Some people should never have access to students. “AI requires no ramp-ups, no meetings, and absolutely no emotional support…The issue is not whether my students are valuable. In long run, they are invaluable. The issue is that their value emerges slowly, whereas AI delivers immediate returns.”

We had covered the history of traction force microscopy (TFM) earlier: bsky.app/profile/epim... But what about applying TFM into more physiologically relevant systems, such as those in 3D? I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.

Barrasa-Fano, J., Shapeti, A., Apolinar-Fernández, A. et al. Guidance for 3D traction force microscopy today and in the next decade. Nat Methods (2025). #EpithelialMechanics buff.ly/eRFLGkt

Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics

Our paper on tissue stress measurements is now out in Eur. Phys. J. E. rdcu.be/eX59E. Great work from @luanger.bsky.social and @andreasschoenit.bsky.social and collaboration with P. Marcq @pmmh-lab.bsky.social Code: github.com/pmarcq/BISM/ and Examples on github.com/ASmushyCell/...

Reviewing process has always been painfull, but it will just become useless and impossible to publish if we start accepting this (we are not helping science...and better refusing to review if you have no time rather than using these tools without filter)

Tissue stress measurements — our latest preprint is out: arxiv.org/abs/2512.00550 (publication coming soon!) Fantastic work by the three musketeers — @luanger.bsky.social, @andreasschoenit.bsky.social and @fanny-wodrascka.bsky.social — in collaboration with P. Marcq!

Finally! 🤩 Our position piece: Against the Uncritical Adoption of 'AI' Technologies in Academia: doi.org/10.5281/zeno... We unpick the tech industry’s marketing, hype, & harm; and we argue for safeguarding higher education, critical thinking, expertise, academic freedom, & scientific integrity. 1/n

📢 PhD Thesis defense 📅 November 26th 📍Institut Jacques Monod Fanny Wodrascka ( @fanny-wodrascka.bsky.social @bladoux.bsky.social @rmmege.bsky.social ) will defend her PhD thesis "Mechanical control of epithelial cell extrusion via RhoA-dependent contractility " ➡️ buff.ly/f5VaVah

My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site #microscopy #ImageJ #FluorescenceFriday #microscopyMonday imagej.net/plugins/imag...

Truly honoured and grateful to have received alongside other young researchers the prize "Grandes avancées françaises en biologie" from the @academiesciences.bsky.social for our paper on mechanical cell competition together with @luanger.bsky.social and S. Monfared www.nature.com/articles/s41...

1/ 🐣⚒️ To study mechanics, we need to apply prescribed forces - how can we do that in living tissues? I am @eigenp.bsky.social and in this thread I'll highlight our new approach for applying tension on epithelial tissues in vivo!

Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal www.sciencedirect.com/science/arti...

Mechanobiology across timescales A Review by Bo Cheng, Moxiao Li, Min Lin, Hui Guo & Feng Xu ⚛️🧪 www.nature.com/articles/s42...

John M. Martinis, Michel H. Devoret & John Clarke recount the history of their milestone discovery, which today won the Nobel Prize in Physics go.nature.com/4gVswyS

We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy. mikeinmemoriam.sciencesconf.org

Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics. Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri! www.biorxiv.org/content/10.1...

As railways enter their third century of service, research must support their renaissance for more-sustainable travel that supports human development go.nature.com/3If7jTK

Science isn’t really moving towards equity; institutions are just perfecting the appearance of equity. We need to build an alternative system, says Dolors Armenteras go.nature.com/4nzGhp9

This comment in @natnano.nature.com is well worth a read ⚛️🧪

Tianxiang Ma, Valeriia Grudtsyna, Robin V. B\"olsterli, Amin Doostmohammadi: Cellular Flow Architecture Exposes the Hidden Mechanics of Biological Matter https://arxiv.org/abs/2508.17974 https://arxiv.org/pdf/2508.17974 https://arxiv.org/html/2508.17974

📢 Institut Jacques Monod Seminar 📅 September 11th 📍 Institut Jacques Monod Invited by @bladoux.bsky.social / @rmmege.bsky.social 's Lab , Stephanie Ellis ( @maxperutzlabs.bsky.social ) give the IJM Seminar "Understanding mosaic tissue dynamics through cell competition. " ➡️ buff.ly/V6LaKMz

📢 PhD Thesis defense 📅 September 11th 📍 Institut Jacques Monod Andreas Schoenit @andreasschoenit.bsky.social ( @bladoux.bsky.social / @rmmege.bsky.social Lab) will defend his PhD thesis "Mechanical forces in cell competition and epidermal stratification" More informations ➡️ buff.ly/yhtJMsu

Want to test your multicellular system? I have created a GitHub repository, ‘3D_SurfProps’, where you can download the MATLAB codes of our 3D surface analysis method: 👉 github.com/Julia-Eckert... Any questions, suggestions, or ideas for improvements? Please DM or email me. Have fun testing!

