Really interesting new findings about the human appendix, an organ which most people know very little. Evolution Keeps Reinventing The Appendix. Here's Why It May Be Important. : ScienceAlert share.google/jRnSs6hLLXA9...

We have a new paper out today from superstar Nora Herzog! A virus that fluidizes the nucleus to enable replication! Check it out here: lnkd.in/e-xV8acK This was an amazing collaboration with Ian Mohr and Angus Wilson

Had an absolutley brilliant time at #KSEmbryology26 a few weeks ago and was really inspired by all the great talks and posters there 🤩 Here's a list of the #preprints I noticed from presenters 👇 - check it out and please let me know if I've missed any! prelights.biologists.com/prelists/key...

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)

Our newest work on quantification and statistical testing of scoliosis severity using microCT and R. www.cell.com/star-protoco... Thanks to @eceatayeter.bsky.social @brittneyvoigt

Nice review from Kate Adamala of Adrian Woolfson's new book On The Future of Species. www.nature.com/articles/d41...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here: rdcu.be/e5EgU #EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

From our new paper out now in @currentbiology.bsky.social: www.cell.com/current-biol... w/ @neurofishh.bsky.social @gkafetzis.bsky.social @denilsson.bsky.social Looking across animals, the vertebrate eye is an obvious outlier. Why is it so different that other highly visual animals?

Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....

Looking forward to @keystonesymposia.bsky.social, @ebisuyamiki.bsky.social and @jun-wu-lab.bsky.social's #KSEmbryology26 meeting starting this evening? Feel free to come say hi and grab a poster for your lab/office

The heartbeat and other bodily processes play a surprising role in shaping perception and cognition. (From the archive) www.quantamagazine.org/how-your-hea...

Here is a robust biochemical & functional difference between young and old mammalian cells: - The fraction of new amino acids incorporated into proteins. The difference is consistent, quantitative, cell-type specific, and deeply intriguing. What aging mechanisms cause it ? 1/

Feb 11 is International Day of Women and Girls in Science and at RIKEN BDR, we celebrate the achievements of #womeninscience by holding an IDWGIS Symposium. We also recently launched Mirai Alliance, a mentorship network for women researchers in life sciences. www.bdr.riken.jp/en/news/bdr-...

Happy to announce that our latest paper is now out! Have you ever wondered how neural tissues control their size? In this paper, we show that cell division orientation is critical in both the cortex and retina. www.science.org/doi/10.1126/...

⚡👩‍🔬Electrical signals are key for promoting organ regenerative growth, a new study! Out now in Science Advances, from the Mateus group @ritamateus.bsky.social at PoL and @mpi-cbg.de along with the lab of Frank Jülicher @mpipks.bsky.social Read the news here: tud.link/7jzptz Video:©️ Mateus group

Why is it that small animals like insects have a landspace body plan when viewed head-on, but larger animals like elephants are taller than wide? With @m-v.bsky.social, we find out in our new preprint titled 'Size and shape of terrestrial animals' - arxiv.org/html/2602.00...

Our paper on the evolution of XIST regulatory network in primates is now published in Science Advances! Check out the paper www.science.org/doi/10.1126/... or a digest of our findings emmanuelczt.github.io/posts/2026/0... A short 🧵 of our main findings 👇

AlphaGenome is out in @nature.com today along with model weights! 🧬 📄 Paper: www.nature.com/articles/s41... 💻 Weights: github.com/google-deepm... Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Excited to finally share the final/final.doc version of our paper. It's been a journey, but very proud of the result. Well done to all involved, especially @elsieplace.bsky.social @kchinnaiya.bsky.social , @thomasdwkim.bsky.social, @sethblackshaw.bsky.social 👏👏 www.nature.com/articles/s41...

(1/2) Our work with @freddyfrischknecht.bsky.social on the chirality of malaria parasites has found its home in the January issue of @natphys.nature.com: www.nature.com/articles/s41... Moreover, we are very happy that it comes with a news and views article 👍❤️😀

Researchers have engineered magnetically controlled fluorescent proteins that can be remotely dimmed and brightened in cells and living animals go.nature.com/3NUSY12

New paper presenting rather compelling evidence that the stem-vertebrate Haikouichthys had paired lateral and supranumerary medial eyes (!!!), and proposing that the medial eyes may have deep homology with the pineal and parapineal organs. www.nature.com/articles/s41...

A loving family of tiny bats in Panama 🦇🦇🦇 Likely resting on a tree trunk due to the lack of nearby caves. Fascinating how they remain upside down even while clinging on.

