#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

👩‍🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky ! ▶️Taguez celles que vous connaissez, je les ajoute !

Super clear thread for super cool science!

I love the pearling instability at the end ! 😍 What happens in the happy attached flagellum to stabilize its tubular shape?

Most striking, in some instances of spontaneous flagellar detachment, the flagellum can glide on its own - mercilessly leaving the cell body behind, stabbing it on the way if need be (don't do this at home).

#SmoothMuscleCell #Piezo1 Small intestinal motility SMC Piezo1 KO in 4~6 wk-old🐭 👉Muscularis thinning 👉⏬Food consumption 👉⏬SMC density w/o⏫apoptosis 👉⏬small intestinal motility 👉⏬Muscularis Orai1/3 Trpc4 IP3R ⏫Cav1.2 Ano1 👉⏬carbachol-induced tension #CommsBio 2025 www.nature.com/articles/s42...

In the New and Notable "Pulling Frank-Starling into another dimension," Megan L. McCain highlights the paper "Biaxial length-tension relationship in single cardiac myocytes ." buff.ly/XliGXNu

CellPose 4.0 is a beast. Segmented human microglia, in brightfield. Credit to Sydney Houser.

Super excited that our group will be supported by an ERC Starting Grant! In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions. We'll have PhD and Postdoc positions available, please get in touch if interested!

New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌 @IBECBarcelona www.biorxiv.org/content/10.1...

Now published in @natcomms.nature.com! 🥳 👉 rdcu.be/eATn3 We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.

Very cool new paper by @thegulab.bsky.social published in Cell, showing that arterial endothelial coupling via gap junctions determines the speed and spread of vasodilation induced by neuronal activity ! #cerebrovascular #bloodflow #endothelium

Our study on endothelial mechanics made the news! 🤩 Super nice and clear article on our findings and their implications. www.snexplores.org/article/how-...

Nice discussions after the talk given online yesterday at cytophys.org, presenting the work of @pauguillamat.bsky.social @clairedessalles.bsky.social @yamini-ravichan.bsky.social @oriolmb.bsky.social and Tithi Mandal. Available on the lab youtube channel at: youtu.be/g-7HomnPdtk

I'm grateful for the Research Council of Finland for granting me the Academy Research fellowship! After getting over the shock I will soon move back to Finland to start as a group leader at the Institute of Biotechnology @helsinki.fi. Looking for a PhD student soon! www.aka.fi/en/about-us/...

Thank you @cp-newton.bsky.social for the very nice spotlight on our latest paper on endothelial mechanics! www.cell.com/newton/fullt...

Hi everyone! We are Newton, the flagship physics journal for Cell Press that launches in 2025. Starting our first post with an 🎇 EXCITING ANNOUNCEMENT 🎇 Our first article and Perspective are now online!!! Check them out @ www.cell.com/newton/newar... !

How can organs regenerate fast? Bioelectricity helps -- by coupling sub-second electrical injury signals to regenerative proliferation. First preprint from my potsdoc :D with @liujinghui.bsky.social @ritamateus.bsky.social @mpi-cbg.de and collaborators @mpipks.bsky.social @csbdresden.bsky.social

Super proud of superstar postdocs @nerlielisa.bsky.social and @liujinghui.bsky.social for our lab's most recent preprint! We uncover how wound-induced electrical currents are generated and transmitted in tissues, triggering proliferation, essential for organ #regeneration #bioelectricity #QBio 👇

Re-growing adult organs: mothers do it best Tomotsune Ameku from the lab of @irenemiguel-aliaga.bsky.social @crick.ac.uk tells the behind the paper story of their work looking into maternal intestinal growth in mice during reproduction: thenode.biologists.com/re-growing-a...

Preprint alert: 🧠🌊🦓-🐟 Have you ever wondered how molecules move around the brain? Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU. www.biorxiv.org/content/10.1...

Nematics in action in vivo! Smooth muscle cells (mis-)orientation and their active stress matters to dorsal aorta function.

Happy to officially introduce FilaBuster - a strategy for rapid, light-mediated intermediate filament disassembly. Compatible with multiple IF types, modular in design, and precise enough to induce localized filament disassembly in live cells. www.biorxiv.org/content/10.1...

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...

Just published!🎉 Excited to present Pickering lab's work on @pnas.org #IntussusceptiveAngiogenesis-On-A-Chip🤩 For 1st time in vitro, we rebuilt multicellular pillars composed of #EndothelialCells crossing a pressurized, flowing channel🤓 Kudos to our stellar Sabrina🌟 www.pnas.org/doi/10.1073/...

Very happy and excited to share our latest work linking actin nematodynamics and endothelial cell mechanics under anisotropic tension, now published in @natphys.nature.com ! rdcu.be/eigWi @ipparis.bsky.social @polytechniqueparis.bsky.social

Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...

