Nice summary on our paper on mechanisms controlling development and evolution of the cone-dominant ground squirrel retina, which is now in final form at eLife. www.lifescienceeditors.com/2026/01/06/h...

Now out in PLOS Biology- a novel clock mechanism regulating spawining in a newly-identified Clytia species : dx.plos.org/10.1371/jour...

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Congratulations to Byung Ho from the @anne-grapin.bsky.social lab @mpi-cbg.de and the rest of the team to this fantastic publication: www.nature.com/articles/s41...

🧵 Just out in Cell after more than 10 years in the making! 🎓 www.cell.com/cell/fulltex... Plants and animals evolve radically different body plans. Do they also operate under fundamentally different molecular evolutionary constraints during organ formation? @cellpress.bsky.social

Finally out! We studied the retinas of the longest-living vertebrate, the Greenland shark, and found that the retinas remain remarkably healthy in animals around 150 years old. What is the mechanism? It may be a highly efficient DNA repair system. Enjoy! www.nature.com/articles/s41...

Now online! Modeling human embryo implantation in vitro

HIF1α controls somitogenesis and spine development by regulating levels of intracellular oxygen in the presomitic mesoderm https://www.biorxiv.org/content/10.64898/2025.12.19.694009v1

Happy holiday ❄️⛄🎅! Global protein synthesis rates can fluctuate dramatically as a function of food intake, infections, energy resources, etc. Wondering whether/how protein elimination routes adapt to these changes to maintain proteome homeostasis ? Find out here: www.cell.com/cell-systems....

⏰ Last chance to save $250! Register by Dec 18 (11:59pm MST) for the Keystone Symposium on Stem Cell Models in Embryology. Join cutting-edge discussions on SCBEMs and their translational potential. hubs.la/Q03YlPvV0 #KSEmbryology26 #embryology @jun-wu-lab.bsky.social @ebisuyamiki.bsky.social

🎄 Day 16 of the 24 Days of Development ✨🧬 Ever wondered how electric eels develop their powerful electric organs?⚡️Discover how electrocytes form and differentiate during development ☃️ doi.org/10.1016/j.yd...

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

With further digging, we saw evidence that the stromal rhythm correlated with a change in its mechanical state (nuclear elongation and gene expression).

@azyhuang.bsky.social quantified this for the first time, finding that nephrons form from nephron progenitors that cap the tubule tips early (not in the middle or later) in the ureteric bud branching 'life-cycle' using a new 3D explant culture system she created. www.nature.com/articles/s41...

*New preprint alert* uncovering a mechanical pacemaker that synchronizes nephron formation with branching of the kidney's epithelial tubule tree. Read below to learn about this twisty journey lead by Sam Grindel and Sachin Davis in the lab. [Movie by Nils Lindstrom] www.biorxiv.org/content/10.1...

Planning to attend the Keystone Symposium on Stem Cell Models in Embryology? Save $250 by registering before Dec 18 (11:59pm MST)! Hear why this meeting is a must-attend from @jun-wu-lab.bsky.social: youtu.be/hKhc2VrbFj0 Register: keysym.us/KSEmbryology26 @ebisuyamiki.bsky.social #KSEmbryology26

Witnessed a flock of birds performing a mesmerizing group flight at a train station in Japan🕊️After circling for about 30 min, they gradually funneled back into their nest. And I missed a train

New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen

Like a kangaroo, the dinoflagellate 𝘊𝘪𝘵𝘩𝘢𝘳𝘪𝘴𝘵𝘦𝘴 𝘳𝘦𝘨𝘪𝘶𝘴 has a pouch. The pouch is called a phaeosome chamber, which houses symbiotic cyanobacteria (the orange cells). These cells have a free-loading roommate: an archaeal parasite.

Stephen R. Frankenberg et al. (2025) Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole Science Advances 11(1): eado4140 DOI: 10.1126/sciadv.ado4140 www.science.org/doi/10.1126/...

Programmed seasonal brain shrinkage in the common shrew via water loss without cell death: Current Biology www.cell.com/current-biol...

ゲノム言語モデルによる遺伝子のデザイン 機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。 時代の進歩に目が回ります、、 www.nature.com/articles/s41...

📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang. #Proteostasis #Aging #BiologicalClocks #Proteomics Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...

第5回　羽ばたく女性研究者賞 への応募受付中です。基礎研究あるいは研究開発に関わる、博士課程から独立直後あたりのキャリアステージの女性研究者の、表彰と応援が目的です。12月10日締め切りなので、自ら応募する、あるいは身近な対象者の背中を押してあげてください www.jst.go.jp/diversity/re...

