🔬 #ImageOfTheWeek powered by the #PelletierLab Stunning imaging from recent work of Philip et al. (2025) in #EMBOJournal: tinyurl.com/3p44bh9y Thanks to the team at Lunenfeld-Tanenbaum Research Institute @sinaihealth.bsky.social, #Nikon CoE & NBCC Imaging Facility #FluorescenceFriday #V3UpgradeToSIM

It's #FluorescenceFriday and these retinal astrocytes understood the assignment: branching, glowing, and casually laying down the blueprint for the retinal vasculature #Retina #ConfocalMicroscopy

🪱 Serving head-to-tail fluorescence 💅 Whole-animal FISH in the planaria Schmidtea mediterranea: 🔵 Head 🟣 Gut 🟡 Tail ✨ Masters of regeneration and color coordination 📸 Image from Viraj Doddihal #FluorescenceFriday To be featured submit your images here ➡️ forms.gle/PWyaViekkNNn...

Mammalian membranes are thought to universally avoid macroscopic solidification, as reduced fluidity impairs plasticity and protein function. Cells counter this via lipid unsaturation and cholesterol buffering. However, the ER is deliberately cholesterol-poor to maintain high-curvature membranes!/5

#FluorescenceFriday - experiments take so long (especially for PIs that moonlight as postdocs), between breeding, tamoxifen, waiting for the 🐭 to grow up, slicing, clearing, staining for CD206 then finding a chunk of time on the 🔬...but then I get to image all my fav cells & it's SO worth it. ❤️

✨ This Xenopus 🐸 tadpole came to #FluorescenceFriday serving eye-conic energy 👀 Stage 39 eye stained with a whole rainbow: 💙 DAPI | ❤️ Acetylated tubulin | 💚 RPE | 🩵 Rhodopsin | 💜 Pax6. 📸 Image from Jian Sun.

Going through some old microscopy data, and I have to say - I maintain that #mitochondria are the most beautiful organelles, but the #ER might be a very close second. #FluorescenceFriday Live HeLa cells, ER imaged by STED, mitochondria with confocal.

Cellular Liquid Gold 🔬 This time-lapse shows an A549 cell over-expressing Sec61B, outlining the Endoplasmic Reticulum. Imaged at 1 frame per 500ms, it reveals just how violently active our cellular infrastructure really is! What is your favorite organelle to image? 👇 #SciArt #FluorescenceFriday

Copy paste into the address bar of your browser for a random generative artwork. No AI involved.

Striking microtubule-actin compartmentalization. A cell so big must organize things I guess!

I'm so pleased to see this work on neural crest development out in Nature today! This was a truly fantastic collaboration with @gleesonlab.bsky.social, Keng loi (Harry) Vong and @xiaoxuyang.bsky.social. Huge thanks to everyone involved 👏 🧪🐣 #devbio www.nature.com/articles/s41...

Oligodendrocyte precursor cell in the spinal cord of a transgenic zebrafish larva. Credit to @jiaxingli.bsky.social. #ZebrafishZunday 🧪

Chromosomes stuck behind the spindle are ticking time bombs for aneuploidy. We uncovered a mechanical rescue mechanism where microtubule pivoting repositions these high-risk chromosomes! Out last week in @natcomms.nature.com, here's a thread 🧵 shorturl.at/OD89x

dissecting & combating #CNS #scarring

Reactive microglia (🟠) and astrocytes (⚪️) as well as Aβ plaques (🔵) in the hippocampal dentate gyrus of a 5xFAD mouse model of Alzheimer's disease. #FluorescenceFriday

🥚 Egg hunt but make it neuroscience & microscopy for #FluorescenceFriday !💐 With Easter around the corner, I'm sharing some of my latest imaging & sciart work: mouse olfactory bulbs made to look like beautiful Fabergé eggs! 👑 The images were taken from 3D datasets of whole cleared mouse brains.

