🚨 Last call! Short talk abstracts & scholarship apps for Stem Cell Models in Embryology are due Nov 18 (11:59pm MST). Don’t miss your chance to join the lineup this February in Pacific Grove, CA. 🎥 youtu.be/g2DGgU2r7ao 🔗 keysym.us/KSEmbryology26 @jun-wu-lab.bsky.social @ebisuyamiki.bsky.social

“substantial phenotypic diversity already existed in early Holocene dogs” nice #domestixation study by @gregerlarson.bsky.social & collaborators in @science.org 🧪🐶🐾 www.science.org/doi/10.1126/...

Carnivorous 'death-ball' among odd deep-sea finds. 🧪 www.bbc.co.uk/news/article...

What is the origin of diversity in allometric laws scaling across species? Check our new paper led by Andrea Tabi where we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level. www.biorxiv.org/content/10.1...

And you can of course also go through to the q.e.d website: www.qedscience.com

“If your heart is beating really strong and fast, and you’re in a fear state, you don’t want to be sensitive to pain. You want to be able to run over broken twigs and glass to escape the threat,” said neuroscientist Sarah Garfinkel. www.quantamagazine.org/how-your-hea...

🌟 Countdown to Nov 4 (11:59pm MT)! Submit your short talk or scholarship app for #KSEmbryology26: Stem Cell Models in Embryology. Join @jun-wu-lab.bsky.social, @ebisuyamiki.bsky.social & global experts 🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26 #KSEmbryology26 #embryology #stemcells

Despite higher cell numbers and longer lifespans, large animals don’t have a higher cancer rate: Peto’s paradox. Elephants carry extra copies of tumor suppressor genes, while whales rely on enhanced DNA repair mechanisms! It’s fascinating that nature found different solutions to the same problem

From the nine-inch pygmy shark to a whale shark, the largest living fish, all sharks have the same surface area to volume ratio: a metric that might be a universal proportion across the natural world. www.quantamagazine.org/shark-data-s...

Join us @ #IETS2026 for our CANDES Precon keynote speaker, Miki Ebisuya, PhD (Physics of Life Dresden) 🎉. “Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰ Don't miss out—register by Dec 15 📆 to lock in early bird pricing! 🔗 https://bit.ly/3ILbB5r

Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it? Turns out we can harness the power of bacteria to power the world’s smallest machines. 1/7 ⚛️🧪

#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel! 📆 April 20-22, 2026 📍 Seattle, USA 🔬 All career stages welcomed. Apply to attend by 12/12: alleninstitute.org/events/aics-...

“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology” www.annualreviews.org/content/jour... This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪

mStayRose is published in JBC 🥳🎉 Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable: www.jbc.org/article/S002...

🚨 Late preprint alert! Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity! More in thread and here: doi.org/10.1101/2025...

This week’s round-up spans species from birds to sheep, and now, fittingly, to dogs! We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs. 🐕 Article: https://bit.ly/4gA5zkC 🐩 Discussion: https://bit.ly/4qfiME4

⏰ Last chance! Apply for a scholarship or submit your short talk abstract for Stem Cell Models in Embryology by Oct 21 (11:59pm MT). Join @jun-wu-lab.bsky.social & @ebisuyamiki.bsky.social this Feb for cutting-edge #stemcells & #embryology. 🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26

陸上生活に適応する耐圧メカニズム 陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御 着眼点が面白いです www.cell.com/cell/fulltex...

🇬🇧Are you experienced as an administrative manager and thrive in an #international environment? We would love to hear from you! Please share with those who might be interested! 🗓️Deadline: 30.10.2025 Apply here: tud.link/f4wf13

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

📢 New in @natbiotech.nature.com! Scientists have successfully derived #haploid androgenetic #ESCs from cattle and sheep and developed a novel method to generate offspring from these cells. 📖 Read the article: https://go.nature.com/48XR600 🎧 Listen to the discussion: https://bit.ly/4qfiME4

Lots of great discussion about developmental variability here at #GastrulationReloaded! Super important to consider, and current tools have the power for this. Related to this recent paper showing that mild phenotypes are more variable than severe ones. www.nature.com/articles/s41...

This meeting will be a significant event for those advancing research in stem cell-based embryo models. Submit your abstract and scholarship application by Oct 21! www.keystonesymposia.org/conferences/...

