Pau Guillamat
@pauguillamat.bsky.social
📤 290
📥 267
📝 14
Active Nematics & Synthetic Morphogenesis
pinned post!
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter
#TissueEngineering
loading . . .
3 months ago
9
67
21
reposted by
Pau Guillamat
Max-Planck-Gesellschaft
3 days ago
Truly chuffed for our fearless food physicists
@mpipks.bsky.social
+ collabs from AT
@istaresearch.bsky.social
, IT & ES who won this year’s Ig Nobel - the
#NobelPrize
of hearts❤️for cracking the science of perfect pasta !🍝Kudos to all for intrepidly consuming lots of cheese in the name of science!😋
loading . . .
The Secret to a Smooth Pasta Sauce Wins Ig Nobel Prize
Italian researchers studied how the ingredients of the traditional Roman dish cacio e pepe emulsify into a creamy sauce, winning the 2025 Physics Ig Nobel Prize.
https://www.the-scientist.com/the-secret-to-a-smooth-pasta-sauce-wins-ig-nobel-prize-73487
0
62
21
reposted by
Pau Guillamat
Raphaël Clément
27 days ago
Mechanosensation and fast reorientation of ciliary structures: Marvin's work on the surprising locomotion capabilities of Trichoplax, an animal without neurons!
www.biorxiv.org/content/10.1...
loading . . .
1
67
22
reposted by
Pau Guillamat
Julia Eckert
about 1 month ago
Now published in
@natcomms.nature.com
! 🥳 👉
rdcu.be/eATn3
We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.
8
81
36
reposted by
Pau Guillamat
Anaïs Bailles
about 2 months ago
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS!
www.pnas.org/doi/10.1073/...
. We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
loading . . .
3
138
45
reposted by
Pau Guillamat
Ricard Alert Zenón
about 2 months ago
Dreaming of a swimming pool? Bacteria are surrounded by water! Water capillary forces organize bacterial colonies into gas, nematic streams, or droplet states. New paper
@natphys.nature.com
led by Matt Black and Chenyi Fei, with Ned Wingreen and Josh Shaevitz!
www.nature.com/articles/s41...
loading . . .
Capillary interactions drive the self-organization of bacterial colonies - Nature Physics
Bacteria tend to live in thin layers of water on surfaces. Now the capillary forces in these layers are shown to help organize the bacteria into dense packs.
https://www.nature.com/articles/s41567-025-02965-y
3
56
14
reposted by
Pau Guillamat
IBEC | Institute for Bioengineering of Catalonia
about 2 months ago
🔬#IBEC researchers create the world’s simplest artificial cell that can navigate using chemistry with just a membrane, an enzyme and a pore. A breakthrough on how life moves🧬 🧪
@science.org
#ScienceAdvances 🤝
@ub.edu
@liverpooluni.bsky.social
#IBEC
#ScienceAdvances
👉 Read the news:
https://f.mtr.cool/tzjomevovt
0
3
2
reposted by
Pau Guillamat
Claire Dessalles
2 months ago
Our study on endothelial mechanics made the news! 🤩 Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...
loading . . .
Here’s why your blood vessels don’t burst under pressure
Cells lining the blood vessels reorganize their inner structures to handle stressful boosts in pressure.
https://www.snexplores.org/article/how-blood-vessels-handle-pressure
3
31
11
reposted by
Pau Guillamat
Marija Matejčić
3 months ago
On cell extrusion in the
#intestine
! After 80 years of observations, we finally took a deeper look thanks to 2D
#organoids
. We report: 3D
#forces
,
#extrusion
still only in the villus even without curvature,
#lamellipodia
generate 3D force.. and more. Have a look!
www.biorxiv.org/content/10.1...
loading . . .
5
56
22
reposted by
Pau Guillamat
Xavier Trepat
3 months ago
🚨 Second preprint of the week! We uncover the multiscale dynamics of active viscoelastic buckling in epithelia. We harness these mechanical instabilities for synthetic morphogenesis. Led by
@onenimesa.bsky.social
🙌. Theory by Marino Arroyo etal.
@ibecbarcelona.eu
www.biorxiv.org/content/10.1...
loading . . .
4
76
22
reposted by
Pau Guillamat
Xavier Trepat
3 months ago
How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by
@pauguillamat.bsky.social
www.biorxiv.org/content/10.1...
loading . . .
4
115
29
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter
#TissueEngineering
loading . . .