Fluorescence Friday - Massage edition ! 🤏 By @pierre-bercier.bsky.social #CellBiology #Microscopy #Nucleus #FluorescenceFriday @crg.eu @prbb.org

✨ Somite symmetry never fails to mesmerize 🐟 Trunk somites of a 1-day-old zebrafish embryo with nuclear (💙) and membrane (🧡) labelling 📸 Image credit: Matyas Bubna-Litic (Mongera lab, UCL) 🔬 #FluorescenceFriday

#Cilia are beautiful! That's it, that's the tweet. Oh, and Happy #FluorescenceFriday 🔬

Finished your PhD & looking for a Postdoc position? Intrigued by #zebrafish heart morphogenesis? Job available in the @rashmi-priya.bsky.social Lab at @crick.ac.uk (Initial 4 years funding w/ potential for 2 additional years)🐟❤️ More details: crick.wd3.myworkdayjobs.com/External/job... Please share 🧪

Please check out our newest work on fluorogenic speed imager probes, in which we combine the strengths of speed-optimized imagers and fluorogenic imagers. #SuperResolution #DNAPAINT #microscopy www.biorxiv.org/content/10.6...

Microscopic views of a Walnut stem. #Photography #Photos #Microscopy #ElectronMicroscopy

Geek o'clock: 3D-rendering your own MRI

Having fun with Louis' data #FluorescenceFriday

Follow-up from last week’s #FluorescenceFriday 🐟✨ Took a closer look at the gill comb “tooth” — the actin microridges of the enveloping epithelial layer almost look like microscopic fingerprints, each with a distinct pattern #Zebrafish #DevBio #Microscopy #SciArt

#Zebrafish🐟 #Pericyte Progressive mural cell deficiencies across the lifespan in a foxf2 model of cerebral small vessel disease #SciArt from Dr. Sarah Childs lab😍 #eLife 2026 elifesciences.org/articles/106... Cleared wild-type 3-mpf 🐟brain pdgfrβ (blue) kdrl (red)

For #MicroscopyMonday: “Seeing Every Photon”—a hands-on workshop with Evident Scientific on the FLUOVIEW FV4000 confocal! At the Fall symposium Nov 6-7, learn to capture consistent, quantitative images with SilVIR™ detectors and performance monitoring. #NESM #ConfocalMicroscopy

🦋 Butterfly wings form from invisible developmental boundaries long before their colors appear.🏆Congrats to Gabby Jerz, Poster Winner from the #NESM Fall Symposium and Lab Manager in the Patel Lab at the MBL @mblscience.bsky.social. 🔬 Zeiss LSM880 #MicroscopyMonday #Bioimaging #DevBio

Looking through old photos and found this beauty. Frog rods, labelled with GFP under a XOP promoter (inner segment, orange) and wheat germ agglutinin (outer segments, cyan). I love how you can see the holes where the mitochondria are packed near the top of the inner segment (the ellipsoid zone). 🧪🐸

Optical clearing & time-lapse fluorescent imaging of Live mouse Brain (up to 800 μm of depth)🤯 An acute olfactory bulb slice(P11) loaded with GCaMP6f (Ca2+ sensor) was imaged with #2PM at a depth of 150 μm during clearing with SeeDB-Live👹 #NatMethods 2026 www.nature.com/articles/s41...

Confocal micrograph of a transgenic adult zebrafish heart with cardiomyocytes in 🧡, blood vessels in 🩷, and cell nuclei in 💙. Credit to Dr. Aaron Scott (prev. w/ @beckrichardson.bsky.social @bristoluni.bsky.social). #ZebrafishZunday 🧪

Excited to have started my new lab in Human Genetics at Pitt Public Health! We study wound healing in diabetes & aging using adult zebrafish. Check out this movie showing neutrophil dynamics after injury. Now recruiting research staff, grad students, and postdocs. DM me if interested.

