(@ingohelbig.bsky.social)

Different genes, convergent processes – rare disease lessons from neurogenesis A paradox in the hippocampus. Immature dentate granule cells are often described as the “plasticity reserve” of the hippocampus. They provide a pool of neurons that integrate into existing circuits, supporting learning,…

loading . . .

Different genes, convergent processes – rare disease lessons from neurogenesis A paradox in the hippocampus. Immature dentate granule cells are often described as the “plasticity reserve” of the hippocampus. They provide a pool of neurons that integrate into existing circuits, supporting learning, memory, and repair. In neurological disease, these cells have been suggested to buffer against injury or degeneration. In a recent publication, researchers showed that the hippocampus continues to generate new neurons throughout life, but that the molecular instructions for doing so vary dramatically across species. https://epilepsygenetics.blog/2025/08/26/different-genes-convergent-processes-rare-disease-lessons-from-neurogenesis/