eu-life.bsky.social's #ScienceVision contest! Get Ellie's perspective in this interview ⤵️

What can we do? First, think twice before sending your work to a for-profit publisher. Second, IGNORE ALL REQUESTS from these publishers. Do not subsidise their business model. Third, tell your boss to tell her boss. Change happens when the funders take action.

May has been quite the month… The #EvoDevoConference was a blast 💥 Thanks to all participants and organizers for your engagement! @mdiazcuadros.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social 📸 (1/2)

There is no replacement (yet) for animal models in medical research 🔬 🪰🐭🪱🐠

🚨Preprint alert!🚨 Great collaboration with the lab of Stefan Schoenfelder @stefanschoenfelder.bsky.social - we dissect the role of non-canonical enhancers in human pluripotent stem cells. 👇

These include: - Only ~ 50% of all tested H3K27ac+ enhancers are active in vivo (Vista Enhancer Browser) - H3K27ac is dispensable for enhancer function in mouse embryonic stem cells - Some genomic regions lacking H3K27ac enrichment function as genuine enhancers (e.g., Pradeepa Nature Genetics 2016)

Congratulations Stefan & team!!! Fell in love with the story the minute I heard it @babrahaminst.bsky.social 👇🏻👇🏻👇🏻

Check out our new work building dynamical landscapes to understand cell fate decisions. This has been a true adventure and long-term interdisciplinary collaboration. I think I'll add one more language in my resume - I can speak to mathematicians 😂

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

'Rapper Rhodopsin' (AKA Ellie @trayon.bsky.social lab) and the Babraham Massive celebrating Ellie's victory in the first ever @eu-life.bsky.social Science Vision contest. We're so proud! Thanks @ceitec.eu - it was so much fun!

🚨We’re proud that The Genetics Society @gensocuk.bsky.social supports the upcoming UK EvoDevo meeting. Register for only £5 and submit your abstracts before June 1st! Link to register: eshop.qmul.ac.uk/conferences-...

A much needed resource for the community. Thanks 🔥🙏 👏🏻👏🏻

Featured in The Guardian! www.theguardian.com/science/2025...

The @embo.org #EvoDevoTempo ⏳ Paris 2025 just came to an end ⏳🧬 So grateful to be part of this inspiring community! Tons of ideas to take back with me - and already looking forward to the next edition! 🚀

Check out this position - Barbara’s research is top and she is an amazing supervisor!

Any chromosome biologists looking to relocate should get in contact! chromosome.ie

The @embo.org practical course on #lightsheet #microscopy is back! Join us in #Dresden for 2 weeks with #your #samples, try the complete line-up of #lightsheet microscopes, tackle big data image analysis, sample prep, OA hardware & much more Apply now! Repost 🙏 meetings.embo.org/event/25-lsm

#FERTILITY A discovery by scientists in Canada and Sweden opens new possibilities for therapeutics aimed at ensuring a healthy pregnancy. @crchum.bsky.social @ki.se @naturecellbiology.bsky.social nouvelles.umontreal.ca/en/article/2...

A great article highlighting the broader implications of the three parallel recent papers from our group and our wonderful colleagues in Spain and Belgium...

Well deserved recognition for an incredible scientist at all possible levels. Can’t wait for your next discoveries. Congrats 🍾🎈🎉 🎊

Congratulations to everyone shortlisted for a 2025 Papin Prize! We are delighted to congratulate Simon Andrews @babraham-bioinf.bsky.social for being shortlisted in the Contribution to Research category and Rita Dapaah, Flow Cytometry Assistant, for being shortlisted in the Best Newcomer category 👏

If you’re a PhD or postdoc developmental biologist in the UK who cares about the field and the community, please nominate yourself to join the BSDB committee. Great opportunity to get involved, have real input and give back to the community @bsdb.bsky.social #biologists100

Deadline for abstract submission & registration approaching (April 1st) The time is now!!!! #EvoDevoTempo ⌛️⏳

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980

On International Women’s Day a reminder to continuously support each other. #womeninscience

@odedrechavi.bsky.social is doing the next Woodstock of Biology The next installment is in Prague. He promises exciting and fun science. woodstock.img.cas.cz/program/ please spread the word

Well done & congrats everyone for this fabulous meeting "for postdocs by postdocs" 👩‍🔬🔬🧬

🎉 That’s a wrap! The International CRG-BI Postdoc Symposium has come to an end after three incredible days of inspiring talks, engaging discussions, and valuable connections. I have to say I couldn’t be happier! #CRGBIpostdocs A 🧵 below 👇🏼

"Developmental Timing Across Species" @embo.org Workshop organised by @trayon.bsky.social @bassemh.bsky.social @mdiazcuadros.bsky.social @vanderhaeghenp2.bsky.social 📅6-9 May 2025 📍Paris Submit abstract and register by 1 April: thenode.biologists.com/developmenta... #EvoDevoTempo