Neural crest cells beginning their long trek out of the neural tube in a quail embryo. Beautifully captured by the fantastic @siewzhuan.bsky.social 🧪🐣🔬

Kaleidoscopic view of my tracing experiment, from top to bottom. Our great achievement with @jeremie-bic.bsky.social in @bic-bordeaux.bsky.social for @imn-bordeaux.bsky.social

Myself and @immunoah.bsky.social are looking to hire a postdoctoral scientist to build a next-generation high-throughput high-resolution light sheet microscope for imaging entire cleared organs/tissues and to further develop live & fixed tissue clearing methods. www.nature.com/naturecareer...

#FluorescenceFriday "Into the Cellular Galaxy" HeLa cells were labeled with dual organelles targeting fluorophore named DOBEL (that was synthesized by Dr. Barsha Chakraborty, PhD, IISER Bhopal) #Microscopy #LifeSciences #Imaging

Our fantastic #FluorescenceFriday featured image was acquired by @juliazheku.bsky.social, a graduate student with @aribidopsis.bsky.social. The image shows a maize cross section, with a developing nodal root breaking through the basal stem node. Check out our post ⤵️:

A solar flare erupting on a glass coverslip ☀️🔬 This mouse cell has broken symmetry, erupting to drive itself across the surface. 🧡 Actin: Sweeping golden kinetic energy 🩵 Septin 7: Swirling membrane regulation 🩷 Lipids: Burning metabolic fuel 💙 DNA: The anchored core #SciArt #FluorescenceFriday

Just combed through my old data… et voilà: a tooth of the gill comb. 🐟✨ #FluorescenceFriday #zebrafish #DevBio #SciArt

Happy #FluorescenceFriday all! Checkout these beautiful basal bodies in airway #multiciliated cells expanded via U-ExM 😍 Images captured by the super talented @maneesha07.bsky.social on a #Nikon NSPARC 🔬.

1st McKinley Lab grad student’s 1st preprint! @claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy. Come for her GORGEOUS images, stay for her incredible discoveries. www.biorxiv.org/content/10.6... w/ @akelleher1017.bsky.social

Just discovered the wonderful covers of 'Genes to Cells', the journal of the Molecular Biology Society of Japan @mbsj-official.bsky.social – absolutely beautiful! here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments

Best buddies? More like budding buddies 🪼👯‍♀️✨ Six stages of asexual budding in Hydra to generate new genetically identical individuals (clones). 🟣: collagen 🟢: stem cells. 📸 Image by Ben Cox #FluorescentFriday

First 24 hours of embryonic development in 9 different animal species: (From left to right) Zebrafish, Sea urchin, Black widow spider, Tardigrade, Sea squirt, Comb jelly, Parchment tube worm, Roundworm, Slipper snail. Credit to @tessamontague.bsky.social & Zuzka Vavrušová. #ZebrafishZunday #devbio 🧪

Finally got the SIM perfectly calibrated on all four channels 🌈 (movie shows a 15x15 μm area inside a cell) #realtimemicroscopy

#ImageOfTheMonth March 2026 Dividing Arabidopsis epidermal cells imaged by confocal microscopy after expansion. Microtubules guided cell plate formation revealed in 3D with depth-code. Image: Magali Grison @lbm-bordeaux.bsky.social @gtexm.bsky.social #Microscopy #PlantScience #CellBiology

I found this immune cell (🔴) prying open the junction between the ectoderm cells from underneath. You can see its protrusions probing (yellow arrow) and threading through between the other cells before the whole cell body is squeezed through in 1 sweeping motion. So cool! #FluorescenceFriday

It’s #FluorescentFriday! This Maximum Intensity Projection of LUHMES-derived neurons shows: 🟦 Vimentin (@proteintech.bsky.social Cat No. 10366-1-AP) 🩷 Tubulin 🧡 Actin 🤍 DNA Explore the antibody: www.ptglab.com/products/VIM... #Proteintech #Neuroscience

Have you produced beautiful images as part of your cell biology research? Then enter our image competition! bscb.org/competitions... Deadline 31st March Check out last year's winner 'Brainbow' by Alvaro Castano