HAK-actin™: a new probe to label #actin in your expansion microscopy samples with a robust yet simple protocol. Find out how HAK-actin™ can help you achieve a bright actin staining in your ExM workflow: spirochrome.com/product/hak-... Image credits: Olivier Mercey, UNIGE

Congrats to @errricpeterman.bsky.social on leading our latest paper now published in @jcellsci.bsky.social ! Eric found multiple roles for microtubules in tissue-resident macrophage homeostasis and function -- including in helping macrophages navigate around epithelial obstacles during wound repair👇

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

Have you ever wondered how microtubules withstand and respond to mechanical stress in cells? Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

You asked for it! We delivered Quack-O-Grams to our members of Congress urging them to #ImpeachRFK, and get that Quack out of office! There's still time for you to get in on this fluffy, feathery action: Send your own duck at zurl.co/W1ZnB#ImpeachRFKand keep the momentum going! 🦆

🚨Great News!🚨 Our latest preprint is now live on bioRxiv! We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress. Congrats @marianattom.bsky.social www.biorxiv.org/content/10.1...

I’ll use this opportunity to highlight Tim Mitchison’s article in #MBoC It’s not all about targeting cell division! #microtubule #MTA #cytoskeleton

Murine centrosomal proteins with non-mitotic cytoskeletal side gigs. The numbers are SDS-PAGE migration values converted to estimated "kiloDaltons". #proteomics

🎉New Paper Drop🎉 We just uploaded our latest findings on bioRxiv! We report the identification of the limits of microtubule self-repair and how microtubule integrity is maintained under mechanical load. Congratulations @bucklingmt.bsky.social www.biorxiv.org/content/10.1...

Love a good tutorial …

Exciting new work from the #Schaedel lab on the limits of microtubule self repair > will help us understand how #microtubules experiencing extreme compression in crowded 3D environments resist or give way.

🩻 Capturing the Cytoskeleton of Mesenchymal Cells ⚪ Microtubules (grey) 🔵 Actin filaments (blue) 🟣 Nuclei (magenta) Credit: Image to Micaela Lasser and Helen Willsey for the great work getting this image!

Are you ready for a symposium dedicated to microtubule dynamics, function, and structure? 🙌 #EESMicrotubules will bring together researchers who share an interest in microtubule biology and its relevance to health and disease 🩺 💻 s.embl.org/ees26-09-bl#EESMicrotubules✒️ Submit your abstract by 11 March

Maru the cat died. May cat heaven be full of boxes that are just a little too small.

A new transgenic quail model supports live imaging of embryogenesis and mirrors early human morphogenesis such as junctional neural tube formation, which @melaniedwhite.bsky.social lab is studying the link between PRICKLE1 gene and apical mechanical forces behind it. #MBIMPG2025

Thanks for sharing our work @bladoux.bsky.social (you just made the lead author @marcoenriquez18.bsky.social very happy 😊)

Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions | Science Advances www.science.org/doi/10.1126/...

Important point!

Working from home, reviewing papers (before I travel later this month) & getting ready to chair a Viva this arvo 👉my coworkers are trying to distract me #CatsOfAcademia #AustralianMist

📣”#Fertility is compromised after oocyte-specific #deletion of microtubule severing protein #KataninA1” #oocytecompetence #meiosis #microtubules #spindle 📚🔗Dive into the full article 👇 academic.oup.com/molehr/artic...

The non-inhibitory serpin Maspin (SerpinB5) directly binds to microfilaments and microtubules in vitro and in cells, acting at the interface between the cytoskeleton and adhesion sites. www.nature.com/articles/s42...

Who say what now?!! BLUEY THE MOVIE?!! #bluey #myChildWillBeTooOldButIllStillGo www.bluey.tv/blog/date-an...

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton https://www.biorxiv.org/content/10.1101/2025.08.29.673170v1

Join an exchange between data scientists, experimental biologists, mathematical modelers and biophysicists at the Machine Learning of Cytoskeletal Machines (Cell Migration and Mitosis) workshop! Apply today at www.nitmb.org/cytoskeletal...