Comparative genomics indicate multiple genetic routes to the evolution of torpor in placental mammals https://www.biorxiv.org/content/10.1101/2025.11.18.689136v1

最近のイチオシ漫画は「星旅少年」。話の展開を追うというよりは、綺麗な青色・小物のディテール・いいかんじのシチュエーションなどを、じっくり眺めて楽しむコミックアート。寝る前に部屋を暗くして電子書籍で読むと最高です。漫画の新しい楽しみ方を知りましたありがとう comics.pie.co.jp/series/hoshi...

🚨 Last call! Short talk abstracts & scholarship apps for Stem Cell Models in Embryology are due Nov 18 (11:59pm MST). Don’t miss your chance to join the lineup this February in Pacific Grove, CA. 🎥 youtu.be/g2DGgU2r7ao 🔗 keysym.us/KSEmbryology26 @jun-wu-lab.bsky.social @ebisuyamiki.bsky.social

“substantial phenotypic diversity already existed in early Holocene dogs” nice #domestixation study by @gregerlarson.bsky.social & collaborators in @science.org 🧪🐶🐾 www.science.org/doi/10.1126/...

Carnivorous 'death-ball' among odd deep-sea finds. 🧪 www.bbc.co.uk/news/article...

What is the origin of diversity in allometric laws scaling across species? Check our new paper led by Andrea Tabi where we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level. www.biorxiv.org/content/10.1...

And you can of course also go through to the q.e.d website: www.qedscience.com

“If your heart is beating really strong and fast, and you’re in a fear state, you don’t want to be sensitive to pain. You want to be able to run over broken twigs and glass to escape the threat,” said neuroscientist Sarah Garfinkel. www.quantamagazine.org/how-your-hea...

🌟 Countdown to Nov 4 (11:59pm MT)! Submit your short talk or scholarship app for #KSEmbryology26: Stem Cell Models in Embryology. Join @jun-wu-lab.bsky.social, @ebisuyamiki.bsky.social & global experts 🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26 #KSEmbryology26 #embryology #stemcells

Despite higher cell numbers and longer lifespans, large animals don’t have a higher cancer rate: Peto’s paradox. Elephants carry extra copies of tumor suppressor genes, while whales rely on enhanced DNA repair mechanisms! It’s fascinating that nature found different solutions to the same problem

From the nine-inch pygmy shark to a whale shark, the largest living fish, all sharks have the same surface area to volume ratio: a metric that might be a universal proportion across the natural world. www.quantamagazine.org/shark-data-s...

Join us @ #IETS2026 for our CANDES Precon keynote speaker, Miki Ebisuya, PhD (Physics of Life Dresden) 🎉. “Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰ Don't miss out—register by Dec 15 📆 to lock in early bird pricing! 🔗 https://bit.ly/3ILbB5r

Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it? Turns out we can harness the power of bacteria to power the world’s smallest machines. 1/7 ⚛️🧪

#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel! 📆 April 20-22, 2026 📍 Seattle, USA 🔬 All career stages welcomed. Apply to attend by 12/12: alleninstitute.org/events/aics-...

“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology” www.annualreviews.org/content/jour... This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪

mStayRose is published in JBC 🥳🎉 Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable: www.jbc.org/article/S002...

🚨 Late preprint alert! Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity! More in thread and here: doi.org/10.1101/2025...

This week’s round-up spans species from birds to sheep, and now, fittingly, to dogs! We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs. 🐕 Article: https://bit.ly/4gA5zkC 🐩 Discussion: https://bit.ly/4qfiME4

⏰ Last chance! Apply for a scholarship or submit your short talk abstract for Stem Cell Models in Embryology by Oct 21 (11:59pm MT). Join @jun-wu-lab.bsky.social & @ebisuyamiki.bsky.social this Feb for cutting-edge #stemcells & #embryology. 🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26

陸上生活に適応する耐圧メカニズム 陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御 着眼点が面白いです www.cell.com/cell/fulltex...

🇬🇧Are you experienced as an administrative manager and thrive in an #international environment? We would love to hear from you! Please share with those who might be interested! 🗓️Deadline: 30.10.2025 Apply here: tud.link/f4wf13

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

📢 New in @natbiotech.nature.com! Scientists have successfully derived #haploid androgenetic #ESCs from cattle and sheep and developed a novel method to generate offspring from these cells. 📖 Read the article: https://go.nature.com/48XR600 🎧 Listen to the discussion: https://bit.ly/4qfiME4

Lots of great discussion about developmental variability here at #GastrulationReloaded! Super important to consider, and current tools have the power for this. Related to this recent paper showing that mild phenotypes are more variable than severe ones. www.nature.com/articles/s41...

This meeting will be a significant event for those advancing research in stem cell-based embryo models. Submit your abstract and scholarship application by Oct 21! www.keystonesymposia.org/conferences/...

Vertebral skeletal diversity in mammals is remarkable. How do the differences between vertebral size and shape develop and evolve? See how we tackled this question in our paper published in @natcomms.nature.com today!