RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...

heads up neuro bsky 😎 must-read seminal discoveries: ultimate translation of genetic information in the farthest reaches of the neuron ➡️ @erin-schuman.bsky.social & in cortex development ➡️ @debbysilver.bsky.social thanks again 🤝 @natrevneuro.nature.com Darran Yates for editorial collaboration

Lates from the Briscoe lab: Lineage tracing of neural progenitors in 🐤& 👤 - demonstrates sequential binary decisions & persistence of spatial identity despite temporal competence changes. Congrats to Giulia and co 🍾🥂

And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n

Very sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...

We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social 🔥 now including in vivo 🐭&👤 embryo data www.biorxiv.org/content/10.1...

Beautiful work from Nan Xu and the @studerl.bsky.social lab in @natcellbio.nature.com combining directed differentiation of hPSCs and genome-wide CRISPR screens to identify the epigenetic factors Menin and SUZ12 as regulators of developmental pace across germ layers. www.nature.com/articles/s41...

New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

Excited for the @isscr.org‬ meeting in Hong Kong this week? #ISSCR2025 We've curated a 'Focus on stem cells' collection to complement the meeting, highlighting recent research and review-type articles discussing the wide range of studies using #stemcells. journals.biologists.com/dev/collecti...

Today we've announced the new Faraday Fellowship accelerated international route, which will grant up to £30 million in funding over the next two years to attract global talent and support the development of world-leading research groups in the UK: #RSGrants royalsociety.org/news/2025/05...

So proud of this work finally out in @natmicrobiol.nature.com! We examined antigenic variation in malaria parasites at single-cell level and found a surprising level of diversity. Make sure to check it out and don’t miss my talk on Thursday to hear about this story! #malaria #scRNA-Seq #EMBLMalaria

Hi @marklewandoski.bsky.social , You are already on the DevBio II starter pack. Please check to make sure you can see your @ handle. Devbio I was filled to its max of 150 members many months ago. So U stated a second pack which is almost full. go.bsky.app/2qUqVKE

@rrbehringer.bsky.social the first Dev Bio starter pack: go.bsky.app/M5AgJhn

The @embo.org #EvoDevoTempo ⏳ Paris 2025 just came to an end ⏳🧬 So grateful to be part of this inspiring community! Tons of ideas to take back with me - and already looking forward to the next edition! 🚀

As this @embo.org EvoDevoTempo Paris 2025 comes to close, my biggest takeaway message is that we absolutely must do this again! Cheers to the organizers and thanks for all the feedback on our work from the lovely Tempo community Until next ⏰ time ⏰

I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...

Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by @biologyopen.bsky.social More innovation from @biologists.bsky.social Details here: www.biorxiv.org/content/10.1...

Thrilled to start my collaboration in Lorenzo Calviello’s lab @translatomics.bsky.social at @humantechnopole.bsky.social! Excited to dive into Ribo-Seq, exchange ideas and uncover new insights on translational regulation. Looking forward to what’s ahead! Let’s get started! 🧬💻✨

Job opening in my research group!! Please share. I'm looking for a lab technician to join my small team investigating how chromatin structure regulates gene expression in C. elegans. www.fmi.ch/education-ca...

🚨New preprint alert!!! We show using #Celegans that mothers control the #ribosome levels of their offspring depending on their diet. Pioneered by fantastic Sigma Pradhan (not yet on 🟦). #worms biorxiv.org/content/10.1.... 🧵

Last week, postdocs from @crg.eu & @babrahaminst.bsky.social came together to organise the International Postdoc Symposium, 2 incredible days full of science, dialogue & networking. These collaborations are so important! And Iris Uribesalgo, EU-LIFE Policy Officer, was there to talk about her role 😊

It was great to participate in this #scicomm session and have a chance to present some of our recent #SciArt projects! I enjoyed very much to listen about other projects! Thank you #CRGBIpostdocs !