Supracellular actomyosin assemblies: master coordinators of development In this Review, Katja Röper @katjaroeper.bsky.social discusses supracellular actomyosin structures, tissues where they function, their known roles as well as potential properties journals.biologists.com/dev/article/...

Some first raw (not deskewed) data of live human induced pluripotent stem cells from #Snouty now ready for some serious live imaging. Light sheet moving at a 38-degree angle through the cell layer; coverslip is on the bottom.

📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT. RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected]. More info: www.shekharlab.org

Our new paper is out! 🎉 We show how microtubules may help traffic matrix proteins into the biomineralization compartment. Congrats to the team for this beautiful work! 🔗 anatomypubs.onlinelibrary.wiley.com/doi/full/10....

Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳 Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻 Enjoy the reading www.nature.com/articles/s41...

Always nice to see the field moving forward! Paper out from the White lab in @nature.com today! www.nature.com/articles/s41.... #Microtubules conferring #mechanical resistance to compression in melanoma cells > similar to our findings in @natcellbio.nature.com doi.org/10.1038/s415... ☝️

Fellow #cytoskeleton & #mechanobiology lovers> Alexis finally made the jump @alexis-lomakin.bsky.social

Trying to squeeze in some work at home. This one is blocking my keyboard. Time to stop #catsofacademia

Heading to Biomatter: From Cytoskeleton to Embryo in Arolla? Don’t miss our PhD student @prajwal08.bsky.social at poster #44! Come hear about his cool work on #osmoregulation during #embryogenesis. #Arolla2025

A cell's internal spin direction results from myosin chirality – insight into how left-right symmetry is broken in certain tissues & organs 📷 Takaki Yamamoto et al @riken-bdr.bsky.social in @elife.bsky.social ➡️ bpod.org.uk/archive/2025... with Lux Fatimathas

wow.... opto-myosin mini-filaments that can switch speed or direction upon illumination! cool new work from Zev Bryant and colleagues. www.biorxiv.org/content/10.1...

Engineering filamentous myosins for optical control of contractility https://www.biorxiv.org/content/10.1101/2025.08.19.666446v1

We are excited to share our latest work elucidating the structural basis for how augmin binds to microtubules. Out just now @natcomms.nature.com : www.nature.com/articles/s41...

This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue.

Well that was unexpected for a Saturday morning in Australia…. #earthquake

I maintain my stance: WHITE SPACE in #grants is worth **more** to your assessors than the extra information you have crammed in. My heart sinks when I get a wall of writing….

For the second time- I’ve read a paper published this week claiming they’re altering #microtubule #mechanobiology / #mechanotransduction and they don’t cite the **primary papers**. Don’t do this…give credit to the authors who did the hard yards. Not sure which ones to cite? Just ask.

Microtubule acetylation by TAT1 is essential for touch sensation in zebrafish but dispensable for embryonic development https://www.biorxiv.org/content/10.1101/2025.08.07.669193v1

Stunning photograph of Mitochondria by Torsten Wittmann (@microtubule.bsky.social), USCF "mitochondria were stained in bright yellow to visualize them in the cell. The large blue dots are the cell nuclei and the gray web is the cytoskeleton of the cells." www.flickr.com/photos/nihgo...

Calcium chelation promotes microtubule regrowth and axonal recovery after laser-induced axonal injury https://www.biorxiv.org/content/10.1101/2025.08.08.668418v1

Microtubule architecture connects AMOT stability to YAP/TAZmechanotransduction and Hippo signaling https://www.biorxiv.org/content/10.1101/2025.08.08.669326v1

In @jcb.org, Geng et al. find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors rupress.org/jcb/article/...

ICYMI: The images alone will melt your heart— This issue’s cover image features work by Perundurai S. Dhandapany & team on a genetic variant of tubulin tyrosine ligase that perturbs microtubule tyrosination in hypertrophic cardiomyopathy: buff.ly/gou4hF1

That childhood in the Australian sun gets expensive in your 40s! 6 monthly check up post #melanoma in situ. 🫠 (but it likely saved my life- I’m very thankful to have such a great #Dermatologist)

Actin fell in love with nucleus ❤️ #actin #cytoskeleton #nucleus #microscopy #cellbiology #research