Save the date: 2nd edition of The New Cardiobiology is coming Feb 2026 #EMBL Heidelberg! Join leaders in #vascular, #cardiac & #engineering research. Featuring a stellar lineup of speakers + many slots for oral presentations from submitted abstracts @khaase.bsky.social www.embl.org/about/info/c...

Thrilled to share our new review article! “The role of extracellular matrix viscoelasticity in development and disease” written together with Olivia Courbot is now published in npj Biological Physics and Mechanics. www.nature.com/articles/s44... #ECM #Mechanobiology #DevelopmentalBiology

🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint.bsky.social ! A huge thank you to @nicolettapetridou.bsky.social, Bernat, @crisp-c.bsky.social, Adrián, and everyone involved! 🙌 🧵⤵️

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

Incredible work beautifully summarized in this inspiring thread!

Hey #cell #biologists - I have noticed some really weird looking monster cells in my #epithelial cells (MCF10A) under certain conditions. They almost look neuronal, like they're forming some kind of synapses with multiple other cells they're sitting on top of. Anyone seen this before?

What do star fish, snowflakes, and even cells have in common? I am @juliaeckert.bsky.social and I would like to take you on a journey into the field of soft matter and give you a brief overview of experimental observations on symmetries in biological systems. #EpithelialMechanics

Calling all bioRxiv affiliates - bat signal is up as we have a big backlog. If you have time to screen some papers, we'd be eternally grateful! 🙏

4 more days to submit your abstract!! Don't miss the opportunity to come to Leuven and enjoy 4 days of #Mechanobiology: 🗣️ 15 amazing keynote speakers 🎤 Oral talks and poster sessions 📷 SciArt contest 🍻 Social activities 👉 Submit by 2nd March!! https://buff.ly/3CH94pW

New preprint out 🔥🔥 on my postdoc work with @manuelthery.bsky.social and @lblanchoin.bsky.social about how we can create sustained dynamic steady states of actin network inside microscopic wells that contract "forever" without collapsing! A thread 🧵 www.biorxiv.org/content/10.1...

Finally out! 🎉 Really happy to share my first co-author paper! It was wonderful to work with @aliperri.bsky.social , and huge thanks to @xaviertrepat.bsky.social for the opportunity to be part of this project. Grateful to the whole team for making this happen! www.nature.com/articles/s41...

New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). www.nature.com/articles/s41... @ibecbarcelona.eu

New actin probe from @veselin-nasufovic.bsky.social et al! SiR-XActin and its variants are more photostable and less perturbative than SiR-actin or FastAct. And it's already available from @spirochrome.com! With some beautiful data from @chillinwithpfn1.bsky.social: www.biorxiv.org/content/10.1...

Join us next week for the next set of talks from Gulmohar! This time, we have Bhargav Sanketi and @clairedessalles.bsky.social speak about their research. 🗓️February 11 ⏰ 6 PM IST Sign up here to attend the talks: forms.gle/bQZkKkJaH9UZ... @yamini-ravichan.bsky.social @nikhil-mishra.bsky.social

Today is a very special day for me: I just started as a permanent CNRS researcher at the Institute of Light and Matter! My research will focus on the physics of biological tissues and in particular the role of activity and anisotropy.🔬 @cnrs.bsky.social

Thrilled to share our new preprint on detecting the nematic orientation field on surfaces of 3D multicellular systems! www.biorxiv.org/content/10.1... Huge thanks to all authors: @tobyandrews.bsky.social,Joe Pollard, @rashmi-priya.bsky.social, @yap-lab.bsky.social &Richard Morris Any 3D systems?👇

If you are interested in mechanobiology of endothelial cells, here is one good review to read by @clairedessalles.bsky.social et al. www.nature.com/articles/s42...

Interesting findings by Jacob Notbohm's group. Nematic defects may form as a result of spatially coordinated patterns in cell forces and motion. 👉 arxiv.org/abs/2501.04827

Our paper "Morphometry and mechanical instability at the onset of epithelial bladder cancer" is now out in @naturephysics.bsky.social : rdcu.be/d5rTP #BladderCancer #Cancer #Tumor #Biomechanics #Morphometry #ComputationalModeling

The Institut Pasteur is recruiting group leaders! Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris. Come eat 🥐 and conduct awesome science. Contact me if you want info ! research.pasteur.fr/en/call/call...

I am putting some effort in keeping track of the conferences on Theoretical Biology and Quantitative Life Science. If you like to add some, please check this page. Help the community! sites.google.com/view/theoret...

It was a great pleasure to present my work at the In Vitro Organelles Subgroup at #CellBio2024 ! Many thanks to the organizers and everyone who came! I have my poster, B163, on Tuesday, the 17th at 11h15, to discuss more about membrane bending! @ascbiology.bsky.social @rouxlab.bsky.social

🧪🔬🦴 This is an #Osteocyte It lives in #bone and reaches out to #implants and #biomaterials through cellular extensions [ * ] It frequently talks to other osteocytes and orchestrates bone remodelling Be like the Osteocyte =) * Scanning electron microscopy ** Horizontal field width = 27 µm