Vertebral skeletal diversity in mammals is remarkable. How do the differences between vertebral size and shape develop and evolve? See how we tackled this question in our paper published in @natcomms.nature.com today!

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

Attention colleagues! Interested in an interdisciplinary #PhD? 🧬 Apply now for one of 12 PhD positions exploring biomolecular #condensates! This program involves several PoL PIs, bridging the gap between physics and biology. Apply here: dresdencondensates.org/join-us/ 🗓Deadline: 24. October

New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains 1/ doi.org/10.1101/2025...

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

🚨 New preprint out! “Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM” with Tithi Mandal and @rouxlab.bsky.social We benchmark and describe step-by-step Flipper-TR FLIM measurements across different set-ups and and strategies. www.biorxiv.org/content/10.1...

Congratulations to Fred Ramsdell, Mary Brunkow and Shimon Sakaguchi for winning the Nobel Prize in Physiology or Medicine! 🧪 #Nobel2025 www.nature.com/articles/d41...

Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

Really torn about Sanae Takaichi becoming Japan's first female prime minister. Historic moment, yes! But her ultra-conservative stance worries me. Ms Takaichi's against same-sex marriage, immigration, and even keeping maiden names(important for researchers) bbc.com/news/article...

Finally .. incredible much awaited wok on deriving avian naive ESCs “Derivation of embryonic stem cells across avian species” www.nature.com/articles/s41...

Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK. Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients. More here: elifesciences.org/reviewed-pre...

This meant that degradative machineries may be in charge: ✔️ differential abundance & stability of proteasomal particles ✔️ higher proteasomal activity in 🐭 compared to 👤 embryonic spinal cord

New paper from my lab and @jshendure.bsky.social lab! Led by the brilliant @zukailiu.bsky.social and @cxqiu.bsky.social. We tackled how anterior and posterior progenitor cells cooperate to self-organize into an embryonic structure (termed AP-gastruloid). (1/n) www.biorxiv.org/content/10.1...

EMBL scientists found metabolism controls embryonic development tempo through signalling in a way separate from its established metabolic function. More research related to this signalling could illuminate how it guides cell fate, developmental timing -- even disease. www.embl.org/news/science...

How many chromosomes can an animal have? In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact. www.cell.com/current-biol...

Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...

I am thrilled to share the main result of our work at @nordenlab.bsky.social with @liormoneta.bsky.social and @carldmodes.bsky.social . We bridged DevBiology + theoretical physics to understand how the eye becomes round #morphogenesis #devbio #biophysics #zebrafish www.biorxiv.org/content/10.1...

Scientists discover the secret behind the shrew’s amazing ability to shrink their brains 🧠 The clever trick sheds unwanted weight without compromising too much on cognition. Find the 5-letter word 👇 Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al www.ab.mpg.de/743885/news_...

Patterns of Mitochondrial ATP Predict Tissue Folding https://www.biorxiv.org/content/10.1101/2025.08.31.673364v1

Today marks the end of my summer project! It was exciting to head to the lab each morning, thinking about my experiments and data. I hope to share some interesting results in the future. This annual ritual also reminds me as a PI: most experiments don’t go as planned👩‍🔬

Many years in the making but now finally online! What determines the temperature scaling and thermal limits of cell cycle duration in embryos? We tackled the question using a combination of dynamical systems analysis and experimental measurements in embryos and in cycling Xenopus extracts.

Fausto, C. C., Glykofrydis, F., Kumar, N., Schnell, J., Csipan, R. L., De Kuyper, F., ... & Lindström, N. O. (2024). Defining and controlling axial nephron patterning in human kidney organoids with synthetic Wnt-secreting organizers. bioRxiv #EpithelialMechanics doi.org/10.1101/2024...

Wonderful joint retreat with Yang lab @poldresden.bsky.social! Renewed my enthusiasm for clarifying the energy budgets of diverse cells and organisms. Grateful to the organizers for putting together such a fun and creative event!

Final version @science.org "Recent evolution of the developing human intestine affects metabolic and barrier functions". Evolutionary preparation for microbiota, diet, and pathogen exposure is fascinating! Thank you @erc.europa.eu for supporting our vision! www.science.org/doi/10.1126/...