3 months ago
9
67
21
reposted by
Pau Guillamat
Shashank Shekhar lab
6 months ago
📢Excited to share our new paper in Nature Physics
@naturephysics.bsky.social
: Cooperative hydrodynamics accompany multicellular-like colonial organization in the unicellular Stentor! How do single-celled organisms benefit from teamwork? Let’s dive in!
#Multicellularity
nature.com/articles/s41...
?
loading . . .
9
140
46
reposted by
Pau Guillamat
Erwin Frey
6 months ago
We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/
@fakhrilab.bsky.social
, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter. 🔗
www.nature.com/articles/s41...
#biophysics
#syntheticcell
#softmatter
loading . . .
1
134
43
reposted by
Pau Guillamat
Journal of Cell Science
6 months ago
In their Review, Laura Faure, Valeria Venturini
@valeriaventurini.bsky.social
and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro.
journals.biologists.com/jcs/article/...
0
42
21
reposted by
Pau Guillamat
James Briscoe
6 months ago
Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by
@biologyopen.bsky.social
More innovation from
@biologists.bsky.social
Details here:
www.biorxiv.org/content/10.1...
add a skeleton here at some point
1
69
26
reposted by
Pau Guillamat
epithelial mechanics fan club
7 months ago
What do star fish, snowflakes, and even cells have in common? I am
@juliaeckert.bsky.social
and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems.
#EpithelialMechanics
1
44
20
reposted by
Pau Guillamat
Dagmar Iber & CoBi
7 months ago
What a beautiful cover for our
#mechanobiology
paper "Morphometry and mechanical instability at the onset of epithelial bladder cancer":
doi.org/10.1038/s415...
- thx
@naturephysics.bsky.social
!! News & Views "Tissue wrinkles foreshadow cancer"
doi.org/10.1038/s415...
0
32
5
reposted by
Pau Guillamat
epithelial mechanics fan club
8 months ago
Shim, G., Breinyn, I. B., Martínez-Calvo, A., Rao, S., & Cohen, D. J. (2024). Bioelectric stimulation controls tissue shape and size. Nature communications, 15(1), 2938.
#EpithelialMechanics
https://www.nature.com/articles/s41467-024-47079-w
0
15
3
reposted by
Pau Guillamat
Julia Eckert
8 months ago
Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems!
www.biorxiv.org/content/10.1...
Huge thanks to all authors:
@tobyandrews.bsky.social
,Joe Pollard,
@rashmi-priya.bsky.social
,
@yap-lab.bsky.social
&Richard Morris Any 3D systems?👇
loading . . .
3
69
28
reposted by
Pau Guillamat
Roux Lab, Geneva
8 months ago
Yamini
@yamini-ravichan.bsky.social
changed the topology of Hydra to show that actin orientational defects of Hydra induce the full program of head regeneration:
www.science.org/doi/10.1126/...
Mechanics controls development! Thanks to Dan Pearce, Karsten Kruse, Matthias Vogg & Brigitte Galliot.
3
72
34
reposted by
Pau Guillamat
Xavier Trepat
10 months ago
🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by
@icfortunato.bsky.social
, theory by David Bruckner. Collaboration with
@raimonsunyer.bsky.social
and
@ehannezo.bsky.social
👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1
loading . . .
5
188
54
reposted by
Pau Guillamat
Mike Norton
10 months ago
abhorring an empty account, check out the recent work Piyush Grover and I published in PRE on bioinspired defect sensing in an active nematic. A big thanks to the community for all the discussions that inspired this work:
journals.aps.org/pre/abstract...
supported by DOE grant DE-SC0022280
loading . . .
0
8
3
reposted by
Pau Guillamat
Manuel Thery
10 months ago
Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
loading . . .
8
362
114
reposted by
Pau Guillamat
epithelial mechanics fan club
10 months ago
Cells are strong & generate forces while interacting with their environment. Traction Force Microscopy has been instrumental in measuring these forces, revealing the underlying mechanics. Let's explore pioneering papers in this 🧵by
@onenimesa.bsky.social
&
@juliaeckert.bsky.social
loading . . .
1
74
30
reposted by
Pau Guillamat
Benoit Ladoux
10 months ago
I am delighted to share our new preprint in which we reveal the crucial role for mechanical forces in myoblast fusion. Great work from Yoann, Sushil and Aleksandra and great collaboration with Christophe Marcelle and Amin Doostmohammadi!
www.biorxiv.org/content/10.1...
3
81
25
you reached the end!!
feeds!
log in