Now published in @natcomms.nature.com! 🥳 👉 rdcu.be/eATn3 We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.

To what extent does crowding modulate diffusion across the cytoplasm? Thrilled to contribute to this study alongside O. Destrian, M. Chabanon, and B. Goyeau! www.biorxiv.org/content/10.1...

Thanks Benoit! 😊 This is also the byproduct of your support and mentorship, and I was glad to be part of it. I'm really happy to share this prize with @andreasschoenit.bsky.social ! Unlike the cell competition, our work was steady and without fluctuations — I genuinely enjoyed every aspect of it.

Gupta, V. K., & Chaudhuri, O. (2022). Mechanical regulation of cell-cycle progression and division. Trends in Cell Biology, 32(9), 773–785. #EpithelialMechanicsReview linkinghub.elsevier.com/retrieve/pii...

Lång, E., Lång, A., Blicher, P., Rognes, T., Dommersnes, P. G., & Bøe, S. O. (2024). Topology-guided polar ordering of collective cell migration. Science Advances #EpithelialMechanics doi.org/10.1126/scia...

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...

3D cell cultures better mimic real tissues than 2D—but how do we image them? This review explores 2D & 3D microscopy techniques for studying 3D cultures, highlighting strengths, limitations, and future innovation needs. #microscopy #bioengineering @naturemethods.bsky.social

Exploring the Frontiers of #Mechanobiology Mechanobiology Conference III, organized by Prof. @bladoux.bsky.social ( #MPZPM), takes place July 6–12, 2025 in Vietnam. Topics include cell signaling, biomaterials & more. 📅 Deadlines: Abstracts – Apr 30 | Reg – Jun 6 👉 icisequynhon.com/conferences/...

#RésultatScientifique🔎 La force cachée des cellules @bladoux.bsky.social et @rmmege.bsky.social et leurs collaborateurs révèlent que l’adhésion intercellulaire joue un rôle clé dans la compétition cellulaire, influençant le développement et la lutte contre le cancer.

What happens between cells with adhesion differences in crowded tissues? Mechanical cell competition! Check the final version of our study to learn more about compression-independent cell elimination, interactions at tissue interfaces and the role of force transmission in that tinyurl.com/4yw97bm3

Happy to share our new publication in @naturematerials.bsky.social on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats @luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉 www.nature.com/articles/s41...

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

Bayesian Force Inference is now on GitHub! Together with GetVertex, an ImageJ/Fiji plugin for extracting input data from skeletonized images, this enables code-free quantification of forces during epithelial development. github.com/Sugimuralab/...

As the world of science wakes up to modern fascism, it's worth remembering older generations who stood up for humanity in much harsher circumstances. Jacques Monod worked actively for the resistance in WWII, while pursuing early stages of his research in occupied Paris. @standupforscifr.bsky.social

On March 7, let's stand up for science! 🔬✊ In solidarity with Stand Up For Science US (@standupforscience.bsky.social) and in response to threats against scientific institutions, actions will take place in every university city in France. Info & registration 👉 standupforscience.fr

How can we investigate the mechanical state of cells within a tissue, assessing if they are under compression or tension? @luanger.bsky.social and I highlight methods in a short 🧵 with @epimechfc.bsky.social

Roffay, C., Chan, C. J., Guirao, B., Hiiragi, T., & Graner, F. (2021). Inferring cell junction tension and pressure from cell geometry. Development (Cambridge, England), 148(18), dev192773. #EpithelialMechanicsReview journals.biologists.com/dev/article/...

We have a new #stopdoing #science meme, courtesy of Miquel Bosch Padros from the @xaviertrepat.bsky.social lab. Late for #mechanobiology Monday, but here to stay on your lab meme boards forever.