🎉 That’s a wrap! The International CRG-BI Postdoc Symposium has come to an end after three incredible days of inspiring talks, engaging discussions, and valuable connections. I have to say I couldn’t be happier! #CRGBIpostdocs A 🧵 below 👇🏼

A big thanks to the #CRGBIpostdocs organizers for an amazing conference.

Thanks so much to all the organisers at @crg.eu and @babrahaminst.bsky.social for the amazing opportunity to present my PhD work at the #CRGBIpostdocs conference! Time to hit the beach 😎😎

It's amazing to be in the sunny Barcelona for #CRGBIpostdocs symposium and to be presenting my postdoc work. Many thanks to the organizers for the excellent opportunity. Great science shared and more to come tomorrow.

Such an inspiring discussion on how to disseminate science. It's all about making your research seen, heard and felt! Huge thanks to the panel members #CRGBIpostdocs @crg.eu @babrahaminst.bsky.social

Who knew development could be this exciting! Then again, they were preaching to the choir 🤍 amazing talks from Nicolas Rivron, @irenezorzan.bsky.social, @komal-yasmin.bsky.social , good discussions, and lasting friendships and collaborations 😎 @babrahaminst.bsky.social @crg.eu

Well done, Raj! 👏 It is great to see so many EU-LIFE institutes coming together for the @crg.eu / @babrahaminst.bsky.social International #Postdoc Symposium If attending, don't miss the discussion on career development with an amazing panel of speakers incl. EU-LIFE Policy Officer Iris Uribesalgo!

Now that we are in Barcelona we have jumped right into some fantastic science! From chromatin structure and pathogenic fungi to having a deep and existential think about our omics approaches 🤔 😎 #CRGBIpostdocs @crg.eu @babrahaminst.bsky.social

With the #CRGBIpostdocs symposium underway, we're shouting out our Babraham speakers! First up is Alex Whale from the Houseley lab, speaking at 4.30pm today. He'll talk about extrachromosomal circular DNA and the emergence of drug resistance 🧫

🚀 Off we go! ✈️ An early flight to kick off the International Postdoc Symposium! @crg.eu @babrahaminst.bsky.social Excited for an inspiring few days ahead! #CRGBIpostdocs

🚀 The countdown is on! The International Postdoc Symposium is happening Feb 26-28, bringing together @crg.eu & @babrahaminst.bsky.social postdocs for insightful talks, engaging discussions, and plenty of opportunities to connect. Can’t wait to see everyone there! #CRGBIpostdocs

Don’t forget to apply! This is an amazing opportunity!

Latest from the lab! I've been seeking the ultimate modulator that regulates the tempo of multiple developmental processes simultaneously, and metabolism has been an attractive candidate for such a global tempo modulator. However, I was wrong. 1/ www.nature.com/articles/s41...

Looks like a great workshop! Here's a snapshot of sessons: ⏳ Developmental timing in vivo ⏳ in vivo & in vitro models for timing ⏳ Metabolic rates and timing ⏳ in vitro & in silico models for timing ⏳ Cell dynamics and timing ⏳ Timing in homeostasis ⏳ New molecular mechanisms of timing

I am very excited to share our most recent work on how ‘Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration’ ☺️ Thanks a lot to @silviabarbiero.bsky.social @davidbrueckner.bsky.social @priscaliberali.bsky.social @ehannezo.bsky.social and all the co-authors!

Great thread for 2024! Looking forward for 2025 ⏳ #EvoDevoTempo

A selection of papers in 2024 associated with developmental timing & mammalian pausing. 🐭⌛️👤⏳ #EvoDevoTempo 1/n

Looking forward! ⏳

This is a lovely piece about the 2024 Nobel Prize to Victor Ambros and Gary Ruvkun, written by Bruce Wightman, the first author of one of the prize-winning papers. It emphasizes the importance of fundamental research and the beauty of heterochronic genes. #Celegans #devbio 🧪🧬 doi.org/10.1242/dmm....

2nd edition of the EMBO Workshop on Dev timing & evolution will take place in Paris. 6-9 May 2025. Save the date!!! coming-soon.embo.org/w25-105