@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social www.biorxiv.org/content/10.6...

More than 400 million years ago, during the Silurian Period, an evolutionary event led to the later emergence of spiders’ spinnerets—the abdominal organs that make silk—according to new #ScienceAdvances research. https://scim.ag/4sFX3pJ

Nice summary on our paper on mechanisms controlling development and evolution of the cone-dominant ground squirrel retina, which is now in final form at eLife. www.lifescienceeditors.com/2026/01/06/h...

Now out in PLOS Biology- a novel clock mechanism regulating spawining in a newly-identified Clytia species : dx.plos.org/10.1371/jour...

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Congratulations to Byung Ho from the @anne-grapin.bsky.social lab @mpi-cbg.de and the rest of the team to this fantastic publication: www.nature.com/articles/s41...

🧵 Just out in Cell after more than 10 years in the making! 🎓 www.cell.com/cell/fulltex... Plants and animals evolve radically different body plans. Do they also operate under fundamentally different molecular evolutionary constraints during organ formation? @cellpress.bsky.social

Finally out! We studied the retinas of the longest-living vertebrate, the Greenland shark, and found that the retinas remain remarkably healthy in animals around 150 years old. What is the mechanism? It may be a highly efficient DNA repair system. Enjoy! www.nature.com/articles/s41...

Now online! Modeling human embryo implantation in vitro

HIF1α controls somitogenesis and spine development by regulating levels of intracellular oxygen in the presomitic mesoderm https://www.biorxiv.org/content/10.64898/2025.12.19.694009v1

Happy holiday ❄️⛄🎅! Global protein synthesis rates can fluctuate dramatically as a function of food intake, infections, energy resources, etc. Wondering whether/how protein elimination routes adapt to these changes to maintain proteome homeostasis ? Find out here: www.cell.com/cell-systems....

⏰ Last chance to save $250! Register by Dec 18 (11:59pm MST) for the Keystone Symposium on Stem Cell Models in Embryology. Join cutting-edge discussions on SCBEMs and their translational potential. hubs.la/Q03YlPvV0 #KSEmbryology26 #embryology @jun-wu-lab.bsky.social @ebisuyamiki.bsky.social

🎄 Day 16 of the 24 Days of Development ✨🧬 Ever wondered how electric eels develop their powerful electric organs?⚡️Discover how electrocytes form and differentiate during development ☃️ doi.org/10.1016/j.yd...

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

With further digging, we saw evidence that the stromal rhythm correlated with a change in its mechanical state (nuclear elongation and gene expression).

@azyhuang.bsky.social quantified this for the first time, finding that nephrons form from nephron progenitors that cap the tubule tips early (not in the middle or later) in the ureteric bud branching 'life-cycle' using a new 3D explant culture system she created. www.nature.com/articles/s41...

*New preprint alert* uncovering a mechanical pacemaker that synchronizes nephron formation with branching of the kidney's epithelial tubule tree. Read below to learn about this twisty journey lead by Sam Grindel and Sachin Davis in the lab. [Movie by Nils Lindstrom] www.biorxiv.org/content/10.1...

Planning to attend the Keystone Symposium on Stem Cell Models in Embryology? Save $250 by registering before Dec 18 (11:59pm MST)! Hear why this meeting is a must-attend from @jun-wu-lab.bsky.social: youtu.be/hKhc2VrbFj0 Register: keysym.us/KSEmbryology26 @ebisuyamiki.bsky.social #KSEmbryology26

Witnessed a flock of birds performing a mesmerizing group flight at a train station in Japan🕊️After circling for about 30 min, they gradually funneled back into their nest. And I missed a train

New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen

Like a kangaroo, the dinoflagellate 𝘊𝘪𝘵𝘩𝘢𝘳𝘪𝘴𝘵𝘦𝘴 𝘳𝘦𝘨𝘪𝘶𝘴 has a pouch. The pouch is called a phaeosome chamber, which houses symbiotic cyanobacteria (the orange cells). These cells have a free-loading roommate: an archaeal parasite.

Stephen R. Frankenberg et al. (2025) Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole Science Advances 11(1): eado4140 DOI: 10.1126/sciadv.ado4140 www.science.org/doi/10.1126/...

Programmed seasonal brain shrinkage in the common shrew via water loss without cell death: Current Biology www.cell.com/current-biol...

ゲノム言語モデルによる遺伝子のデザイン 機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。 時代の進歩に目が回ります、、 www.nature.com/articles/s41...

📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang. #Proteostasis #Aging #BiologicalClocks #Proteomics Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...